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Volumn 8, Issue 1, 2013, Pages

The Effect of Epstein-Barr Virus Latent Membrane Protein 2 Expression on the Kinetics of Early B Cell Infection

Author keywords

[No Author keywords available]

Indexed keywords

IMMEDIATE EARLY PROTEIN BZLF1; LATENT MEMBRANE PROTEIN 1; LATENT MEMBRANE PROTEIN 2; LATENT MEMBRANE PROTEIN 2A; LATENT MEMBRANE PROTEIN 2B; UNCLASSIFIED DRUG; VIRUS DNA;

EID: 84872184364     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054010     Document Type: Article
Times cited : (16)

References (74)
  • 1
    • 34249064632 scopus 로고    scopus 로고
    • Epstein-Barr virus
    • In: Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, et al., editors, 5th ed. Philadelphia: Lippincott, Williams & Wilkins
    • Rickinson AB, Kieff E (2007) Epstein-Barr virus. In: Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, et al., editors. Fields Virology. 5th ed. Philadelphia: Lippincott, Williams & Wilkins. 2655-2700.
    • (2007) Fields Virology , pp. 2655-2700
    • Rickinson, A.B.1    Kieff, E.2
  • 2
    • 0035496101 scopus 로고    scopus 로고
    • Epstein-Barr virus: exploiting the immune system
    • Thorley-Lawson DA, (2001) Epstein-Barr virus: exploiting the immune system. Nature reviews Immunology 1: 75-82.
    • (2001) Nature Reviews Immunology , vol.1 , pp. 75-82
    • Thorley-Lawson, D.A.1
  • 3
    • 0042467687 scopus 로고    scopus 로고
    • Epstein-Barr virus and oncogenesis: from latent genes to tumours
    • Young LS, Murray PG, (2003) Epstein-Barr virus and oncogenesis: from latent genes to tumours. Oncogene 22: 5108-5121.
    • (2003) Oncogene , vol.22 , pp. 5108-5121
    • Young, L.S.1    Murray, P.G.2
  • 4
    • 36148981135 scopus 로고    scopus 로고
    • B lymphocytes and Epstein-Barr virus: the lesson of post-transplant lymphoproliferative disorders
    • Dolcetti R, (2007) B lymphocytes and Epstein-Barr virus: the lesson of post-transplant lymphoproliferative disorders. Autoimmun Rev 7: 96-101.
    • (2007) Autoimmun Rev , vol.7 , pp. 96-101
    • Dolcetti, R.1
  • 5
    • 77950445749 scopus 로고    scopus 로고
    • EBV-associated post-transplantation B-cell lymphoproliferative disorder following allogenic stem cell transplantation for acute lymphoblastic leukaemia: tumor regression after reduction of immunosuppression--a case report
    • Krenauer A, Moll A, Ponisch W, Schmitz N, Niedobitek G, et al. (2010) EBV-associated post-transplantation B-cell lymphoproliferative disorder following allogenic stem cell transplantation for acute lymphoblastic leukaemia: tumor regression after reduction of immunosuppression--a case report. Diagn Pathol 5: 21.
    • (2010) Diagn Pathol , vol.5 , pp. 21
    • Krenauer, A.1    Moll, A.2    Ponisch, W.3    Schmitz, N.4    Niedobitek, G.5
  • 6
    • 0001403023 scopus 로고    scopus 로고
    • Molecular biology of Epstein-Barr virus
    • In: McCance D, editor, Washington DC: ASM Press
    • Longnecker R (1998) Molecular biology of Epstein-Barr virus. In: McCance D, editor. Human Tumor Viruses. Washington DC: ASM Press. 133-172.
    • (1998) Human Tumor Viruses , pp. 133-172
    • Longnecker, R.1
  • 7
    • 34249064632 scopus 로고    scopus 로고
    • Epstein-Barr virus and its replication
    • In: Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, et al., editors, 5th ed. Philadelphia: Lippincott, Williams & Wilkins
    • Kieff E, Rickinson AB (2007) Epstein-Barr virus and its replication. In: Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, et al., editors. Fields Virology. 5th ed. Philadelphia: Lippincott, Williams & Wilkins. 2603-2654.
    • (2007) Fields Virology , pp. 2603-2654
    • Kieff, E.1    Rickinson, A.B.2
  • 8
    • 0034665337 scopus 로고    scopus 로고
    • EBV persistence involves strict selection of latently infected B cells
    • Joseph AM, Babcock GJ, Thorley-Lawson DA, (2000) EBV persistence involves strict selection of latently infected B cells. Journal of immunology 165: 2975-2981.
    • (2000) Journal of Immunology , vol.165 , pp. 2975-2981
    • Joseph, A.M.1    Babcock, G.J.2    Thorley-Lawson, D.A.3
  • 10
    • 0026764617 scopus 로고
    • Epstein-Barr virus latent gene expression in uncultured peripheral blood lymphocytes
    • Qu L, Rowe DT, (1992) Epstein-Barr virus latent gene expression in uncultured peripheral blood lymphocytes. J Virol 66: 3715-3724.
    • (1992) J Virol , vol.66 , pp. 3715-3724
    • Qu, L.1    Rowe, D.T.2
  • 11
    • 33749039167 scopus 로고    scopus 로고
    • Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV's transforming genes
    • Altmann M, Pich D, Ruiss R, Wang J, Sugden B, et al. (2006) Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV's transforming genes. Proc Natl Acad Sci U S A 103: 14188-14193.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 14188-14193
    • Altmann, M.1    Pich, D.2    Ruiss, R.3    Wang, J.4    Sugden, B.5
  • 12
    • 0038243011 scopus 로고    scopus 로고
    • Latent membrane protein 1 is critical for efficient growth transformation of human B cells by epstein-barr virus
    • Dirmeier U, Neuhierl B, Kilger E, Reisbach G, Sandberg ML, et al. (2003) Latent membrane protein 1 is critical for efficient growth transformation of human B cells by epstein-barr virus. Cancer Res 63: 2982-2989.
    • (2003) Cancer Res , vol.63 , pp. 2982-2989
    • Dirmeier, U.1    Neuhierl, B.2    Kilger, E.3    Reisbach, G.4    Sandberg, M.L.5
  • 13
    • 0027449255 scopus 로고
    • Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation
    • Kaye KM, Izumi KM, Kieff E, (1993) Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation. Proc Natl Acad Sci U S A 90: 9150-9154.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 9150-9154
    • Kaye, K.M.1    Izumi, K.M.2    Kieff, E.3
  • 14
    • 0032536860 scopus 로고    scopus 로고
    • Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor
    • Kilger E, Kieser A, Baumann M, Hammerschmidt W, (1998) Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor. EMBO J 17: 1700-1709.
    • (1998) EMBO J , vol.17 , pp. 1700-1709
    • Kilger, E.1    Kieser, A.2    Baumann, M.3    Hammerschmidt, W.4
  • 15
    • 33845900225 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cells
    • Maruo S, Wu Y, Ishikawa S, Kanda T, Iwakiri D, et al. (2006) Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cells. Proc Natl Acad Sci U S A 103: 19500-19505.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 19500-19505
    • Maruo, S.1    Wu, Y.2    Ishikawa, S.3    Kanda, T.4    Iwakiri, D.5
  • 16
    • 0028233417 scopus 로고
    • EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus
    • Sinclair AJ, Palmero I, Peters G, Farrell PJ, (1994) EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus. EMBO J 13: 3321-3328.
    • (1994) EMBO J , vol.13 , pp. 3321-3328
    • Sinclair, A.J.1    Palmero, I.2    Peters, G.3    Farrell, P.J.4
  • 17
    • 79952170344 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression
    • Maruo S, Zhao B, Johannsen E, Kieff E, Zou J, et al. (2011) Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression. Proc Natl Acad Sci U S A 108: 1919-1924.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 1919-1924
    • Maruo, S.1    Zhao, B.2    Johannsen, E.3    Kieff, E.4    Zou, J.5
  • 18
    • 0016278587 scopus 로고
    • Observations on the type of infection by Epstein-Barr virus in peripheral lymphoid cells of patients with infectious mononucleosis
    • Rickinson AB, Jarvis JE, Crawford DH, Epstein MA, (1974) Observations on the type of infection by Epstein-Barr virus in peripheral lymphoid cells of patients with infectious mononucleosis. Int J Cancer 14: 704-715.
    • (1974) Int J Cancer , vol.14 , pp. 704-715
    • Rickinson, A.B.1    Jarvis, J.E.2    Crawford, D.H.3    Epstein, M.A.4
  • 19
    • 0017737483 scopus 로고
    • Comparative studies on adult donor lymphocytes infected by EB virus in vivo or in vitro: origin of transformed cells arising in co-cultures with foetal lymphocytes
    • Rickinson AB, Finerty S, Epstein MA, (1977) Comparative studies on adult donor lymphocytes infected by EB virus in vivo or in vitro: origin of transformed cells arising in co-cultures with foetal lymphocytes. Int J Cancer 19: 775-782.
    • (1977) Int J Cancer , vol.19 , pp. 775-782
    • Rickinson, A.B.1    Finerty, S.2    Epstein, M.A.3
  • 20
    • 0001658316 scopus 로고    scopus 로고
    • Epstein-Barr virus and its replication
    • In: B. Fields DKPH, editor, New York: Raven Press
    • Kieff E (1996) Epstein-Barr virus and its replication. In: B. Fields DKPH, editor. Fundamental Virology. New York: Raven Press. 1109-1162.
    • (1996) Fundamental Virology , pp. 1109-1162
    • Kieff, E.1
  • 21
    • 0024550905 scopus 로고
    • The Epstein-Barr virus (EBV) BZLF1 immediate-early gene product differentially affects latent versus productive EBV promoters
    • Kenney S, Kamine J, Holley-Guthrie E, Lin JC, Mar EC, et al. (1989) The Epstein-Barr virus (EBV) BZLF1 immediate-early gene product differentially affects latent versus productive EBV promoters. J Virol 63: 1729-1736.
    • (1989) J Virol , vol.63 , pp. 1729-1736
    • Kenney, S.1    Kamine, J.2    Holley-Guthrie, E.3    Lin, J.C.4    Mar, E.C.5
  • 22
    • 0034660443 scopus 로고    scopus 로고
    • The Epstein-Barr virus lytic program is controlled by the co-operative functions of two transactivators
    • Feederle R, Kost M, Baumann M, Janz A, Drouet E, et al. (2000) The Epstein-Barr virus lytic program is controlled by the co-operative functions of two transactivators. EMBO J 19: 3080-3089.
    • (2000) EMBO J , vol.19 , pp. 3080-3089
    • Feederle, R.1    Kost, M.2    Baumann, M.3    Janz, A.4    Drouet, E.5
  • 23
    • 1842400491 scopus 로고
    • Transfection of a rearranged viral DNA fragment, WZhet, stably converts latent Epstein-Barr viral infection to productive infection in lymphoid cells
    • Grogan E, Jenson H, Countryman J, Heston L, Gradoville L, et al. (1987) Transfection of a rearranged viral DNA fragment, WZhet, stably converts latent Epstein-Barr viral infection to productive infection in lymphoid cells. Proc Natl Acad Sci U S A 84: 1332-1336.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 1332-1336
    • Grogan, E.1    Jenson, H.2    Countryman, J.3    Heston, L.4    Gradoville, L.5
  • 24
    • 0023698910 scopus 로고
    • Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virus
    • Hammerschmidt W, Sugden B, (1988) Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virus. Cell 55: 427-433.
    • (1988) Cell , vol.55 , pp. 427-433
    • Hammerschmidt, W.1    Sugden, B.2
  • 25
    • 0022646563 scopus 로고
    • trans activation of the latent Epstein-Barr virus (EBV) genome after transfection of the EBV DNA fragment
    • Takada K, Shimizu N, Sakuma S, Ono Y, (1986) trans activation of the latent Epstein-Barr virus (EBV) genome after transfection of the EBV DNA fragment. J Virol 57: 1016-1022.
    • (1986) J Virol , vol.57 , pp. 1016-1022
    • Takada, K.1    Shimizu, N.2    Sakuma, S.3    Ono, Y.4
  • 26
    • 1642457437 scopus 로고
    • Activation of expression of latent Epstein-Barr herpesvirus after gene transfer with a small cloned subfragment of heterogeneous viral DNA
    • Countryman J, Miller G, (1985) Activation of expression of latent Epstein-Barr herpesvirus after gene transfer with a small cloned subfragment of heterogeneous viral DNA. Proc Natl Acad Sci U S A 82: 4085-4089.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 4085-4089
    • Countryman, J.1    Miller, G.2
  • 27
    • 0036091859 scopus 로고    scopus 로고
    • Protein kinase C-independent activation of the Epstein-Barr virus lytic cycle
    • Gradoville L, Kwa D, El-Guindy A, Miller G, (2002) Protein kinase C-independent activation of the Epstein-Barr virus lytic cycle. J Virol 76: 5612-5626.
    • (2002) J Virol , vol.76 , pp. 5612-5626
    • Gradoville, L.1    Kwa, D.2    El-Guindy, A.3    Miller, G.4
  • 28
    • 0023970454 scopus 로고
    • A spliced Epstein-Barr virus gene expressed in immortalized lymphocytes is created by circularization of the linear viral genome
    • Laux G, Perricaudet M, Farrell PJ, (1988) A spliced Epstein-Barr virus gene expressed in immortalized lymphocytes is created by circularization of the linear viral genome. EMBO J 7: 769-774.
    • (1988) EMBO J , vol.7 , pp. 769-774
    • Laux, G.1    Perricaudet, M.2    Farrell, P.J.3
  • 29
    • 0024535280 scopus 로고
    • Two related Epstein-Barr virus membrane proteins are encoded by separate genes
    • Sample J, Liebowitz D, Kieff E, (1989) Two related Epstein-Barr virus membrane proteins are encoded by separate genes. J Virol 63: 933-937.
    • (1989) J Virol , vol.63 , pp. 933-937
    • Sample, J.1    Liebowitz, D.2    Kieff, E.3
  • 30
    • 0027453549 scopus 로고
    • The (YXXL/I)2 signalling motif found in the cytoplasmic segments of the bovine leukaemia virus envelope protein and Epstein-Barr virus latent membrane protein 2A can elicit early and late lymphocyte activation events
    • Beaufils P, Choquet D, Mamoun RZ, Malissen B, (1993) The (YXXL/I)2 signalling motif found in the cytoplasmic segments of the bovine leukaemia virus envelope protein and Epstein-Barr virus latent membrane protein 2A can elicit early and late lymphocyte activation events. EMBO J 12: 5105-5112.
    • (1993) EMBO J , vol.12 , pp. 5105-5112
    • Beaufils, P.1    Choquet, D.2    Mamoun, R.Z.3    Malissen, B.4
  • 31
    • 0030754766 scopus 로고    scopus 로고
    • The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction
    • Fruehling S, Longnecker R, (1997) The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction. Virology 235: 241-251.
    • (1997) Virology , vol.235 , pp. 241-251
    • Fruehling, S.1    Longnecker, R.2
  • 32
    • 0033808329 scopus 로고    scopus 로고
    • The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo
    • Merchant M, Caldwell RG, Longnecker R, (2000) The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo. J Virol 74: 9115-9124.
    • (2000) J Virol , vol.74 , pp. 9115-9124
    • Merchant, M.1    Caldwell, R.G.2    Longnecker, R.3
  • 33
    • 0033981052 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A-induced B-cell survival in two unique classes of EmuLMP2A transgenic mice
    • Caldwell RG, Brown RC, Longnecker R, (2000) Epstein-Barr virus LMP2A-induced B-cell survival in two unique classes of EmuLMP2A transgenic mice. J Virol 74: 1101-1113.
    • (2000) J Virol , vol.74 , pp. 1101-1113
    • Caldwell, R.G.1    Brown, R.C.2    Longnecker, R.3
  • 34
    • 0032169313 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals
    • Caldwell RG, Wilson JB, Anderson SJ, Longnecker R, (1998) Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals. Immunity 9: 405-411.
    • (1998) Immunity , vol.9 , pp. 405-411
    • Caldwell, R.G.1    Wilson, J.B.2    Anderson, S.J.3    Longnecker, R.4
  • 35
    • 34948821852 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival
    • Mancao C, Hammerschmidt W, (2007) Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival. Blood 110: 3715-3721.
    • (2007) Blood , vol.110 , pp. 3715-3721
    • Mancao, C.1    Hammerschmidt, W.2
  • 36
    • 0028088994 scopus 로고
    • An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking
    • Miller CL, Lee JH, Kieff E, Longnecker R, (1994) An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking. Proc Natl Acad Sci U S A 91: 772-776.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 772-776
    • Miller, C.L.1    Lee, J.H.2    Kieff, E.3    Longnecker, R.4
  • 37
    • 0242363228 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 2A activates beta-catenin signaling in epithelial cells
    • Morrison JA, Klingelhutz AJ, Raab-Traub N, (2003) Epstein-Barr virus latent membrane protein 2A activates beta-catenin signaling in epithelial cells. J Virol 77: 12276-12284.
    • (2003) J Virol , vol.77 , pp. 12276-12284
    • Morrison, J.A.1    Klingelhutz, A.J.2    Raab-Traub, N.3
  • 38
    • 0037100392 scopus 로고    scopus 로고
    • The B cell antigen receptor regulates the transcriptional activator beta-catenin via protein kinase C-mediated inhibition of glycogen synthase kinase-3
    • Christian SL, Sims PV, Gold MR, (2002) The B cell antigen receptor regulates the transcriptional activator beta-catenin via protein kinase C-mediated inhibition of glycogen synthase kinase-3. Journal of immunology 169: 758-769.
    • (2002) Journal of Immunology , vol.169 , pp. 758-769
    • Christian, S.L.1    Sims, P.V.2    Gold, M.R.3
  • 39
    • 84861150772 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A signaling in statu nascendi mimics a B cell antigen receptor-like activation signal
    • Engels N, Yigit G, Emmerich CH, Czesnik D, Schild D, et al. (2012) Epstein-Barr virus LMP2A signaling in statu nascendi mimics a B cell antigen receptor-like activation signal. Cell communication and signaling: CCS 10: 9.
    • (2012) Cell Communication and Signaling: CCS , vol.10 , pp. 9
    • Engels, N.1    Yigit, G.2    Emmerich, C.H.3    Czesnik, D.4    Schild, D.5
  • 40
    • 0027537458 scopus 로고
    • The last seven transmembrane and carboxy-terminal cytoplasmic domains of Epstein-Barr virus latent membrane protein 2 (LMP2) are dispensable for lymphocyte infection and growth transformation in vitro
    • Longnecker R, Miller CL, Miao XQ, Tomkinson B, Kieff E, (1993) The last seven transmembrane and carboxy-terminal cytoplasmic domains of Epstein-Barr virus latent membrane protein 2 (LMP2) are dispensable for lymphocyte infection and growth transformation in vitro. J Virol 67: 2006-2013.
    • (1993) J Virol , vol.67 , pp. 2006-2013
    • Longnecker, R.1    Miller, C.L.2    Miao, X.Q.3    Tomkinson, B.4    Kieff, E.5
  • 41
    • 0027236266 scopus 로고
    • Deletion of DNA encoding the first five transmembrane domains of Epstein-Barr virus latent membrane proteins 2A and 2B
    • Longnecker R, Miller CL, Tomkinson B, Miao XQ, Kieff E, (1993) Deletion of DNA encoding the first five transmembrane domains of Epstein-Barr virus latent membrane proteins 2A and 2B. J Virol 67: 5068-5074.
    • (1993) J Virol , vol.67 , pp. 5068-5074
    • Longnecker, R.1    Miller, C.L.2    Tomkinson, B.3    Miao, X.Q.4    Kieff, E.5
  • 42
    • 0032771587 scopus 로고    scopus 로고
    • Epstein-Barr virus lacking latent membrane protein 2 immortalizes B cells with efficiency indistinguishable from that of wild-type virus
    • Speck P, Kline KA, Cheresh P, Longnecker R, (1999) Epstein-Barr virus lacking latent membrane protein 2 immortalizes B cells with efficiency indistinguishable from that of wild-type virus. J Gen Virol 80 (Pt 8): 2193-2203.
    • (1999) J Gen Virol , vol.80 , Issue.Pt 8 , pp. 2193-2203
    • Speck, P.1    Kline, K.A.2    Cheresh, P.3    Longnecker, R.4
  • 43
    • 0029802277 scopus 로고    scopus 로고
    • The latent membrane protein 2 gene of Epstein-Barr virus is important for efficient B cell immortalization
    • Brielmeier M, Mautner J, Laux G, Hammerschmidt W, (1996) The latent membrane protein 2 gene of Epstein-Barr virus is important for efficient B cell immortalization. J Gen Virol 77 (Pt 11): 2807-2818.
    • (1996) J Gen Virol , vol.77 , Issue.Pt 11 , pp. 2807-2818
    • Brielmeier, M.1    Mautner, J.2    Laux, G.3    Hammerschmidt, W.4
  • 44
    • 0033756107 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A transforms epithelial cells, inhibits cell differentiation, and activates Akt
    • Scholle F, Bendt KM, Raab-Traub N, (2000) Epstein-Barr virus LMP2A transforms epithelial cells, inhibits cell differentiation, and activates Akt. J Virol 74: 10681-10689.
    • (2000) J Virol , vol.74 , pp. 10681-10689
    • Scholle, F.1    Bendt, K.M.2    Raab-Traub, N.3
  • 45
    • 0036256243 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 2B (LMP2B) co-localizes with LMP2A in perinuclear regions in transiently transfected cells
    • Lynch DT, Zimmerman JS, Rowe DT, (2002) Epstein-Barr virus latent membrane protein 2B (LMP2B) co-localizes with LMP2A in perinuclear regions in transiently transfected cells. J Gen Virol 83: 1025-1035.
    • (2002) J Gen Virol , vol.83 , pp. 1025-1035
    • Lynch, D.T.1    Zimmerman, J.S.2    Rowe, D.T.3
  • 47
    • 13744255187 scopus 로고    scopus 로고
    • The Epstein-Barr virus-encoded LMP2A and LMP2B proteins promote epithelial cell spreading and motility
    • Allen MD, Young LS, Dawson CW, (2005) The Epstein-Barr virus-encoded LMP2A and LMP2B proteins promote epithelial cell spreading and motility. J Virol 79: 1789-1802.
    • (2005) J Virol , vol.79 , pp. 1789-1802
    • Allen, M.D.1    Young, L.S.2    Dawson, C.W.3
  • 48
    • 38849162203 scopus 로고    scopus 로고
    • Latent membrane protein 2B regulates susceptibility to induction of lytic Epstein-Barr virus infection
    • Rechsteiner MP, Berger C, Zauner L, Sigrist JA, Weber M, et al. (2008) Latent membrane protein 2B regulates susceptibility to induction of lytic Epstein-Barr virus infection. J Virol 82: 1739-1747.
    • (2008) J Virol , vol.82 , pp. 1739-1747
    • Rechsteiner, M.P.1    Berger, C.2    Zauner, L.3    Sigrist, J.A.4    Weber, M.5
  • 49
    • 33845729873 scopus 로고    scopus 로고
    • Epstein-barr virus latent membrane protein 2B (LMP2B) modulates LMP2A activity
    • Rovedo M, Longnecker R, (2007) Epstein-barr virus latent membrane protein 2B (LMP2B) modulates LMP2A activity. J Virol 81: 84-94.
    • (2007) J Virol , vol.81 , pp. 84-94
    • Rovedo, M.1    Longnecker, R.2
  • 51
    • 29144463656 scopus 로고    scopus 로고
    • Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosis
    • Altmann M, Hammerschmidt W, (2005) Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosis. PLoS Biol 3: e404.
    • (2005) PLoS Biol , vol.3
    • Altmann, M.1    Hammerschmidt, W.2
  • 52
    • 78649746843 scopus 로고    scopus 로고
    • Extensive co-operation between the Epstein-Barr virus EBNA3 proteins in the manipulation of host gene expression and epigenetic chromatin modification
    • White RE, Groves IJ, Turro E, Yee J, Kremmer E, et al. (2010) Extensive co-operation between the Epstein-Barr virus EBNA3 proteins in the manipulation of host gene expression and epigenetic chromatin modification. PloS one 5: e13979.
    • (2010) PloS One , vol.5
    • White, R.E.1    Groves, I.J.2    Turro, E.3    Yee, J.4    Kremmer, E.5
  • 53
    • 79958001492 scopus 로고    scopus 로고
    • CD300a is expressed on human B cells, modulates BCR-mediated signaling, and its expression is down-regulated in HIV infection
    • Silva R, Moir S, Kardava L, Debell K, Simhadri VR, et al. (2011) CD300a is expressed on human B cells, modulates BCR-mediated signaling, and its expression is down-regulated in HIV infection. Blood 117: 5870-5880.
    • (2011) Blood , vol.117 , pp. 5870-5880
    • Silva, R.1    Moir, S.2    Kardava, L.3    Debell, K.4    Simhadri, V.R.5
  • 54
    • 79960011154 scopus 로고    scopus 로고
    • Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors
    • Kardava L, Moir S, Wang W, Ho J, Buckner CM, et al. (2011) Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors. J Clin Invest 121: 2614-2624.
    • (2011) J Clin Invest , vol.121 , pp. 2614-2624
    • Kardava, L.1    Moir, S.2    Wang, W.3    Ho, J.4    Buckner, C.M.5
  • 55
    • 0037069336 scopus 로고    scopus 로고
    • Glycoprotein gp110 of Epstein-Barr virus determines viral tropism and efficiency of infection
    • Neuhierl B, Feederle R, Hammerschmidt W, Delecluse HJ, (2002) Glycoprotein gp110 of Epstein-Barr virus determines viral tropism and efficiency of infection. Proc Natl Acad Sci U S A 99: 15036-15041.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 15036-15041
    • Neuhierl, B.1    Feederle, R.2    Hammerschmidt, W.3    Delecluse, H.J.4
  • 56
    • 77649188072 scopus 로고    scopus 로고
    • Cellular factors associated with latency and spontaneous Epstein-Barr virus reactivation in B-lymphoblastoid cell lines
    • Davies ML, Xu S, Lyons-Weiler J, Rosendorff A, Webber SA, et al. (2010) Cellular factors associated with latency and spontaneous Epstein-Barr virus reactivation in B-lymphoblastoid cell lines. Virology 400: 53-67.
    • (2010) Virology , vol.400 , pp. 53-67
    • Davies, M.L.1    Xu, S.2    Lyons-Weiler, J.3    Rosendorff, A.4    Webber, S.A.5
  • 57
    • 70349694198 scopus 로고    scopus 로고
    • Early events associated with infection of Epstein-Barr virus infection of primary B-cells
    • Halder S, Murakami M, Verma SC, Kumar P, Yi F, et al. (2009) Early events associated with infection of Epstein-Barr virus infection of primary B-cells. PloS one 4: e7214.
    • (2009) PloS One , vol.4
    • Halder, S.1    Murakami, M.2    Verma, S.C.3    Kumar, P.4    Yi, F.5
  • 59
    • 0342711256 scopus 로고    scopus 로고
    • In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
    • Lam KP, Kuhn R, Rajewsky K, (1997) In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 90: 1073-1083.
    • (1997) Cell , vol.90 , pp. 1073-1083
    • Lam, K.P.1    Kuhn, R.2    Rajewsky, K.3
  • 60
    • 3242715050 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A: regulating cellular ubiquitination processes for maintenance of viral latency?
    • Portis T, Ikeda M, Longnecker R, (2004) Epstein-Barr virus LMP2A: regulating cellular ubiquitination processes for maintenance of viral latency? Trends in immunology 25: 422-426.
    • (2004) Trends in Immunology , vol.25 , pp. 422-426
    • Portis, T.1    Ikeda, M.2    Longnecker, R.3
  • 61
    • 76249132533 scopus 로고    scopus 로고
    • AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome
    • Kalla M, Schmeinck A, Bergbauer M, Pich D, Hammerschmidt W, (2010) AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome. Proc Natl Acad Sci U S A 107: 850-855.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 850-855
    • Kalla, M.1    Schmeinck, A.2    Bergbauer, M.3    Pich, D.4    Hammerschmidt, W.5
  • 62
    • 78650217703 scopus 로고    scopus 로고
    • An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells
    • Nikitin PA, Yan CM, Forte E, Bocedi A, Tourigny JP, et al. (2010) An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells. Cell host & microbe 8: 510-522.
    • (2010) Cell Host & Microbe , vol.8 , pp. 510-522
    • Nikitin, P.A.1    Yan, C.M.2    Forte, E.3    Bocedi, A.4    Tourigny, J.P.5
  • 63
    • 0021351866 scopus 로고
    • Cross-linking of cell surface immunoglobulins induces Epstein-Barr virus in Burkitt lymphoma lines
    • Takada K, (1984) Cross-linking of cell surface immunoglobulins induces Epstein-Barr virus in Burkitt lymphoma lines. Int J Cancer 33: 27-32.
    • (1984) Int J Cancer , vol.33 , pp. 27-32
    • Takada, K.1
  • 64
    • 0028970289 scopus 로고
    • Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases
    • Miller CL, Burkhardt AL, Lee JH, Stealey B, Longnecker R, et al. (1995) Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases. Immunity 2: 155-166.
    • (1995) Immunity , vol.2 , pp. 155-166
    • Miller, C.L.1    Burkhardt, A.L.2    Lee, J.H.3    Stealey, B.4    Longnecker, R.5
  • 65
    • 9644279753 scopus 로고    scopus 로고
    • Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway
    • Portis T, Longnecker R, (2004) Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway. Oncogene 23: 8619-8628.
    • (2004) Oncogene , vol.23 , pp. 8619-8628
    • Portis, T.1    Longnecker, R.2
  • 66
    • 0028105796 scopus 로고
    • Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes
    • Merino R, Ding L, Veis DJ, Korsmeyer SJ, Nunez G, (1994) Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes. EMBO J 13: 683-691.
    • (1994) EMBO J , vol.13 , pp. 683-691
    • Merino, R.1    Ding, L.2    Veis, D.J.3    Korsmeyer, S.J.4    Nunez, G.5
  • 67
    • 0029670773 scopus 로고    scopus 로고
    • bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice
    • Grillot DA, Merino R, Pena JC, Fanslow WC, Finkelman FD, et al. (1996) bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice. J Exp Med 183: 381-391.
    • (1996) J Exp Med , vol.183 , pp. 381-391
    • Grillot, D.A.1    Merino, R.2    Pena, J.C.3    Fanslow, W.C.4    Finkelman, F.D.5
  • 69
    • 0025342480 scopus 로고
    • Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23
    • Wang F, Gregory C, Sample C, Rowe M, Liebowitz D, et al. (1990) Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23. J Virol 64: 2309-2318.
    • (1990) J Virol , vol.64 , pp. 2309-2318
    • Wang, F.1    Gregory, C.2    Sample, C.3    Rowe, M.4    Liebowitz, D.5
  • 70
    • 0019833474 scopus 로고
    • Identification of antigenic determinants unique to the surfaces of cells transformed by Epstein-Barr virus
    • Kintner C, Sugden B, (1981) Identification of antigenic determinants unique to the surfaces of cells transformed by Epstein-Barr virus. Nature 294: 458-460.
    • (1981) Nature , vol.294 , pp. 458-460
    • Kintner, C.1    Sugden, B.2
  • 71
    • 0022455310 scopus 로고
    • Identification of a cell-surface glycoprotein mediating cell adhesion in EBV-immortalized normal B cells
    • Patarroyo M, Beatty PG, Nilsson K, Gahmberg CG, (1986) Identification of a cell-surface glycoprotein mediating cell adhesion in EBV-immortalized normal B cells. Int J Cancer 38: 539-547.
    • (1986) Int J Cancer , vol.38 , pp. 539-547
    • Patarroyo, M.1    Beatty, P.G.2    Nilsson, K.3    Gahmberg, C.G.4
  • 72
    • 0020063727 scopus 로고
    • Monoclonal antibodies to Epstein-Barr virus-induced, transformation-associated cell surface antigens: binding patterns and effect upon virus-specific T-cell cytotoxicity
    • Rowe M, Hildreth JE, Rickinson AB, Epstein MA, (1982) Monoclonal antibodies to Epstein-Barr virus-induced, transformation-associated cell surface antigens: binding patterns and effect upon virus-specific T-cell cytotoxicity. Int J Cancer 29: 373-381.
    • (1982) Int J Cancer , vol.29 , pp. 373-381
    • Rowe, M.1    Hildreth, J.E.2    Rickinson, A.B.3    Epstein, M.A.4
  • 73
    • 0021812445 scopus 로고
    • Early events in Epstein-Barr virus infection provide a model for B cell activation
    • Thorley-Lawson DA, Mann KP, (1985) Early events in Epstein-Barr virus infection provide a model for B cell activation. J Exp Med 162: 45-59.
    • (1985) J Exp Med , vol.162 , pp. 45-59
    • Thorley-Lawson, D.A.1    Mann, K.P.2
  • 74
    • 0027211796 scopus 로고
    • Epstein-Barr virus latent membrane protein 2A blocks calcium mobilization in B lymphocytes
    • Miller CL, Longnecker R, Kieff E, (1993) Epstein-Barr virus latent membrane protein 2A blocks calcium mobilization in B lymphocytes. J Virol 67: 3087-3094.
    • (1993) J Virol , vol.67 , pp. 3087-3094
    • Miller, C.L.1    Longnecker, R.2    Kieff, E.3


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