TNF-α-mediated NF-κB survival signaling impairment by cisplatin enhances JNK activation allowing synergistic apoptosis of renal proximal tubular cells

Biochemical Pharmacology

Volumn 85, Issue 2, 2013, Pages 274-286

  Benedetti, Giulia ^a   Fredriksson, Lisa ^a   Herpers, Bram ^a   Meerman, John ^a   Van De Water, Bob ^a   De Graauw, Marjo ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Cisplatin; JNK; Nephrotoxicity; NF B; TNF

Indexed keywords

CISPLATIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL IMMORTALIZATION; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; EPITHELIUM CELL; FEEDBACK SYSTEM; GENE EXPRESSION; GENETIC TRANSCRIPTION; IN VIVO STUDY; INFLAMMATION; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; NEPHROTOXICITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SURVIVAL RATE; TRANSCRIPTOMICS;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TRANSFORMED; CISPLATIN; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENES, REPORTER; KIDNEY TUBULES, PROXIMAL; MAP KINASE SIGNALING SYSTEM; MICE; NF-KAPPA B; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84872033024     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.10.012     Document Type: Article

References (59)

1. S.M. Cohen, and S.J. Lippard Cisplatin: from DNA damage to cancer chemotherapy Prog Nucl Acid Res Mol Biol 67 2001 93 130
2. I. Arany, and R.L. Safirstein Cisplatin nephrotoxicity Semin Nephrol 23 2003 460 464
3. N. Pabla, and Z. Dong Cisplatin nephrotoxicity: mechanisms and renoprotective strategies Kidney Int 73 2008 994 1007
4. X. Yao, K. Panichpisal, N. Kurtzman, and K. Nugent Cisplatin nephrotoxicity: a review Am J Med Sci 334 2007 115 124
5. B. Zhang, G. Ramesh, C.C. Norbury, and W.B. Reeves Cisplatin-induced nephrotoxicity is mediated by tumor necrosis factor-alpha produced by renal parenchymal cells Kidney Int 72 2007 37 44
6. G. Ramesh, and W. Brian Reeves Cisplatin increases TNF-alpha mRNA stability in kidney proximal tubule cells Ren Fail 28 2006 583 592
7. G. Ramesh, S.R. Kimball, L.S. Jefferson, and W.B. Reeves Endotoxin and cisplatin synergistically stimulate TNF-alpha production by renal epithelial cells Am J Physiol Renal Physiol 292 2007 F812 F819
8. M. Liu, C.C. Chien, M. Burne-Taney, R.R. Molls, L.C. Racusen, and R.B. Colvin A pathophysiologic role for T lymphocytes in murine acute cisplatin nephrotoxicity J Am Soc Nephrol 17 2006 765 774
9. A. Hoffmann, and D. Baltimore Circuitry of nuclear factor kappaB signaling Immunol Rev 210 2006 171 186
10. O. Micheau, and J. Tschopp Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes Cell 114 2003 181 190
11. Y. Deng, X. Ren, L. Yang, Y. Lin, and X. Wu A JNK-dependent pathway is required for TNFalpha-induced apoptosis Cell 115 2003 61 70
12. A. Wullaert, K. Heyninck, and R. Beyaert Mechanisms of crosstalk between TNF-induced NF-kappaB and JNK activation in hepatocytes Biochem Pharmacol 72 2006 1090 1101
13. L. Fredriksson, B. Herpers, G. Benedetti, Q. Matadin, J.C. Puigvert, and H. de Bont Diclofenac inhibits tumor necrosis factor-alpha-induced nuclear factor-kappaB activation causing synergistic hepatocyte apoptosis Hepatology 53 2011 2027 2041
14. G. Ramesh, and W.B. Reeves TNF-alpha mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity J Clin Invest 110 2002 835 842
15. J.C. Puigvert, H. de Bont, B. van de Water, and E.H. Danen High-throughput live cell imaging of apoptosis Curr Protoc Cell Biol 18 2010 [Chapter 18:Unit 18 0 1-3]
16. G. Stokman, Y. Qin, H.G. Genieser, F. Schwede, E. de Heer, and J.L. Bos Epac-Rap signaling reduces cellular stress and ischemia-induced kidney failure J Am Soc Nephrol 22 2011 859 872
17. M. de Graauw, I. Tijdens, R. Cramer, S. Corless, J.F. Timms, and B. van de Water Heat shock protein 27 is the major differentially phosphorylated protein involved in renal epithelial cellular stress response and controls focal adhesion organization and apoptosis J Biol Chem 280 2005 29885 29898
18. Y. Benjamini, and Y. Hochberg Controlling the false discovery rate: a practical and powerful approach to multiple testing J Roy Stat Soc Ser B (Methodol) 57 1995 289 300
19. D.P. Kelsen, N. Alcock, and C.W. Young Cisplatin nephrotoxicity. Correlation with plasma platinum concentrations Am J Clin Oncol 8 1985 77 80
20. E.E. Brouwers, A.D. Huitema, J.H. Beijnen, and J.H. Schellens Long-term platinum retention after treatment with cisplatin and oxaliplatin BMC Clin Pharmacol 8 2008 7
21. J.V. Bonventre, V.S. Vaidya, R. Schmouder, P. Feig, and F. Dieterle Next-generation biomarkers for detecting kidney toxicity Nat Biotechnol 28 2010 436 440
22. P.H. Wang, M.A. Cenedeze, J.B. Pesquero, A. Pacheco-Silva, and N.O. Camara Influence of bradykinin B1 and B2 receptors in the immune response triggered by renal ischemia-reperfusion injury Int Immunopharmacol 6 2006 1960 1965
23. G.M. Mulder, W.N. Nijboer, M.A. Seelen, M. Sandovici, E.M. Bos, and W.B. Melenhorst Heparin binding epidermal growth factor in renal ischaemia/ reperfusion injury J Pathol 221 2010 183 192
24. C.F. Cheng, and H. Lin Acute kidney injury and the potential for ATF3-regulated epigenetic therapy Toxicol Mech Methods 21 2011 362 366
25. Y. Bauer, P. Hess, C. Qiu, A. Klenk, B. Renault, and D. Wanner Identification of cathepsin L as a potential sex-specific biomarker for renal damage Hypertension 57 2011 795 801
26. F. Gueler, S. Rong, M. Mengel, J.K. Park, J. Kiyan, and T. Kirsch Renal urokinase-type plasminogen activator (uPA) receptor but not uPA deficiency strongly attenuates ischemia reperfusion injury and acute kidney allograft rejection J Immunol 181 2008 1179 1189
27. T. Nakamura, E. Sato, N. Fujiwara, Y. Kawagoe, H. Koide, and Y. Ueda Calcium channel blocker inhibition of AGE and RAGE axis limits renal injury in nondiabetic patients with stage I or II chronic kidney disease Clin Cardiol 34 2011 372 377
28. T. Eleftheriadis, G. Antoniadi, V. Liakopoulos, N. Antoniadis, I. Stefanidis, and G. Galaktidou Vitamin D receptor activators and response to injury in kidney diseases J Nephrol 23 2010 514 524
29. P. Duann, and E.A. Lianos Mechanisms of HO-1 mediated attenuation of renal immune injury: a gene profiling study Transl Res 158 2011 249 261
30. Q. Wei, W.D. Hill, Y. Su, S. Huang, and Z. Dong Heme oxygenase-1 induction contributes to renoprotection by G-CSF during rhabdomyolysis- associated acute kidney injury Am J Physiol Renal Physiol 301 2011 F162 F170
31. S. Mitazaki, S. Honma, M. Suto, N. Kato, K. Hiraiwa, and M. Yoshida Interleukin-6 plays a protective role in development of cisplatin-induced acute renal failure through upregulation of anti-oxidative stress factors Life Sci 88 2011 1142 1148
32. Y. Motoyoshi, T. Matsusaka, A. Saito, I. Pastan, T.E. Willnow, and S. Mizutani Megalin contributes to the early injury of proximal tubule cells during nonselective proteinuria Kidney Int 74 2008 1262 1269
33. S. Shibata, and T. Fujita Mineralocorticoid receptors in the pathophysiology of chronic kidney diseases and the metabolic syndrome Mol Cell Endocrinol 350 2 2011 273 280
34. J.R. Timoshanko, A.R. Kitching, T.J. Semple, S.R. Holdsworth, and P.G. Tipping Granulocyte macrophage colony-stimulating factor expression by both renal parenchymal and immune cells mediates murine crescentic glomerulonephritis J Am Soc Nephrol 16 2005 2646 2656
35. B. Lucas, K. Grigo, S. Erdmann, J. Lausen, L. Klein-Hitpass, and G.U. Ryffel HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma Oncogene 24 2005 6418 6431
36. H.B. Schonthaler, J. Guinea-Viniegra, and E.F. Wagner Targeting inflammation by modulating the Jun/AP-1 pathway Ann Rheum Dis 70 Suppl. 1 2011 i109 i112
37. J.R. Schultz-Norton, Y.S. Ziegler, and A.M. Nardulli ERalpha-associated protein networks Trends Endocrinol Metab 22 2011 124 129
38. A.Y. Wen, K.M. Sakamoto, and L.S. Miller The role of the transcription factor CREB in immune function J Immunol 185 2010 6413 6419
39. P. May, and E. May Twenty years of p53 research: structural and functional aspects of the p53 protein Oncogene 18 1999 7621 7636
40. N.D. Perkins Integrating cell-signalling pathways with NF-kappaB and IKK function Nat Rev Mol Cell Biol 8 2007 49 62
41. J. Hess, P. Angel, and M. Schorpp-Kistner AP-1 subunits: quarrel and harmony among siblings J Cell Sci 117 2004 5965 5973
42. I. Arany, J.K. Megyesi, H. Kaneto, P.M. Price, and R.L. Safirstein Cisplatin-induced cell death is EGFR/src/ERK signaling dependent in mouse proximal tubule cells Am J Physiol Renal Physiol 287 2004 F543 F549
43. H.D. Francescato, R.S. Costa, F.B. Junior, and T.M. Coimbra Effect of JNK inhibition on cisplatin-induced renal damage Nephrol Dial Transplant 22 2007 2138 2148
44. M.S. Hayden, and S. Ghosh Shared principles in NF-kappaB signaling Cell 132 2008 344 362
45. G. Tang, Y. Minemoto, B. Dibling, N.H. Purcell, Z. Li, and M. Karin Inhibition of JNK activation through NF-kappaB target genes Nature 414 2001 313 317
46. C. Bubici, S. Papa, C.G. Pham, F. Zazzeroni, and G. Franzoso NF-kappaB and JNK: an intricate affair Cell Cycle 3 2004 1524 1529
47. E. De Smaele, F. Zazzeroni, S. Papa, D.U. Nguyen, R. Jin, and J. Jones Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling Nature 414 2001 308 313
48. D. Kesanakurti, C. Chetty, P. Bhoopathi, S.S. Lakka, B. Gorantla, and A.J. Tsung Suppression of MMP-2 attenuates TNF-alpha induced NF-kappaB activation and leads to JNK mediated cell death in glioma PLoS ONE 6 2011 e19341
49. Y.H. Lee, and W.P. Schiemann Fibromodulin suppresses nuclear factor-kappaB activity by inducing the delayed degradation of IKBA via a JNK-dependent pathway coupled to fibroblast apoptosis J Biol Chem 286 2011 6414 6422
50. M. Kruidering, B. van de Water, Y. Zhan, J.J. Baelde, E. Heer, and G.J. Mulder Cisplatin effects on F-actin and matrix proteins precede renal tubular cell detachment and apoptosis in vitro Cell Death Differ 5 1998 601 614
51. Y. Qin, G. Stokman, K. Yan, S. Ramaiahgari, F. Verbeek, and M. de Graauw cAMP signalling protects proximal tubular epithelial cells from cisplatin-induced apoptosis via activation of Epac Br J Pharmacol 165 2012 1137 1150
52. C.V. Thakar, K. Zahedi, M.P. Revelo, Z. Wang, C.E. Burnham, and S. Barone Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney ischemia J Clin Invest 115 2005 3451 3459
53. A. Lu, M. Miao, T.R. Schoeb, A. Agarwal, and J.E. Murphy-Ullrich Blockade of TSP1-dependent TGF-beta activity reduces renal injury and proteinuria in a murine model of diabetic nephropathy Am J Pathol 178 2011 2573 2586
54. X. Peng, W. Li, and G. Tan Reversal of taxol resistance by cisplatin in nasopharyngeal carcinoma by upregulating thromspondin-1 expression Anticancer Drugs 21 2010 381 388
55. B. Xu, P. Liu, J. Li, and H. Lu c-MYC depletion potentiates cisplatin-induced apoptosis in head and neck squamous cell carcinoma: involvement of TSP-1 up-regulation Ann Oncol 21 2010 670 672
56. H. Nakano, A. Nakajima, S. Sakon-Komazawa, J.H. Piao, X. Xue, and K. Okumura Reactive oxygen species mediate crosstalk between NF-kappaB and JNK Cell Death Differ 13 2006 730 737
57. A. Ariga, J. Namekawa, N. Matsumoto, J. Inoue, and K. Umezawa Inhibition of tumor necrosis factor-alpha-induced nuclear translocation and activation of NF-kappa B by dehydroxymethylepoxyquinomicin J Biol Chem 277 2002 24625 24630
58. L.F. Pemberton, and B.M. Paschal Mechanisms of receptor-mediated nuclear import and nuclear export Traffic 6 2005 187 198
59. W. Xiao, D.R. Hodge, L. Wang, X. Yang, X. Zhang, and W.L. Farrar NF-kappaB activates IL-6 expression through cooperation with c-Jun and IL6-AP1 site, but is independent of its IL6-NFkappaB regulatory site in autocrine human multiple myeloma cells Cancer Biol Ther 3 2004 1007 1017