Effects of a continuous-combined regimen of low-dose hormone therapy (oestradiol and norethindrone acetate) and tibolone on the quality of life in symptomatic postmenopausal women: A double-blind, randomised study

Maturitas

Volumn 74, Issue 2, 2013, Pages 172-178

  Polisseni, Alvaro Fernando ^a   Andrade, Amaury Teixeira Leite ^a   Ribeiro, Luiz Claudio ^a   Castro, Isabela Queirós ^a   Brandão, Marcos ^a   Polisseni, Fernanda ^a   De Oliveira Guerra, Martha ^a  

^a FEDERAL UNIVERSITY OF JUIZ DE FORA   (Brazil)

Author keywords

Hormonal therapy; Postmenopausal; Quality of life

Indexed keywords

CALCIUM CARBONATE; COLECALCIFEROL; ESTRADIOL PLUS NORETHISTERONE ACETATE; TIBOLONE;

ABDOMINAL PAIN; ADULT; ARTICLE; BLEEDING; CLIMACTERIUM; CLINICAL EVALUATION; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; ESTROGEN THERAPY; FEMALE; HUMAN; INSOMNIA; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MENOPAUSAL SYNDROME; MYALGIA; OUTPATIENT; POSTMENOPAUSE; QUALITY OF LIFE; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SEXUAL BEHAVIOR; SEXUAL FUNCTION; TREATMENT RESPONSE; VASOMOTOR DISORDER; WOMEN HEALTH QUESTIONNAIRE;

AFFECT; CALCIUM CARBONATE; CHOLECALCIFEROL; CONTRACEPTIVES, ORAL, SYNTHETIC; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; ESTRADIOL; ESTROGEN RECEPTOR MODULATORS; ESTROGEN REPLACEMENT THERAPY; ESTROGENS; FEMALE; HUMANS; MIDDLE AGED; NORETHINDRONE; NORPREGNENES; POSTMENOPAUSE; QUALITY OF LIFE; QUESTIONNAIRES; SEXUAL BEHAVIOR; STATISTICS, NONPARAMETRIC; VITAMINS;

EID: 84872182775     PISSN: 03785122     EISSN: 18734111     Source Type: Journal    
DOI: 10.1016/j.maturitas.2012.11.001     Document Type: Article

References (42)

1. L.L.F. Galvão, M.C.S. Farias, and P.R. Azevedo Prevalência de transtornos mentais comuns e avaliação da qualidade de vida no climatério Revista da Associacao Medica Brasileira 53 2007 414 420
2. P. Chedraui, W. Aguirre, L. Hidalgo, and L. Fayad Assessing menopausal symptoms among healthy middle aged women with the menopause rating scale Maturitas 57 2007 271 278
3. A.M. Fonseca, V.R. Bagnoli, and E.C. Baracat Terapia estrogênica no climatério: qual a melhor via? Uma resposta baseada nas melhores evidências Femina 28 2010 89 99
4. A.M. Pinto-Neto, and D.M. Conde Qualidade de vida Revista Brasileira de Ginecologia e Obstetrícia 30 2008 235 237
5. D.R.S. De Lorenzi, and E. Baracat Climatério e qualidade de vida Femina 33 2005 899 903
6. J.E. Rossouw Prescribing postmenopausal hormone therapy to women in their 50s in the post-women's health initiative era Maturitas 65 2010 179 180
7. S.E.V. Zahar, A.M. Pinto-Neto, and D.M. Conde Qualidade de vida em usuárias e não usuárias de Terapia de Reposição Hormonal Revista da Associacao Medica Brasileira 51 2005 133 138
8. C.K. Moriyama, B. Oneda, F.R. Bernardo, and C.G. Cardoso Junior A randomized placebo-controlled trial of the effects of physical exercises and estrogen therapy on health-related quality of life in postmenopausal women Menopause 15 2008 613 618
9. M. Waaseth, K. Bakken, and E. Lund Patterns of hormone therapy in the Norwegian women and cancer study (NOWAC) 1996-2005 Maturitas 63 2009 220 226
10. A. Gompel, S. Rozemberg, and D.H. Barlow The EMAS update on clinical recommendations on postmenopausal hormone replacement therapy Maturitas 61 2008 227 232
11. M. Gambacciani, M. Ciaponi, and B. Cappagli Effects of low-dose, continuous combined estradiol and noretisterone acetate on menopausal quality of life in early postmenopausal women Maturitas 44 2003 157 163
12. M. González, G. Viáfara, F. Caba, and E. Molina Sexual function, menopause and hormone replacement therapy (HTR) Maturitas 48 2004 411 420
13. S. Palacios Androgens and female sexual function Maturitas 57 2007 61 65
14. B. Lee, B.M. Kang, B.K. Yoon, H. Choi, H.M. Park, and J.G. Kim Efficacy and tolerability of estradiol 1 mg and drospirenona 2 mg in postmenopausal Korean women: a double-blind, randomized, placebo-controlled, multicenter study Maturitas 57 2007 361 369
15. E.A. Nijland, S. Weimar, and A. Davis Effects of tibolone and raloxifene on health-related quality of life and sexual function Maturitas 58 2007 164 173
16. B. Ettinger Rationale for use of lower estrogen doses for postmenopausal hormone therapy Maturitas 57 2007 81 84
17. J.F. Paula, J.M. Soares Junior, M. Haidar, G.R. Lima, and E.C. Baracat The benefits of androgens combined with hormone replacement therapy regarding to patients with postmenopausal sexual symptoms Maturitas 56 2007 69 77
18. R.E. Nappi, and M. Lachowsky Menopause and sexuality: prevalence of symptoms and impact on quality of life Maturitas 63 2009 138 141
19. M. Gast, M.A. Freedman, and A.J. Vieweg A randomized study of low-dose conjugated estrogens on sexual function and quality of life in postmenopausal women Menopause 16 2009 1 10
20. S. Eviö, T. Pekkarinen, H. Sintonen, A. Titinen, and M.J. Välimaki The effect of hormone therapy on the health-related quality of life in elderly women Maturitas 56 2007 122 128
21. M. Hunter The Women's Health Questionnaire: a measure of mid-Aged women's perception of their emotional and physical health Psychology and Health 20 1992 45 54
22. R.S. Dias, C.C. Ramos, and F. Kerr-Corrêa Adaptação para o português do questionário de auto-Avaliação de percepção de saúde física e mental da mulher de meia-idade-Questionário da Saúde da Mulher Revista de Psiquiatria Clínica 29 2002 181 189
23. M. Hunter The Women's Health Questionnaire (WHQ): frequently asked questions (FAQ)-review. Health and quality of life outcomes Psychology and Health 1 2004 35 39
24. W.J. Conover Practical nonparametric statistics 3rd ed. 1999 John Wiley and Sons New York
25. E. Graeser, U. Mellinger, J. Endricat, K. Ertam, and C. Holtz A multicenter, prospective, randomized, double-blind, placebo-controlled study to investigate the efficacy of a continuous-combined hormone therapy preparation containing 1 mg estradiol valerato/2 mg dienogest on hot flushes in postmenopausal women Maturitas 58 2007 201 207
26. Z.A. Kamenov, M.K. Todorova, and V.G. Christov Effect of tibolone on sexual function in late postmenopausal women Folia Medica 49 2007 41 48
27. J. Mameri Filho, M.A. Haidar, and J. Soares Junior Efeitos da associação estro-Androgênica em mulheres na pós-menopausa Revista Brasileira de Ginecologia e Obstetrícia 27 2005 118 124
28. R.E. Hedrick, R.T. Ackerman, and C. Koltun Transdermal estradiol gel 0.1% for the treatment of vasomotor symptoms in postmenopausal women Menopause 16 2009 132 140
29. S. Aédo, I. Schiattino, and G. Cavada Quality of life in climacteric Chilean women treated with low-dose estrogen Maturitas 61 2008 248 251
30. C. Battaglia, A. Cianciosi, F. Mancini, N. Persico, and G. Sisti Angelic versus activelle in normotensive postmenopausal women Menopause 16 2009 803 809
31. B. Baksu, A. Baksu, N. Göker, and S. Citak Do different delivery systems of hormone therapy have different effects on psychological symptoms in surgically menopausal women? Maturitas 62 2009 140 145
32. A. Kökçü, M.B. Centikaia, F. Yanik, T. Alper, and E. Malatialioglu The comparison of effects of tibolone and conjugated estrogen-medroxyprogesterone acetate therapy on sexual performance in postmenopausal women Maturitas 36 2000 75 80
33. D. Hudita, C. Posea, and M.R. Rusu Efficacy and safety of oral tibolona 1.25 or 2.5 mg/day vs. placebo in postmenopausal women European Review for Medical and Pharmacological Sciences 7 2003 117 125
34. K. Modeska, and S. Cummings Tibolone for postmenopausal women: review of randomized trials Journal of Clinical Endocrinology and Metabolism 87 2002 16 23
35. H. Kloosterboer Tissue-selectivity: the mechanism of action of tibolone Maturitas 48 2004 30 40
36. A. Somunkiran, C.T. Erel, F. Demirci, and M.L. Senturk The effect of tibolone versus 17 beta-estradiol on climacteric symptoms in women with surgical menopause: a randomized, cross-over study Maturitas 56 2007 61 68
37. F.R. Péres-Lópes, M. Brincat, and C.T. Erel EMAS position statement: vitamin D and postmenopausal health Maturitas 71 2012 83 88
38. S. Motsinger, D. Lazovich, R.F. MacLehose, C.J. Torkelson, and K. Robien Vitamin D intake and mental health-related quality of life in older women: the Iowa Women's Health Study Maturitas 71 2012 267 273
39. M.D. Witham, L.J. Crighton, N.D. Gillespie, A.D. Struthers, and M. McMurdo The effects of vitamin D supplementation on physical function and quality of life in older patients with heart failure: a randomized controlled trial Circulation. Heart Failure 3 2010 195 201
40. D.R.S. De Lorenzi, E.C. Baracat, B. Saciloto, and I. Padilha Junior Fatores associados à qualidade de vida após menopausa Revista da Associacao Medica Brasileira 52 2006 312 327
41. D.R.S. De Lorenzi Avaliação da qualidade de vida no climatério Revista da Associacao Medica Brasileira 30 2008 103 106
42. D.M. Conde, A.M. Pinto-Neto, C. Cabello, and D.S. Sá Menopause symptoms and quality of life in women aged 45-65 years with and without breast cancer Menopause 12 2005 436 443