Electrographic status epilepticus is associated with mortality and worse short-term outcome in critically III children

Critical Care Medicine

Volumn 41, Issue 1, 2013, Pages 215-223

  Topjian, Alexis A ^a   Gutierrez Colina, Ana M ^a   Sanchez, Sarah M ^a   Berg, Robert A ^a   Friess, Stuart H ^a   Dlugos, Dennis J ^a,b   Abend, Nicholas S ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

electroencephalographic monitoring; nonconvulsive seizure; outcome; pediatric; seizure; status epilepticus

Indexed keywords

ARTICLE; BENIGN CHILDHOOD EPILEPSY; BRAIN DISEASE; CHILD; CRITICALLY ILL PATIENT; ELECTROENCEPHALOGRAPHY; EPILEPTIC STATE; FEMALE; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MORTALITY; NEUROMONITORING; OUTCOME ASSESSMENT; PERFORMANCE; PRESCHOOL CHILD; PRIORITY JOURNAL; RISK ASSESSMENT; SCHOOL CHILD; SEIZURE;

BRAIN DISEASES; CHILD; CHILD, PRESCHOOL; CRITICAL ILLNESS; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; INFANT; INTENSIVE CARE UNITS, PEDIATRIC; LOGISTIC MODELS; MALE; MULTIVARIATE ANALYSIS; PROGNOSIS; PROSPECTIVE STUDIES; SEIZURES; STATUS EPILEPTICUS; UNITED STATES;

EID: 84872066421     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3182668035     Document Type: Article

References (41)

1. Abend NS, Gutierrez-Colina AM, Topjian AA, et al: Nonconvulsive seizures are common in critically ill children. Neurology 2011; 76:1071-1077
2. Hyllienmark L, Amark P: Continuous EEG monitoring in a paediatric intensive care unit. Eur J Paediatr Neurol 2007; 11:70-75
3. Hosain SA, Solomon GE, Kobylarz EJ: Electroencephalographic patterns in unresponsive pediatric patients. Pediatr Neurol 2005; 32:162-165
4. Jette N, Claassen J, Emerson RG, et al: Frequency and predictors of nonconvulsive seizures during continuous electroencephalographic monitoring in critically ill children. Arch Neurol 2006; 63:1750-1755
5. Abend NS, Topjian A, Ichord R, et al: Electroencephalographic monitoring during hypothermia after pediatric cardiac arrest. Neurology 2009; 72:1931-1940
6. Abend NS, Dlugos DJ: Nonconvulsive status epilepticus in a pediatric intensive care unit. Pediatr Neurol 2007; 37:165-170
7. Saengpattrachai M, Sharma R, Hunjan A, et al: Nonconvulsive seizures in the pediatric intensive care unit: Etiology, EEG, and brain imaging findings. Epilepsia 2006; 47:1510-1518
8. Alehan FK, Morton LD, Pellock JM: Utility of electroencephalography in the pediatric emergency department. J Child Neurol 2001; 16:484-487
9. Tay SK, Hirsch LJ, Leary L, et al: Nonconvulsive status epilepticus in children: Clinical and EEG characteristics. Epilepsia 2006; 47:1504-1509
10. Shahwan A, Bailey C, Shekerdemian L, et al: The prevalence of seizures in comatose children in the pediatric intensive care unit: A prospective video-EEG study. Epilepsia 2010; 51:1198-1204
11. Williams K, Jarrar R, Buchhalter J: Continuous video-EEG monitoring in pediatric intensive care units. Epilepsia 2011; 52:1130-1136
12. McCoy B, Sharma R, Ochi A, et al: Predictors of nonconvulsive seizures among critically ill children. Epilepsia 2011; 52:1973-1978
13. Greiner HM, Holland K, Leach JL, et al: Nonconvulsive status epilepticus: The encephalopathic pediatric patient. Pediatrics 2012; 129:e748-e755
14. Vespa PM, Miller C, McArthur D, et al: Nonconvulsive electrographic seizures after traumatic brain injury result in a delayed, prolonged increasein intracranial pressure and metabolic crisis. Crit Care Med 2007; 35:2830-2836
15. Vespa PM, McArthur DL, Xu Y, et al: Nonconvulsive seizures after traumatic brain injury are associated with hippocampal atrophy. Neurology 2010; 75:792-798
16. Young GB, Jordan KG, Doig GS: An assessment of nonconvulsive seizures in the intensive care unit using continuous EEG monitoring: An investigation of variables associated with mortality. Neurology 1996; 47:83-89
17. Oddo M, Carrera E, Claassen J, et al: Continuous electroencephalography in the medical intensive care unit. Crit Care Med 2009; 37:2051-2056
18. Carrera E, Claassen J, Oddo M, et al: Continuous electroencephalographic monitoring in critically ill patients with central nervous system infections. Arch Neurol 2008; 65:1612-1618
19. McBride MC, Laroia N, Guillet R: Electrographic seizures in neonates correlate with poor neurodevelopmental outcome. Neurology 2000; 55:506-513
20. Pisani F, Cerminara C, Fusco C, et al: Neonatal status epilepticus vs recurrent neonatal seizures: Clinical findings and outcome. Neurology 2007; 69:2177-2185
21. Pollack MM, Patel KM, Ruttimann UE: PRISM III: An updated Pediatric Risk of Mortality score. Crit Care Med 1996; 24:743-752
22. Nishisaki A, Sullivan J 3rd, Steger B, et al: Retrospective analysis of the prognostic value of electroencephalography patterns obtained in pedi atric in-hospital cardiac arrest survivors during three years. Pediatr Crit Care Med 2007; 8:10-17
23. Kessler SK, Topjian AA, Gutierrez-Colina AM, et al: Short-term outcome prediction by electroencephalographic features in children treated with therapeutic hypothermia after cardiac arrest. Neurocrit Care 2011; 14:37-43
24. Fiser DH, Long N, Roberson PK, et al: Relationship of pediatric overall performance category and pediatric cerebral performance category scores at pediatric intensive care unit discharge with outcome measures collected at hospital discharge and 1-and 6-month follow-up assessments. Crit Care Med 2000; 28:2616-2620
25. Claassen J, Mayer SA, Kowalski RG, et al: Detection of electrographic seizures with continuous EEG monitoring in critically ill patients. Neurology 2004; 62:1743-1748
26. Vespa PM, O'Phelan K, Shah M, et al: Acute seizures after intracerebral hemorrhage: A factor in progressive midline shift and outcome. Neurology 2003; 60:1441-1446
27. Clancy RR, Legido A, Lewis D: Occult neonatal seizures. Epilepsia 1988; 29:256-261
28. Wusthoff CJ, Dlugos DJ, Gutierrez-Colina A, et al: Electrographic seizures during therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy. J Child Neurol 2011; 26:724-728
29. Nash KB, Bonifacio SL, Glass HC, et al: Video-EEG monitoring in newborns with hypoxic-ischemic encephalopathy treated with hypothermia. Neurology 2011; 76:556-562
30. Scher MS, Alvin J, Gaus L, et al: Uncoupling of EEG-clinical neonatal seizures after antiepileptic drug use. Pediatr Neurol 2003; 28:277-280
31. Hauf M, Slotboom J, Nirkko A, et al: Cortical regional hyperperfusion in nonconvulsive status epilepticus measured by dynamic brain perfusion CT. AJNR Am J Neuroradiol 2009; 30:693-698
32. Pampiglione G, Harden A: Resuscitation after cardiocirculatory arrest. Prognostic evaluation of early electroencephalographic findings. Lancet 1968; 1:1261-1265
33. Tasker RC, Boyd S, Harden A, et al: Monitoring in non-traumatic coma. Part II: Electroencephalography. Arch Dis Child 1988; 63:895-899
34. Cheliout-Heraut F, Sale-Franque F, Hubert P, et al: Cerebral anoxia in near-drowning of children. The prognostic value of EEG. Neurophysiol Clin 1991; 21: 121-132
35. Ramachandrannair R, Sharma R, Weiss SK, et al: Reactive EEG patterns in pediatric coma. Pediatr Neurol 2005; 33:345-349
36. Mandel R, Martinot A, Delepoulle F, et al: Prediction of outcome after hypoxic-ischemic encephalopathy: A prospective clinical and electrophysiologic study. J Pediatr 2002; 141:45-50
37. Pampiglione G, Chaloner J, Harden A, et al: Transitory ischemia/anoxia in young children and the prediction of quality of survival. Ann N Y Acad Sci 1978; 315:281-292
38. Evans BM, Bartlett JR: Prediction of outcome in severe head injury based on recognition of sleep related activity in the polygraphic electroencephalogram. J Neurol Neurosurg Psychiatr 1995; 59:17-25
39. Abend NS, Dlugos DJ, Hahn CD, et al: Use of EEG monitoring and management of non-convulsive seizures in critically ill patients: A survey of neurologists. Neurocrit Care 2010; 12:382-389
40. Chong DJ, Hirsch LJ: Which EEG patterns warrant treatment in the critically ill? Reviewing the evidence for treatment of periodic epileptiform discharges and related patterns. J Clin Neurophysiol 2005; 22:79-91
41. Jirsch J, Hirsch LJ: Nonconvulsive seizures: Developing a rational approach to the diagnosis and management in the critically ill population. Clin Neurophysiol 2007; 118:1660-1670