Early insulin glycemic control combined with tPA thrombolysis reduces acute brain tissue damages in a focal embolic stroke model of diabetic rats

Stroke

Volumn 44, Issue 1, 2013, Pages 255-259

  Fan, Xiang ^a   Ning, Mingming ^a   Lo, Eng H ^a   Wang, Xiaoying ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

focal embolic stroke; hyperglycemia; insulin glycemic control; rats; thrombolysis; tPA; Type I diabetes

Indexed keywords

INSULIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; BRAIN INFARCTION; BRAIN PERFUSION; CEREBROVASCULAR ACCIDENT; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBRINOLYTIC THERAPY; FOCAL EMBOLIC STROKE; GLYCEMIC CONTROL; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RAT; SWELLING;

ANIMALS; BLOOD GLUCOSE; BRAIN; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; GLYCEMIC INDEX; HUMANS; INSULIN; MALE; RATS; RATS, WISTAR; STROKE; THROMBOLYTIC THERAPY; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR;

EID: 84872072700     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.112.663476     Document Type: Article

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