Fenretinide Causes Emphysema, Which Is Prevented by Sphingosine 1-Phoshate

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Yasuo, Masanori ^a,b   Mizuno, Shiro ^a   Allegood, Jeremy ^a   Kraskauskas, Donatas ^a   Bogaard, Harm J ^a   Spiegel, Sarah ^a   Voelkel, Norbert F ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CERAMIDE; DIHYDROCERAMIDE; FENRETINIDE; HISTONE DEACETYLASE 2; HYPOXIA INDUCIBLE FACTOR 1ALPHA; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE 2; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EMPHYSEMA; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS; LUNG ALVEOLUS CELL; LUNG PARENCHYMA; MALE; MASS SPECTROMETRY; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

ANIMALS; CASPASE 3; CERAMIDES; EMPHYSEMA; FENRETINIDE; GENE EXPRESSION REGULATION; HISTONE DEACETYLASE 2; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; LYSOPHOSPHOLIPIDS; MALE; NF-E2-RELATED FACTOR 2; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTECTIVE AGENTS; PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SPHINGOSINE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

RATTUS;

EID: 84872230128     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053927     Document Type: Article

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