Trypanosomatid pin1-type peptidyl-prolyl isomerase is cytosolic and not essential for cell proliferation

Journal of Eukaryotic Microbiology

Volumn 60, Issue 1, 2013, Pages 101-105

  Erben, Esteban D ^a,c   Nardelli, Sheila C ^b,d   De Jesus, Teresa C L ^b,e   Schenkman, Sergio ^b   Tellez Iñon, Maria T ^a  

^a INSTITUTO DE INVESTIGACIONES EN INGENIERÍA GENÉTICA Y BIOLOGÍA MOLECULAR   (Argentina)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c GERMAN CANCER RESEARCH CENTER   (Germany)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

MORN domain; parvulin; peptidyl prolyl isomerase; Pin1; PPIase; Trypanosoma cruzi

Indexed keywords

NIMA INTERACTING PEPTIDYLPROLYL ISOMERASE; NIMA-INTERACTING PEPTIDYLPROLYL ISOMERASE; PEPTIDYLPROLYL ISOMERASE; PROTOZOAL PROTEIN; RECOMBINANT PROTEIN;

CELL ORGANELLE; ENZYME ACTIVITY; FLUORESCENCE; HOST-PARASITE INTERACTION; PEPTIDE; PROTOZOAN; RNA; YEAST;

ARTICLE; CELL CYCLE; CHEMISTRY; DNA SEQUENCE; ENZYMOLOGY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; RNA INTERFERENCE; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI; TWO HYBRID SYSTEM;

CELL CYCLE; GENE EXPRESSION REGULATION; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PEPTIDYLPROLYL ISOMERASE; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; RNA INTERFERENCE; SEQUENCE ANALYSIS, DNA; TRANSFECTION; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA CRUZI; TWO-HYBRID SYSTEM TECHNIQUES;

KINETOPLASTIDA; PROTOZOA; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI; TRYPANOSOMATIDAE;

EID: 84872082522     PISSN: 10665234     EISSN: 15507408     Source Type: Journal    
DOI: 10.1111/jeu.12009     Document Type: Article

References (23)

1. Crenshaw, D. G., Yang, J., Means, A. R., &, Kornbluth, S., 1998. The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1. EMBO J., 17: 1315-1327.
2. Devasahayam, G., Chaturvedi, V., &, Hanes, S. D., 2002. The Ess1 prolyl isomerase is required for growth and morphogenetic switching in Candida albicans. Genetics, 160: 37-48.
3. Erben, E. D., Daum, S., &, Tellez-Inon, M. T., 2007. The Trypanosoma cruzi PIN1 gene encodes a parvulin peptidyl-prolyl cis/trans isomerase able to replace the essential ESS1 in Saccharomyces cerevisiae. Mol. Biochem. Parasitol., 153: 186-193.
4. Erben, E. D., Valguarnera, E., Nardelli, S., Chung, J., Daum, S., Potenza, M., Schenkman, S., &, Tellez-Inon, M. T., 2010. Identification of an atypical peptidyl-prolyl cis/trans isomerase from trypanosomatids. Biochim. Biophys. Acta, 1803: 1028-1037.
5. Frank, R., 2002. The SPOT-synthesis technique. Synthetic peptide arrays on membrane supports-principles and applications. J. Immunol. Methods, 267: 13-26.
6. Goh, J. Y., Lai, C.-Y., Tan, L. C., Yang, D., He, C. Y., &, Liou, Y.-C., 2010. Functional characterization of two novel parvulins in Trypanosoma brucei. FEBS Lett., 584: 2901-2908.
7. Huang, H. K., Forsburg, S. L., John, U. P., O'Connell, M. J., &, Hunter, T., 2001. Isolation and characterization of the Pin1/Ess1p homologue in Schizosaccharomyces pombe. J. Cell Sci., 114: 3779-3788.
8. Kouri, E. D., Labrou, N. E., Garbis, S. D., Kalliampakou, K. I., Stedel, C., Dimou, M., Udvardi, M. K., Katinakis, P., &, Flemetakis, E., 2009. Molecular and biochemical characterization of the parvulin-type PPIases in Lotus japonicus. Plant Physiol., 150: 1160-1173.
9. Landrieu, I., De Veylder, L., Fruchart, J. S., Odaert, B., Casteels, P., Portetelle, D., Van Montagu, M., Inze, D., &, Lippens, G., 2000. The Arabidopsis thaliana PIN1At gene encodes a single-domain phosphorylation- dependent peptidyl prolyl cis/trans isomerase. J. Biol. Chem., 275: 10577-10581.
10. Lee, T. H., Chen, C. H., Suizu, F., Huang, P., Schiene-Fischer, C., Daum, S., Zhang, Y. J., Goate, A., Chen, R. H., Zhou, X. Z., &, Lu, K. P., 2011. Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function. Mol. Cell, 42: 147-159.
11. Liou, Y.-C., Zhou, X. Z., &, Lu, K. P., 2011. Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins. Trends Biochem. Sci., 36: 501-514.
12. Lu, K. P., Hanes, S. D., &, Hunter, T., 1996. A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature, 380: 544-547.
13. Lu, P. J., Zhou, X. Z., Liou, Y. C., Noel, J. P., &, Lu, K. P., 2002. Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function. J. Biol. Chem., 277: 2381-2384.
14. Lufei, C., &, Cao, X., 2009. Nuclear import of Pin1 is mediated by a novel sequence in the PPIase domain. FEBS Lett., 583: 271-276.
15. Metzner, M., Stoller, G., Rucknagel, K. P., Lu, K. P., Fischer, G., Luckner, M., &, Kullertz, G., 2001. Functional replacement of the essential ESS1 in yeast by the plant parvulin DlPar13. J. Biol. Chem., 276: 13524-13529.
16. Nett, I. R., Martin, D. M., Miranda-Saavedra, D., Lamont, D., Barber, J. D., Mehlert, A., &, Ferguson, M. A., 2009. The phosphoproteome of bloodstream form Trypanosoma brucei, causative agent of African sleeping sickness. Mol. Cell. Proteomics, 8: 1527-1538.
17. Ranganathan, R., Lu, K. P., Hunter, T., &, Noel, J. P., 1997. Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent. Cell, 89: 875-886.
18. Rippmann, J. F., Hobbie, S., Daiber, C., Guilliard, B., Bauer, M., Birk, J., Nar, H., Garin-Chesa, P., Rettig, W. J., &, Schnapp, A., 2000. Phosphorylation-dependent proline isomerization catalyzed by Pin1 is essential for tumor cell survival and entry into mitosis. Cell Growth Differ., 11: 409-416.
19. Shen, M., Stukenberg, P. T., Kirschner, M. W., &, Lu, K. P., 1998. The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins. Genes Dev., 12: 706-720.
20. Takeshima, H., Komazaki, S., Nishi, M., Iino, M., &, Kangawa, K., 2000. Junctophilins: a novel family of junctional membrane complex proteins. Mol. Cell, 6: 11-22.
21. Wang, Y., Liu, C., Yang, D., Yu, H., &, Liou, Y. C., 2010. Pin1At encoding a peptidyl-prolyl cis/trans isomerase regulates flowering time in Arabidopsis. Mol. Cell, 37: 112-122.
22. Winkler, K. E., Swenson, K. I., Kornbluth, S., &, Means, A. R., 2000. Requirement of the prolyl isomerase Pin1 for the replication checkpoint. Science, 287: 1644-1647.
23. Yao, J. L., Kops, O., Lu, P. J., &, Lu, K. P., 2001. Functional conservation of phosphorylation-specific prolyl isomerases in plants. J. Biol. Chem., 276: 13517-13523.