메뉴 건너뛰기




Volumn 8, Issue 1, 2013, Pages

The Induction of microRNA-16 in Colon Cancer Cells by Protein Arginine Deiminase Inhibition Causes a p53-Dependent Cell Cycle Arrest

Author keywords

[No Author keywords available]

Indexed keywords

CHLOR AMIDINE; CYCLIN D1; CYCLIN D2; CYCLIN D3; CYCLIN E; CYCLIN E1; ENZYME INHIBITOR; MICRORNA 16; PROTEIN ARGININE DEIMINASE; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 84872156834     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053791     Document Type: Article
Times cited : (38)

References (52)
  • 1
    • 60549084383 scopus 로고    scopus 로고
    • Increased PADI4 expression in blood and tissues of patients with malignant tumors
    • Chang X, Han J, Pang L, Zhao Y, Yang Y, et al. (2009) Increased PADI4 expression in blood and tissues of patients with malignant tumors. BMC Cancer 9: 40.
    • (2009) BMC Cancer , vol.9 , pp. 40
    • Chang, X.1    Han, J.2    Pang, L.3    Zhao, Y.4    Yang, Y.5
  • 3
    • 0242720407 scopus 로고    scopus 로고
    • PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease
    • Vossenaar ER, Zendman AJ, van Venrooij WJ, Pruijn GJ, (2003) PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease. Bioessays 25: 1106-1118.
    • (2003) Bioessays , vol.25 , pp. 1106-1118
    • Vossenaar, E.R.1    Zendman, A.J.2    van Venrooij, W.J.3    Pruijn, G.J.4
  • 4
    • 79957951714 scopus 로고    scopus 로고
    • Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor
    • Chumanevich AA, Causey CP, Knuckley BA, Jones JE, Poudyal D, et al. (2011) Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor. Am 300: G929-938.
    • (2011) Am , vol.300
    • Chumanevich, A.A.1    Causey, C.P.2    Knuckley, B.A.3    Jones, J.E.4    Poudyal, D.5
  • 6
    • 33644830015 scopus 로고    scopus 로고
    • Expression of peptidylarginine deiminase type 4 (PAD4) in various tumors
    • Chang X, Han J, (2006) Expression of peptidylarginine deiminase type 4 (PAD4) in various tumors. Mol Carcinog 45: 183-196.
    • (2006) Mol Carcinog , vol.45 , pp. 183-196
    • Chang, X.1    Han, J.2
  • 7
    • 84867386515 scopus 로고    scopus 로고
    • Potential role of peptidylarginine deiminase enzymes and protein citrullination in cancer pathogenesis
    • Mohanan S, Cherrington BD, Horibata S, McElwee JL, Thompson PR, et al. (2012) Potential role of peptidylarginine deiminase enzymes and protein citrullination in cancer pathogenesis. Biochem Res Int 2012: 895343.
    • (2012) Biochem Res Int , vol.2012 , pp. 895343
    • Mohanan, S.1    Cherrington, B.D.2    Horibata, S.3    McElwee, J.L.4    Thompson, P.R.5
  • 8
    • 79951578893 scopus 로고    scopus 로고
    • Protein arginine deiminase 4: a target for an epigenetic cancer therapy
    • Slack JL, Causey CP, Thompson PR, (2011) Protein arginine deiminase 4: a target for an epigenetic cancer therapy. Cell Mol Life Sci 68: 709-720.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 709-720
    • Slack, J.L.1    Causey, C.P.2    Thompson, P.R.3
  • 9
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 10
    • 11844262661 scopus 로고    scopus 로고
    • Phylogenetic shadowing and computational identification of human microRNA genes
    • Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, et al. (2005) Phylogenetic shadowing and computational identification of human microRNA genes. Cell 120: 21-24.
    • (2005) Cell , vol.120 , pp. 21-24
    • Berezikov, E.1    Guryev, V.2    van de Belt, J.3    Wienholds, E.4    Plasterk, R.H.5
  • 11
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP, (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 12
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, et al. (2002) Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 99: 15524-15529.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3    Bichi, R.4    Zupo, S.5
  • 13
    • 67650422613 scopus 로고    scopus 로고
    • miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer
    • Bandi N, Zbinden S, Gugger M, Arnold M, Kocher V, et al. (2009) miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer. Cancer Res 69: 5553-5559.
    • (2009) Cancer Res , vol.69 , pp. 5553-5559
    • Bandi, N.1    Zbinden, S.2    Gugger, M.3    Arnold, M.4    Kocher, V.5
  • 14
    • 73649116987 scopus 로고    scopus 로고
    • The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia
    • Klein U, Lia M, Crespo M, Siegel R, Shen Q, et al. (2010) The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia. Cancer Cell 17: 28-40.
    • (2010) Cancer Cell , vol.17 , pp. 28-40
    • Klein, U.1    Lia, M.2    Crespo, M.3    Siegel, R.4    Shen, Q.5
  • 15
    • 55549114664 scopus 로고    scopus 로고
    • The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities
    • Bonci D, Coppola V, Musumeci M, Addario A, Giuffrida R, et al. (2008) The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. Nat Med 14: 1271-1277.
    • (2008) Nat Med , vol.14 , pp. 1271-1277
    • Bonci, D.1    Coppola, V.2    Musumeci, M.3    Addario, A.4    Giuffrida, R.5
  • 16
    • 84860788476 scopus 로고    scopus 로고
    • Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development
    • Rivas MA, Venturutti L, Huang YW, Schillaci R, Huang TH, et al. (2012) Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development. Breast Cancer Res 14: R77.
    • (2012) Breast Cancer Res , vol.14
    • Rivas, M.A.1    Venturutti, L.2    Huang, Y.W.3    Schillaci, R.4    Huang, T.H.5
  • 17
    • 79955644463 scopus 로고    scopus 로고
    • The miR-15a-miR-16-1 locus is homozygously deleted in a subset of prostate cancers
    • doi: 410.1002/gcc.20873
    • Porkka KP, Ogg EL, Saramaki OR, Vessella RL, Pukkila H, et al. (2011) The miR-15a-miR-16-1 locus is homozygously deleted in a subset of prostate cancers. Genes Chromosomes Cancer 50: 499-509 doi:410.1002/gcc.20873.
    • (2011) Genes Chromosomes Cancer , vol.50 , pp. 499-509
    • Porkka, K.P.1    Ogg, E.L.2    Saramaki, O.R.3    Vessella, R.L.4    Pukkila, H.5
  • 19
    • 84866436241 scopus 로고    scopus 로고
    • miR-15a and miR-16-1 downregulate CCND1 and induce apoptosis and cell cycle arrest in osteosarcoma
    • doi: 1710.3892/or.2012.1995
    • Cai CK, Zhao GY, Tian LY, Liu L, Yan K, et al. (2012) miR-15a and miR-16-1 downregulate CCND1 and induce apoptosis and cell cycle arrest in osteosarcoma. Oncol Rep 28: 1764-1770 doi: 1710.3892/or.2012.1995.
    • (2012) Oncol Rep , vol.28 , pp. 1764-1770
    • Cai, C.K.1    Zhao, G.Y.2    Tian, L.Y.3    Liu, L.4    Yan, K.5
  • 20
    • 33947224690 scopus 로고    scopus 로고
    • Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression
    • Linsley PS, Schelter J, Burchard J, Kibukawa M, Martin MM, et al. (2007) Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression. Mol Cell Biol 27: 2240-2252.
    • (2007) Mol Cell Biol , vol.27 , pp. 2240-2252
    • Linsley, P.S.1    Schelter, J.2    Burchard, J.3    Kibukawa, M.4    Martin, M.M.5
  • 21
    • 80053000096 scopus 로고    scopus 로고
    • MicroRNA destabilization enables dynamic regulation of the miR-16 family in response to cell-cycle changes
    • Rissland OS, Hong SJ, Bartel DP, (2011) MicroRNA destabilization enables dynamic regulation of the miR-16 family in response to cell-cycle changes. Mol Cell 43: 993-1004.
    • (2011) Mol Cell , vol.43 , pp. 993-1004
    • Rissland, O.S.1    Hong, S.J.2    Bartel, D.P.3
  • 22
    • 79959702659 scopus 로고    scopus 로고
    • Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro
    • doi: 110.1038/bjc.2011.1190
    • Wu G, Yu F, Xiao Z, Xu K, Xu J, et al. (2011) Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro. Br J Cancer 105: 146-153 doi: 110.1038/bjc.2011.1190.
    • (2011) Br J Cancer , vol.105 , pp. 146-153
    • Wu, G.1    Yu, F.2    Xiao, Z.3    Xu, K.4    Xu, J.5
  • 23
    • 79954459249 scopus 로고    scopus 로고
    • MiR-15 and miR-16 are direct transcriptional targets of E2F1 that limit E2F-induced proliferation by targeting cyclin
    • Ofir M, Hacohen D, Ginsberg D, (2011) MiR-15 and miR-16 are direct transcriptional targets of E2F1 that limit E2F-induced proliferation by targeting cyclin E. Mol Cancer Res. 9: 440-447.
    • (2011) E. Mol Cancer Res , vol.9 , pp. 440-447
    • Ofir, M.1    Hacohen, D.2    Ginsberg, D.3
  • 24
    • 73449129760 scopus 로고    scopus 로고
    • Down-regulation of the cyclin E1 oncogene expression by microRNA-16-1 induces cell cycle arrest in human cancer cells
    • Wang F, Fu XD, Zhou Y, Zhang Y, (2009) Down-regulation of the cyclin E1 oncogene expression by microRNA-16-1 induces cell cycle arrest in human cancer cells. BMB Rep 42: 725-730.
    • (2009) BMB Rep , vol.42 , pp. 725-730
    • Wang, F.1    Fu, X.D.2    Zhou, Y.3    Zhang, Y.4
  • 25
    • 74149083873 scopus 로고    scopus 로고
    • Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes
    • Takeshita F, Patrawala L, Osaki M, Takahashi RU, Yamamoto Y, et al. (2010) Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. Mol Ther 18: 181-187.
    • (2010) Mol Ther , vol.18 , pp. 181-187
    • Takeshita, F.1    Patrawala, L.2    Osaki, M.3    Takahashi, R.U.4    Yamamoto, Y.5
  • 26
    • 70349456537 scopus 로고    scopus 로고
    • DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1
    • Lerner M, Harada M, Loven J, Castro J, Davis Z, et al. (2009) DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1. Exp Cell Res 315: 2941-2952.
    • (2009) Exp Cell Res , vol.315 , pp. 2941-2952
    • Lerner, M.1    Harada, M.2    Loven, J.3    Castro, J.4    Davis, Z.5
  • 27
    • 47949123469 scopus 로고    scopus 로고
    • Regulation of p53 target gene expression by peptidylarginine deiminase 4
    • Epub 2008 May 4727
    • Li P, Yao H, Zhang Z, Li M, Luo Y, et al. (2008) Regulation of p53 target gene expression by peptidylarginine deiminase 4. Mol Cell Biol 28: 4745-4758. Epub 2008 May 4727.
    • (2008) Mol Cell Biol , vol.28 , pp. 4745-4758
    • Li, P.1    Yao, H.2    Zhang, Z.3    Li, M.4    Luo, Y.5
  • 28
    • 33749359452 scopus 로고    scopus 로고
    • Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization
    • Luo Y, Arita K, Bhatia M, Knuckley B, Lee YH, et al. (2006) Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization. Biochemistry 45: 11727-11736.
    • (2006) Biochemistry , vol.45 , pp. 11727-11736
    • Luo, Y.1    Arita, K.2    Bhatia, M.3    Knuckley, B.4    Lee, Y.H.5
  • 29
    • 44649174340 scopus 로고    scopus 로고
    • An improved synthesis of haloaceteamidine-based inactivators of protein arginine deiminase 4 (PAD4)
    • Causey CP, Thompson PR, (2008) An improved synthesis of haloaceteamidine-based inactivators of protein arginine deiminase 4 (PAD4). Tetrahedron Lett 49: 4383-4385.
    • (2008) Tetrahedron Lett , vol.49 , pp. 4383-4385
    • Causey, C.P.1    Thompson, P.R.2
  • 30
    • 35148818742 scopus 로고    scopus 로고
    • Nitric oxide inactivates the retinoblastoma pathway in chronic inflammation
    • Ying L, Hofseth AB, Browning DD, Nagarkatti M, Nagarkatti PS, et al. (2007) Nitric oxide inactivates the retinoblastoma pathway in chronic inflammation. Cancer Res 67: 9286-9293.
    • (2007) Cancer Res , vol.67 , pp. 9286-9293
    • Ying, L.1    Hofseth, A.B.2    Browning, D.D.3    Nagarkatti, M.4    Nagarkatti, P.S.5
  • 31
    • 79952290501 scopus 로고    scopus 로고
    • MicroRNA in colorectal cancer: from benchtop to bedside
    • Wu WK, Law PT, Lee CW, Cho CH, Fan D, et al. (2011) MicroRNA in colorectal cancer: from benchtop to bedside. Carcinogenesis 32: 247-253.
    • (2011) Carcinogenesis , vol.32 , pp. 247-253
    • Wu, W.K.1    Law, P.T.2    Lee, C.W.3    Cho, C.H.4    Fan, D.5
  • 33
    • 52649088391 scopus 로고    scopus 로고
    • miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes
    • Liu Q, Fu H, Sun F, Zhang H, Tie Y, et al. (2008) miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes. Nucleic Acids Res 36: 5391-5404.
    • (2008) Nucleic Acids Res , vol.36 , pp. 5391-5404
    • Liu, Q.1    Fu, H.2    Sun, F.3    Zhang, H.4    Tie, Y.5
  • 34
    • 84860762133 scopus 로고    scopus 로고
    • Evidence for cell cycle suppression and microRNA regulation of cyclin D1 during anoxia exposure in turtles
    • Biggar KK, Storey KB, (2012) Evidence for cell cycle suppression and microRNA regulation of cyclin D1 during anoxia exposure in turtles. Cell Cycle 11: 1705-1713.
    • (2012) Cell Cycle , vol.11 , pp. 1705-1713
    • Biggar, K.K.1    Storey, K.B.2
  • 35
    • 78149416322 scopus 로고    scopus 로고
    • MicroRNA mir-16 is anti-proliferative in enterocytes and exhibits diurnal rhythmicity in intestinal crypts
    • Balakrishnan A, Stearns AT, Park PJ, Dreyfuss JM, Ashley SW, et al. (2010) MicroRNA mir-16 is anti-proliferative in enterocytes and exhibits diurnal rhythmicity in intestinal crypts. Exp Cell Res 316: 3512-3521.
    • (2010) Exp Cell Res , vol.316 , pp. 3512-3521
    • Balakrishnan, A.1    Stearns, A.T.2    Park, P.J.3    Dreyfuss, J.M.4    Ashley, S.W.5
  • 36
    • 70349783724 scopus 로고    scopus 로고
    • Effects of upregulated expression of microRNA-16 on biological properties of culture-activated hepatic stellate cells
    • Guo CJ, Pan Q, Jiang B, Chen GY, Li DG, (2009) Effects of upregulated expression of microRNA-16 on biological properties of culture-activated hepatic stellate cells. Apoptosis 14: 1331-1340.
    • (2009) Apoptosis , vol.14 , pp. 1331-1340
    • Guo, C.J.1    Pan, Q.2    Jiang, B.3    Chen, G.Y.4    Li, D.G.5
  • 37
    • 0019436684 scopus 로고
    • Properties of peptidylarginine deiminase from the epidermis of newborn rats
    • Fujisaki M, Sugawara K, (1981) Properties of peptidylarginine deiminase from the epidermis of newborn rats. J Biochem 89: 257-263.
    • (1981) J Biochem , vol.89 , pp. 257-263
    • Fujisaki, M.1    Sugawara, K.2
  • 38
    • 77957770455 scopus 로고    scopus 로고
    • Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase
    • Chumanevich AA, Poudyal D, Cui X, Davis T, Wood PA, et al. (2010) Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase. Carcinogenesis 31: 1787-1793.
    • (2010) Carcinogenesis , vol.31 , pp. 1787-1793
    • Chumanevich, A.A.1    Poudyal, D.2    Cui, X.3    Davis, T.4    Wood, P.A.5
  • 39
    • 77950820267 scopus 로고    scopus 로고
    • Resveratrol suppresses colitis and colon cancer associated with colitis
    • Cui X, Jin Y, Hofseth AB, Pena E, Habiger J, et al. (2010) Resveratrol suppresses colitis and colon cancer associated with colitis. Cancer Prev Res 3: 549-559.
    • (2010) Cancer Prev Res , vol.3 , pp. 549-559
    • Cui, X.1    Jin, Y.2    Hofseth, A.B.3    Pena, E.4    Habiger, J.5
  • 41
    • 0023911563 scopus 로고
    • Colon cancer in ulcerative colitis
    • Ransohoff DF, (1988) Colon cancer in ulcerative colitis. Gastroenterology 94: 1089-1091.
    • (1988) Gastroenterology , vol.94 , pp. 1089-1091
    • Ransohoff, D.F.1
  • 42
    • 34548316885 scopus 로고    scopus 로고
    • Dysplasia and cancer in inflammatory bowel disease 10 years after diagnosis: results of a population-based European collaborative follow-up study
    • Katsanos KH, Vermeire S, Christodoulou DK, Riis L, Wolters F, et al. (2007) Dysplasia and cancer in inflammatory bowel disease 10 years after diagnosis: results of a population-based European collaborative follow-up study. Digestion 75: 113-121.
    • (2007) Digestion , vol.75 , pp. 113-121
    • Katsanos, K.H.1    Vermeire, S.2    Christodoulou, D.K.3    Riis, L.4    Wolters, F.5
  • 43
    • 79953183602 scopus 로고    scopus 로고
    • A microarray-based approach identifies ADP ribosylation factor-like protein 2 as a target of microRNA-16
    • Wang K, Li P, Dong Y, Cai X, Hou D, et al. (2011) A microarray-based approach identifies ADP ribosylation factor-like protein 2 as a target of microRNA-16. J Biol Chem 286: 9468-9476.
    • (2011) J Biol Chem , vol.286 , pp. 9468-9476
    • Wang, K.1    Li, P.2    Dong, Y.3    Cai, X.4    Hou, D.5
  • 44
    • 67651149479 scopus 로고    scopus 로고
    • MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response
    • Pothof J, Verkaik NS, Van IW, Wiemer EA, Ta VT, et al. (2009) MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response. Embo J 28: 2090-2099.
    • (2009) Embo J , vol.28 , pp. 2090-2099
    • Pothof, J.1    Verkaik, N.S.2    Van, I.W.3    Wiemer, E.A.4    Ta, V.T.5
  • 45
    • 77953258110 scopus 로고    scopus 로고
    • Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3
    • Knuckley B, Causey CP, Jones JE, Bhatia M, Dreyton CJ, et al. (2010) Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3. Biochemistry 49: 4852-4863.
    • (2010) Biochemistry , vol.49 , pp. 4852-4863
    • Knuckley, B.1    Causey, C.P.2    Jones, J.E.3    Bhatia, M.4    Dreyton, C.J.5
  • 46
  • 47
    • 84864224456 scopus 로고    scopus 로고
    • Potential role for PAD2 in gene regulation in breast cancer cells
    • doi: 41210.41371/journal.pone.0041242
    • Cherrington BD, Zhang X, McElwee JL, Morency E, Anguish LJ, et al. (2012) Potential role for PAD2 in gene regulation in breast cancer cells. PLoS One 7: e41242 doi: 41210.41371/journal.pone.0041242.
    • (2012) PLoS One , vol.7
    • Cherrington, B.D.1    Zhang, X.2    McElwee, J.L.3    Morency, E.4    Anguish, L.J.5
  • 48
    • 77952954497 scopus 로고    scopus 로고
    • Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression
    • Li P, Wang D, Yao H, Doret P, Hao G, et al. (2010) Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression. Oncogene 29: 3153-3162.
    • (2010) Oncogene , vol.29 , pp. 3153-3162
    • Li, P.1    Wang, D.2    Yao, H.3    Doret, P.4    Hao, G.5
  • 49
    • 5044228483 scopus 로고    scopus 로고
    • Human PAD4 regulates histone arginine methylation levels via demethylimination
    • Wang Y, Wysocka J, Sayegh J, Lee YH, Perlin JR, et al. (2004) Human PAD4 regulates histone arginine methylation levels via demethylimination. Science 306: 279-283.
    • (2004) Science , vol.306 , pp. 279-283
    • Wang, Y.1    Wysocka, J.2    Sayegh, J.3    Lee, Y.H.4    Perlin, J.R.5
  • 51
    • 79955765048 scopus 로고    scopus 로고
    • Citrullination of inhibitor of growth 4 (ING4) by peptidylarginine deminase 4 (PAD4) disrupts the interaction between ING4 and p53
    • Guo Q, Fast W, (2011) Citrullination of inhibitor of growth 4 (ING4) by peptidylarginine deminase 4 (PAD4) disrupts the interaction between ING4 and p53. J Biol Chem 286: 17069-17078.
    • (2011) J Biol Chem , vol.286 , pp. 17069-17078
    • Guo, Q.1    Fast, W.2
  • 52
    • 79955054710 scopus 로고    scopus 로고
    • Gain of function of mutant p53 by coaggregation with multiple tumor suppressors
    • Xu J, Reumers J, Couceiro JR, De Smet F, Gallardo R, et al. (2011) Gain of function of mutant p53 by coaggregation with multiple tumor suppressors. Nat Chem Biol 7: 285-295.
    • (2011) Nat Chem Biol , vol.7 , pp. 285-295
    • Xu, J.1    Reumers, J.2    Couceiro, J.R.3    De Smet, F.4    Gallardo, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.