Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1

Biochemical Pharmacology

Volumn 85, Issue 2, 2013, Pages 234-244

  Khare, Vineeta ^a   Lyakhovich, Alex ^a,d   Dammann, Kyle ^a   Lang, Michaela ^a   Borgmann, Melanie ^a   Tichy, Boris ^b   Pospisilova, Sarka ^b   Luciani, Gloria ^a,e   Campregher, Christoph ^a   Evstatiev, Rayko ^a   Pflueger, Maren ^c   Hundsberger, Harald ^c   Gasche, Christoph ^a,d  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY HOSPITAL BRNO   (Czech Republic)

^c IMC UNIVERSITY OF APPLIED SCIENCES KREMS   (Austria)

^d DUKE NUS MEDICAL SCHOOL   (Singapore)

^e CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

Author keywords

Beta catenin; Cell adhesion; E cadherin; Mesalamine; PAK1

Indexed keywords

APC PROTEIN; BETA CATENIN; CYCLIN D1; MESALAZINE; MYC PROTEIN; P21 ACTIVATED KINASE 1; SCATTER FACTOR RECEPTOR; TRANSCRIPTION FACTOR CDX1; UVOMORULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ADHESION; CELL PROLIFERATION; CELL STRAIN HT29; COLORECTAL CARCINOMA; CONTROLLED STUDY; DISEASE COURSE; DOSE RESPONSE; ENZYME INHIBITION; FEMALE; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LOW DRUG DOSE; MALE; MICROARRAY ANALYSIS; MODULATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RNA INTERFERENCE; WNT SIGNALING PATHWAY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTICARCINOGENIC AGENTS; BETA CATENIN; CADHERINS; CELL ADHESION; CELL LINE, TUMOR; COLONIC NEOPLASMS; DOWN-REGULATION; FEMALE; GENE EXPRESSION PROFILING; HUMANS; INTESTINAL POLYPS; MALE; MAP KINASE SIGNALING SYSTEM; MESALAMINE; MICE; NEOPLASM PROTEINS; P21-ACTIVATED KINASES; RNA INTERFERENCE; WNT SIGNALING PATHWAY;

EID: 84872026149     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.10.026     Document Type: Article

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