Effect of exercise on mouse liver and brain bioenergetic infrastructures

Experimental Physiology

Volumn 98, Issue 1, 2013, Pages 207-219

  Lezi, E ^a   Lu, Jianghua ^b   Burns, Jeffrey M ^b   Swerdlow, Russell H ^b  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CITRATE SYNTHASE; CYCLIC AMP; CYTOCHROME C OXIDASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LACTIC ACID; MITOCHONDRIAL TRANSCRIPTION FACTOR A; MONOCARBOXYLATE TRANSPORTER 2; NUCLEAR RESPIRATORY FACTOR 1; SIRTUIN 1; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOENERGY; BRAIN; CELL GROWTH; EXERCISE; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; LACTATE BLOOD LEVEL; LIVER; LIVER MITOCHONDRION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TREADMILL EXERCISE;

EID: 84872173552     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2012.066688     Document Type: Article

References (42)

1. Aguiar AS Jr, Tuon T, Pinho CA, Silva LA, Andreazza AC, Kapczinski F, Quevedo J, Streck EL & Pinho RA (2007). Mitochondrial IV complex and brain neurothrophic derived factor responses of mice brain cortex after downhill training. Neurosci Lett 426, 171-174.
2. Aguiar AS Jr, Tuon T, Pinho CA, Silva LA, Andreazza AC, Kapczinski F, Quevedo J, Streck EL & Pinho RA (2008). Intense exercise induces mitochondrial dysfunction in mice brain. Neurochem Res 33, 51-58.
3. Berchtold NC, Castello N & Cotman CW (2010). Exercise and time-dependent benefits to learning and memory. Neuroscience 167, 588-597.
4. Berthet C, Lei H, Thevenet J, Gruetter R, Magistretti PJ & Hirt L (2009). Neuroprotective role of lactate after cerebral ischemia. J Cereb Blood Flow Metab 29, 1780-1789.
5. Billat VL, Mouisel E, Roblot N & Melki J (2005). Inter- and intrastrain variation in mouse critical running speed. J Appl Physiol 98, 1258-1263.
6. Bonen A, Heynen M & Hatta H (2006). Distribution of monocarboxylate transporters MCT1-MCT8 in rat tissues and human skeletal muscle. Appl Physiol Nutr Metab 31, 31-39.
7. Camacho RC, Donahue EP, James FD, Berglund ED & Wasserman DH (2006). Energy state of the liver during short-term and exhaustive exercise in C57BL/6J mice. Am J Physiol Endocrinol Metab 290, E405-E408.
8. + metabolism and SIRT1 activity. Nature 458, 1056-1060.
9. Cao W, Collins QF, Becker TC, Robidoux J, Lupo EG Jr, Xiong Y, Daniel KW, Floering L & Collins S (2005). p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis. J Biol Chem 280, 42731-42737.
10. Chen MJ & Russo-Neustadt AA (2009). Running exercise-induced up-regulation of hippocampal brain-derived neurotrophic factor is CREB-dependent. Hippocampus 19, 962-972.
11. Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK & Puigserver P (2007). mTOR controls mitochondrial oxidative function through a YY1-PGC-1α transcriptional complex. Nature 450, 736-740.
12. Devi SA & Kiran TR (2004). Regional responses in antioxidant system to exercise training and dietary vitaminE in aging rat brain. Neurobiol Aging 25, 501-508.
13. Fabel K, Tam B, Kaufer D, Baiker A, Simmons N, Kuo CJ & Palmer TD (2003). VEGF is necessary for exercise-induced adult hippocampal neurogenesis. Eur J Neurosci 18, 2803-2812.
14. Finkbeiner S (2000). Calcium regulation of the brain-derived neurotrophic factor gene. Cell Mol Life Sci 57, 394-401.
15. Ghosh S, Patel N, Rahn D, McAllister J, Sadeghi S, Horwitz G, Berry D, Wang KX & Swerdlow RH (2007). The thiazolidinedione pioglitazone alters mitochondrial function in human neuron-like cells. Mol Pharmacol 71, 1695-1702.
16. Hardie DG (2007). AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nat Rev Mol Cell Biol 8, 774-785.
17. Hawley SA, Davison M, Woods A, Davies SP, Beri RK, Carling D & Hardie DG (1996). Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine172 as the major site at which it phosphorylates AMP-activated protein kinase. J Biol Chem 271, 27879-27887.
18. Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B & Montminy M (2001). CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature 413, 179-183.
19. Hoene M, Lehmann R, Hennige AM, Pohl AK, Haring HU, Schleicher ED & Weigert C (2009). Acute regulation of metabolic genes and insulin receptor substrates in the liver of mice by one single bout of treadmill exercise. J Physiol 587, 241-252.
20. Hoene M & Weigert C (2010). The stress response of the liver to physical exercise. Exerc Immunol Rev 16, 163-183.
21. 2 uptake in human brain during recovery from maximal exercise. J Physiol 522, 159-164.
22. Jackson VN, Price NT, Carpenter L & Halestrap AP (1997). Cloning of the monocarboxylate transporter isoform MCT2 from rat testis provides evidence that expression in tissues is species-specific and may involve post-transcriptional regulation. Biochem J 324, 447-453.
23. Jia B, Wang X, Kang A, Wen Z, Yao W & Xie L (2012). The effects of long term aerobic exercise on the hemorheology in rats fed with high-fat diet. Clin Hemorheol Microcirc 51, 117-127.
24. Little JP, Safdar A, Cermak N, Tarnopolsky MA & Gibala MJ (2010). Acute endurance exercise increases the nuclear abundance of PGC-1α in trained human skeletal muscle. Am J Physiol Regul Integr Comp Physiol 298, R912-R917.
25. Liu YF, Chen HI, Wu CL, Kuo YM, Yu L, Huang AM, Wu FS, Chuang JI & Jen CJ (2009). Differential effects of treadmill running and wheel running on spatial or aversive learning and memory: roles of amygdalar brain-derived neurotrophic factor and synaptotagminI. J Physiol 587, 3221-3231.
26. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF & Turner RC (1985). Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412-419.
27. Navarro A, Gomez C, López-Cepero JM & Boveris A (2004). Beneficial effects of moderate exercise on mice aging: survival, behavior, oxidative stress, and mitochondrial electron transfer. Am J Physiol Regul Integr Comp Physiol 286, R505-R511.
28. Pellerin L, Bouzier-Sore AK, Aubert A, Serres S, Merle M, Costalat R & Magistretti PJ (2007). Activity-dependent regulation of energy metabolism by astrocytes: an update. Glia 55, 1251-1262.
29. Rasmussen P, Brassard P, Adser H, Pedersen MV, Leick L, Hart E, Secher NH, Pedersen BK & Pilegaard H (2009). Evidence for a release of brain-derived neurotrophic factor from the brain during exercise. Exp Physiol 94, 1062-1069.
30. Richter EA, Turcotte L, Hespel P & Kiens B (1992). Metabolic responses to exercise. Effects of endurance training and implications for diabetes. Diabetes Care 15, 1767-1776.
31. Rockl KS, Witczak CA & Goodyear LJ (2008). Signaling mechanisms in skeletal muscle: acute responses and chronic adaptations to exercise. IUBMB Life 60, 145-153.
32. Salminen A, Hyttinen JM & Kaarniranta K (2011). AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan. J Mol Med (Berl) 89, 667-676.
33. Somani SM & Husain K (1996). Exercise training alters kinetics of antioxidant enzymes in rat tissues. Biochem Mol Biol Int 38, 587-595.
34. Steiner JL, Murphy EA, McClellan JL, Carmichael MD & Davis JM (2011). Exercise training increases mitochondrial biogenesis in the brain. J Appl Physiol 111, 1066-1071.
35. Stewart KJ (2004). Role of exercise training on cardiovascular disease in persons who have type2 diabetes and hypertension. Cardiol Clin 22, 569-586.
36. Suzuki A, Stern SA, Bozdagi O, Huntley GW, Walker RH, Magistretti PJ & Alberini CM (2011). Astrocyte-neuron lactate transport is required for long-term memory formation. Cell 144, 810-823.
37. van Hall G, Strømstad M, Rasmussen P, Jans O, Zaar M, Gam C, Quistorff B, Secher NH & Nielsen HB (2009). Blood lactate is an important energy source for the human brain. J Cereb Blood Flow Metab 29, 1121-1129.
38. Vaynman S, Ying Z & Gómez-Pinilla F (2004). Exercise induces BDNF and synapsinI to specific hippocampal subfields. J Neurosci Res 76, 356-362.
39. Veneman T, Mitrakou A, Mokan M, Cryer P & Gerich J (1994). Effect of hyperketonemia and hyperlacticacidemia on symptoms, cognitive dysfunction, and counterregulatory hormone responses during hypoglycemia in normal humans. Diabetes 43, 1311-1317.
40. Viña J, Gomez-Cabrera MC, Borras C, Froio T, Sanchis-Gomar F, Martinez-Bello VE & Pallardo FV. (2009). Mitochondrial biogenesis in exercise and in ageing. Adv Drug Deliv Rev 61, 1369-1374.
41. Wilson DO & Johnson P (2000). Exercise modulates antioxidant enzyme gene expression in rat myocardium and liver. J Appl Physiol 88, 1791-1796.
42. Wu SY, Wang TF, Yu L, Jen CJ, Chuang JI, Wu FS, Wu CW & Kuo YM (2011). Running exercise protects the substantia nigra dopaminergic neurons against inflammation-induced degeneration via the activation of BDNF signaling pathway. Brain Behav Immun 25, 135-146.