The effect of ascorbic acid on proliferation of vascular smooth muscle cells and intimal hyperplasia;Askorbik Asidin Anastomoz Sonrasi Gelisen Vasküler Düz Kas Hücre Proliferasyonu ve Intimal Hiperplazi Üzerine Etkisi: Tavsan Modeli

Turkiye Klinikleri Journal of Medical Sciences

Volumn 33, Issue 1, 2013, Pages 126-131

  Gökalp, Orhan ^a   Yürekli, Ismail ^b   Mavioglu, Levent ^c   Kiray, Müge ^d   Bagriyanik, Alper ^d   Kestelli, Mert ^b   Tetik, Ömer ^e   Yilik, Levent ^b   Gürbüz, Ali ^a  

^a IZMIR KATIP CELEBI UNIVERSITY   (Turkey)

^b Izmir Ataturk Training and Research Hospital   (Turkey)

^c Acibadem Hospital   (Turkey)

^d DOKUZ EYLUL UNIVERSITY   (Turkey)

^e BURSA YUKSEK IHTISAS TRAINING AND RESEARCH HOSPITAL   (Turkey)

Author keywords

Ascorbic acid; Hyperplasia; Muscle; Smooth

Indexed keywords

ASCORBIC ACID; EOSIN; FORMALDEHYDE; HEMATOXYLIN; PARAFFIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTERY MEDIA; ARTICLE; BLOOD VESSEL DIAMETER; CAROTID ARTERY; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HISTOPATHOLOGY; MALE; MORPHOMETRICS; MUSCLE CELL; NONHUMAN; RABBIT; VASCULAR SMOOTH MUSCLE;

EID: 84872031858     PISSN: 13000292     EISSN: None     Source Type: Journal    
DOI: 10.5336/medsci.2012-29406     Document Type: Article

References (23)

1. Göncü T, Tiryakioǧlu O, Ozcan A, Ari H, Sezen M, Vural H, et al. Inhibitory effects of ticlopidine and clopidogrel on the intimal hyperplastic response after arterial injury. Anadolu Kardiyol Derg 2010;10(1):11-6.
2. Reel B, Çavdar Z, Ergür BU, Özkal S, Özşarlak-Sözer G, Oktay G, et al. [Endothelin receptor-independent correlation between HSP47 and collagen in rabbit model of early atherosclerosis]. Turkiye Klinikleri J Med Sci 2011;31(6):1330-9.
3. Esrefoǧlu M. [Cell injury and death: oxidative stress and antioxidant defense system: review]. Turkiye Klinikleri J Med Sci 2009; 29(6):1660-76.
4. Göncü T, Yavuz Ş, Çekirdekçi A, Karaca I, Özercan İ. [The effect of perindopril on the intimal hyperplasia occurring after vascular injury]. Turkish J Thorac Cardiovasc Surg 2001;9 (2):109-14.
5. Hagen PO, Davies MG, Schuman RW, Murray JJ. Reduction of vein graft intimal hyperplasia by ex vivo treatment with desferrioxamine manganese. J Vasc Res 1992;29(6):405-9.
6. Gokce G, Ozsarlak G, Oran I, Oktay G, Ozkal S, Kerry Z. The role of oxidative stress on intimal hyperplasia: modulation of lox-1 expression by taurine. Atherosclerosis 2008; 9(1):58-9.
7. Huynh TT, Davies MG, Trovato MJ, Barber L, Safi HJ, Hagen PO. Reduction of lipid peroxidation with intraoperative superoxide dismutase treatment decreases intimal hyperplasia in experimental vein grafts. J Surg Res 1999;84(2):223-32.
8. Takiguchi Y, Nagano M, Ikeda Y, Nakashima M. Early administration of YT-146, an adenosine A2 receptor agonist, inhibits neointimal thickening after rat femoral artery endothelium injury. Eur J Pharmacol 1995;281(2):205-7.
9. Miyake T, Aoki M, Morishita R. Inhibition of anastomotic intimal hyperplasia using a chimeric decoy strategy against NFkappaB and E2F in a rabbit model. Cardiovasc Res 2008;79(4):706-14.
10. More RS, Rutty G, Underwood MJ, Brack MJ, Gershlick AH. A time sequence of vessel wall changes in an experimental model of angioplasty. J Pathol 1994;172(3):287-92.
11. Reel B, Oktay G, Ozkal S, Islekel H, Ozer E, Ozsarlak-Sozer G, et al. MMP-2 and MMP-9 alteration in response to collaring in rabbits: the effects of endothelin receptor antagonism. J Cardiovasc Pharmacol Ther 2009;14(4):292-301.
12. Asada Y, Kisanuki A, Tsuneyoshi A, Marutsuka K, Hatakeyama K, Sumiyoshi A. Effects of inflation pressure of balloon catheter on vascular injuries and subsequent development of intimal hyperplasia in rabbit aorta. Atherosclerosis 1996;121(1):45-53.
13. Sullivan TR Jr, Karas RH, Aronovitz M, Faller GT, Ziar JP, Smith JJ, et al. Estrogen inhibits the response-to-injury in a mouse carotid artery model. J Clin Invest 1995;96(5):2482-8.
14. Duarte TL, Lunec J. Review: When is an antioxidant not an antioxidant? A review of novel actions and reactions of vitamin C. Review: When is an antioxidant not an antioxidant? A review of novel actions and reactions of vitamin C. Free Radic Res 2005;39(7):671-86.
15. Lykkesfeldt J, Poulsen HE. Is vitamin C supplementation beneficial? Lessons learned from randomised controlled trials. Br J Nutr 2010;103(9):1251-9.
16. Chen X, Touyz RM, Park JB, Schiffrin EL. Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR. Hypertension 2001;38(3 Pt 2):606-11.
17. Duvall WL. Endothelial dysfunction and antioxidants. Mt Sinai J Med 2005;72(2):71-80.
18. Casciari JJ, Riordan NH, Schmidt TL, Meng XL, Jackson JA, Riordan HD. Cytotoxicity of ascorbate, lipoic acid, and other antioxidants in hollow fibre in vitro tumours. Br J Cancer 2001;84(11):1544-50.
19. Agus DB, Vera JC, Golde DW. Stromal cell oxidation: a mechanism by which tumors obtain vitamin C. Cancer Res 1999;59(18): 4555-8.
20. Reel B. [Matrix metalloproteinases and atherosclerosis: review]. Turkiye Klinikleri J Med Sci 2006; 26(5):527-37.
21. Ivanov V, Roomi MW, Kalinovsky T, Niedzwiecki A, Rath M. Anti-atherogenic effects of a mixture of ascorbic acid, lysine, proline, arginine, cysteine, and green tea phenolics in human aortic smooth muscle cells. J Cardiovasc Pharmacol 2007;49(3): 140-5.
22. Ivanov VO, Ivanova SV, Niedzwiecki A. Ascorbate affects proliferation of guinea-pig vascular smooth muscle cells by direct and extracellular matrix-mediated effects. J Mol Cell Cardiol 1997;29(12):3293-303.
23. Arakawa E, Hasegawa K, Irie J, Ide S, Ushiki J, Yamaguchi K, et al. L-ascorbic acid stimulates expression of smooth muscle-specific markers in smooth muscle cells both in vitro and in vivo. J Cardiovasc Pharmacol 2003;42(6):745-51.