Encapsulation of proteins in hydrogel carrier systems for controlled drug delivery: Influence of network structure and drug size on release rate

Journal of Biotechnology

Volumn 163, Issue 2, 2013, Pages 243-249

  Bertz, Andreas ^a   Wöhl Bruhn, Stefanie ^a   Miethe, Sebastian ^a   Tiersch, Brigitte ^b   Koetz, Joachim ^b   Hust, Michael ^a   Bunjes, Heike ^a   Menzel, Henning ^a  

^a TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^b UNIVERSITY OF POTSDAM   (Germany)

Author keywords

Hydrogel; Hydrogel microspheres; Mesh size; Network structure; Protein delivery; Release studies

Indexed keywords

HYDROGEL MICROSPHERES; MESH SIZE; NETWORK STRUCTURES; PROTEIN DELIVERY; RELEASE STUDIES;

CONTROLLED DRUG DELIVERY; DEXTRAN; MICROSPHERES; MODEL STRUCTURES; POLYETHYLENE GLYCOLS; PORE SIZE; PROTEINS;

HYDROGELS;

DEXTRAN; FLUORESCEIN ISOTHIOCYANATE; HETASTARCH; IMMUNOGLOBULIN G; MACROGOL; METHACRYLIC ACID; MICROSPHERE; POLYMER; PROTEIN;

ARTICLE; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; DRUG DELIVERY SYSTEM; HYDRODYNAMICS; HYDROGEL; MICROENCAPSULATION; MOLECULAR MODEL; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN DEGRADATION; SCANNING ELECTRON MICROSCOPY; WETTABILITY;

DELAYED-ACTION PREPARATIONS; DEXTRANS; DRUG CARRIERS; FLUORESCEIN-5-ISOTHIOCYANATE; HUMANS; HYDROGEL; MICROSPHERES; MODELS, BIOLOGICAL; MOLECULAR WEIGHT; PARTICLE SIZE; POROSITY; PROTEINS;

EID: 84872199652     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2012.06.036     Document Type: Article

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