CNS demyelination in fibrodysplasia ossificans progressiva

Journal of Neurology

Volumn 259, Issue 12, 2012, Pages 2644-2655

  Kan, Lixin ^a   Kitterman, Joseph A ^b   Procissi, Daniele ^c   Chakkalakal, Salin ^a   Peng, Chian Yu ^d   McGuire, Tammy L ^d   Goldsby, Robert E ^e   Pignolo, Robert J ^d   Shore, Eileen M ^a   Kaplan, Frederick S ^d   Kessler, John A ^d  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Vanda Pharmaceuticals   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

ACVR1 ALK2; Animal model; Bone morphogenetic protein (BMP); Demyelination; Fibrodysplasia ossificans progressiva (FOP); Magnetic resonance imaging (MRI)

Indexed keywords

ACVR1 PROTEIN; BONE MORPHOGENETIC PROTEIN 4; NEURON SPECIFIC ENOLASE; PROCOLLAGEN C PROTEINASE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; CASE REPORT; CHILD; CONTROLLED STUDY; DEMYELINATING DISEASE; DEMYELINATION; DIPLOPIA; DISEASE SEVERITY; DIZZINESS; FEMALE; FIBRODYSPLASIA OSSIFICANS PROGRESSIVA; FIBROUS DYSPLASIA; GENE MUTATION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC MARKER; HEADACHE; HETEROTOPIC OSSIFICATION; HETEROZYGOSITY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; MYOCLONUS; NEUROPATHOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARESTHESIA; PRESCHOOL CHILD; PRIORITY JOURNAL; PROMOTER REGION; RETROSPECTIVE STUDY; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; WHITE MATTER LESION; WILD TYPE;

ADOLESCENT; ADULT; ANIMALS; CHILD, PRESCHOOL; DEMYELINATING DISEASES; FEMALE; HUMANS; MALE; MICE; MICE, TRANSGENIC; MYOSITIS OSSIFICANS; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 84872119229     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-012-6563-x     Document Type: Article

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