High-dose dietary exposure of mice to perfluorooctanoate or perfluorooctane sulfonate exerts toxic effects on myeloid and B-lymphoid cells in the bone marrow and these effects are partially dependent on reduced food consumption

Food and Chemical Toxicology

Volumn 50, Issue 9, 2012, Pages 2955-2963

  Qazi, Mousumi Rahman ^a   Dean Nelson, B ^a   DePierre, Joseph W ^a   Abedi Valugerdi, Manuchehr ^a,b,c  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b ImmunoBioTox (IBT) AB   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

B lymphoid cells; Bone marrow; Food restriction; Myeloid cells; Perfluorooctane sulfonate; Perfluorooctanoate

Indexed keywords

PERFLUOROOCTANESULFONIC ACID; PERFLUOROOCTANOIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATROPHY; B LYMPHOID CELL; BONE MARROW CELL; BONE MARROW TOXICITY; CELL COUNT; CELL MATURATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIET RESTRICTION; DIETARY INTAKE; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNOTOXICITY; LYMPHOID CELL; MALE; MOUSE; NONHUMAN; PRE B LYMPHOCYTE; SPLEEN ATROPHY; SPLEEN DISEASE; THYMUS ATROPHY;

ALKANESULFONIC ACIDS; ANIMALS; B-LYMPHOCYTES; BODY WEIGHT; BONE MARROW CELLS; CAPRYLATES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEEDING BEHAVIOR; FLOW CYTOMETRY; FLUOROCARBONS; MALE; MICE; MICE, INBRED C57BL;

ANIMALIA; MUS;

EID: 84864053605     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.06.023     Document Type: Article

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