Achievements and challenges in the biology of environmental effects

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue SUPPL.2, 2012, Pages 17149-17153

  Rutter, Michael ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Causal inferences; Epigenetics; Neuroplasticity; Sensitive periods

Indexed keywords

ACHIEVEMENT; CULTURAL ANTHROPOLOGY; ENVIRONMENTAL FACTOR; EPIGENETICS; GENETIC HETEROGENEITY; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; PRIORITY JOURNAL; REVIEW; ANIMAL; BRAIN; CHILD; CHILD DEVELOPMENT; EPIDEMIOLOGY; GENETIC EPIGENESIS; GROWTH, DEVELOPMENT AND AGING; HYPOTHALAMUS HYPOPHYSIS SYSTEM; INFLAMMATION; NERVE CELL PLASTICITY; PATHOPHYSIOLOGY; PHYSIOLOGICAL STRESS; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; SOCIAL ENVIRONMENT; SOCIAL STATUS;

ANIMALS; BRAIN; CAUSALITY; CHILD; CHILD DEVELOPMENT; EPIGENESIS, GENETIC; GENE-ENVIRONMENT INTERACTION; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INFLAMMATION; NEURONAL PLASTICITY; SOCIAL CONDITIONS; SOCIAL ENVIRONMENT; STRESS, PHYSIOLOGICAL;

EID: 84872227493     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1121258109     Document Type: Review

References (82)

1. Bruce MA, et al. (2009) Social environmental stressors, psychological factors, and kidney disease. J Investig Med 57:583-589.
2. Rutter M (2012) Gene-environment interdependence. Eur J Dev Psychol, 10.1080/17405629.2012.661174.
3. Plomin R, Bergeman CS (1991) The nature of nurture: Genetic influence on "environmental" measures. Behav Brain Sci 14:373-386.
4. Academy of Medical Sciences (2007) Identifying the Environmental Causes of Disease: How Should We Decide What to Believe and When to Take Action? (Academy of Medical Sciences, London).
5. Rutter M (2007) Proceeding from observed correlations to causal inference: The use of natural experiments. Perspect Psychol Sci 2:377-395.
6. Greely HT, Wagner AD (2011) Reference guide on neuroscience. Reference Manual on Scientific Evidence (National Academy Press, Washington, DC), 3rd Ed, pp 747-812.
7. Royal Society (2011) Brainwaves Module 4: Neuroscience and the Law (Royal Society, London, UK).
8. Hertzman C, Boyce T (2010) How experience gets under the skin to create gradients in developmental health. Annu Rev Public Health 31:329-347, 3p following 347.
9. Greenough WT, Volkmar FR, Juraska JM (1973) Effects of rearing complexity on dendritic branching in frontolateral and temporal cortex of the rat. Exp Neurol 41:371-378.
10. Greenough WT, Black JE, Wallace CS (1987) Experience and brain development. Child Dev 58:539-559.
11. Rosenzweig MR, Krech D, Bennett EL, Diamond MC (1962) Effects of environmental complexity and training on brain chemistry and anatomy: A replication and extension. J Comp Physiol Psychol 55:429-437.
12. Maguire EA, et al. (2000) Navigation-related structural change in the hippocampi of taxi drivers. Proc Natl Acad Sci USA 97:4398-4403. (Pubitemid 30226144)
13. Woollett K, Spiers HJ, Maguire EA (2009) Talent in the taxi: A model system for exploring expertise. Philos Trans R Soc Lond B Biol Sci 364:1407-1416.
14. Elbert T, Pantev C, Wienbruch C, Rockstroh B, Taub E (1995) Increased cortical representation of the fingers of the left hand in string players. Science 270:305-307.
15. Sluming V, Brooks J, Howard M, Downes JJ, Roberts N (2007) Broca's area supports enhanced visuospatial cognition in orchestral musicians. J Neurosci 27:3799-3806. (Pubitemid 46557679)
16. Draganski B, et al. (2004) Neuroplasticity: Changes in grey matter induced by training. Nature 427:311-312. (Pubitemid 38133650)
17. Hubel DH, Wiesel TN (2005) Brain and Visual Perception (Oxford Univ Press, Oxford).
18. Bateson P, et al. (2004) Developmental plasticity and human health. Nature 430:419-421. (Pubitemid 38987896)
19. Rutter M, O'Connor TG; English and Romanian Adoptees (ERA) Study Team (2004) Are there biological programming effects for psychological development? Findings from a study of Romanian adoptees. Dev Psychol 40:81-94. (Pubitemid 38061544)
20. Barker DJP (1999) Fetal programming and public health. Fetal Programming: Influences on Development and Disease in Later Life, eds O'Brien PMS, Wheeler T, Barker DJP (RCOG Press, London), pp 3-11.
21. Kuhl PK, et al. (1997) Cross-language analysis of phonetic units in language addressed to infants. Science 277:684-686. (Pubitemid 27373913)
22. Maye J, Werker JF, Gerken L (2002) Infant sensitivity to distributional information can affect phonetic discrimination. Cognition 82:B101-B111. (Pubitemid 34017394)
23. Bavelier D, Levi DM, Li RW, Dan Y, Hensch TK (2010) Removing brakes on adult brain plasticity: From molecular to behavioral interventions. J Neurosci 30:14964-14971.
24. Hensch TK (2005) Critical period plasticity in local cortical circuits. Nat Rev Neurosci 6:877-888.
25. Huttenlocher PR (2002) Neural Plasticity: The Effects of Environment on the Development of the Cerebral Cortex (Harvard Univ Press, Cambridge, MA).
26. Pascual-Leone A, Amedi A, Fregni F, Merabet LB (2005) The plastic human brain cortex. Annu Rev Neurosci 28:377-401. (Pubitemid 41098910)
27. Costello EJ, Compton SN, Keeler G, Angold A (2003) Relationships between poverty and psychopathology: A natural experiment. JAMA 290:2023-2029. (Pubitemid 37430585)
28. Stein ZA, Susser M, Saenger G, Marolla F (1975) Famine and Human Development: The Dutch Hunger Winter of 1944-1945 (Oxford Univ Press, New York).
29. Obel C, et al. (2011) Is maternal smoking during pregnancy a risk factor for hyperkinetic disorder? - Findings from a sibling design. Int J Epidemiol 40:338-345.
30. Thapar A, et al. (2009) Prenatal smoking may not cause ADHD: Evidence from a novel design. Biol Psychiatry 66:722-727.
31. Silberg JL, et al. (2003) Maternal smoking during pregnancy and risk to boys ' conduct disturbance: An examination of the causal hypothesis. Biol Psychiatry 53:130-135. (Pubitemid 36126475)
32. D'Onofrio BM, et al. (2008) Smoking during pregnancy and offspring externalizing problems: An exploration of genetic and environmental confounds. Dev Psychopathol 20:139-164. (Pubitemid 351166710)
33. Jaffee S R, Strait LB, Odgers C L (2012) From correlates to causes: Can quasi-experimental studies and statistical innovations bring us closer to identifying the causes of antisocial behavior? Psychol Bull 138:272-295.
34. Zink CF, et al. (2008) Know your place: Neural processing of social hierarchy in humans. Neuron 58:273-283. (Pubitemid 351545836)
35. Hariri AR, et al. (2002) Serotonin transporter genetic variation and the response of the human amygdala. Science 297:400-403. (Pubitemid 34790769)
36. Meyer-Lindenberg A, et al. (2006) Neural mechanisms of genetic risk for impulsivity and violence in humans. Proc Natl Acad Sci USA 103:6269-6274.
37. Battaglia M, Ogliari A (2005) Anxiety and panic: From human studies to animal research and back. Neurosci Biobehav Rev 29:169-179. (Pubitemid 40094586)
38. Rutter M (2006) Implications of resilience concepts for scientific understanding. Ann N Y Acad Sci 1094:1-12.
39. Rutter M Resilience: Clinical implications. J Child Psychol Psychiatry, in press.
40. Adler NE, Rehkopf DH (2008) U.S. disparities in health: Descriptions, causes, and mechanisms. Annu Rev Public Health 29:235-252. (Pubitemid 351600407)
41. Osler M, et al. (2009) Do childhood and adult socioeconomic circumstances influence health and physical function in middle-age? Soc Sci Med 68:1425-1431.
42. Marmot MG, Bosma H, Hemingway H, Brunner E, Stansfeld S (1997) Contribution of job control and other risk factors to social variations in coronary heart disease incidence. Lancet 350:235-239. (Pubitemid 27312292)
43. Kittleson MM, et al. (2006) Association of childhood socioeconomic status with subsequent coronary heart disease in physicians. Arch Intern Med 166:2356-2361. (Pubitemid 44833361)
44. Shonkoff JP, Boyce WT, McEwen BS (2009) Neuroscience, molecular biology, and the childhood roots of health disparities: Building a new framework for health promotion and disease prevention. JAMA 301:2252-2259.
45. Cohen S, et al. (2008) Objective and subjective socioeconomic status and susceptibility to the common cold. Health Psychol 27:268-274. (Pubitemid 351626287)
46. Singh-Manoux A, Marmot MG, Adler NE (2005) Does subjective social status predict health and change in health status better than objective status? Psychosom Med 67:855-861. (Pubitemid 43740098)
47. Gianaros PJ, et al. (2007) Perigenual anterior cingulate morphology covaries with perceived social standing. Soc Cogn Affect Neurosci 2:161-173. (Pubitemid 47399909)
48. Bulik CM, Prescott CA, Kendler KS (2001) Features of childhood sexual abuse and the development of psychiatric and substance use disorders. Br J Psychiatry 179:444-449. (Pubitemid 33097168)
49. Kelly Y, Sacker A, Del Bono E, Francesconi M, Marmot M (2011) What role for the home learning environment and parenting in reducing the socioeconomic gradient in child development? Findings from the Millennium Cohort Study. Arch Dis Child 96:832-837.
50. Hackman DA, Farah MJ (2009) Socioeconomic status and the developing brain. Trends Cogn Sci 13:65-73.
51. Jaenisch R, Bird A (2003) Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals. Nat Genet 33(Suppl):245-254. (Pubitemid 36278835)
52. Champagne FA (2010) Early adversity and developmental outcomes: Interaction between genetics, epigenetics, and social experiences across the life span. Perspect Psychol Sci 5:564-574.
53. Mill J, Petronis A (2007) Molecular studies of major depressive disorder: The epigenetic perspective. Mol Psychiatry 12:799-814. (Pubitemid 47347791)
54. Meaney MJ (2010) Epigenetics and the biological definition of gene x environment interactions. Child Dev 81:41-79.
55. Weaver ICG, Meaney MJ, Szyf M (2006) Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. Proc Natl Acad Sci USA 103:3480-3485. (Pubitemid 43346494)
56. Jirtle RL, Skinner MK (2007) Environmental epigenomics and disease susceptibility. Nat Rev Genet 8:253-262. (Pubitemid 46439287)
57. McGowan PO, et al. (2008) Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain. PLoS One 3:e2085.
58. McGowan PO, et al. (2009) Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci 12:342-348.
59. Essex MJ, et al. (2011) Epigenetic vestiges of early developmental adversity: Childhood stress exposure and DNA methylation in adolescence. Child Dev, 10.1111/j.1467-8624.2011.01641.
60. Heijmans BT, Mill J (2012) Commentary: The seven plagues of epigenetic epidemiology. Int J Epidemiol 41:74-78.
61. Rutter M Biomarkers: potential and challenges. BioPrediction of Bad Behavior: Scientific, Ethical and Legal Challenges, eds Singh I, Sinnott-Armstrong W, Savulescu J (Oxford Univ Press, Oxford).
62. Rutter M, Sonuga-Barke EJ (2010) Conclusions: Overview of findings from the ERA study, inferences, and research implications. Monogr Soc Res Child Dev 75(1):212-229.
63. Marshall PJ, Fox NA; Bucharest Early Intervention Project Core Group (2004) A comparison of the electroencephalogram between institutionalized and community children in Romania. J Cogn Neurosci 16:1327-1338. (Pubitemid 39410966)
64. Marshall PJ, Reeb BC, Fox NA, Nelson CA, 3rd, Zeanah CH (2008) Effects of early intervention on EEG power and coherence in previously institutionalized children in Romania. Dev Psychopathol 20:861-880. (Pubitemid 352003601)
65. McEwen BS, Gianaros PJ (2010) Central role of the brain in stress and adaptation: Links to socioeconomic status, health, and disease. Ann N Y Acad Sci 1186:190-222.
66. Gunnar M, Vazquez D (2006) Stress neurobiology and developmental psychopathology. Developmental Neuroscience, eds Cicchetti D, Cohen D (Developmental Psychopathology, New York), pp 533-577.
67. Loman MM, Gunnar MR; Early Experience, Stress, and Neurobehavioral Development Center (2010) Early experience and the development of stress reactivity and regulation in children. Neurosci Biobehav Rev 34:867-876.
68. Fisher PA, Van Ryzin MJ, Gunnar MR (2011) Mitigating HPA axis dysregulation associated with placement changes in foster care. Psychoneuroendocrinology 36:531-539.
69. Danese A, Pariante CM, Caspi A, Taylor A, Poulton R (2007) Childhood maltreatment predicts adult inflammation in a life-course study. Proc Natl Acad Sci USA 104:1319-1324. (Pubitemid 46184002)
70. Danese A, et al. (2008) Elevated inflammation levels in depressed adults with a history of childhood maltreatment. Arch Gen Psychiatry 65:409-415.
71. Petitto JM, et al. (2009) Neuroimmunology. Neurobiology of Mental Illness, eds Charney DS, Nestler EJ (Oxford Univ Press, New York), pp 215-224.
72. Rutter M (2006) Genes and Behaviour: Nature-Nurture Interplay Explained (Blackwell Scientific, Oxford).
73. Rutter M, ed (2008) Genetic effects on environmental vulnerability to disease: Novartis Foundation Symposium 293. (Wiley, Chichester, UK).
74. Dodge KA, Rutter M, eds (2011) Gene-Environment Interactions in Developmental Psychopathology (Guilford, New York).
75. Rutter M, Thapar A, Pickles A (2009) Gene-environment interactions: Biologically valid pathway or artifact? Arch Gen Psychiatry 66:1287-1289.
76. Karg K, Burmeister M, Shedden K, Sen S (2011) The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: Evidence of genetic moderation. Arch Gen Psychiatry 68:444-454.
77. Uher R, et al. (2011) Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: Replications and implications for resolving inconsistent results. J Affect Disord 135:56-65.
78. Feder A, Nestler EJ, Charney DS (2009) Psychobiology and molecular genetics of resilience. Nat Rev Neurosci 10:446-457.
79. Hackman DA, Farah MJ, Meaney MJ (2010) Socioeconomic status and the brain: Mechanistic insights from human and animal research. Nat Rev Neurosci 11:651-659.
80. Ellis BJ, Boyce WT, Belsky J, Bakermans-Kranenburg MJ, van Ijzendoorn MH (2011) Differential susceptibility to the environment: An evolutionary- neurodevelopmental theory. Dev Psychopathol 23:7-28.
81. Kendler KS, Baker JH (2007) Genetic influences on measures of the environment: A systematic review. Psychol Med 37:615-626. (Pubitemid 46511087)
82. Roth TL, Sweatt JD (2011) Annual Research Review: Epigenetic mechanisms and environmental shaping of the brain during sensitive periods of development. J Child Psychol Psychiatry 52:398-408.