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Volumn 155, Issue 1, 2013, Pages 141-149

The protective effect of 2-mercaptoethane sulfonate (MESNA) against traumatic brain injury in rats

Author keywords

2 mercaptoethane sulfonate; Antiapoptosis; Antioxidation; Methylprednisolone; Neuroprotection; Traumatic brain injury

Indexed keywords

CASPASE 3; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; MESNA; METHYLPREDNISOLONE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SUPEROXIDE DISMUTASE; XANTHINE OXIDASE;

EID: 84872037418     PISSN: 00016268     EISSN: 09420940     Source Type: Journal    
DOI: 10.1007/s00701-012-1501-3     Document Type: Article
Times cited : (18)

References (42)
  • 1
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthases: Structure, function and inhibition
    • 11463332 10.1042/0264-6021:3570593 1:CAS:528:DC%2BD3MXmtFent70%3D
    • Alderton WK, Cooper CE, Knowles RG (2001) Nitric oxide synthases: structure, function and inhibition. Biochem J 357:593-615
    • (2001) Biochem J , vol.357 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 2
    • 79955574686 scopus 로고    scopus 로고
    • 2-Mercaptoethane sulfonate prevents doxorubicin-induced plasma protein oxidation and TNF-α release: Implications for the reactive oxygen species-mediated mechanisms of chemobrain
    • 21421044 10.1016/j.freeradbiomed.2011.03.009 1:CAS:528: DC%2BC3MXlvVWhtbo%3D
    • Aluise CD, Miriyala S, Noel T, Sultana R, Jungsuwadee P, Taylor TJ, Cai J, Pierce WM, Vore M, Moscow JA, St Clair DK, Butterfield DA (2011) 2-Mercaptoethane sulfonate prevents doxorubicin-induced plasma protein oxidation and TNF-α release: implications for the reactive oxygen species-mediated mechanisms of chemobrain. Free Radic Biol Med 50:1630-1638
    • (2011) Free Radic Biol Med , vol.50 , pp. 1630-1638
    • Aluise, C.D.1    Miriyala, S.2    Noel, T.3    Sultana, R.4    Jungsuwadee, P.5    Taylor, T.J.6    Cai, J.7    Pierce, W.M.8    Vore, M.9    Moscow, J.A.10    St Clair, D.K.11    Butterfield, D.A.12
  • 3
    • 33846660955 scopus 로고    scopus 로고
    • Neuroprotection by resveratrol against traumatic brain injury in rats
    • 16924419 10.1007/s11010-006-9253-0 1:CAS:528:DC%2BD2sXnvVSjtQ%3D%3D
    • Ates O, Cayli S, Altinoz E, Gurses I, Yucel N, Sener M, Kocak A, Yologlu S (2007) Neuroprotection by resveratrol against traumatic brain injury in rats. Mol Cell Biochem 294:137-144
    • (2007) Mol Cell Biochem , vol.294 , pp. 137-144
    • Ates, O.1    Cayli, S.2    Altinoz, E.3    Gurses, I.4    Yucel, N.5    Sener, M.6    Kocak, A.7    Yologlu, S.8
  • 4
    • 0030969530 scopus 로고    scopus 로고
    • Oxidative stress following traumatic brain injury in rats
    • 9167783 10.1016/S0090-3019(96)00461-2 1:STN:280:DyaK2szhtVKitA%3D%3D
    • Awasthi D, Church DF, Torbati D, Carey ME, Pryor WA (1997) Oxidative stress following traumatic brain injury in rats. Surg Neurol 47:575-581
    • (1997) Surg Neurol , vol.47 , pp. 575-581
    • Awasthi, D.1    Church, D.F.2    Torbati, D.3    Carey, M.E.4    Pryor, W.A.5
  • 5
    • 0019946950 scopus 로고
    • Protective role of thiols in cyclophosphamide-induced urotoxicity and depression of hepatic drug metabolism
    • 6809312 1:CAS:528:DyaL38Xltlyhur8%3D
    • Berrigan MJ, Marinello AJ, Pavelic Z, Williams CJ, Struck RF, Gurtoo HL (1982) Protective role of thiols in cyclophosphamide-induced urotoxicity and depression of hepatic drug metabolism. Cancer Res 42:3688-3695
    • (1982) Cancer Res , vol.42 , pp. 3688-3695
    • Berrigan, M.J.1    Marinello, A.J.2    Pavelic, Z.3    Williams, C.J.4    Struck, R.F.5    Gurtoo, H.L.6
  • 6
    • 1042301370 scopus 로고    scopus 로고
    • Pathophysiology of cerebral ischemia and brain trauma: Similarities and differences
    • 14747740 10.1097/01.WCB.0000111614.19196.04
    • Bramlett HM, Dietrich WD (2004) Pathophysiology of cerebral ischemia and brain trauma: similarities and differences. J Cereb Blood Flow Metab 24:133-150
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 133-150
    • Bramlett, H.M.1    Dietrich, W.D.2
  • 7
    • 0034608570 scopus 로고    scopus 로고
    • Lipid peroxidation inhibition in spinal cord injury: Cyclosporin-A vs methylprednisolone
    • 10852240 10.1097/00001756-200006050-00033 1:CAS:528:DC%2BD3cXktlGitb0%3D
    • Diaz-Ruiz A, Rios C, Duarte I, Correa D, Guizar-Sahagun G, Grijalva I, Madrazo I, Ibarra A (2000) Lipid peroxidation inhibition in spinal cord injury: cyclosporin-A vs methylprednisolone. NeuroReport 11:1765-1767
    • (2000) NeuroReport , vol.11 , pp. 1765-1767
    • Diaz-Ruiz, A.1    Rios, C.2    Duarte, I.3    Correa, D.4    Guizar-Sahagun, G.5    Grijalva, I.6    Madrazo, I.7    Ibarra, A.8
  • 8
    • 77349093756 scopus 로고    scopus 로고
    • Neuroprotective effect of mesna (2-mercaptoethane sulfonate) against spinal cord ischemia/reperfusion injury in rabbits
    • 20117935 10.1016/j.jocn.2009.07.108 1:CAS:528:DC%2BC3cXivFKgsbg%3D
    • Dolgun H, Sekerci Z, Turkoglu E, Kertmen H, Yilmaz ER, Anlar M, Erguder IB, Tuna H (2010) Neuroprotective effect of mesna (2-mercaptoethane sulfonate) against spinal cord ischemia/reperfusion injury in rabbits. J Clin Neurosci 17:486-489
    • (2010) J Clin Neurosci , vol.17 , pp. 486-489
    • Dolgun, H.1    Sekerci, Z.2    Turkoglu, E.3    Kertmen, H.4    Yilmaz, E.R.5    Anlar, M.6    Erguder, I.B.7    Tuna, H.8
  • 10
    • 0035403177 scopus 로고    scopus 로고
    • Effects of deferoxamine on tissue superoxide dismutase and glutathione peroxidase levels in experimental head trauma
    • 11468462 10.1097/00005373-200107000-00004
    • Erkan Ustün M, Md AD, Oztin Oǧün C, Sümer F, Gürbilek M (2001) Effects of deferoxamine on tissue superoxide dismutase and glutathione peroxidase levels in experimental head trauma. J Trauma 51:22-25
    • (2001) J Trauma , vol.51 , pp. 22-25
    • Erkan Ustün, M.1    Md, A.D.2    Oztin Oǧün, C.3    Sümer, F.4    Gürbilek, M.5
  • 11
    • 0027265381 scopus 로고
    • Free radicals in brain metabolism and pathology
    • 8221024 1:CAS:528:DyaK2cXltFaguw%3D%3D
    • Evans PH (1993) Free radicals in brain metabolism and pathology. Br Med Bull 49:577-587
    • (1993) Br Med Bull , vol.49 , pp. 577-587
    • Evans, P.H.1
  • 12
    • 0029009063 scopus 로고
    • Scavenging of reactive oxygen species by letosteine, a molecule with two blocked-SH groups. Comparison with free-SH drugs
    • 7550053 10.1007/BF01875435 1:CAS:528:DyaK2MXnt12gs7c%3D
    • Gressier B, Lebegue N, Brunet C, Luyckx M, Dine T, Cazin M, Cazin JC (1995) Scavenging of reactive oxygen species by letosteine, a molecule with two blocked-SH groups. Comparison with free-SH drugs. Pharm World Sci 17:76-80
    • (1995) Pharm World Sci , vol.17 , pp. 76-80
    • Gressier, B.1    Lebegue, N.2    Brunet, C.3    Luyckx, M.4    Dine, T.5    Cazin, M.6    Cazin, J.C.7
  • 13
    • 0028102181 scopus 로고
    • Pro-oxidant properties of methotrexate: Evaluation and prevention by an anti-oxidant drug
    • 7972312 1:CAS:528:DyaK2cXmslWmtrY%3D
    • Gressier B, Lebegue S, Brunet C, Luyckx M, Dine T, Cazin M, Cazin JC (1994) Pro-oxidant properties of methotrexate: evaluation and prevention by an anti-oxidant drug. Pharmazie 49:679-681
    • (1994) Pharmazie , vol.49 , pp. 679-681
    • Gressier, B.1    Lebegue, S.2    Brunet, C.3    Luyckx, M.4    Dine, T.5    Cazin, M.6    Cazin, J.C.7
  • 14
    • 0024589421 scopus 로고
    • Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation
    • 2663663 10.1016/0891-5849(89)90057-9 1:STN:280:DyaL1Mzgs1ymtQ%3D%3D
    • Hall ED, Braughler JM (1989) Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation. Free Radic Biol Med 6:303-313
    • (1989) Free Radic Biol Med , vol.6 , pp. 303-313
    • Hall, E.D.1    Braughler, J.M.2
  • 15
    • 0029347181 scopus 로고
    • Flavoprotein structure and mechanism. 4. Xanthine oxidase and xanthine dehydrogenase
    • 7649415 1:CAS:528:DyaK2MXns1Smsbk%3D
    • Hille R, Nishino T (1995) Flavoprotein structure and mechanism. 4. Xanthine oxidase and xanthine dehydrogenase. FASEB J 9:995-1003
    • (1995) FASEB J , vol.9 , pp. 995-1003
    • Hille, R.1    Nishino, T.2
  • 16
    • 0025285843 scopus 로고
    • The molecular basis of brain injury and brain edema: The role of oxygen free radicals
    • 2198480 10.1227/00006123-199007000-00001 1:STN:280:DyaK3czjt1Squw%3D%3D
    • Ikeda Y, Long DM (1990) The molecular basis of brain injury and brain edema: the role of oxygen free radicals. Neurosurgery 27:1-11
    • (1990) Neurosurgery , vol.27 , pp. 1-11
    • Ikeda, Y.1    Long, D.M.2
  • 19
    • 0022881755 scopus 로고
    • Oxygen radicals in brain injury
    • 3107844 1:STN:280:DyaL2s3hs1Sitw%3D%3D
    • Kontos HA, Povlishock JT (1986) Oxygen radicals in brain injury. Cent Nerv Syst Trauma 3:257-263
    • (1986) Cent Nerv Syst Trauma , vol.3 , pp. 257-263
    • Kontos, H.A.1    Povlishock, J.T.2
  • 20
    • 0141994815 scopus 로고    scopus 로고
    • Monoubiquitination and cellular distribution of XIAP in neurons after traumatic brain injury
    • 14526223 10.1097/01.WCB.0000086938.68719.E0 1:CAS:528: DC%2BD3sXnslaqsLY%3D
    • Lotocki G, Alonso OF, Frydel B, Dietrich WD, Keane RW (2003) Monoubiquitination and cellular distribution of XIAP in neurons after traumatic brain injury. J Cereb Blood Flow Metab 23:1129-1136
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 1129-1136
    • Lotocki, G.1    Alonso, O.F.2    Frydel, B.3    Dietrich, W.D.4    Keane, R.W.5
  • 21
    • 0029954547 scopus 로고    scopus 로고
    • Ischemia- reperfusion injury in the spinal cord of rabbits strongly enhances lipid peroxidation and modifies phospholipid profiles
    • 8895838 10.1007/BF02532334 1:CAS:528:DyaK28XmsVejtbw%3D
    • Lukacova N, Halat G, Chavko M, Marsala J (1996) Ischemia- reperfusion injury in the spinal cord of rabbits strongly enhances lipid peroxidation and modifies phospholipid profiles. Neurochem Res 21:869-873
    • (1996) Neurochem Res , vol.21 , pp. 869-873
    • Lukacova, N.1    Halat, G.2    Chavko, M.3    Marsala, J.4
  • 22
    • 0028147386 scopus 로고
    • A new model of diffuse brain injury in rats. Part I: Pathophysiology and biomechanics
    • 8283269 10.3171/jns.1994.80.2.0291 1:STN:280:DyaK2c7htVyquw%3D%3D
    • Marmarou A, Foda MA, van den Brink W, Campbell J, Kita H, Demetriadou K (1994) A new model of diffuse brain injury in rats. Part I: pathophysiology and biomechanics. J Neurosurg 80:291-300
    • (1994) J Neurosurg , vol.80 , pp. 291-300
    • Marmarou, A.1    Foda, M.A.2    Van Den Brink, W.3    Campbell, J.4    Kita, H.5    Demetriadou, K.6
  • 23
    • 0037431041 scopus 로고    scopus 로고
    • Inhibitory effects of 2-mercaptoethane sulfonate and 6-phenylhexyl isothiocyanate on urinary bladder tumorigenesis in rats induced by N-butyl-N-(4-hydroxybutyl) nitrosamine
    • 12691818 10.1016/S0304-3835(02)00097-6 1:CAS:528:DC%2BD3sXis12rsbw%3D
    • Nishikawa A, Morse MA, Chung FL (2003) Inhibitory effects of 2-mercaptoethane sulfonate and 6-phenylhexyl isothiocyanate on urinary bladder tumorigenesis in rats induced by N-butyl-N-(4-hydroxybutyl) nitrosamine. Cancer Lett 193:11-16
    • (2003) Cancer Lett , vol.193 , pp. 11-16
    • Nishikawa, A.1    Morse, M.A.2    Chung, F.L.3
  • 24
    • 0031305389 scopus 로고    scopus 로고
    • Detection of lipid peroxidation and hydroxyl radicals in brain contusion of rats
    • 9416286 1:STN:280:DyaK1c%2FnvVansA%3D%3D
    • Nishio S, Yunoki M, Noguchi Y, Kawauchi M, Asari S, Ohmoto T (1997) Detection of lipid peroxidation and hydroxyl radicals in brain contusion of rats. Acta Neurochir Suppl 70:84-86
    • (1997) Acta Neurochir Suppl , vol.70 , pp. 84-86
    • Nishio, S.1    Yunoki, M.2    Noguchi, Y.3    Kawauchi, M.4    Asari, S.5    Ohmoto, T.6
  • 26
    • 0014108436 scopus 로고
    • Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
    • 6066618 1:CAS:528:DyaF2sXks1Wjur8%3D
    • Paglia DE, Valentine WN (1967) Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 70:158-169
    • (1967) J Lab Clin Med , vol.70 , pp. 158-169
    • Paglia, D.E.1    Valentine, W.N.2
  • 27
    • 2442666466 scopus 로고    scopus 로고
    • Biomarkers of proteolytic damage following traumatic brain injury
    • 15193033 10.1111/j.1750-3639.2004.tb00054.x 1:CAS:528: DC%2BD2cXkvFCgsLw%3D
    • Pineda JA, Wang KK, Hayes RL (2004) Biomarkers of proteolytic damage following traumatic brain injury. Brain Pathol 14:202-209
    • (2004) Brain Pathol , vol.14 , pp. 202-209
    • Pineda, J.A.1    Wang, K.K.2    Hayes, R.L.3
  • 28
    • 0016818865 scopus 로고
    • Malignant transformation-linked imbalance: Decreased XO activity in hepatomas
    • 179860 10.1016/0014-5793(75)80385-1 1:CAS:528:DyaE28XktFKrsg%3D%3D
    • Prajda N, Weber G (1975) Malignant transformation-linked imbalance: decreased XO activity in hepatomas. FEBS Lett 59:245-249
    • (1975) FEBS Lett , vol.59 , pp. 245-249
    • Prajda, N.1    Weber, G.2
  • 29
    • 0030773502 scopus 로고    scopus 로고
    • The time course of malondialdehyde production following impact injury to rat spinal cord as measured by microdialysis and high pressure liquid chromatography
    • 9342727 10.1023/A:1021980929422 1:CAS:528:DyaK2sXmslShurc%3D
    • Qian H, Liu D (1997) The time course of malondialdehyde production following impact injury to rat spinal cord as measured by microdialysis and high pressure liquid chromatography. Neurochem Res 22:1231-1236
    • (1997) Neurochem Res , vol.22 , pp. 1231-1236
    • Qian, H.1    Liu, D.2
  • 31
    • 34247397795 scopus 로고    scopus 로고
    • Mesna or cysteine prevents chloroacetaldehyde-induced cell death of human proximal tubule cells
    • 17273862 10.1007/s00467-006-0414-x
    • Schwerdt G, Kirchhoff A, Freudinger R, Wollny B, Benesic A, Gekle M (2007) Mesna or cysteine prevents chloroacetaldehyde-induced cell death of human proximal tubule cells. Pediatr Nephrol 22:798-803
    • (2007) Pediatr Nephrol , vol.22 , pp. 798-803
    • Schwerdt, G.1    Kirchhoff, A.2    Freudinger, R.3    Wollny, B.4    Benesic, A.5    Gekle, M.6
  • 32
    • 20744457258 scopus 로고    scopus 로고
    • Protective effect of MESNA (2-mercaptoethane sulfonate) against hepatic ischemia/reperfusion injury in rats
    • 15976955 10.1007/s00595-004-2985-0 1:CAS:528:DC%2BD2MXlsFGnt70%3D
    • Sener G, Sehirli O, Ercan F, Sirvanci S, Gedik N, Kacmaz A (2005) Protective effect of MESNA (2-mercaptoethane sulfonate) against hepatic ischemia/reperfusion injury in rats. Surg Today 35:575-580
    • (2005) Surg Today , vol.35 , pp. 575-580
    • Sener, G.1    Sehirli, O.2    Ercan, F.3    Sirvanci, S.4    Gedik, N.5    Kacmaz, A.6
  • 33
    • 0030770947 scopus 로고    scopus 로고
    • Oxidative stress in closed-head injury: Brain antioxidant capacity as an indicator of functional outcome
    • 9346425 10.1097/00004647-199710000-00002 1:CAS:528:DyaK2sXntV2gurY%3D
    • Shohami E, Beit-Yannai E, Horowitz M, Kohen R (1997) Oxidative stress in closed-head injury: brain antioxidant capacity as an indicator of functional outcome. J Cereb Blood Flow Metab 17:1007-1019
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 1007-1019
    • Shohami, E.1    Beit-Yannai, E.2    Horowitz, M.3    Kohen, R.4
  • 34
    • 0023947742 scopus 로고
    • Free radicals in medicine. II. Involvement in human disease
    • 3280885 10.1016/S0025-6196(12)64862-9 1:CAS:528:DyaL1cXitF2lsbw%3D
    • Southorn PA, Powis G (1988) Free radicals in medicine. II. Involvement in human disease. Mayo Clin Proc 63:390-408
    • (1988) Mayo Clin Proc , vol.63 , pp. 390-408
    • Southorn, P.A.1    Powis, G.2
  • 35
    • 0023952554 scopus 로고
    • A simple method for clinical assay of superoxide dismutase
    • 3349599 1:CAS:528:DyaL1cXhvVamt7Y%3D
    • Sun Y, Oberley LW, Li Y (1988) A simple method for clinical assay of superoxide dismutase. Clin Chem 34:497-500
    • (1988) Clin Chem , vol.34 , pp. 497-500
    • Sun, Y.1    Oberley, L.W.2    Li, Y.3
  • 36
    • 0033793630 scopus 로고    scopus 로고
    • Oxidative stress following traumatic brain injury in rats: Quantitation of biomarkers and detection of free radical intermediates
    • 11032908 10.1046/j.1471-4159.2000.0752178.x 1:CAS:528: DC%2BD3cXns1eisrw%3D
    • Tyurin VA, Tyurina YY, Borisenko GG, Sokolova TV, Ritov VB, Quinn PJ, Rose M, Kochanek P, Graham SH, Kagan VE (2000) Oxidative stress following traumatic brain injury in rats: quantitation of biomarkers and detection of free radical intermediates. J Neurochem 75:2178-2189
    • (2000) J Neurochem , vol.75 , pp. 2178-2189
    • Tyurin, V.A.1    Tyurina, Y.Y.2    Borisenko, G.G.3    Sokolova, T.V.4    Ritov, V.B.5    Quinn, P.J.6    Rose, M.7    Kochanek, P.8    Graham, S.H.9    Kagan, V.E.10
  • 37
    • 33645535253 scopus 로고    scopus 로고
    • Modified experimental mild traumatic brain injury model
    • 16531854 10.1097/01.ta.0000209172.75637.db
    • Ucar T, Tanriover G, Gurer I, Onal MZ, Kazan S (2006) Modified experimental mild traumatic brain injury model. J Trauma 60:558-565
    • (2006) J Trauma , vol.60 , pp. 558-565
    • Ucar, T.1    Tanriover, G.2    Gurer, I.3    Onal, M.Z.4    Kazan, S.5
  • 38
    • 0029821355 scopus 로고    scopus 로고
    • Prevention by 2-mercaptoethane sulfonate and N-acetylcysteine of renal oxidative damage in rats treated with ferric nitrilotriacetate
    • 8878448 10.1111/j.1349-7006.1996.tb02115.x 1:CAS:528:DyaK28XlslCku70%3D
    • Umemura T, Hasegawa R, Sai-Kato K, Nishikawa A, Furukawa F, Toyokuni S, Uchida K, Inoue T, Kurokawa Y (1996) Prevention by 2-mercaptoethane sulfonate and N-acetylcysteine of renal oxidative damage in rats treated with ferric nitrilotriacetate. Jpn J Cancer Res 87:882-886
    • (1996) Jpn J Cancer Res , vol.87 , pp. 882-886
    • Umemura, T.1    Hasegawa, R.2    Sai-Kato, K.3    Nishikawa, A.4    Furukawa, F.5    Toyokuni, S.6    Uchida, K.7    Inoue, T.8    Kurokawa, Y.9
  • 39
    • 0034952366 scopus 로고    scopus 로고
    • Effects of nimodipine and magnesium sulfate on endogenous antioxidant levels in brain tissue after experimental head trauma
    • 11426097 10.1097/00008506-200107000-00008
    • Ustün ME, Duman A, Oǧun CO, Vatansev H, Ak A (2001) Effects of nimodipine and magnesium sulfate on endogenous antioxidant levels in brain tissue after experimental head trauma. J Neurosurg Anesthesiol 13:227-232
    • (2001) J Neurosurg Anesthesiol , vol.13 , pp. 227-232
    • Ustün, M.E.1    Duman, A.2    Oǧun, C.O.3    Vatansev, H.4    Ak, A.5
  • 40
    • 0037364149 scopus 로고    scopus 로고
    • Characterization of Bax and Bcl-2 in apoptosis after experimental traumatic brain injury in the rat
    • 12557016 1:CAS:528:DC%2BD3sXntV2htA%3D%3D
    • Wennersten A, Holmin S, Mathiesen T (2003) Characterization of Bax and Bcl-2 in apoptosis after experimental traumatic brain injury in the rat. Acta Neuropathol 105:281-288
    • (2003) Acta Neuropathol , vol.105 , pp. 281-288
    • Wennersten, A.1    Holmin, S.2    Mathiesen, T.3
  • 41
    • 13544251757 scopus 로고    scopus 로고
    • Mechanisms of neural cell death: Implications for development of neuroprotective treatment strategies
    • 15717003 10.1602/neurorx.1.1.5
    • Yakovlev AG, Faden AI (2004) Mechanisms of neural cell death: implications for development of neuroprotective treatment strategies. NeuroRx 1:5-16
    • (2004) NeuroRx , vol.1 , pp. 5-16
    • Yakovlev, A.G.1    Faden, A.I.2
  • 42
    • 4143132484 scopus 로고    scopus 로고
    • Mesna ameliorates intestinal mucosa damage after ifosfamide administration in the rabbit at a dose-related manner
    • 15313380 10.1016/j.jss.2004.03.003 1:CAS:528:DC%2BD2cXmslalsrk%3D
    • Ypsilantis P, Tentes I, Assimakopoulos SF, Kortsaris A, Scopa CD, Simopoulos C (2004) Mesna ameliorates intestinal mucosa damage after ifosfamide administration in the rabbit at a dose-related manner. J Surg Res 121:84-91
    • (2004) J Surg Res , vol.121 , pp. 84-91
    • Ypsilantis, P.1    Tentes, I.2    Assimakopoulos, S.F.3    Kortsaris, A.4    Scopa, C.D.5    Simopoulos, C.6


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