Establishment of a protocol for determining gastrointestinal transit time in mice using barium and radiopaque markers

Korean Journal of Radiology

Volumn 14, Issue 1, 2013, Pages 45-50

  Myagmarjalbuu, Bolormaa ^a   Moon, Myeong Ju ^a   Heo, Suk Hee ^a   Jeong, Seo In ^a   Park, Jong Seong ^b   Jun, Jae Yeoul ^c   Jeong, Yong Yeon ^a   Kang, Heoung Keun ^a  

^a Chonnam National University Research Institute of Medical Sciences   (South Korea)

^b Chonnam National University Medical School   (South Korea)

^c Chosun University   (South Korea)

Author keywords

Experimental study; Fluoroscopy; Gastrointestinal; Loperamide; Motility disorder

Indexed keywords

BARIUM; LOPERAMIDE; METAL; SODIUM CHLORIDE;

ANAL CANAL; ANATOMICAL VARIATION; ANIMAL EXPERIMENT; ARTICLE; BIOLOGICAL MONITORING; CECUM; COLON MUCOSA; CONTROLLED STUDY; FEMALE; FLUOROSCOPY; INTESTINE TRANSIT TIME; MATERIAL COATING; MINIMALLY INVASIVE PROCEDURE; MOUSE; NONHUMAN; REPRODUCIBILITY; SMALL INTESTINE MUCOSA; STOMACH MUCOSA;

EXPERIMENTAL STUDY; FLUOROSCOPY; GASTROINTESTINAL; LOPERAMIDE; MOTILITY DISORDER;

ANALYSIS OF VARIANCE; ANIMALS; BARIUM SULFATE; CONTRAST MEDIA; FEMALE; FLUOROSCOPY; GASTROINTESTINAL TRANSIT; IRON; LOPERAMIDE; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, SCANNING; PROSTHESES AND IMPLANTS; REPRODUCIBILITY OF RESULTS; SODIUM CHLORIDE; SURFACE PROPERTIES;

EID: 84872201940     PISSN: 12296929     EISSN: None     Source Type: Journal    
DOI: 10.3348/kjr.2013.14.1.45     Document Type: Article

References (21)

1. Parkman HP, Orr WC. The gastrointestinal motility laboratory. Gastrointest Endosc Clin N Am 2009;19:171-184, viii
2. Merwid-Lad A, Trocha M, Ksiadzyna D, Sozanski T, Szelag A. Animals models for the gastrointestinal motility evaluation. Gastroenterol Pol 2009;16:201-206
3. Lester NV, Roberts GD, Newell SM, Graham JP, Hartless CS. Assessment of barium impregnated polyethylene spheres (BIPS) as a measure of solid-phase gastric emptying in normal dogs--comparison to scintigraphy. Vet Radiol Ultrasound 1999;40:465-471
4. Weber M, Stambouli F, Martin L, Dumon H, Biourge V, Nguyen P. Gastrointestinal transit of solid radiopaque markers in large and giant breed growing dogs. J Anim Physiol Anim Nutr (Berl) 2001;85:242-250
5. Chandler ML, Guilford G, Lawoko CR. Radiopaque markers to evaluate gastric emptying and small intestinal transit time in healthy cats. J Vet Intern Med 1997;11:361-364
6. Haruta S, Kawai K, Jinnouchi S, Ogawara KI, Higaki K, Tamura S, et al. Evaluation of absorption kinetics of orally administered theophylline in rats based on gastrointestinal transit monitoring by gamma scintigraphy. J Pharm Sci 2001;90:464-473
7. Marona HR, Lucchesi MB. Protocol to refine intestinal motility test in mice. Lab Anim 2004;38:257-260
8. Sparkes AH, Papasouliotis K, Barr FJ, Gruffydd-Jones TJ. Reference ranges for gastrointestinal transit of bariumimpregnated polyethylene spheres in healthy cats. J Small Anim Pract 1997;38:340-343
9. Campbell JL, Williams CV, Eisemann JH. Characterizing gastrointestinal transit time in four lemur species using barium-impregnated polyethylene spheres (BIPS). Am J Primatol 2004;64:309-321
10. Hinton JM, Lennard-Jones JE, Young AC. A ne method for studying gut transit times using radioopaque markers. Gut 1969;10:842-847
11. Mittelstadt SW, Hemenway CL, Spruell RD. Effects of fasting on evaluation of gastrointestinal transit with charcoal meal. J Pharmacol Toxicol Methods 2005;52:154-158
12. Tan-No K, Niijima F, Nakagawasai O, Sato T, Satoh S, Tadano T. Development of tolerance to the inhibitory effect of loperamide on gastrointestinal transit in mice. Eur J Pharm Sci 2003;20:357-363
13. Ogata N, Ataka K, Morino H, Shibata T. Effect of wood creosote and loperamide on propulsive motility of mouse colon and small intestine. Pharmacology 1999;59:212-220
14. Torjman MC, Joseph JI, Munsick C, Morishita M, Grunwald Z. Effects of isoflurane on gastrointestinal motility after brief exposure in rats. Int J Pharm 2005;294:65-71
15. Lee H, Dellatore SM, Miller WM, Messersmith PB. Musselinspired surface chemistry for multifunctional coatings. Science 2007;318:426-430
16. BioForum. Available at: http://www.protocol-online.org/ forums/topic/7182-mouse-liver-anatomy/
17. Saphier S, Rosner A, Brandeis R, Karton Y. Gastro intestinal tracking and gastric emptying of solid dosage forms in rats using X-ray imaging. Int J Pharm 2010;388:190-195
18. Rao SS, Camilleri M, Hasler WL, Maurer AH, Parkman HP, Saad R, et al. Evaluation of gastrointestinal transit in clinical practice: position paper of the American and European Neurogastroenterology and Motility Societies. Neurogastroenterol Motil 2011;23:8-23
19. Parrish CR. Opioid analgesics and the gastrointestinal tract. Pract Gastraenterol 2008;64:37-50
20. Szczesny G, Veihelmann A, Massberg S, Nolte D, Messmer K. Long-term anaesthesia using inhalatory isoflurane in different strains of mice-the haemodynamic effects. Lab Anim 2004;38:64-69
21. Hildebrandt IJ, Su H, Weber WA. Anesthesia and other considerations for in vivo imaging of small animals. ILAR J 2008;49:17-26