Combined blood transfusion and hydroxycarbamide in children with sickle cell anaemia

British Journal of Haematology

Volumn 160, Issue 2, 2013, Pages 259-261

  Brousse, Valentine ^a   Gandhi, Shreyans ^b   de Montalembert, Mariane ^a   Height, Sue ^b   Dick, Moira C ^b   O'Driscoll, Sandra ^b   Abihsera, Gaëlle ^a   Rees, David C ^b  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

^b KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Blood transfusion; Hydroxycarbamide; Sickle cell anaemia; Stroke

Indexed keywords

HEMOGLOBIN; HYDROXYUREA;

ADOLESCENT; BLOOD TRANSFUSION; BRAIN INFARCTION; CEREBROVASCULAR DISEASE; CHILD; CLINICAL ARTICLE; CORONARY ARTERY OBSTRUCTION; DISEASE COURSE; DRUG WITHDRAWAL; FEMALE; HEMOGLOBIN BLOOD LEVEL; HOMOZYGOTE; HUMAN; LABORATORY TEST; LETTER; LEUKOCYTE COUNT; MALE; MEDICAL AUDIT; MOYAMOYA DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PATIENT SAFETY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; SICKLE CELL ANEMIA; SIDE EFFECT; STEADY STATE; TRANSIENT ISCHEMIC ATTACK;

ADOLESCENT; ANEMIA, SICKLE CELL; BLOOD TRANSFUSION; BRAIN ISCHEMIA; CEREBRAL INFARCTION; CEREBRAL REVASCULARIZATION; CEREBROVASCULAR DISORDERS; CHILD; COMBINED MODALITY THERAPY; DISEASE PROGRESSION; FEMALE; HEMOGLOBINS; HUMANS; HYDROXYUREA; LEUKOCYTE COUNT; MALE; MOYAMOYA DISEASE; RECURRENCE; RETROSPECTIVE STUDIES;

EID: 84872231277     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.12104     Document Type: Letter

References (10)

1. Adams, R.J. (2000) Stroke prevention in sickle cell disease. Current Opinion in Hematology, 7, 101-105.
2. Bernaudin, F., Verlhac, S., Arnaud, C., Kamdem, A., Chevret, S., Hau, I., Coic, L., Leveille, E., Lemarchand, E., Lesprit, E., Abadie, I., Medejel, N., Madhi, F., Lemerle, S., Biscardi, S., Bardakdjian, J., Galacteros, F., Torres, M., Kuentz, M., Ferry, C., Socie, G., Reinert, P. & Delacourt, C. (2011) Impact of early transcranial Doppler screening and intensive therapy on cerebral vasculopathy outcome in a newborn sickle cell anemia cohort. Blood, 117, 1130_1140; quiz 1436.
3. Brousse, V., Hertz-Pannier, L., Consigny, Y., Bresson, J.L., Girot, R., Mirre, E., Lenoir, G. & de Montalembert, M. (2009) Does regular blood transfusion prevent progression of cerebrovascular lesions in children with sickle cell disease? Annals of Hematology, 88, 785-788.
4. Dobson, S.R., Holden, K.R., Nietert, P.J., Cure, J.K., Laver, J.H., Disco, D. & Abboud, M.R. (2002) Moyamoya syndrome in childhood sickle cell disease: a predictive factor for recurrent cerebrovascular events. Blood, 99, 3144-3150.
5. Miller, S.T., Sleeper, L.A., Pegelow, C.H., Enos, L.E., Wang, W.C., Weiner, S.J., Wethers, D.L., Smith, J. & Kinney, T.R. (2000) Prediction of adverse outcomes in children with sickle cell disease. New England Journal of Medicine, 342, 83-89.
6. Ohene-Frempong, K., Weiner, S.J., Sleeper, L.A., Miller, S.T., Embury, S., Moohr, J.W., Wethers, D.L., Pegelow, C.H. & Gill, F.M. (1998) Cerebrovascular accidents in sickle cell disease: rates and risk factors. Blood, 91, 288-294.
7. Rees, D.C., Porter, J.B., Clegg, J.B. & Weatherall, D.J. (1999) Why are hemoglobin F levels increased in HbE/beta thalassemia? Blood, 94, 3199-3204.
8. Rees, D.C., Williams, T.N. & Gladwin, M.T. (2010) Sickle-cell disease. Lancet, 376, 2018-2031.
9. Scothorn, D.J., Price, C., Schwartz, D., Terrill, C., Buchanan, G.R., Shurney, W., Sarniak, I., Fallon, R., Chu, J.Y., Pegelow, C.H., Wang, W., Casella, J.F., Resar, L.S., Berman, B., Adamkiewicz, T., Hsu, L.L., Ohene-Frempong, K., Smith-Whitley, K., Mahoney, D., Scott, J.P., Woods, G.M., Watanabe, M. & Debaun, M.R. (2002) Risk of recurrent stroke in children with sickle cell disease receiving blood transfusion therapy for at least five years after initial stroke. Journal of Pediatrics, 140, 348-354.
10. Ware, R.E., Zimmerman, S.A., Sylvestre, P.B., Mortier, N.A., Davis, J.S., Treem, W.R. & Schultz, W.H. (2004) Prevention of secondary stroke and resolution of transfusional iron overload in children with sickle cell anemia using hydroxyurea and phlebotomy. Journal of Pediatrics, 145, 346-352.