메뉴 건너뛰기




Volumn 43, Issue 9, 2012, Pages 2343-2349

Intensive versus subcutaneous insulin in patients with hyperacute stroke: Results from the randomized INSULINFARCT trial

Author keywords

acute stroke; clinical trials; hyperglycemia; magnetic resonance imaging

Indexed keywords

GLUCOSE; INSULIN;

EID: 84865584625     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.112.657122     Document Type: Article
Times cited : (95)

References (30)
  • 1
    • 0037056360 scopus 로고    scopus 로고
    • Admission glucose level and clinical outcomes in the NINDS rtPA stroke trial
    • Bruno A, Levine SR, Frankel MR, Brott TG, Lin Y, Tilley BC, et al. Admission glucose level and clinical outcomes in the NINDS rtPA stroke trial. Neurology. 2002;59:669-674.
    • (2002) Neurology. , vol.59 , pp. 669-674
    • Bruno, A.1    Levine, S.R.2    Frankel, M.R.3    Brott, T.G.4    Lin, Y.5    Tilley, B.C.6
  • 2
    • 0034800666 scopus 로고    scopus 로고
    • Stress hyper-glycemia and prognosis of stroke in nondiabetic and diabetic patients: A systematic overview
    • Capes SE, Hunt D, Malmberg K, Pathak P, Gerstein HC. Stress hyper-glycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview. Stroke. 2001;32:2426-2432.
    • (2001) Stroke , vol.32 , pp. 2426-2432
    • Capes, S.E.1    Hunt, D.2    Malmberg, K.3    Pathak, P.4    Gerstein, H.C.5
  • 3
    • 46249131138 scopus 로고    scopus 로고
    • NXY-059 for the treatment of acute stroke: Pooled analysis of the SAINT i and II trials
    • Diener HC, Lees KR, Lyden P, Grotta J, Davalos A, Davis SM, et al. NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II trials. Stroke. 2008;39:1751-1758.
    • (2008) Stroke. , vol.39 , pp. 1751-1758
    • Diener, H.C.1    Lees, K.R.2    Lyden, P.3    Grotta, J.4    Davalos, A.5    Davis, S.M.6
  • 4
    • 77949491218 scopus 로고    scopus 로고
    • Hyperglycemia in acute ischemic stroke: Pathophysiology and clinical management
    • Kruyt ND, Biessels GJ, Devries JH, Roos YB. Hyperglycemia in acute ischemic stroke: pathophysiology and clinical management. Nat Rev Neurol. 2010;6:145-155.
    • (2010) Nat Rev Neurol , vol.6 , pp. 145-155
    • Kruyt, N.D.1    Biessels, G.J.2    Devries, J.H.3    Roos, Y.B.4
  • 5
    • 79952190509 scopus 로고    scopus 로고
    • Hyperglycaemia and infarct size in animal models of middle cerebral artery occlusion: Systematic review and meta-analysis
    • MacDougall NJ, Muir KW. Hyperglycaemia and infarct size in animal models of middle cerebral artery occlusion: systematic review and meta-analysis. J Cereb Blood Flow Metab. 2011;31:807-818.
    • (2011) J Cereb Blood Flow Metab. , vol.31 , pp. 807-818
    • MacDougall, N.J.1    Muir, K.W.2
  • 6
    • 7644228368 scopus 로고    scopus 로고
    • Impact of admission hyperglycemia on stroke outcome after thrombolysis: Risk stratification in relation to time to reperfusion
    • Alvarez-Sabin J, Molina CA, Ribo M, Arenillas JF, Montaner J, Huertas R, et al. Impact of admission hyperglycemia on stroke outcome after thrombolysis: risk stratification in relation to time to reperfusion. Stroke. 2004;35:2493-2498.
    • (2004) Stroke , vol.35 , pp. 2493-2498
    • Alvarez-Sabin, J.1    Molina, C.A.2    Ribo, M.3    Arenillas, J.F.4    Montaner, J.5    Huertas, R.6
  • 7
    • 0041917474 scopus 로고    scopus 로고
    • Persistent poststroke hyperglycemia is independently associated with infarct expansion and worse clinical outcome
    • Baird TA, Parsons MW, Phanh T, Butcher KS, Desmond PM, Tress BM, et al. Persistent poststroke hyperglycemia is independently associated with infarct expansion and worse clinical outcome. Stroke. 2003;34: 2208-2214.
    • (2003) Stroke , vol.34 , pp. 2208-2214
    • Baird, T.A.1    Parsons, M.W.2    Phanh, T.3    Butcher, K.S.4    Desmond, P.M.5    Tress, B.M.6
  • 8
    • 0036288571 scopus 로고    scopus 로고
    • Acute hyperglycemia adversely affects stroke outcome: A magnetic resonance imaging and spectroscopy study
    • Parsons MW, Barber PA, Desmond PM, Baird TA, Darby DG, Byrnes G, et al. Acute hyperglycemia adversely affects stroke outcome: a magnetic resonance imaging and spectroscopy study. Ann Neurol. 2002;52:20-28.
    • (2002) Ann Neurol , vol.52 , pp. 20-28
    • Parsons, M.W.1    Barber, P.A.2    Desmond, P.M.3    Baird, T.A.4    Darby, D.G.5    Byrnes, G.6
  • 11
    • 33644638104 scopus 로고    scopus 로고
    • Hyperglycemia, insulin, and acute ischemic stroke: A mechanistic justification for a trial of insulin infusion therapy
    • Garg R, Chaudhuri A, Munschauer F, Dandona P. Hyperglycemia, insulin, and acute ischemic stroke: a mechanistic justification for a trial of insulin infusion therapy. Stroke. 2006;37:267-273.
    • (2006) Stroke. , vol.37 , pp. 267-273
    • Garg, R.1    Chaudhuri, A.2    Munschauer, F.3    Dandona, P.4
  • 12
    • 64149131116 scopus 로고    scopus 로고
    • Hyperglycaemia in acute stroke\-to treat or not to treat
    • Quinn TJ, Lees KR. Hyperglycaemia in acute stroke\-to treat or not to treat. Cerebrovasc Dis. 2009;27(suppl 1):148-155.
    • (2009) Cerebrovasc Dis. , vol.27 , Issue.SUPPL. 1 , pp. 148-155
    • Quinn, T.J.1    Lees, K.R.2
  • 13
    • 39349094881 scopus 로고    scopus 로고
    • Treatment of Hyperglycemia in Ischemic Stroke (THIS): A randomized pilot trial
    • Bruno A, Kent TA, Coull BM, Shankar RR, Saha C, Becker KJ, et al. Treatment of Hyperglycemia in Ischemic Stroke (THIS): a randomized pilot trial. Stroke. 2008;39:384-389.
    • (2008) Stroke , vol.39 , pp. 384-389
    • Bruno, A.1    Kent, T.A.2    Coull, B.M.3    Shankar, R.R.4    Saha, C.5    Becker, K.J.6
  • 14
    • 34047255739 scopus 로고    scopus 로고
    • Glucose-potassium-insulin infusions in the management of post-stroke hyperglycaemia: The UK Glucose Insulin in Stroke Trial (GIST-UK)
    • Gray CS, Hildreth AJ, Sandercock PA, O'Connell JE, Johnston DE, Cartlidge NE, et al. Glucose-potassium-insulin infusions in the management of post-stroke hyperglycaemia: the UK Glucose Insulin in Stroke Trial (GIST-UK). Lancet Neurol. 2007;6:397-406.
    • (2007) Lancet Neurol , vol.6 , pp. 397-406
    • Gray, C.S.1    Hildreth, A.J.2    Sandercock, P.A.3    O'Connell, J.E.4    Johnston, D.E.5    Cartlidge, N.E.6
  • 15
    • 0028797405 scopus 로고
    • Insulin reduction of cerebral infarction due to transient focal ischemia
    • Hamilton MG, Tranmer BI, Auer RN. Insulin reduction of cerebral infarction due to transient focal ischemia. J Neurosurg. 1995;82:262-268.
    • (1995) J Neurosurg , vol.82 , pp. 262-268
    • Hamilton, M.G.1    Tranmer, B.I.2    Auer, R.N.3
  • 16
    • 73449126197 scopus 로고    scopus 로고
    • Glucose Regulation in Acute Stroke Patients (GRASP) trial: A randomized pilot trial
    • Johnston KC, Hall CE, Kissela BM, Bleck TP, Conaway MR. Glucose Regulation in Acute Stroke Patients (GRASP) trial: a randomized pilot trial. Stroke. 2009;40:3804-3809.
    • (2009) Stroke , vol.40 , pp. 3804-3809
    • Johnston, K.C.1    Hall, C.E.2    Kissela, B.M.3    Bleck, T.P.4    Conaway, M.R.5
  • 17
    • 57649135334 scopus 로고    scopus 로고
    • Pragmatic management of hyperglycaemia in acute ischaemic stroke: Safety and feasibility of intensive intravenous insulin treatment
    • Kreisel SH, Berschin UM, Hammes HP, Leweling H, Bertsch T, Hennerici MG, et al. Pragmatic management of hyperglycaemia in acute ischaemic stroke: safety and feasibility of intensive intravenous insulin treatment. Cerebrovasc Dis. 2009;27:167-175.
    • (2009) Cerebrovasc Dis , vol.27 , pp. 167-175
    • Kreisel, S.H.1    Berschin, U.M.2    Hammes, H.P.3    Leweling, H.4    Bertsch, T.5    Hennerici, M.G.6
  • 19
    • 79951880894 scopus 로고    scopus 로고
    • Intravenous insulin therapy in the maintenance of strict glycemic control in nondiabetic acute stroke patients with mild hyperglycemia
    • Staszewski J, Brodacki B, Kotowicz J, Stepien A. Intravenous insulin therapy in the maintenance of strict glycemic control in nondiabetic acute stroke patients with mild hyperglycemia. J Stroke Cerebrovasc Dis. 2010;20:150-154.
    • (2010) J Stroke Cerebrovasc Dis , vol.20 , pp. 150-154
    • Staszewski, J.1    Brodacki, B.2    Kotowicz, J.3    Stepien, A.4
  • 20
    • 33746326439 scopus 로고    scopus 로고
    • A randomised, controlled pilot study to investigate the potential benefit of intervention with insulin in hypergly-caemic acute ischaemic stroke patients
    • Walters MR, Weir CJ, Lees KR. A randomised, controlled pilot study to investigate the potential benefit of intervention with insulin in hypergly-caemic acute ischaemic stroke patients. Cerebrovasc Dis. 2006;22: 116-122.
    • (2006) Cerebrovasc Dis. , vol.22 , pp. 116-122
    • Walters, M.R.1    Weir, C.J.2    Lees, K.R.3
  • 21
    • 77951751809 scopus 로고    scopus 로고
    • Aggressive glucose control in acute stroke: Is the answer in the imaging?
    • Johnston KC, Parsons M. Aggressive glucose control in acute stroke: is the answer in the imaging? Ann Neurol. 2010;67:557-558.
    • (2010) Ann Neurol , vol.67 , pp. 557-558
    • Johnston, K.C.1    Parsons, M.2
  • 22
    • 84857647106 scopus 로고    scopus 로고
    • Glucose and acute stroke: Evidence for an interlude
    • Piironen K, Putaala J, Rosso C, Samson Y. Glucose and acute stroke: evidence for an interlude. Stroke. 2012;43:898-902.
    • (2012) Stroke. , vol.43 , pp. 898-902
    • Piironen, K.1    Putaala, J.2    Rosso, C.3    Samson, Y.4
  • 23
    • 33845415008 scopus 로고    scopus 로고
    • Intra-and interrater reliability of ischemic lesion volume measurements on diffusion-weighted, mean transit time and fluid-attenuated inversion recovery MRI
    • Luby M, Bykowski JL, Schellinger PD, Merino JG, Warach S. Intra-and interrater reliability of ischemic lesion volume measurements on diffusion-weighted, mean transit time and fluid-attenuated inversion recovery MRI. Stroke. 2006;37:2951-2956.
    • (2006) Stroke , vol.37 , pp. 2951-2956
    • Luby, M.1    Bykowski, J.L.2    Schellinger, P.D.3    Merino, J.G.4    Warach, S.5
  • 24
    • 58149359691 scopus 로고    scopus 로고
    • Prediction of infarct growth based on apparent diffusion coefficients: Penumbral assessment without intravenous contrast material
    • Rosso C, Hevia-Montiel N, Deltour S, Bardinet E, Dormont D, Crozier S, et al. Prediction of infarct growth based on apparent diffusion coefficients: penumbral assessment without intravenous contrast material. Radiology. 2009;250:184-192.
    • (2009) Radiology , vol.250 , pp. 184-192
    • Rosso, C.1    Hevia-Montiel, N.2    Deltour, S.3    Bardinet, E.4    Dormont, D.5    Crozier, S.6
  • 25
    • 0023889707 scopus 로고
    • Hyperglycemia enlarges infarct size in cerebrovascular occlusion in cats
    • de Courten-Myers G, Myers RE, Schoolfield L. Hyperglycemia enlarges infarct size in cerebrovascular occlusion in cats. Stroke. 1988;19: 623-630.
    • (1988) Stroke , vol.19 , pp. 623-630
    • De Courten-Myers, G.1    Myers, R.E.2    Schoolfield, L.3
  • 27
    • 7944227011 scopus 로고    scopus 로고
    • Optimal blood glucose levels while using insulin to minimize the size of infarction in focal cerebral ischemia
    • Zhu CZ, Auer RN. Optimal blood glucose levels while using insulin to minimize the size of infarction in focal cerebral ischemia. J Neurosurg. 2004;101:664-668.
    • (2004) J Neurosurg , vol.101 , pp. 664-668
    • Zhu, C.Z.1    Auer, R.N.2
  • 29
    • 84155185158 scopus 로고    scopus 로고
    • Assessing response to stroke thrombolysis: Validation of 24-hour multimodal magnetic resonance imaging
    • Campbell BC, Tu HT, Christensen S, Desmond PM, Levi CR, Bladin CF, et al. Assessing response to stroke thrombolysis: validation of 24-hour multimodal magnetic resonance imaging. Arch Neurol. 2012;69:46-50.
    • (2012) Arch Neurol , vol.69 , pp. 46-50
    • Campbell, B.C.1    Tu, H.T.2    Christensen, S.3    Desmond, P.M.4    Levi, C.R.5    Bladin, C.F.6
  • 30
    • 1942473685 scopus 로고    scopus 로고
    • IV insulin during acute cerebral infarction in diabetic patients
    • Bruno A, Saha C, Williams LS, Shankar R. IV insulin during acute cerebral infarction in diabetic patients. Neurology. 2004;62:1441-1442.
    • (2004) Neurology , vol.62 , pp. 1441-1442
    • Bruno, A.1    Saha, C.2    Williams, L.S.3    Shankar, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.