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Volumn 33, Issue 2, 2013, Pages 231-238

Activation of FoxO3a/Bim axis in patients with Primary Biliary Cirrhosis

Author keywords

Apoptosis; Cholestasis; FoxO transcription factors; Liver

Indexed keywords

BIM PROTEIN; CASPASE 3; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOX03A; UNCLASSIFIED DRUG;

EID: 84872157415     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12030     Document Type: Article
Times cited : (23)

References (34)
  • 1
    • 20944443874 scopus 로고    scopus 로고
    • Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid
    • Amano K, Leung PS, Rieger R, et al. Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid. J Immunol 2005; 174: 5874-83.
    • (2005) J Immunol , vol.174 , pp. 5874-5883
    • Amano, K.1    Leung, P.S.2    Rieger, R.3
  • 2
    • 77953284855 scopus 로고    scopus 로고
    • Demographic, lifestyle, medical and familial factors associated with primary biliary cirrhosis
    • Corpechot C, Chretien Y, Chazouilleres O, Poupon R. Demographic, lifestyle, medical and familial factors associated with primary biliary cirrhosis. J Hepatol 2010; 53: 162-9.
    • (2010) J Hepatol , vol.53 , pp. 162-169
    • Corpechot, C.1    Chretien, Y.2    Chazouilleres, O.3    Poupon, R.4
  • 3
    • 75949084877 scopus 로고    scopus 로고
    • Experimental evidence on the immunopathogenesis of primary biliary cirrhosis
    • Selmi C, Meda F, Kasangian A, et al. Experimental evidence on the immunopathogenesis of primary biliary cirrhosis. Cell Mol Immunol 2010; 7: 1-10.
    • (2010) Cell Mol Immunol , vol.7 , pp. 1-10
    • Selmi, C.1    Meda, F.2    Kasangian, A.3
  • 4
    • 0031005366 scopus 로고    scopus 로고
    • Nuclear DNA fragmentation and expression of Bcl-2 in primary biliary cirrhosis
    • Koga H, Sakisaka S, Ohishi M, Sata M, Tanikawa K. Nuclear DNA fragmentation and expression of Bcl-2 in primary biliary cirrhosis. Hepatology 1997; 25: 1077-84.
    • (1997) Hepatology , vol.25 , pp. 1077-1084
    • Koga, H.1    Sakisaka, S.2    Ohishi, M.3    Sata, M.4    Tanikawa, K.5
  • 5
    • 0034614897 scopus 로고    scopus 로고
    • Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
    • Sauter B, Albert ML, Francisco L, et al. Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J Exp Med 2000; 191: 423-34.
    • (2000) J Exp Med , vol.191 , pp. 423-434
    • Sauter, B.1    Albert, M.L.2    Francisco, L.3
  • 6
    • 0034953329 scopus 로고    scopus 로고
    • Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis
    • Odin JA, Huebert RC, Casciola-Rosen L, LaRusso NF, Rosen A. Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis. J Clin Invest 2001; 108: 223-32.
    • (2001) J Clin Invest , vol.108 , pp. 223-232
    • Odin, J.A.1    Huebert, R.C.2    Casciola-Rosen, L.3    LaRusso, N.F.4    Rosen, A.5
  • 7
    • 0036830113 scopus 로고    scopus 로고
    • Comprehensive mapping of HLA-A0201-restricted CD8 T-cell epitopes on PDC-E2 in primary biliary cirrhosis
    • Matsumura S, Kita H, He XS, et al. Comprehensive mapping of HLA-A0201-restricted CD8 T-cell epitopes on PDC-E2 in primary biliary cirrhosis. Hepatology 2002; 36: 1125-34.
    • (2002) Hepatology , vol.36 , pp. 1125-1134
    • Matsumura, S.1    Kita, H.2    He, X.S.3
  • 8
    • 0342614209 scopus 로고    scopus 로고
    • Unified nomenclature for the winged helix/forkhead transcription factors
    • Kaestner KH, Knochel W, Martinez DE. Unified nomenclature for the winged helix/forkhead transcription factors. Genes Dev 2000; 14: 142-6.
    • (2000) Genes Dev , vol.14 , pp. 142-146
    • Kaestner, K.H.1    Knochel, W.2    Martinez, D.E.3
  • 9
    • 41849119497 scopus 로고    scopus 로고
    • A brief introduction to FOXOlogy
    • Burgering BM. A brief introduction to FOXOlogy. Oncogene 2008; 27: 2258-62.
    • (2008) Oncogene , vol.27 , pp. 2258-2262
    • Burgering, B.M.1
  • 10
    • 37849041966 scopus 로고    scopus 로고
    • Forkhead transcription factors and cardiovascular biology
    • Papanicolaou KN, Izumiya Y, Walsh K. Forkhead transcription factors and cardiovascular biology. Circ Res 2008; 102: 16-31.
    • (2008) Circ Res , vol.102 , pp. 16-31
    • Papanicolaou, K.N.1    Izumiya, Y.2    Walsh, K.3
  • 11
    • 0038003956 scopus 로고    scopus 로고
    • Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty
    • Burgering BM, Medema RH. Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty. J Leukoc Biol 2003; 73: 689-701.
    • (2003) J Leukoc Biol , vol.73 , pp. 689-701
    • Burgering, B.M.1    Medema, R.H.2
  • 13
    • 0037094096 scopus 로고    scopus 로고
    • The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2
    • Stahl M, Dijkers PF, Kops GJ, et al. The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2. J Immunol 2002; 168: 5024-31.
    • (2002) J Immunol , vol.168 , pp. 5024-5031
    • Stahl, M.1    Dijkers, P.F.2    Kops, G.J.3
  • 14
    • 10744230034 scopus 로고    scopus 로고
    • FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines
    • Sunters A, de Fernandez MS, Stahl M, et al. FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines. J Biol Chem 2003; 278: 49795-805.
    • (2003) J Biol Chem , vol.278 , pp. 49795-49805
    • Sunters, A.1    de Fernandez, M.S.2    Stahl, M.3
  • 15
    • 0032518787 scopus 로고    scopus 로고
    • Bim: a novel member of the Bcl-2 family that promotes apoptosis
    • O'Connor L, Strasser A, O'Reilly LA, et al. Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J 1998; 17: 384-95.
    • (1998) EMBO J , vol.17 , pp. 384-395
    • O'Connor, L.1    Strasser, A.2    O'Reilly, L.A.3
  • 16
    • 68249106060 scopus 로고    scopus 로고
    • BH3-only proteins in apoptosis and beyond: an overview
    • Lomonosova E, Chinnadurai G. BH3-only proteins in apoptosis and beyond: an overview. Oncogene 2008; 27(Suppl 1): S2-19.
    • (2008) Oncogene , vol.27 , Issue.SUPPL 1
    • Lomonosova, E.1    Chinnadurai, G.2
  • 18
    • 0031754499 scopus 로고    scopus 로고
    • Glutathione depletion is associated with decreased Bcl-2 expression and increased apoptosis in cholangiocytes
    • Celli A, Que FG, Gores GJ, LaRusso NF. Glutathione depletion is associated with decreased Bcl-2 expression and increased apoptosis in cholangiocytes. Am J Physiol 1998; 275: G749-57.
    • (1998) Am J Physiol , vol.275
    • Celli, A.1    Que, F.G.2    Gores, G.J.3    LaRusso, N.F.4
  • 19
    • 33846295218 scopus 로고    scopus 로고
    • FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
    • Paik JH, Kollipara R, Chu G, et al. FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell 2007; 128: 309-23.
    • (2007) Cell , vol.128 , pp. 309-323
    • Paik, J.H.1    Kollipara, R.2    Chu, G.3
  • 20
    • 79951828819 scopus 로고    scopus 로고
    • Identification of a mechanism underlying regulation of the anti-angiogenic forkhead transcription factor FoxO1 in cultured endothelial cells and ischemic muscle
    • Milkiewicz M, Roudier E, Doyle JL, et al. Identification of a mechanism underlying regulation of the anti-angiogenic forkhead transcription factor FoxO1 in cultured endothelial cells and ischemic muscle. Am J Pathol 2011; 178: 935-44.
    • (2011) Am J Pathol , vol.178 , pp. 935-944
    • Milkiewicz, M.1    Roudier, E.2    Doyle, J.L.3
  • 21
    • 33847638805 scopus 로고    scopus 로고
    • Soluble apoptosis molecules in primary biliary cirrhosis: analysis and commitment of the Fas and tumour necrosis factor-related apoptosis-inducing ligand systems in comparison with chronic hepatitis C
    • Pelli N, Floreani A, Torre F, et al. Soluble apoptosis molecules in primary biliary cirrhosis: analysis and commitment of the Fas and tumour necrosis factor-related apoptosis-inducing ligand systems in comparison with chronic hepatitis C. Clin Exp Immunol 2007; 148: 85-9.
    • (2007) Clin Exp Immunol , vol.148 , pp. 85-89
    • Pelli, N.1    Floreani, A.2    Torre, F.3
  • 22
    • 33748320925 scopus 로고    scopus 로고
    • Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and SSB/La antibodies in the pathogenesis of congenital heart block
    • Clancy RM, Neufing PJ, Zheng P, et al. Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and SSB/La antibodies in the pathogenesis of congenital heart block. J Clin Invest 2006; 116: 2413-22.
    • (2006) J Clin Invest , vol.116 , pp. 2413-2422
    • Clancy, R.M.1    Neufing, P.J.2    Zheng, P.3
  • 23
    • 0031884870 scopus 로고    scopus 로고
    • High levels of circulating early apoptic peripheral blood mononuclear cells in systemic lupus erythematosus
    • Perniok A, Wedekind F, Herrmann M, Specker C, Schneider M. High levels of circulating early apoptic peripheral blood mononuclear cells in systemic lupus erythematosus. Lupus 1998; 7: 113-8.
    • (1998) Lupus , vol.7 , pp. 113-118
    • Perniok, A.1    Wedekind, F.2    Herrmann, M.3    Specker, C.4    Schneider, M.5
  • 24
    • 0034771935 scopus 로고    scopus 로고
    • Role of apoptosis in development of primary biliary cirrhosis
    • Marzioni M, Glaser SS, Alpini G, LeSage GD. Role of apoptosis in development of primary biliary cirrhosis. Dig Liver Dis 2001; 33: 531-3.
    • (2001) Dig Liver Dis , vol.33 , pp. 531-533
    • Marzioni, M.1    Glaser, S.S.2    Alpini, G.3    LeSage, G.D.4
  • 25
    • 0033104996 scopus 로고    scopus 로고
    • The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
    • Puthalakath H, Huang DC, O'Reilly LA, King SM, Strasser A. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol Cell 1999; 3: 287-96.
    • (1999) Mol Cell , vol.3 , pp. 287-296
    • Puthalakath, H.1    Huang, D.C.2    O'Reilly, L.A.3    King, S.M.4    Strasser, A.5
  • 26
    • 43449132366 scopus 로고    scopus 로고
    • Multisite phosphorylation regulates Bim stability and apoptotic activity
    • Hubner A, Barrett T, Flavell RA, Davis RJ. Multisite phosphorylation regulates Bim stability and apoptotic activity. Mol Cell 2008; 30: 415-25.
    • (2008) Mol Cell , vol.30 , pp. 415-425
    • Hubner, A.1    Barrett, T.2    Flavell, R.A.3    Davis, R.J.4
  • 27
    • 34848861130 scopus 로고    scopus 로고
    • Transcriptional Regulation of Bim by FoxO3A Mediates Hepatocyte Lipoapoptosis
    • Barreyro FJ, Kobayashi S, Bronk SF, et al. Transcriptional Regulation of Bim by FoxO3A Mediates Hepatocyte Lipoapoptosis. J Biol Chem 2007; 282: 27141-54.
    • (2007) J Biol Chem , vol.282 , pp. 27141-27154
    • Barreyro, F.J.1    Kobayashi, S.2    Bronk, S.F.3
  • 28
    • 0037017396 scopus 로고    scopus 로고
    • FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity
    • Dijkers PF, Birkenkamp KU, Lam EW, et al. FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity. J Cell Biol 2002; 156: 531-42.
    • (2002) J Cell Biol , vol.156 , pp. 531-542
    • Dijkers, P.F.1    Birkenkamp, K.U.2    Lam, E.W.3
  • 29
    • 0034609737 scopus 로고    scopus 로고
    • Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
    • Dijkers PF, Medema RH, Lammers JW, Koenderman L, Coffer PJ. Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr Biol 2000; 10: 1201-4.
    • (2000) Curr Biol , vol.10 , pp. 1201-1204
    • Dijkers, P.F.1    Medema, R.H.2    Lammers, J.W.3    Koenderman, L.4    Coffer, P.J.5
  • 30
    • 0036850972 scopus 로고    scopus 로고
    • Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons
    • Linseman DA, Phelps RA, Bouchard RJ, et al. Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons. J Neurosci 2002; 22: 9287-97.
    • (2002) J Neurosci , vol.22 , pp. 9287-9297
    • Linseman, D.A.1    Phelps, R.A.2    Bouchard, R.J.3
  • 31
    • 0042477712 scopus 로고    scopus 로고
    • FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
    • Gilley J, Coffer PJ, Ham J. FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. J Cell Biol 2003; 162: 613-22.
    • (2003) J Cell Biol , vol.162 , pp. 613-622
    • Gilley, J.1    Coffer, P.J.2    Ham, J.3
  • 32
    • 33846294435 scopus 로고    scopus 로고
    • FoxOs in tumor suppression and stem cell maintenance
    • Arden KC. FoxOs in tumor suppression and stem cell maintenance. Cell 2007; 128: 235-7.
    • (2007) Cell , vol.128 , pp. 235-237
    • Arden, K.C.1
  • 33
    • 0028143211 scopus 로고
    • Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
    • Elliott MJ, Maini RN, Feldmann M, et al. Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 1994; 344: 1105-10.
    • (1994) Lancet , vol.344 , pp. 1105-1110
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3
  • 34
    • 0030954732 scopus 로고    scopus 로고
    • A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group
    • Targan SR, Hanauer SB, van Deventer SJ, et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med 1997; 337: 1029-35.
    • (1997) N Engl J Med , vol.337 , pp. 1029-1035
    • Targan, S.R.1    Hanauer, S.B.2    van Deventer, S.J.3


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