메뉴 건너뛰기




Volumn 21, Issue 1, 2013, Pages 97-106

Characterization of Calu-3 cell monolayers as a model of bronchial epithelial transport: Organic cation interaction studies

Author keywords

Carnitine organic cation transporter (OCTN1, OCTN2); Organic cation transporters (OCT1 3); Pulmonary epithelium

Indexed keywords

CARNITINE; CATION; CORTICOSTERONE; FLUORESCENT DYE; VERAPAMIL;

EID: 84872042131     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2012.731068     Document Type: Article
Times cited : (26)

References (32)
  • 1
    • 79953290962 scopus 로고    scopus 로고
    • Caco-2 cells as a model for intestinal absorption
    • Angelis ID, Turco L. (2011). Caco-2 cells as a model for intestinal absorption. Curr Protoc Toxicol, 47, 20.6.1-20.6.15.
    • (2011) Curr Protoc Toxicol , vol.47 , pp. 2061-20615
    • Angelis, I.D.1    Turco, L.2
  • 2
    • 77951277135 scopus 로고    scopus 로고
    • Drug transporters in the lung-do they play a role in the biopharmaceutics of inhaled drugs?
    • Bosquillon C. (2010). Drug transporters in the lung-do they play a role in the biopharmaceutics of inhaled drugs? J Pharm Sci, 99, 2240-2255.
    • (2010) J Pharm Sci , vol.99 , pp. 2240-2255
    • Bosquillon, C.1
  • 4
    • 75349108981 scopus 로고    scopus 로고
    • Preclinical models for pulmonary drug delivery
    • Fernandes CA, Vanbever R. (2009). Preclinical models for pulmonary drug delivery. Expert Opin Drug Deliv, 6, 1231-1245.
    • (2009) Expert Opin Drug Deliv , vol.6 , pp. 1231-1245
    • Fernandes, C.A.1    Vanbever, R.2
  • 6
    • 0037458930 scopus 로고    scopus 로고
    • Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3
    • Florea BI, Cassara ML, Junginger HE, Borchard G. (2003). Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3. J Control Release, 87, 131-138.
    • (2003) J Control Release , vol.87 , pp. 131-138
    • Florea, B.I.1    Cassara, M.L.2    Junginger, H.E.3    Borchard, G.4
  • 9
    • 59649127836 scopus 로고    scopus 로고
    • The carnitine transporter SLC22A5 is not a general drug transporter, but it efciently translocates mildronate
    • Grigat S, Fork C, Bach M, Golz S, Geerts A, Schömig E, Gründemann D. (2009). The carnitine transporter SLC22A5 is not a general drug transporter, but it efciently translocates mildronate. Drug Metab Dispos, 37, 330-337.
    • (2009) Drug Metab Dispos , vol.37 , pp. 330-337
    • Grigat, S.1    Fork, C.2    Bach, M.3    Golz, S.4    Geerts, A.5    Schömig, E.6    Gründemann, D.7
  • 10
    • 0035032962 scopus 로고    scopus 로고
    • P-glycoprotein efux pump expression and activity in Calu-3 cells
    • Hamilton KO, Backstrom G, Yazdanian MA, Audus KL. (2001). P-glycoprotein efux pump expression and activity in Calu-3 cells. J Pharm Sci, 90, 647-658.
    • (2001) J Pharm Sci , vol.90 , pp. 647-658
    • Hamilton, K.O.1    Backstrom, G.2    Yazdanian, M.A.3    Audus, K.L.4
  • 11
    • 79952196976 scopus 로고    scopus 로고
    • 3D cell culture: A review of current approaches and techniques
    • Haycock JW. (2011). 3D cell culture: a review of current approaches and techniques. Methods Mol Biol, 695, 1-15.
    • (2011) Methods Mol Biol , vol.695 , pp. 1-15
    • Haycock, J.W.1
  • 14
    • 24144434422 scopus 로고    scopus 로고
    • Molecular and functional characterization of an Na+-independent choline transporter in rat astrocytes
    • Inazu M, Takeda H, Matsumiya T. (2005). Molecular and functional characterization of an Na+-independent choline transporter in rat astrocytes. J Neurochem, 94, 1427-1437.
    • (2005) J Neurochem , vol.94 , pp. 1427-1437
    • Inazu, M.1    Takeda, H.2    Matsumiya, T.3
  • 15
    • 34249943356 scopus 로고    scopus 로고
    • Polyspecifc organic cation transporters: Structure, function, physiological roles, and biopharmaceutical implications
    • Koepsell H, Lips K, Volk C. (2007). Polyspecifc organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications. Pharm Res, 24, 1227-1251.
    • (2007) Pharm Res , vol.24 , pp. 1227-1251
    • Koepsell, H.1    Lips, K.2    Volk, C.3
  • 16
    • 48749124897 scopus 로고    scopus 로고
    • The epithelial cholinergic system of the airways
    • Kummer W, Lips KS, Pfeil U. (2008). The epithelial cholinergic system of the airways. Histochem Cell Biol, 130, 219-234.
    • (2008) Histochem Cell Biol , vol.130 , pp. 219-234
    • Kummer, W.1    Lips, K.S.2    Pfeil, U.3
  • 18
    • 0035166153 scopus 로고    scopus 로고
    • Apical uptake of organic cations by human intestinal Caco-2 cells: Putative involvement of ASF transporters
    • Martel F, Gründemann D, Calhau C, Schömig E. (2001). Apical uptake of organic cations by human intestinal Caco-2 cells: putative involvement of ASF transporters. Naunyn Schmiedebergs Arch Pharmacol, 363, 40-49.
    • (2001) Naunyn Schmiedebergs Arch Pharmacol , vol.363 , pp. 40-49
    • Martel, F.1    Gründemann, D.2    Calhau, C.3    Schömig, E.4
  • 19
    • 84857792529 scopus 로고    scopus 로고
    • Evaluation of air-interfaced Calu-3 cell layers for investigation of inhaled drug interactions with organic cation transporters in vitro
    • Mukherjee M, Pritchard DI, Bosquillon C. (2012). Evaluation of air-interfaced Calu-3 cell layers for investigation of inhaled drug interactions with organic cation transporters in vitro. Int J Pharm, 426, 7-14.
    • (2012) Int J Pharm , vol.426 , pp. 7-14
    • Mukherjee, M.1    Pritchard, D.I.2    Bosquillon, C.3
  • 20
    • 76249120508 scopus 로고    scopus 로고
    • Transport of ipratropium, an anti-chronic obstructive pulmonary disease drug, is mediated by organic cation/carnitine transporters in human bronchial epithelial cells: Implications for carrier-mediated pulmonary absorption
    • Nakamura T, Nakanishi T, Haruta T, Shirasaka Y, Keogh JP, Tamai I. (2010). Transport of ipratropium, an anti-chronic obstructive pulmonary disease drug, is mediated by organic cation/carnitine transporters in human bronchial epithelial cells: implications for carrier-mediated pulmonary absorption. Mol Pharm, 7, 187-195.
    • (2010) Mol Pharm , vol.7 , pp. 187-195
    • Nakamura, T.1    Nakanishi, T.2    Haruta, T.3    Shirasaka, Y.4    Keogh, J.P.5    Tamai, I.6
  • 21
    • 0032696186 scopus 로고    scopus 로고
    • Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): Its pharmacological and toxicological relevance
    • Ohashi R, Tamai I, Yabuuchi H, Nezu JI, Oku A, Sai Y, Shimane M, Tsuji A. (1999). Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. J Pharmacol Exp Ter, 291, 778-784.
    • (1999) J Pharmacol Exp ter , vol.291 , pp. 778-784
    • Ohashi, R.1    Tamai, I.2    Yabuuchi, H.3    Nezu, J.I.4    Oku, A.5    Sai, Y.6    Shimane, M.7    Tsuji, A.8
  • 22
    • 70649101231 scopus 로고    scopus 로고
    • Identifcation and functional characterization of breast cancer resistance protein in human bronchial epithelial cells (Calu-3)
    • Paturi DK, Kwatra D, Ananthula HK, Pal D, Mitra AK. (2010). Identifcation and functional characterization of breast cancer resistance protein in human bronchial epithelial cells (Calu-3). Int J Pharm, 384, 32-38.
    • (2010) Int J Pharm , vol.384 , pp. 32-38
    • Paturi, D.K.1    Kwatra, D.2    Ananthula, H.K.3    Pal, D.4    Mitra, A.K.5
  • 24
    • 84861824412 scopus 로고    scopus 로고
    • Organic cation transporters in the blood-air barrier: Expression and implications for pulmonary drug delivery
    • Salomon JJ, Ehrhardt C. (2012). Organic cation transporters in the blood-air barrier: expression and implications for pulmonary drug delivery. Ter Deliv, 3, 735-747.
    • (2012) Ter Deliv , vol.3 , pp. 735-747
    • Salomon, J.J.1    Ehrhardt, C.2
  • 25
    • 84861624577 scopus 로고    scopus 로고
    • Transport of the fuorescent organic cation 4-(4-(dimethylamino) styryl)-N-methylpyridinium iodide (ASP+) in human respiratory epithelial cells
    • Salomon JJ, Endter S, Tachon G, Falson F, Buckley ST, Ehrhardt C. (2012). Transport of the fuorescent organic cation 4-(4-(dimethylamino) styryl)-N-methylpyridinium iodide (ASP+) in human respiratory epithelial cells. Eur J Pharm Biopharm, 81, 351-359.
    • (2012) Eur J Pharm Biopharm , vol.81 , pp. 351-359
    • Salomon, J.J.1    Endter, S.2    Tachon, G.3    Falson, F.4    Buckley, S.T.5    Ehrhardt, C.6
  • 26
    • 84872025322 scopus 로고    scopus 로고
    • Renal transport of organic ions and uric acid
    • Schrier RW, ed Philadelphia: Lippincott Williams and Wilkins (LWW)
    • Schild L, Roch-Ramel F, Diezi J. (2007). Renal transport of organic ions and uric acid. In: Schrier RW, ed. Diseases of the Kidney and Urinary Tract. Philadelphia: Lippincott Williams and Wilkins (LWW), 218-233.
    • (2007) Diseases of the Kidney and Urinary Tract , pp. 218-233
    • Schild, L.1    Roch-Ramel, F.2    Diezi, J.3
  • 27
    • 44349119818 scopus 로고    scopus 로고
    • In vitro cell culture models for the assessment of pulmonary drug disposition
    • Sporty JL, Horálková L, Ehrhardt C. (2008). In vitro cell culture models for the assessment of pulmonary drug disposition. Expert Opin Drug Metab Toxicol, 4, 333-345.
    • (2008) Expert Opin Drug Metab Toxicol , vol.4 , pp. 333-345
    • Sporty, J.L.1    Horálková, L.2    Ehrhardt, C.3
  • 28
    • 21344471653 scopus 로고    scopus 로고
    • Cell culture models of the respiratory tract relevant to pulmonary drug delivery
    • Steimer A, Haltner E, Lehr CM. (2005). Cell culture models of the respiratory tract relevant to pulmonary drug delivery. J Aerosol Med, 18, 137-182.
    • (2005) J Aerosol Med , vol.18 , pp. 137-182
    • Steimer, A.1    Haltner, E.2    Lehr, C.M.3
  • 29
    • 2942585051 scopus 로고    scopus 로고
    • In vitro testing of drug absorption for drug 'developability' assessment: Forming an interface between in vitro preclinical data and clinical outcome
    • Sun D, Yu LX, Hussain MA, Wall DA, Smith RL, Amidon GL. (2004). In vitro testing of drug absorption for drug 'developability' assessment: forming an interface between in vitro preclinical data and clinical outcome. Curr Opin Drug Discov Devel, 7, 75-85.
    • (2004) Curr Opin Drug Discov Devel , vol.7 , pp. 75-85
    • Sun, D.1    Yu, L.X.2    Hussain, M.A.3    Wall, D.A.4    Smith, R.L.5    Amidon, G.L.6
  • 30
    • 84855870732 scopus 로고    scopus 로고
    • Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: A comparison
    • Vllasaliu D, Fowler R, Garnett M, Eaton M, Stolnik S. (2011). Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: a comparison. Biochem Biophys Res Commun, 415, 579-585.
    • (2011) Biochem Biophys Res Commun , vol.415 , pp. 579-585
    • Vllasaliu, D.1    Fowler, R.2    Garnett, M.3    Eaton, M.4    Stolnik, S.5
  • 31
    • 0032935034 scopus 로고    scopus 로고
    • Novel membrane transporter OCTN1 mediates multispecifc, bidirectional, and pH-dependent transport of organic cations
    • Yabuuchi H, Tamai I, Nezu J, Sakamoto K, Oku A, Shimane M, Sai Y, Tsuji A. (1999). Novel membrane transporter OCTN1 mediates multispecifc, bidirectional, and pH-dependent transport of organic cations. J Pharmacol Exp Ter, 289, 768-773.
    • (1999) J Pharmacol Exp ter , vol.289 , pp. 768-773
    • Yabuuchi, H.1    Tamai, I.2    Nezu, J.3    Sakamoto, K.4    Oku, A.5    Shimane, M.6    Sai, Y.7    Tsuji, A.8
  • 32
    • 79951717126 scopus 로고    scopus 로고
    • Cultured human airway epithelial cells (calu-3): A model of human respiratory function, structure, and infammatory responses
    • Zhu Y, Chidekel A, Shafer TH. (2010). Cultured human airway epithelial cells (calu-3): a model of human respiratory function, structure, and infammatory responses. Crit Care Res Pract, 2010.
    • (2010) Crit Care Res Pract , pp. 2010
    • Zhu, Y.1    Chidekel, A.2    Shafer, T.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.