Long-term oral administration of capsicum baccatum extracts does not alter behavioral, hematological, and metabolic parameters in CF1 mice

Evidence-based Complementary and Alternative Medicine

Volumn 2012, Issue , 2012, Pages

  Zimmer, Aline Rigon ^a   Leonardi, Bianca ^a   Zimmer, Eduardo Rigon ^a   Kalinine, Eduardo ^a   De Souza, Diogo Onofre ^a   Portela, Luis Valmor ^a   Gosmann, Grace ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; CAPSICUM BACCATUM EXTRACT; CREATININE; GALLIC ACID; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LACTATE DEHYDROGENASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLANT EXTRACT; QUERCETIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANXIETY DISORDER; ARTICLE; BODY WEIGHT; CAPSICUM BACCATUM; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFICACY; DRUG SAFETY; ERYTHROCYTE COUNT; GLUCOSE HOMEOSTASIS; HEMATOCRIT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFLAMMATION; LACTATE DEHYDROGENASE BLOOD LEVEL; LEUKOCYTE COUNT; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; MEDICINAL PLANT; MOUSE; NONHUMAN; ORGAN WEIGHT; OXIDATIVE STRESS; PHYTOCHEMISTRY; PRIORITY JOURNAL; TASK PERFORMANCE; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 84872151890     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2012/196358     Document Type: Article

References (27)

1. Govindarajan V. S., Capsicum production, technology, chemistry, and quality. Part 1: History, botany, cultivation, and primary processing. Critical Reviews in Food Science and Nutrition 1985 22 2 109 176 2-s2.0-0021777653
2. Pino J., González M., Ceballos L., Centurión-Yah A. R., Trujillo-Aguirre J., Latournerie-Moreno L., Sauri-Duch E., Characterization of total capsaicinoids, colour and volatile compounds of Habanero chilli pepper (Capsicum chinense Jack.) cultivars grown in Yucatan. Food Chemistry 2007 104 4 1682 1686 2-s2.0-34249327307 10.1016/j.foodchem.2006.12.067 (Pubitemid 46805122)
3. Ochi T., Takaishi Y., Kogure K., Yamauti I., Antioxidant activity of a new capsaicin derivative from Capsicum annuum. Journal of Natural Products 2003 66 8 1094 1096 2-s2.0-0041420954 10.1021/np020465y (Pubitemid 37034044)
4. Topuz A., Ozdemir F., Assessment of carotenoids, capsaicinoids and ascorbic acid composition of some selected pepper cultivars (Capsicum annuum L.) grown in Turkey. Journal of Food Composition and Analysis 2007 20 7 596 602 2-s2.0-34447283286 10.1016/j.jfca.2007.03.007 (Pubitemid 47040635)
5. Materska M., Perucka I., Antioxidant activity of the main phenolic compounds isolated from hot pepper fruit (Capsicum annuum L.). Journal of Agricultural and Food Chemistry 2005 53 5 1750 1756 2-s2.0-14744278639 10.1021/jf035331k (Pubitemid 40326270)
6. Menichini F., Tundis R., Bonesi M., Loizzo M. R., Conforti F., Statti G., De Cindio B., Houghton P. J., Menichini F., The influence of fruit ripening on the phytochemical content and biological activity of Capsicum chinense Jacq. cv Habanero. Food Chemistry 2009 114 2 553 560 2-s2.0-58749086384 10.1016/j.foodchem.2008.09.086
7. Muller A. P., Gnoatto J., Moreira J. D., Zimmer E. R., Haas C. B., Lulhier F., Perry M. L., Souza D. O., Torres-Aleman I., Portela L. V., Exercise increases insulin signaling in the hippocampus: physiological effects and pharmacological impact of intracerebroventricular insulin administration in mice. Hippocampus 2011 21 1082 1092
8. Barnes J J., Anderson L. A., Phillipson J. D., Herbal Medicines 2007 3rd London, UK Pharmaceutical Press
9. Ahuja K. D. K., Robertson I. K., Geraghty D. P., Ball M. J., The effect of 4-week chilli supplementation on metabolic and arterial function in humans. European Journal of Clinical Nutrition 2007 61 3 326 333 2-s2.0-33847687180 10.1038/sj.ejcn.1602517 (Pubitemid 46358771)
10. Aizawa K., Inakuma T., Dietary capsanthin, the main carotenoid in paprika (Capsicum annuum), alters plasma high-density lipoprotein-cholesterol levels and hepatic gene expression in rats. British Journal of Nutrition 2009 102 12 1760 1766 2-s2.0-74949131296 10.1017/S0007114509991309
11. Liu Y., Nair M. G., Capsaicinoids in the hottest pepper Bhut Jolokia and its antioxidant and antiinflammatory activities. Natural Product Communications 2010 5 1 91 94 2-s2.0-77950493222
12. Ranilla L. G., Kwon Y. I., Apostolidis E., Shetty K., Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used medicinal plants, herbs and spices in Latin America. Bioresource Technology 2010 101 12 4676 4689 2-s2.0-77949264278 10.1016/j.biortech.2010.01.093
13. Srinivasan K., Spices as influencers of body metabolism: an overview of three decades of research. Food Research International 2005 38 1 77 86 2-s2.0-7444222903 10.1016/j.foodres.2004.09.001 (Pubitemid 39444470)
14. Altman R. D., Barthel H. R., Topical therapies for osteoarthritis. Drugs 2011 71 10 1259 1279 2-s2.0-79960519468 10.2165/11592550-000000000-00000
15. Donofrio P., Walker F., Hunt V., Tandan R., Fries T., Lewis G., Ramamurthy S., Mireles J. A., Hoffman J., Scheffler N., Sheitel P., Campbell S., Wendt J., Thomas J., Kurent J., Whitehouse F., Basha K., Dailey G., Muchmore D., Treatment of painful diabetic neuropathy with topical capsaicin: a multicenter, double-blind, vehicle-controlled study. Archives of Internal Medicine 1991 151 11 2225 2229 2-s2.0-0025841729 10.1001/archinte.151.11.2225
16. Kappel V. D., Costa G. M., Scola G., Silva F. A., Landell M. F., Valente P., Souza D. G., Vanz D. C., Reginatto F. H., Moreira J. C. F., Phenolic content and antioxidant and antimicrobial properties of fruits of Capsicum baccatum L. var. pendulum at different maturity stages. Journal of Medicinal Food 2008 11 2 267 274 2-s2.0-46749104108 10.1089/jmf.2007.626 (Pubitemid 351948183)
17. Kollmannsberger H., Rodríguez-Burruezo A., Nitz S., Nuez F., Volatile and capsaicinoid composition of ají (Capsicum baccatum) and rocoto (Capsicum pubescens), two Andean species of chile peppers. Journal of the Science of Food and Agriculture 2011 91 9 1598 1611 2-s2.0-79958756493 10.1002/jsfa.4354
18. Rodríguez-Burruezo A., González-Mas M. C., Nuez F., Carotenoid composition and vitamin A value in ají(Capsicum baccatum L.) and rocoto (C. pubescens R. & P.), 2 pepper species from the andean region. Journal of Food Science 2010 75 8 S446 S453 2-s2.0-77958582999 10.1111/j.1750-3841.2010.01795.x
19. Spiller F., Alves M. K., Vieira S. M., Carvalho T. A., Leite C. E., Lunardelli A., Poloni J. A., Cunha F. Q., De Oliveira J. R., Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation. Journal of Pharmacy and Pharmacology 2008 60 4 473 478 2-s2.0-41849147899 10.1211/jpp.60.4.0010 (Pubitemid 351500558)
20. Zimmer A. R., Leonardi B., Miron D., Schapoval E., de Oliveira J. R., Gosmann G., Antioxidant and anti-inflammatory properties of Capsicum baccatum: from traditional use to scientific approach. Journal of Ethnopharmacology 2012 139 228 233
21. Chuah L. O., Yeap S. K., Ho W. Y., Beh B. K., Alitheen N. B., In vitro and in vivo toxicity of garcinia or hydroxycitric acid: a review. Evidence-Based Complementary and Alternative Medicine 2012 2012 12 197920 10.1155/2012/197920
22. Leasure J. L., Decker L., Social isolation prevents exercise-induced proliferation of hippocampal progenitor cells in female rats. Hippocampus 2009 19 10 907 912 2-s2.0-70149121742 10.1002/hipo.20563
23. Whimbey A. E., Denenberg V. H., Two independent behavioral dimensions in open-field performance. Journal of Comparative and Physiological Psychology 1967 63 3 500 504 2-s2.0-0014100525 10.1037/h0024620
24. Prut L., Belzung C., The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review. European Journal of Pharmacology 2003 463 1-3 3 33 2-s2.0-0037470154 10.1016/S0014-2999(03)01272-X (Pubitemid 36205070)
25. Pellow S., Chopin P., File S. E., Briley M., Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. Journal of Neuroscience Methods 1985 14 3 149 167 2-s2.0-0022374863 (Pubitemid 16239568)
26. Parekh P. I., Petro A. E., Tiller J. M., Feinglos M. N., Surwit R. S., Reversal of diet-induced obesity and diabetes in C57BL/6J mice. Metabolism 1998 47 9 1089 1096 2-s2.0-0031782573 10.1016/S0026-0495(98)90283-9 (Pubitemid 28428014)
27. Kazlauckas V., Pagnussat N., Mioranzza S., Kalinine E., Nunes F., Pettenuzzo L., Souza D. O., Portela L. V., Porciúncula L. O., Lara D. R., Enriched environment effects on behavior, memory and BDNF in low and high exploratory mice. Physiology and Behavior 2011 102 5 475 480 2-s2.0-78651494260 10.1016/j.physbeh.2010.12.025