-
1
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975;256:495-7
-
(1975)
Nature
, vol.256
, pp. 495-7
-
-
Kohler, G.1
Milstein, C.2
-
2
-
-
0022374645
-
Presence of epidermal growth factor receptor as an indicator of poor prognosis in patients with breast cancer
-
Sainsbury JR, Malcolm AJ, Appleton DR. Presence of epidermal growth factor receptor as an indicator of poor prognosis in patients with breast cancer. J Clin Pathol 1985;38(11):1225-8 (Pubitemid 16215034)
-
(1985)
Journal of Clinical Pathology
, vol.38
, Issue.11
, pp. 1225-1228
-
-
Sainsbury, J.R.C.1
Malcolm, A.J.2
Appleton, D.R.3
-
3
-
-
0029441596
-
Association of epidermal growth factor-related peptides and type i receptor tyrosine kinase receptors with prognosis of human colorectal carcinomas
-
Saeki T, Salomon DS, Johnson GR. Association of epidermal growth factor-related peptides and type I receptor tyrosine kinase receptors with prognosis of human colorectal carcinomas. Jpn J Clin Oncol 1995;25(6):240-9
-
(1995)
Jpn J Clin Oncol
, vol.25
, Issue.6
, pp. 240-9
-
-
Saeki, T.1
Salomon, D.S.2
Johnson, G.R.3
-
4
-
-
32044464123
-
Epidermal growth factor receptor (EGFR) signaling in cancer
-
DOI 10.1016/j.gene.2005.10.018, PII S0378111905006347
-
Normanno N, De Luca A, Bianco C. Epidermal growth factor receptor (EGFR) signaling in cancer. Gene, 2006;366(1):2-16 (Pubitemid 43199589)
-
(2006)
Gene
, vol.366
, Issue.1
, pp. 2-16
-
-
Normanno, N.1
De Luca, A.2
Bianco, C.3
Strizzi, L.4
Mancino, M.5
Maiello, M.R.6
Carotenuto, A.7
De Feo, G.8
Caponigro, F.9
Salomon, D.S.10
-
5
-
-
0028819660
-
Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model
-
Goldstein NI, Prewett M, Zuklys K, et al. Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model. Clin Cancer Res 1995;1(11):1311-18
-
(1995)
Clin Cancer Res
, vol.1
, Issue.11
, pp. 1311-18
-
-
Goldstein, N.I.1
Prewett, M.2
Zuklys, K.3
-
6
-
-
0028969852
-
Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin
-
Wu X, Fan Z, Masui H, et al. Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin. J Clin Invest 1995;95(4):1897-904
-
(1995)
J Clin Invest
, vol.95
, Issue.4
, pp. 1897-904
-
-
Wu, X.1
Fan, Z.2
Masui, H.3
-
7
-
-
0027290650
-
Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies
-
Baselga J, Norton L, Masui H, Pandiella A. Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies. J Natl Cancer Inst 1993;85(16):1327-33 (Pubitemid 23249725)
-
(1993)
Journal of the National Cancer Institute
, vol.85
, Issue.16
, pp. 1327-1333
-
-
Baselga, J.1
Norton, L.2
Masui, H.3
Pandiella, A.4
Coplan, K.5
Miller Jr., W.H.6
Mendelsohn, J.7
-
8
-
-
0027428571
-
Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well established A431 cell xenografts
-
Fan Z, Baselga J, Masui H, Mendelsohn J. Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well established A431 cell xenografts. Cancer Res 1993;53(19):4637-42 (Pubitemid 23304392)
-
(1993)
Cancer Research
, vol.53
, Issue.18
, pp. 4637-4642
-
-
Fan, Z.1
Baselga, J.2
Masui, H.3
Mendelsohn, J.4
-
9
-
-
0030959114
-
A subclass of tumor-inhibitory monoclonal antibodies to ErbB-2/HER2 blocks crosstalk with growth factor receptors
-
Klapper LN, Vaisman N, Hurwitz E, et al. A subclass of tumor-inhibitory monoclonal antibodies to ErbB-2/HER2 blocks crosstalk with growth factor receptors. Oncogene 1997;14(17):2099-109 . This provides the evidence for mechanism of action of trastuzumab by blocking interaction between various HER receptors. (Pubitemid 27237013)
-
(1997)
Oncogene
, vol.14
, Issue.17
, pp. 2099-2109
-
-
Klapper, L.N.1
Vaisman, N.2
Hurwitz, E.3
Pinkas-Kramarski, R.4
Yarden, Y.5
Sela, M.6
-
10
-
-
0033996361
-
ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: Receptor overexpression does not determine growth dependency
-
DOI 10.1128/MCB.20.9.3210-3223.2000
-
Lane HA, Beuvink I, Motoyama AB, et al. ErbB2 potentiates breast tumor proliferation through modulation of p27 (Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency. Mol Cell Biol 2000;20(9):3210-23 (Pubitemid 30215033)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.9
, pp. 3210-3223
-
-
Lane, H.A.1
Beuvink, I.2
Motoyama, A.B.3
Daly, J.M.4
Neve, R.M.5
Hynes, N.E.6
-
11
-
-
33747880652
-
Ex vivo-activated human macrophages kill chronic lymphocytic leukemia cells in the presence of rituximab: Mechanism of antibody-dependent cellular cytotoxicity and impact of human serum
-
DOI 10.1097/01.cji.0000203081.43235.d7, PII 0000237120060700000005
-
Lefebvre ML, Krause SW, Salcedo M, Nardin A. Ex vivo-Activated human macrophages kill chronic lymphocytic leukemia cells in the presence of rituximab: mechanism of antibody-dependent cellular cytotoxicity and impact of human serum. J Immunother 2006;29(4):388-97 (Pubitemid 44288951)
-
(2006)
Journal of Immunotherapy
, vol.29
, Issue.4
, pp. 388-397
-
-
Lefebvre, M.-L.1
Krause, S.W.2
Salcedo, M.3
Nardin, A.4
-
12
-
-
3042743884
-
Rituximab-dependent cytotoxicity by natural killer cells: Influence of FCGR3A polymorphism on the concentration-effect relationship
-
DOI 10.1158/0008-5472.CAN-03-2862
-
Dall'Ozzo S, Tartas S, Paintaud G, et al. Rituximab-dependent cytotoxicity by natural killer cells: influence of FCGR3A polymorphism on the concentration-effect relationship. Cancer Res 2004;64(13):4664-9 (Pubitemid 38856941)
-
(2004)
Cancer Research
, vol.64
, Issue.13
, pp. 4664-4669
-
-
Dall'Ozzo, S.1
Tartas, S.2
Paintaud, G.3
Cartron, G.4
Colombat, P.5
Bardos, P.6
Watier, H.7
Thibault, G.8
-
13
-
-
0347447283
-
Neutrophils Contribute to the Biological Antitumor Activity of Rituximab in a Non-Hodgkin's Lymphoma Severe Combined Immunodeficiency Mouse Model
-
Hernandez-Ilizaliturri FJ, Jupudy V, Ostberg J, et al. Neutrophils contribute to the biological antitumor activity of rituximab in a non-Hodgkin's lymphoma severe combined immunodeficiency mouse model. Clin Cancer Res 2003;9(16 Pt 1):5866-73 (Pubitemid 38018069)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.16
, pp. 5866-5873
-
-
Hernandez-Ilizaliturri, F.J.1
Jupudy, V.2
Ostberg, J.3
Oflazoglu, E.4
Huberman, A.5
Repasky, E.6
Czuczman, M.S.7
-
14
-
-
0034076307
-
Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
-
DOI 10.1038/74704
-
Clynes RA, Towers TL, Presta LG. Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets. Nat Med 2000;6(4):443-6 (Pubitemid 30208162)
-
(2000)
Nature Medicine
, vol.6
, Issue.4
, pp. 443-446
-
-
Clynes, R.A.1
Towers, T.L.2
Presta, L.G.3
Ravetch, J.V.4
-
15
-
-
0030611643
-
FcγRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell FCγRIIIa, independently of the FCγRIIIa-48L/R/H phenotype
-
Koene HR, Kleijer M, Algra J. Fc gammaRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell Fc gammaRIIIa, independently of the Fc gammaRIIIa-48L/R/H phenotype. Blood 1997;90(3):1109-14 Pre-clinical data showing influence of FcGamma receptor polymorphisms on antibody binding to the targets. (Pubitemid 27314146)
-
(1997)
Blood
, vol.90
, Issue.3
, pp. 1109-1114
-
-
Koene, H.R.1
Kleijer, M.2
Algra, J.3
Roos, D.4
Von Dem Borne, A.E.G.K.5
De Haas, M.6
-
16
-
-
0036464719
-
Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcγrIIIa gene
-
DOI 10.1182/blood.V99.3.754
-
Cartron G, Dacheux L, Salles G. Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene. Blood 2002;99(3):754-8 (Pubitemid 34525533)
-
(2002)
Blood
, vol.99
, Issue.3
, pp. 754-758
-
-
Cartron, G.1
Dacheux, L.2
Salles, G.3
Solal-Celigny, P.4
Bardos, P.5
Colombat, P.6
Watier, H.7
-
17
-
-
84864131126
-
Fc gamma receptor polymorphisms as predictive markers of cetuximab efficacy in epidermal growth factor receptor downstream-mutated metastatic colorectal cancer
-
Rodriguez J, Zarate R, Bandres E. Fc gamma receptor polymorphisms as predictive markers of Cetuximab efficacy in epidermal growth factor receptor downstream-mutated metastatic colorectal cancer. Eur J Cancer 2012;48(12):1774-80
-
(2012)
Eur J Cancer
, vol.48
, Issue.12
, pp. 1774-80
-
-
Rodriguez, J.1
Zarate, R.2
Bandres, E.3
-
18
-
-
79958041608
-
Bispecific antibodies engage t cells for antitumor immunotherapy
-
Choi BD, Cai M, Bigner DD. Bispecific antibodies engage T cells for antitumor immunotherapy. Expert Opin Biol Ther 2011;11(7):843-53
-
(2011)
Expert Opin Biol Ther
, vol.11
, Issue.7
, pp. 843-53
-
-
Choi, B.D.1
Cai, M.2
Bigner, D.D.3
-
20
-
-
79959312575
-
Targeted therapy with the t-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in b-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival
-
Topp MS, Kufer P, Gokbuget N. Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival. J Clin Oncol 2011;29(18):2493-8
-
(2011)
J Clin Oncol
, vol.29
, Issue.18
, pp. 2493-8
-
-
Topp, M.S.1
Kufer, P.2
Gokbuget, N.3
-
21
-
-
0031919928
-
Therapeutic inhibition of the complement system
-
Makrides SC. Therapeutic inhibition of the complement system. Pharmacol Rev 1998 Mar;50(1):59-87 (Pubitemid 28158842)
-
(1998)
Pharmacological Reviews
, vol.50
, Issue.1
, pp. 59-87
-
-
Makrides, S.C.1
-
22
-
-
0042346042
-
Complement activation determines the therapeutic activity of rituximab in vivo
-
Di Gaetano N, Cittera E, Nota R, et al. Complement activation determines the therapeutic activity of rituximab in vivo. J Immunol 2003;171(3):1581-7 (Pubitemid 36900094)
-
(2003)
Journal of Immunology
, vol.171
, Issue.3
, pp. 1581-1587
-
-
Di Gaetano, N.1
Cittera, E.2
Nota, R.3
Vecchi, A.4
Grieco, V.5
Scanziani, E.6
Botto, M.7
Introna, M.8
Golay, J.9
-
23
-
-
33644501166
-
The role of complement in the therapeutic activity of rituximab in a murine b lymphoma model homing in lymph nodes
-
Golay J, Cittera E, Di Gaetano N, et al. The role of complement in the therapeutic activity of rituximab in a murine B lymphoma model homing in lymph nodes. Haematologica 2006;91(2):176-83
-
(2006)
Haematologica
, vol.91
, Issue.2
, pp. 176-83
-
-
Golay, J.1
Cittera, E.2
Di Gaetano, N.3
-
24
-
-
1842507429
-
Alemtuzumab (CAMPATH 1H) does not kill chronic lymphocytic leukemia cells in serum free medium
-
DOI 10.1016/j.leukres.2003.09.011, PII S0145212603003187
-
Zent CS, Chen JB, Kurten RC. Alemtuzumab (CAMPATH 1H) does not kill chronic lymphocytic leukemia cells in serum free medium. Leuk Res 2004;28(5):495-507 (Pubitemid 38453062)
-
(2004)
Leukemia Research
, vol.28
, Issue.5
, pp. 495-507
-
-
Zent, C.S.1
Chen, J.B.2
Kurten, R.C.3
Kaushal, G.P.4
Lacy, H.M.5
Schichman, S.A.6
-
25
-
-
0034999619
-
Tumor cell expression of CD59 is associated with resistance to CD20 serotherapy in patients with B-cell malignancies
-
DOI 10.1097/00002371-200105000-00011
-
Treon SP, Mitsiades C, Mitsiades N, et al. Tumor cell expression of CD59 is associated with resistance to CD20 serotherapy in patients with B-cell malignancies. J Immunother 2001;24(3):263-71 (Pubitemid 32479718)
-
(2001)
Journal of Immunotherapy
, vol.24
, Issue.3
, pp. 263-271
-
-
Treon, S.P.1
Mitsiades, C.2
Mitsiades, N.3
Young, G.4
Doss, D.5
Schlossman, R.6
Anderson, K.C.7
-
26
-
-
0035676926
-
Complement activation plays a key role in the side-effects of rituximab treatment
-
DOI 10.1046/j.1365-2141.2001.03166.x
-
Van der Kolk LE, Grillo-Lopez AJ, Baars JW, et al. Complement activation plays a key role in the side-effects of rituximab treatment. Br J Haematol 2001;115(4):807-11 Provides mechanism of action of side effects of rituximab. (Pubitemid 34042897)
-
(2001)
British Journal of Haematology
, vol.115
, Issue.4
, pp. 807-811
-
-
Van Der Kolk, L.E.1
Grillo-Lopez, A.J.2
Baars, J.W.3
Hack, C.E.4
Van Oers, M.H.J.5
-
27
-
-
14644440555
-
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
-
DOI 10.1200/JCO.2005.06.081
-
Hicklin DJ, Ellis LM. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 2005;23(5):1011-27 (Pubitemid 46202320)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.5
, pp. 1011-1027
-
-
Hicklin, D.J.1
Ellis, L.M.2
-
28
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
DOI 10.1016/S0092-8674(00)80108-7
-
Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996;86(3):353-64 (Pubitemid 26272076)
-
(1996)
Cell
, vol.86
, Issue.3
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
29
-
-
0029816983
-
Complete inhibition of angiogenesis and growth of microtumors by anti- vascular endothelial growth factor neutralizing antibody: Novel concepts of angiostatic therapy from intravital videomicroscopy
-
Borgstrom P, Hillan KJ, Sriramarao P, Ferrara N. Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: novel concepts of angiostatic therapy from intravital videomicroscopy. Cancer Res 1996;56(17):4032-9 (Pubitemid 26284756)
-
(1996)
Cancer Research
, vol.56
, Issue.17
, pp. 4032-4039
-
-
Borgstrom, P.1
Hillan, K.J.2
Sriramarao, P.3
Ferrara, N.4
-
30
-
-
11144354392
-
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
-
DOI 10.1038/nm988
-
Willett CG, Boucher Y, di Tomaso E. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat Med 2004;10(2):145-7 (Pubitemid 38524883)
-
(2004)
Nature Medicine
, vol.10
, Issue.2
, pp. 145-147
-
-
Willett, C.G.1
Boucher, Y.2
Di Tomaso, E.3
Duda, D.G.4
Munn, L.L.5
Tong, R.T.6
Chung, D.C.7
Sahani, D.V.8
Kalva, S.P.9
Kozin, S.V.10
Mino, M.11
Cohen, K.S.12
Scadden, D.T.13
Hartford, A.C.14
Fischman, A.J.15
Clark, J.W.16
Ryan, D.P.17
Zhu, A.X.18
Blaszkowsky, L.S.19
Chen, H.X.20
Shellito, P.C.21
Lauwers, G.Y.22
Jain, R.K.23
more..
-
31
-
-
19644389279
-
Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation
-
DOI 10.1158/0008-5472.CAN-04-3589
-
Hodge DR, Peng B, Cherry JC. Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation. Cancer Res 2005;65:4673-82 (Pubitemid 40740803)
-
(2005)
Cancer Research
, vol.65
, Issue.11
, pp. 4673-4682
-
-
Hodge, D.R.1
Peng, B.2
Cherry, J.C.3
Hurt, E.M.4
Fox, S.D.5
Kelley, J.A.6
Munroe, D.J.7
Farrar, W.L.8
-
32
-
-
0028921477
-
Interleukin-6 in human multiple myeloma
-
Klein B, Zhang XG, Lu ZY, Bataille R. Interleukin-6 in human multiple myeloma. Blood 1995;85(4):863-72
-
(1995)
Blood
, vol.85
, Issue.4
, pp. 863-72
-
-
Klein, B.1
Zhang, X.G.2
Lu, Z.Y.3
Bataille, R.4
-
33
-
-
0142250392
-
Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: A review of the rationale and clinical evidence
-
Trikha M, Corringham R, Klein B, Rossi JF. Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence. Clin Cancer Res 2003;9(13):4653-64
-
(2003)
Clin Cancer Res
, vol.9
, Issue.13
, pp. 4653-64
-
-
Trikha, M.1
Corringham, R.2
Klein, B.3
Rossi, J.F.4
-
34
-
-
77957995258
-
A phase iii study of siltuximab (cnto 328) an anti-interleukin-6 monoclonal antibody, in metastatic renal cell cancer
-
Rossi JF, Negrier S, James ND. A phase I/II study of siltuximab (CNTO 328), an anti-interleukin-6 monoclonal antibody, in metastatic renal cell cancer. Br J Cancer 2010;103(8):1154-62
-
(2010)
Br J Cancer
, vol.103
, Issue.8
, pp. 1154-1162
-
-
Rossi, J.F.1
Negrier, S.2
James, N.D.3
-
35
-
-
80052855899
-
Interleukin-6 as a therapeutic target in human ovarian cancer
-
Coward J, Kulbe H, Chakravarty P. Interleukin-6 as a therapeutic target in human ovarian cancer. Clin Cancer Res 2011;17(18):6083-96
-
(2011)
Clin Cancer Res
, vol.17
, Issue.18
, pp. 6083-6096
-
-
Coward, J.1
Kulbe, H.2
Chakravarty, P.3
-
36
-
-
79951556761
-
Blockade of interleukin-6 signalling with siltuximab enhances melphalan cytotoxicity in preclinical models of multiple myeloma
-
Hunsucker SA, Magarotto V, Kuhn DJ. Blockade of interleukin-6 signalling with siltuximab enhances melphalan cytotoxicity in preclinical models of multiple myeloma. Br J Haematol 2011;152:579-92
-
(2011)
Br J Haematol
, vol.152
, pp. 579-592
-
-
Hunsucker, S.A.1
Magarotto, V.2
Kuhn, D.J.3
-
37
-
-
56449129810
-
Targeting her2-positive breast cancer with trastuzumab-dm1, an antibody-cytotoxic drug conjugate
-
Lewis Phillips GD, Li G, Dugger DL. Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate. Cancer Res 2008;68(22):9280-90
-
(2008)
Cancer Res
, vol.68
, Issue.22
, pp. 9280-90
-
-
Lewis Phillips, G.D.1
Li, G.2
Dugger, D.L.3
-
38
-
-
80055002179
-
Targeted drug delivery using immunoconjugates: Principles and applications
-
Pasquetto MV, Vecchia L, Covini D. Targeted drug delivery using immunoconjugates: principles and applications. J Immunother 2011;34(9):611-28
-
(2011)
J Immunother
, vol.34
, Issue.9
, pp. 611-28
-
-
Pasquetto, M.V.1
Vecchia, L.2
Covini, D.3
-
39
-
-
79960356302
-
Investigational antibody drug conjugates for solid tumors
-
Sapra P, Hooper AT, O'Donnell CJ, Gerber HP. Investigational antibody drug conjugates for solid tumors. Expert Opin Investig Drugs 2011;20(8):1131-49
-
(2011)
Expert Opin Investig Drugs
, vol.20
, Issue.8
, pp. 1131-49
-
-
Sapra, P.1
Hooper, A.T.2
O'Donnell, C.J.3
Gerber, H.P.4
-
40
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
-
One of the earlier studies proving single agent and combination activity of cetuximab
-
Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004;351(4):337-44 One of the earlier studies proving single agent and combination activity of cetuximab.
-
(2004)
N Engl J Med
, vol.351
, Issue.4
, pp. 337-44
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
-
41
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis CS, Khambata-Ford S, Jonker DJ. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 2008;359(17):1757-64
-
(2008)
N Engl J Med
, vol.359
, Issue.17
, pp. 1757-64
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
-
42
-
-
42649145667
-
Wild-type kras is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008;26:1626-34
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-34
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
-
43
-
-
34047248571
-
Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies
-
DOI 10.1158/0008-5472.CAN-06-4158
-
Benvenuti S, Sartore-Bianchi A, Di Nicolantonio F, et al. Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies. Cancer Res 2007;67(6):2643-8 . Provides mechanism of resistance to EGFR inhibitors in patients with K-ras mutations. (Pubitemid 46548951)
-
(2007)
Cancer Research
, vol.67
, Issue.6
, pp. 2643-2648
-
-
Benvenuti, S.1
Sartore-Bianchi, A.2
Di Nicolantonio, F.3
Zanon, C.4
Moroni, M.5
Veronese, S.6
Siena, S.7
Bardelli, A.8
-
44
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E, Kohne CH, Hitre E. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 2009;360(14):1408-17
-
(2009)
N Engl J Med
, vol.360
, Issue.14
, pp. 1408-17
-
-
Van Cutsem, E.1
Kohne, C.H.2
Hitre, E.3
-
45
-
-
78149250536
-
Randomized, phase iii trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (folfox4) versus folfox4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: The prime study
-
Douillard JY, Siena S, Cassidy J. Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study. J Clin Oncol 2010;28(31):4697-704
-
(2010)
J Clin Oncol
, vol.28
, Issue.31
, pp. 4697-704
-
-
Douillard, J.Y.1
Siena, S.2
Cassidy, J.3
-
46
-
-
51649085865
-
Platinum-based chemotherapy plus cetuximab in head and neck cancer
-
Vermorken JB, Mesia R, Rivera F. Platinum-based chemotherapy plus cetuximab in head and neck cancer. N Engl J Med 2008;359(11):1116-27
-
(2008)
N Engl J Med
, vol.359
, Issue.11
, pp. 1116-27
-
-
Vermorken, J.B.1
Mesia, R.2
Rivera, F.3
-
47
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against her2 for metastatic breast cancer that overexpresses HER2
-
DOI 10.1056/NEJM200103153441101
-
Slamon DJ, Leyland-Jones B, Shak S. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001;344(11):783-92 (Pubitemid 32222155)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.11
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
Fleming, T.7
Eiermann, W.8
Wolter, J.9
Pegram, M.10
Baselga, J.11
Norton, L.12
-
48
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
DOI 10.1200/JCO.20.3.719
-
Vogel CL, Cobleigh MA, Tripathy D. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. Clin Oncol 2002;20(3):719-26 (Pubitemid 34111379)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.3
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
Gutheil, J.C.4
Harris, L.N.5
Fehrenbacher, L.6
Slamon, D.J.7
Murphy, M.8
Novotny, W.F.9
Burchmore, M.10
Shak, S.11
Stewart, S.J.12
Press, M.13
-
49
-
-
34548178720
-
Trastuzumab plus vinorelbine or taxane chemotherapy for HER2-overexpressing metastatic breast cancer: The trastuzumab and vinorelbine or taxane study
-
DOI 10.1002/cncr.22885
-
Burstein HJ, Keshaviah A, Baron AD. Trastuzumab plus vinorelbine or taxane chemotherapy for HER2-overexpressing metastatic breast cancer: the trastuzumab and vinorelbine or taxane study. Cancer 2007;110(5):965-72 (Pubitemid 47312860)
-
(2007)
Cancer
, vol.110
, Issue.5
, pp. 965-972
-
-
Burstein, H.J.1
Keshaviah, A.2
Baron, A.D.3
Hart, R.D.4
Lambert-Falls, R.5
Marcom, P.K.6
Gelman, R.7
Winer, E.P.8
-
50
-
-
33745530224
-
Randomized phase III study of trastuzumab, paclitaxel, and carboplatin compared with trastuzumab and paclitaxel in women with HER-2 - Overexpressing metastatic breast cancer
-
DOI 10.1200/JCO.2005.04.1764
-
Robert N, Leyland-Jones B, Asmar L. Randomized phase III study of trastuzumab, paclitaxel, and carboplatin compared with trastuzumab and paclitaxel in women with HER-2-overexpressing metastatic breast cancer. J Clin Oncol 2006;24(18):2786-92 (Pubitemid 46630577)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.18
, pp. 2786-2792
-
-
Robert, N.1
Leyland-Jones, B.2
Asmar, L.3
Belt, R.4
Llegbodu, D.5
Loesch, D.6
Raju, R.7
Valentine, E.8
Sayre, R.9
Cobleigh, M.10
Albain, K.11
McCullough, C.12
Fuchs, L.13
Slamon, D.14
-
51
-
-
33344478381
-
Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer
-
DOI 10.1056/NEJMoa053028
-
Joensuu H, Kellokumpu-Lehtinen PL, Bono P. Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer. N Engl J Med 2006;354(8):809-20 (Pubitemid 43290919)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.8
, pp. 809-820
-
-
Joensuu, H.1
Kellokumpu-Lehtinen, P.-L.2
Bono, P.3
Alanko, T.4
Kataja, V.5
Asola, R.6
Utriainen, T.7
Kokko, R.8
Hemminki, A.9
Tarkkanen, M.10
Turpeenniemi-Hujanen, T.11
Jyrkkio, S.12
Flander, M.13
Helle, L.14
Ingalsuo, S.15
Johansson, K.16
Jaaskelainen, A.-S.17
Pajunen, M.18
Rauhala, M.19
Kaleva-Kerola, J.20
Salminen, T.21
Leinonen, M.22
Elomaa, I.23
Isola, J.24
more..
-
52
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
DOI 10.1056/NEJMoa052122
-
Romond EH, Perez EA, Bryant J. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 2005;353(16):1673-84 (Pubitemid 41464706)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.16
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
Suman, V.J.4
Geyer Jr., C.E.5
Davidson, N.E.6
Tan-Chiu, E.7
Martino, S.8
Paik, S.9
Kaufman, P.A.10
Swain, S.M.11
Pisansky, T.M.12
Fehrenbacher, L.13
Kutteh, L.A.14
Vogel, V.G.15
Visscher, D.W.16
Yothers, G.17
Jenkins, R.B.18
Brown, A.M.19
Dakhil, S.R.20
Mamounas, E.P.21
Lingle, W.L.22
Klein, P.M.23
Ingle, J.N.24
Wolmark, N.25
more..
-
53
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of her2-positive advanced gastric or gastro-oesophageal junction cancer (toga): A phase 3 open-label randomised controlled trial
-
Provides evidence for efficacy of trastuzumab in HER-2 positive gastric cancer
-
Bang YJ, Van Cutsem E, Feyereislova A. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 2010;376(9742):687-97 . Provides evidence for efficacy of trastuzumab in HER-2 positive gastric cancer.
-
(2010)
Lancet
, vol.376
, Issue.9742
, pp. 687-97
-
-
Bang, Y.J.1
Van Cutsem, E.2
Feyereislova, A.3
-
54
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
DOI 10.1056/NEJMoa032691
-
Hurwitz H, Fehrenbacher L, Novotny W. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350(23):2335-42 (Pubitemid 38702844)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.23
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
Fyfe, G.12
Rogers, B.13
Ross, R.14
Kabbinavar, F.15
-
55
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
DOI 10.1056/NEJMoa061884
-
Sandler A, Gray R, Perry MC. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006;355(24):2542-50 (Pubitemid 44917502)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.24
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
Brahmer, J.4
Schiller, J.H.5
Dowlati, A.6
Lilenbaum, R.7
Johnson, D.H.8
-
56
-
-
37349080670
-
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind phase III trial
-
DOI 10.1016/S0140-6736(07)61904-7, PII S0140673607619047
-
Escudier B, Pluzanska A, Koralewski P. Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet 2007;370(9605):2103-11 (Pubitemid 350296300)
-
(2007)
Lancet
, vol.370
, Issue.9605
, pp. 2103-2111
-
-
Escudier, B.1
Pluzanska, A.2
Koralewski, P.3
Ravaud, A.4
Bracarda, S.5
Szczylik, C.6
Chevreau, C.7
Filipek, M.8
Melichar, B.9
Bajetta, E.10
Gorbunova, V.11
Bay, J.-O.12
Bodrogi, I.13
Jagiello-Gruszfeld, A.14
Moore, N.15
-
57
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K, Wang M, Gralow J. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007;357(26):2666-76
-
(2007)
N Engl J Med
, vol.357
, Issue.26
, pp. 2666-76
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
-
58
-
-
77954700380
-
Phase iii study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
-
Miles DW, Chan A, Dirix LY, Cortes J. Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer. J Clin Oncol 2010;28(20):3239-47
-
(2010)
J Clin Oncol
, vol.28
, Issue.20
, pp. 3239-47
-
-
Miles, D.W.1
Chan, A.2
Dirix, L.Y.3
Cortes, J.4
-
59
-
-
2942657615
-
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
-
DOI 10.1200/JCO.2004.11.022
-
Johnson DH, Fehrenbacher L, Novotny WF. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 2004;22(11):2184-91 (Pubitemid 41095154)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.11
, pp. 2184-2191
-
-
Johnson, D.H.1
Fehrenbacher, L.2
Novotny, W.F.3
Herbst, R.S.4
Nemunaitis, J.J.5
Jablons, D.M.6
Langer, C.J.7
DeVore III, R.F.8
Gaudreault, J.9
Damico, L.A.10
Holmgren, E.11
Kabbinavar, F.12
-
60
-
-
79551520348
-
Treatment-related mortality with bevacizumab in cancer patients: A meta-Analysis
-
Ranpura V, Hapani S, Wu S. Treatment-related mortality with bevacizumab in cancer patients: a meta-Analysis. JAMA 2011;305(5):487-94
-
(2011)
JAMA
, vol.305
, Issue.5
, pp. 487-94
-
-
Ranpura, V.1
Hapani, S.2
Wu, S.3
-
61
-
-
0035169514
-
Rituximab (anti-CD20 monoclonal antibody) as single first-line therapy for patients with follicular lymphoma with a low tumor burden: Clinical and molecular evaluation
-
DOI 10.1182/blood.V97.1.101
-
Colombat P, Salles G, Brousse N. Rituximab (anti-CD20 monoclonal antibody) as single first-line therapy for patients with follicular lymphoma with a low tumor burden: clinical and molecular evaluation. Blood 2001;97(1):101-6 (Pubitemid 32061248)
-
(2001)
Blood
, vol.97
, Issue.1
, pp. 101-106
-
-
Colombat, P.1
Salles, G.2
Brousse, N.3
Eftekhari, P.4
Soubeyran, P.5
Delwail, V.6
Deconinck, E.7
Haioun, C.8
Foussard, C.9
Sebban, C.10
Stamatoullas, A.11
Milpied, N.12
Boue, F.13
Taillan, B.14
Lederlin, P.15
Najman, A.16
Thieblemont, C.17
Montestruc, F.18
Mathieu-Boue, A.19
Benzohra, A.20
Solal-Celigny, P.21
more..
-
62
-
-
13244270361
-
CVP chemotherapy plus rituximab compared with CVP as first-line treatment for advanced follicular lymphoma
-
DOI 10.1182/blood-2004-08-3175
-
Marcus R, Imrie K, Belch A. CVP chemotherapy plus rituximab compared with CVP as first-line treatment for advanced follicular lymphoma. Blood 2005;105(4):1417-23 (Pubitemid 40223656)
-
(2005)
Blood
, vol.105
, Issue.4
, pp. 1417-1423
-
-
Marcus, R.1
Imrie, K.2
Belch, A.3
Cunningham, D.4
Flores, E.5
Catalano, J.6
Solal-Celigny, P.7
Offner, F.8
Walewski, J.9
Raposo, J.10
Jack, A.11
Smith, P.12
-
63
-
-
28544435078
-
Frontline therapy with rituximab added to the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) significantly improves the outcome for patients with advanced-stage follicular lymphoma compared with therapy with CHOP alone: Results of a prospective randomized study of the German Low-Grade Lymphoma Study Group
-
DOI 10.1182/blood-2005-01-0016
-
Hiddemann W, Kneba M, Dreyling M. Frontline therapy with rituximab added to the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) significantly improves the outcome for patients with advanced-stage follicular lymphoma compared with therapy with CHOP alone: results of a prospective randomized study of the German Low-Grade Lymphoma Study Group. Blood 2005;106(12):3725-32 (Pubitemid 41742196)
-
(2005)
Blood
, vol.106
, Issue.12
, pp. 3725-3732
-
-
Hiddemann, W.1
Kneba, M.2
Dreyling, M.3
Schmitz, N.4
Lengfelder, E.5
Schmits, R.6
Reiser, M.7
Metzner, B.8
Harder, H.9
Hegewisch-Becker, S.10
Fischer, T.11
Kropff, M.12
Reis, H.-E.13
Freund, M.14
Wormann, B.15
Fuchs, R.16
Planker, M.17
Schimke, J.18
Eimermacher, H.19
Trumper, L.20
Aldaoud, A.21
Parwaresch, R.22
Unterhalt, M.23
more..
-
64
-
-
23044503407
-
Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: A study by the groupe d'etude des lymphomes de l'adulte
-
DOI 10.1200/JCO.2005.09.131
-
Feugier P, Van Hoof A, Sebban C. Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: a study by the Groupe d'Etude des Lymphomes de l'Adulte. J Clin Oncol 2005;23(18):4117-26 (Pubitemid 46211317)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.18
, pp. 4117-4126
-
-
Feugier, P.1
Van Hoof, A.2
Sebban, C.3
Solal-Celigny, P.4
Bouabdallah, R.5
Ferme, C.6
Christian, B.7
Lepage, E.8
Tilly, H.9
Morschhauser, F.10
Gaulard, P.11
Salles, G.12
Bosly, A.13
Gisselbrecht, C.14
Reyes, F.15
Coiffier, B.16
-
65
-
-
33745982067
-
Rituximab-CHOP versus CHOP alone or with maintenance rituximab in older patients with diffuse large B-cell lymphoma
-
DOI 10.1200/JCO.2005.05.1003
-
Habermann TM, Weller EA, Morrison VA. Rituximab-CHOP versus CHOP alone or with maintenance rituximab in older patients with diffuse large B-cell lymphoma. J Clin Oncol 2006;24(19):3121-7 (Pubitemid 46638950)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.19
, pp. 3121-3127
-
-
Habermann, T.M.1
Weller, E.A.2
Morrison, V.A.3
Gascoyne, R.D.4
Cassileth, P.A.5
Cohn, J.B.6
Dakhil, S.R.7
Woda, B.8
Fisher, R.I.9
Peterson, B.A.10
Horning, S.J.11
-
66
-
-
0035871445
-
Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity
-
Byrd JC, Murphy T, Howard RS, et al. Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity. J Clin Oncol 2001;19(8):2153-64 (Pubitemid 32366969)
-
(2001)
Journal of Clinical Oncology
, vol.19
, Issue.8
, pp. 2153-2164
-
-
Byrd, J.C.1
Murphy, T.2
Howard, R.S.3
Lucas, M.S.4
Goodrich, A.5
Park, K.6
Pearson, M.7
Waselenko, J.K.8
Ling, G.9
Grever, M.R.10
Grillo-Lopez, A.J.11
Rosenberg, J.12
Kunkel, L.13
Flinn, I.W.14
-
67
-
-
23044510136
-
Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia
-
DOI 10.1200/JCO.2005.12.051
-
Keating MJ, O'Brien S, Albitar M. Early results of a chemoimmunotherapy regimen of fludarabine, Cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia. J Clin Oncol 2005;23(18):4079-88 (Pubitemid 46211313)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.18
, pp. 4079-4088
-
-
Keating, M.J.1
O'Brien, S.2
Albitar, M.3
Lerner, S.4
Plunkett, W.5
Giles, F.6
Andreeff, M.7
Cortes, J.8
Faderl, S.9
Thomas, D.10
Koller, C.11
Wierda, W.12
Detry, M.A.13
Lynn, A.14
Kantarjian, H.15
-
68
-
-
19944429446
-
Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: An updated retrospective comparative analysis of CALGB 9712 and CALGB 9011
-
DOI 10.1182/blood-2004-03-0796
-
Byrd JC, Rai K, Peterson BL. Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011. Blood 2005;105(1):49-53 (Pubitemid 40053062)
-
(2005)
Blood
, vol.105
, Issue.1
, pp. 49-53
-
-
Byrd, J.C.1
Rai, K.2
Peterson, B.L.3
Appelbaum, F.R.4
Morrison, V.A.5
Kolitz, J.E.6
Shepherd, L.7
Hines, J.D.8
Schiffer, C.A.9
Larson, R.A.10
-
69
-
-
84857836534
-
Rituximab: Current status as therapy for malignant and benign hematologic disorders
-
Abdulla NE, Ninan MJ, Markowitz AB. Rituximab: current status as therapy for malignant and benign hematologic disorders. BioDrugs 2012;26(2):71-82
-
(2012)
BioDrugs
, vol.26
, Issue.2
, pp. 71-82
-
-
Abdulla, N.E.1
Ninan, M.J.2
Markowitz, A.B.3
-
70
-
-
0037106502
-
Alemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received fludarabine
-
Rai KR, Freter CE, Mercier RJ. Alemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received fludarabine. J Clin Oncol 2002;20(18):3891-7
-
(2002)
J Clin Oncol
, vol.20
, Issue.18
, pp. 3891-7
-
-
Rai, K.R.1
Freter, C.E.2
Mercier, R.J.3
-
71
-
-
0037092951
-
Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: Results of a large international study
-
DOI 10.1182/blood.V99.10.3554
-
Keating MJ, Flinn I, Jain V. Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: results of a large international study. Blood 2002;99(10):3554-61 (Pubitemid 34534522)
-
(2002)
Blood
, vol.99
, Issue.10
, pp. 3554-3561
-
-
Keating, M.J.1
Flinn, I.2
Jain, V.3
Binet, J.-L.4
Hillmen, P.5
Byrd, J.6
Albitar, M.7
Brettman, L.8
Santabarbara, P.9
Wacker, B.10
Rai, K.R.11
-
72
-
-
69849107362
-
Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: Clinical results and prognostic marker analyses from the cll2h study of the german chronic lymphocytic leukemia study group
-
Stilgenbauer S, Zenz T, Winkler D. Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group. J Clin Oncol 2009;27(24):3994-4001
-
(2009)
J Clin Oncol
, vol.27
, Issue.24
, pp. 3994-4001
-
-
Stilgenbauer, S.1
Zenz, T.2
Winkler, D.3
-
73
-
-
33846465547
-
Immunostimulatory monoclonal antibodies for cancer therapy
-
DOI 10.1038/nrc2051, PII NRC2051
-
Melero I, Hervas-Stubbs S, Glennie M, et al. Immunostimulatory monoclonal antibodies for cancer therapy. Nat Rev Cancer 2007;7:95-106 Provides Mechanism Of Action Of CTLA-4. (Pubitemid 46160986)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.2
, pp. 95-106
-
-
Melero, I.1
Hervas-Stubbs, S.2
Glennie, M.3
Pardoll, D.M.4
Chen, L.5
-
74
-
-
36849035139
-
Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): A novel strategy for the treatment of melanoma and other malignancies
-
DOI 10.1002/cncr.23086
-
O'Day SJ, Hamid O, Urba WJ. Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): a novel strategy for the treatment of melanoma and other malignancies. Cancer 2007;110:2614-27 (Pubitemid 350250330)
-
(2007)
Cancer
, vol.110
, Issue.12
, pp. 2614-2627
-
-
O'Day, S.J.1
Hamid, O.2
Urba, W.J.3
-
75
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010;363(8):711-23
-
(2010)
N Engl J Med
, vol.363
, Issue.8
, pp. 711-23
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
76
-
-
38849088141
-
The emerging role of the insulin-like growth factor pathway as a therapeutic target in cancer
-
DOI 10.1634/theoncologist.2007-0199
-
Ryan PD, Goss PE. The emerging role of the insulin-like growth factor pathway as a therapeutic target in cancer. Oncologist 2008;13(1):16-24 (Pubitemid 351206693)
-
(2008)
Oncologist
, vol.13
, Issue.1
, pp. 16-24
-
-
Ryan, P.D.1
Goss, P.E.2
-
77
-
-
0036559535
-
Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis
-
DOI 10.1016/S1535-6108(02)00055-7
-
Lopez T, Hanahan D. Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis. Cancer Cell 2002;1:339-53 (Pubitemid 41039136)
-
(2002)
Cancer Cell
, vol.1
, Issue.4
, pp. 339-353
-
-
Lopez, T.1
Hanahan, D.2
-
78
-
-
33947121226
-
Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation
-
DOI 10.1038/sj.onc.1209955, PII 1209955
-
Jones RA, Campbell CI, Gunther EJ, et al. Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation. Oncogene 2007;26:1636-44 (Pubitemid 46398739)
-
(2007)
Oncogene
, vol.26
, Issue.11
, pp. 1636-1644
-
-
Jones, R.A.1
Campbell, C.I.2
Gunther, E.J.3
Chodosh, L.A.4
Petrik, J.J.5
Khokha, R.6
Moorehead, R.A.7
-
79
-
-
35348815620
-
Phase I dose escalation study of the anti-insulin-like growth factor-I receptor monoclonal antibody CP-751,871in patients with refractory solid tumors
-
DOI 10.1158/1078-0432.CCR-07-1118
-
Haluska P, Shaw HM, Batzel GN. Phase I dose escalation study of the anti insulin-like growth factor-I receptor monoclonal antibody CP-751,871 in patients with refractory solid tumors. Clin Cancer Res 2007;13(19):5834-40 (Pubitemid 47583908)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.19
, pp. 5834-5840
-
-
Haluska, P.1
Shaw, H.M.2
Batzel, G.N.3
Yin, D.4
Molina, J.R.5
Molife, L.R.6
Yap, T.A.7
Roberts, M.L.8
Sharma, A.9
Gualberto, A.10
Adjei, A.A.11
De Bono, J.S.12
-
80
-
-
66349091290
-
Phase ii study of the anti-insulin-like growth factor type 1 receptor antibody cp-751,871 in combination with paclitaxel and carboplatin in previously untreated, locally advanced, or metastatic non-small-cell lung cancer
-
Karp DD, Paz-Ares LG, Novello S. Phase II study of the anti-insulin-like growth factor type 1 receptor antibody CP-751,871 in combination with paclitaxel and carboplatin in previously untreated, locally advanced, or metastatic non-small-cell lung cancer. J Clin Oncol 2009;27(15):2516-22
-
(2009)
J Clin Oncol
, vol.27
, Issue.15
, pp. 2516-222
-
-
Karp, D.D.1
Paz-Ares, L.G.2
Novello, S.3
-
81
-
-
84857656268
-
Phase ii study of figitumumab in patients with recurrent andor metastatic squamous cell carcinoma of the head and neck: Clinical activity and molecular response (gortec 2008-02)
-
Schmitz S, Kaminsky-Forrett MC, Henry S. Phase II study of figitumumab in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck: clinical activity and molecular response (GORTEC 2008-02). Ann Oncol 2012;23(8):2153-61
-
(2012)
Ann Oncol
, vol.23
, Issue.8
, pp. 2153-61
-
-
Schmitz, S.1
Kaminsky-Forrett, M.C.2
Henry, S.3
-
82
-
-
84862907964
-
Phase i/ii trial and pharmacokinetic study of cixutumumab in pediatric patients with refractory solid tumors and ewing sarcoma: A report from the children's oncology group
-
Malempati S, Weigel B, Ingle AM. Phase I/II trial and pharmacokinetic study of cixutumumab in pediatric patients with refractory solid tumors and Ewing sarcoma: a report from the Children's Oncology Group. J Clin Oncol 2012;30(3):256-62
-
(2012)
J Clin Oncol
, vol.30
, Issue.3
, pp. 256-62
-
-
Malempati, S.1
Weigel, B.2
Ingle, A.M.3
-
83
-
-
73349099049
-
Phase i pharmacokinetic, and pharmacodynamic study of amg 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1
-
Tolcher AW, Sarantopoulos J, Patnaik A. Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1. J Clin Oncol 2009;27(34):5800-7
-
(2009)
J Clin Oncol
, vol.27
, Issue.34
, pp. 5800-7
-
-
Tolcher, A.W.1
Sarantopoulos, J.2
Patnaik, A.3
-
84
-
-
80053525113
-
A phase i pharmacokinetic and pharmacodynamic study of dalotuzumab (mk-0646) an anti-insulin-like growth factor-1 receptor monoclonal antibody, in patients with advanced solid tumors
-
Atzori F, Tabernero J, Cervantes A. A phase I pharmacokinetic and pharmacodynamic study of dalotuzumab (MK-0646), an anti-insulin-like growth factor-1 receptor monoclonal antibody, in patients with advanced solid tumors. Clin Cancer Res 2011;17(19):6304-12
-
(2011)
Clin Cancer Res
, vol.17
, Issue.19
, pp. 6304-6312
-
-
Atzori, F.1
Tabernero, J.2
Cervantes, A.3
-
85
-
-
35948943113
-
Inhibition of interleukin-6 signaling with CNTO 328 enhances the activity of bortezomib in preclinical models of multiple myeloma
-
DOI 10.1158/1078-0432.CCR-07-1293
-
Voorhees PM, Chen Q, Kuhn DJ. Inhibition of interleukin-6 signaling with CNTO 328 enhances the activity of bortezomib in preclinical models of multiple myeloma. Clin Cancer Res 2007;13:6469-78 (Pubitemid 350075037)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.21
, pp. 6469-6478
-
-
Voorhees, P.M.1
Chen, Q.2
Kuhn, D.J.3
Small, G.W.4
Hunsucker, S.A.5
Strader, J.S.6
Corringham, R.E.7
Zaki, M.H.8
Nemeth, J.A.9
Orlowski, R.Z.10
-
86
-
-
77957283115
-
Siltuximab a novel anti-interleukin-6 monoclonal antibody, for castleman's disease
-
Shows a high efficacy of siltuximab in Castleman's disease
-
Van Rhee F, Fayad L, Voorhees P. Siltuximab, a novel anti-interleukin-6 monoclonal antibody, for Castleman's disease. J Clin Oncol 2010;28(23):3701-8 Shows a high efficacy of siltuximab in Castleman's disease.
-
(2010)
J Clin Oncol
, vol.28
, Issue.23
, pp. 3701-3708
-
-
Van Rhee, F.1
Fayad, L.2
Voorhees, P.3
-
87
-
-
77953091816
-
Clinical and correlative results of swog s0354: A phase ii trial of cnto328 (siltuximab) a monoclonal antibody against interleukin-6, in chemotherapy-pretreated patients with castration-resistant prostate cancer
-
. Shows a high efficacy of siltuximab in Castleman's disease. 87. Dorff TB, Goldman B, Pinski JK. Clinical and correlative results of SWOG S0354: a phase II trial of CNTO328 (siltuximab) A Monoclonal Antibody Against Interleukin-6, in chemotherapy-pretreated patients with castration-resistant prostate cancer. Clin Cancer Res 2010;16(11):3028- 34
-
(2010)
Clin Cancer Res
, vol.16
, Issue.11
, pp. 3028-34
-
-
Dorff, T.B.1
Goldman, B.2
Pinski, J.K.3
-
88
-
-
0035793623
-
Analysis of biological effects and signaling properties of flt-1 (vegfr-1) and kdr (vegfr-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants
-
Gille H, Kowalski J, Li B. Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants. J Biol Chem 2001;276(5):3222-30
-
(2001)
J Biol Chem
, vol.276
, Issue.5
, pp. 3222-30
-
-
Gille, H.1
Kowalski, J.2
Li, B.3
-
89
-
-
77649213706
-
Phase i pharmacologic and biologic study of ramucirumab (imc-1121b) a fully human immunoglobulin g1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2
-
Spratlin JL, Cohen RB, Eadens M. Phase I pharmacologic and biologic study of ramucirumab (IMC-1121B), a fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2. J Clin Oncol 2010;28(5):780-7
-
(2010)
J Clin Oncol
, vol.28
, Issue.5
, pp. 780-787
-
-
Spratlin, J.L.1
Cohen, R.B.2
Eadens, M.3
-
90
-
-
0037126021
-
Involvement of pd-l1 on tumor cells in the escape from host immune system and tumor immunotherapy by pd-l1 blockade
-
Provides Mechanism For The PD-L1 And PD-1 pathway.
-
Iwai Y, Ishida M, Tanaka Y. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci USA 2002;99(19):12293-7 . Provides Mechanism For The PD-L1 And PD-1 pathway.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.19
, pp. 12293-7
-
-
Iwai, Y.1
Ishida, M.2
Tanaka, Y.3
-
91
-
-
33847401888
-
Contribution of the pd-l1/pd-1 pathway to t-cell exhaustion: An update on implications for chronic infections and tumor evasion
-
Provides mechanism for the PD-L1 and PD-1 pathway
-
Blank C, Mackensen A. Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion. Cancer Immunol Immunother 2007;56(5):739-44 . Provides mechanism for the PD-L1 and PD-1 pathway.
-
(2007)
Cancer Immunol Immunother
, vol.56
, Issue.5
, pp. 739-44
-
-
Blank, C.1
Mackensen, A.2
-
92
-
-
33645736792
-
Tumor b7-h1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up
-
Thompson RH, Kuntz SM, Leibovich BC. Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up. Cancer Res 2006;66(7):3381-4
-
(2006)
Cancer Res
, vol.66
, Issue.7
, pp. 3381-4
-
-
Thompson, R.H.1
Kuntz, S.M.2
Leibovich, B.C.3
-
93
-
-
77954899030
-
Phase i study of single-Agent antiprogrammed death-1 (mdx-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer JR, Drake CG, Wollner I. Phase I study of single-Agent antiprogrammed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol 2010;28(19):3167-74
-
(2010)
J Clin Oncol
, vol.28
, Issue.19
, pp. 3167-74
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
-
94
-
-
49649114804
-
Phase i safety and pharmacokinetic study of ct-011 a humanized antibody interacting with pd-1, in patients with advanced hematologic malignancies
-
Berger R, Rotem-Yehudar R, Slama G. Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies. Clin Cancer Res 2008;14(10):3044-51
-
(2008)
Clin Cancer Res
, vol.14
, Issue.10
, pp. 3044-3051
-
-
Berger, R.1
Rotem-Yehudar, R.2
Slama, G.3
-
95
-
-
77957701558
-
The pd-1/pd-l1 axis modulates the natural killer cell versus multiple myeloma effect: A therapeutic target for ct-011, a novel monoclonal anti-pd-1 antibody
-
Benson DM Jr., Bakan CE, Mishra A. The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody. Blood 2010;116(13):2286-94
-
(2010)
Blood
, vol.116
, Issue.13
, pp. 2286-94
-
-
Benson Jr., D.M.1
Bakan, C.E.2
Mishra, A.3
-
96
-
-
80053161751
-
Anti-pd-1 synergizes with cyclophosphamide to induce potent anti-tumor vaccine effects through novel mechanisms
-
Mkrtichyan M, Najjar YG, Raulfs EC. Anti-PD-1 synergizes with cyclophosphamide to induce potent anti-tumor vaccine effects through novel mechanisms. Eur J Immunol 2011;41(10):2977-86
-
(2011)
Eur J Immunol
, vol.41
, Issue.10
, pp. 2977-2986
-
-
Mkrtichyan, M.1
Najjar, Y.G.2
Raulfs, E.C.3
-
97
-
-
79958057037
-
The emerging role of ofatumumab in the treatment of chronic lymphocytic leukemia
-
Nabhan C, Kay NE. The emerging role of ofatumumab in the treatment of chronic lymphocytic leukemia. Clin Med Insights Oncol 2011;5:45-53
-
(2011)
Clin Med Insights Oncol
, vol.5
, pp. 45-53
-
-
Nabhan, C.1
Kay, N.E.2
-
98
-
-
81055148076
-
Ofatumumab is active in patients with fludarabine-refractory cll irrespective of prior rituximab: Results from the phase 2 international study
-
Wierda WG, Padmanabhan S, Chan GW. Ofatumumab is active in patients with fludarabine-refractory CLL irrespective of prior rituximab: results from the phase 2 international study. Blood 2011;118(19):5126-9
-
(2011)
Blood
, vol.118
, Issue.19
, pp. 5126-9
-
-
Wierda, W.G.1
Padmanabhan, S.2
Chan, G.W.3
-
99
-
-
84857349967
-
Obinutuzumab for the treatment of lymphoproliferative disorders
-
Owen C, Stewart DA. Obinutuzumab for the treatment of lymphoproliferative disorders. Expert Opin Biol Ther 2012;12(3):343-51
-
(2012)
Expert Opin Biol Ther
, vol.12
, Issue.3
, pp. 343-51
-
-
Owen, C.1
Stewart, D.A.2
-
100
-
-
77951829072
-
Veltuzumab (humanized anti-cd20 monoclonal antibody): Characterization current clinical results and future prospects
-
Goldenberg DM, Morschhauser F, Wegener WA. Veltuzumab (humanized anti-CD20 monoclonal antibody): characterization, current clinical results, and future prospects. Leuk Lymphoma 2010;51(5):747-54
-
(2010)
Leuk Lymphoma
, vol.51
, Issue.5
, pp. 747-54
-
-
Goldenberg, D.M.1
Morschhauser, F.2
Wegener, W.A.3
-
101
-
-
79952092706
-
Phase ii study of the antibody drug conjugate trastuzumab-dm1 for the treatment of human epidermal growth factor receptor 2 (her2)-positive breast cancer after prior her2-directed therapy
-
Burris HA III, Rugo HS, Vukelja SJ. Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer after prior HER2-directed therapy. J Clin Oncol 2011;29(4):398-404
-
(2011)
J Clin Oncol
, vol.29
, Issue.4
, pp. 398-404
-
-
Burris III, H.A.1
Rugo, H.S.2
Vukelja, S.J.3
-
102
-
-
78951477856
-
Results of a pivotal phase 2 study of brentuximab vedotin (sgn-35) in patients with relapsed or refractory hodgkin lymphoma
-
Initial study showing a high efficacy of brentuximab in relapsed HD
-
Chen R, Gopal AK. Results of a Pivotal Phase 2 Study of Brentuximab vedotin (SGN-35) in Patients with Relapsed or Refractory Hodgkin Lymphoma. Blood (ASH Annual Meeting Abstracts) 2010;116:283 . Initial study showing a high efficacy of brentuximab in relapsed HD.
-
(2010)
Blood (ASH Annual Meeting Abstracts)
, vol.116
, pp. 283
-
-
Chen, R.1
Gopal, A.K.2
-
103
-
-
77951648118
-
Safety, pharmacokinetics, and preliminary clinical activity of inotuzumab ozogamicin, a novel immunoconjugate for the treatment of b-cell non-hodgkin's lymphoma: Results of a phase i study
-
Advani A, Coiffier B, Czuczman MS. Safety, pharmacokinetics, and preliminary clinical activity of inotuzumab ozogamicin, a novel immunoconjugate for the treatment of B-cell non-Hodgkin's lymphoma: results of a phase I study. J Clin Oncol 2010;28(12):2085-93
-
(2010)
J Clin Oncol
, vol.28
, Issue.12
, pp. 2085-93
-
-
Advani, A.1
Coiffier, B.2
Czuczman, M.S.3
-
104
-
-
84862786326
-
Inotuzumab ozogamicin an anti-cd22-calecheamicin conjugate for refractory and relapsed acute lymphocytic leukaemia: A phase 2 study
-
A Study of the Safety and Pharmacokinetics of Escalating Doses of DSTP3086S in Patients with Metastatic Castration-Resistant Prostate Cancer. NCT01283373
-
Kantarjian H, Thomas D, Jorgensen J. Inotuzumab ozogamicin, an anti-CD22-calecheamicin conjugate, for refractory and relapsed acute lymphocytic leukaemia: a phase 2 study. Lancet Oncol 2012;13(4):403-11 A Study of the Safety and Pharmacokinetics of Escalating Doses of DSTP3086S in Patients with Metastatic Castration-Resistant Prostate Cancer. NCT01283373
-
(2012)
Lancet Oncol
, vol.13
, Issue.4
, pp. 403-11
-
-
Kantarjian, H.1
Thomas, D.2
Jorgensen, J.3
-
105
-
-
84872178954
-
Asg-5me: A novel antibody-drug conjugate (adc) therapy for prostate, pancreatic, and gastric cancers [abstract # 230]
-
Gudas M, An Z, Morrison RK, Morrison KJ. ASG-5ME: a novel antibody-drug conjugate (ADC) therapy for prostate, pancreatic, and gastric cancers [abstract # 230]. ASCO; 2010
-
(2010)
ASCO
-
-
Gudas, M.1
An, Z.2
Morrison, R.K.3
Morrison, K.J.4
-
106
-
-
0026684815
-
Rapid tumor penetration of a single-chain fv and comparison with other immunoglobulin forms
-
Yokota T, Milenic DE, Whitlow M, Schlom J. Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res 1992;52(12):3402-8
-
(1992)
Cancer Res
, vol.52
, Issue.12
, pp. 3402-8
-
-
Yokota, T.1
Milenic, D.E.2
Whitlow, M.3
Schlom, J.4
-
107
-
-
1342282157
-
Rituximab infusion promotes rapid complement depletion and acute CD20 loss in chronic lymphocytic leukemia
-
Kennedy AD, Beum PV, Solga MD. Rituximab infusion promotes rapid complement depletion and acute CD20 loss in chronic lymphocytic leukemia. J Immunol 2004;172(5):3280-8 (Pubitemid 38263720)
-
(2004)
Journal of Immunology
, vol.172
, Issue.5
, pp. 3280-3288
-
-
Kennedy, A.D.1
Beum, P.V.2
Solga, M.D.3
DiLillo, D.J.4
Lindorfer, M.A.5
Hess, C.E.6
Densmore, J.J.7
Williams, M.E.8
Taylor, R.P.9
-
108
-
-
79251570884
-
Daratumumab, a novel therapeutic human cd38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors
-
de Weers M, Tai YT, van der Veer MS. Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors. J Immunol 2011;186(3):1840-8
-
(2011)
J Immunol
, vol.186
, Issue.3
, pp. 8
-
-
De Weers, M.1
Tai, Y.T.2
Van Der Veer, M.S.3
-
109
-
-
79955974149
-
Combination anti-cd74 (milatuzumab) and anti-cd20 (rituximab) monoclonal antibody therapy has in vitro and in vivo activity in mantle cell lymphoma
-
Alinari L, Yu B, Christian BA, Yan F. Combination anti-CD74 (milatuzumab) and anti-CD20 (rituximab) monoclonal antibody therapy has in vitro and in vivo activity in mantle cell lymphoma. Blood 2011;117(17):4530-41
-
(2011)
Blood
, vol.117
, Issue.17
, pp. 4530-41
-
-
Alinari, L.1
Yu, B.2
Christian, B.A.3
Yan, F.4
-
110
-
-
79958093024
-
Proapoptotic signaling activity of the anti-cd40 monoclonal antibody dacetuzumab circumvents multiple oncogenic transformation events and chemosensitizes nhl cells
-
Lewis TS, McCormick RS, Stone IJ. Proapoptotic signaling activity of the anti-CD40 monoclonal antibody dacetuzumab circumvents multiple oncogenic transformation events and chemosensitizes NHL cells. Leukemia 2011;25(6):1007-16
-
(2011)
Leukemia
, vol.25
, Issue.6
, pp. 1007-16
-
-
Lewis, T.S.1
McCormick, R.S.2
Stone, I.J.3
-
111
-
-
84862672400
-
Phase i trial of anti-cs1 monoclonal antibody elotuzumab in combination with bortezomib in the treatment of relapsed/refractory multiple myeloma
-
Jakubowiak AJ, Benson DM, Bensinger W. Phase I trial of anti-CS1 monoclonal antibody elotuzumab in combination with bortezomib in the treatment of relapsed/refractory multiple myeloma. J Clin Oncol 2012
-
(2012)
J Clin Oncol
-
-
Jakubowiak, A.J.1
Benson, D.M.2
Bensinger, W.3
-
112
-
-
77950352683
-
Anti-leukemic activity of lintuzumab (sgn-33) in preclinical models of acute myeloid leukemia
-
Sutherland MK, Yu C, Lewis TS. Anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia. MAbs 2009;1(5):481-90
-
(2009)
MAbs
, vol.1
, Issue.5
, pp. 481-90
-
-
Sutherland, M.K.1
Yu, C.2
Lewis, T.S.3
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