Increased red blood cell deformability and decreased aggregation as potential adaptive mechanisms in the slow coronary flow phenomenon

Coronary Artery Disease

Volumn 24, Issue 1, 2013, Pages 11-15

  Yaylali, Yalin Tolga ^a   Susam, Ibrahim ^b   Demir, Erdem ^c   Bor Kucukatay, Melek ^a   Uludag, Burcu ^a   Kilic Toprak, Emine ^a   Erken, Gulten ^d   Dursunoglu, Dursun ^a  

^a PAMUKKALE UNIVERSITY   (Turkey)

^b Tepecik Training and Research Hospital ^*  (Turkey)

^c Sandikli State Hospital   (Turkey)

^d BALIKESIR UNIVERSITY   (Turkey)

Author keywords

chest pain symptoms; coronary artery disease; plasma viscosity; rheological factors; whole blood viscosity

Indexed keywords

ADULT; ANGIOGRAPHY; ARTICLE; BLOOD CLOT LYSIS; BLOOD RHEOLOGY; BLOOD VISCOSITY; CLINICAL ASSESSMENT TOOL; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; ERYTHROCYTE AGGREGATION; ERYTHROCYTE DEFORMABILITY; FEMALE; HALF LIFE TIME; HEART INFARCTION; HEMATOCRIT; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SHEAR STRESS; SLOW CORONARY FLOW PHENOMENON;

ADAPTATION, PHYSIOLOGICAL; BLOOD VISCOSITY; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CINEANGIOGRAPHY; CORONARY ANGIOGRAPHY; CORONARY CIRCULATION; ERYTHROCYTE AGGREGATION; ERYTHROCYTE DEFORMABILITY; FEMALE; HEMATOCRIT; HUMANS; MALE; MIDDLE AGED; NO-REFLOW PHENOMENON;

EID: 84872017797     PISSN: 09546928     EISSN: 14735830     Source Type: Journal    
DOI: 10.1097/MCA.0b013e32835b0bdf     Document Type: Article

References (23)

1. Tambe AA, Demany MA, Zimmerman HA, Mascarenhas E. Angina pectoris and slow flow velocity of dye in coronary arteries - a new angiographic finding. Am Heart J 1972; 84:66-71.
2. Beltrame JF, Limaye SB, Horowitz JD. The coronary slow flow phenomenon - a new coronary microvascular disorder. Cardiology 2002; 97:197-202.
3. Mangieri E, Macchiarelli G, Ciavolella M, Barilla' F, Avella A, Martinotti A, et al. Slow coronary flow: clinical and histopathological features in patients with otherwise normal epicardial coronary arteries. Cathet Cardiovasc Diagn 1996; 37:375-381.
4. Barshtein G, Ben-Ami R, Yedgar S. Role of red blood cell flow behavior in hemodynamics and hemostasis. Expert Rev Cardiovasc Ther 2007; 5:743-752.
5. Bla'ha M, Rencová E, Bla'ha V, Malý R, Blazek M, Studnicka J, et al. The importance of rheological parameters in the therapy of microcirculatory disorders. Clin Hemorheol Microcirc 2009; 42:37-46.
6. Marossy A, Svorc P, Kron I, Gresová S. Hemorheology and circulation. Clin Hemorheol Microcirc 2009; 42:239-258.
7. Gibson CM, Cannon CP, Daley WL, Dodge JT Jr, Alexander B Jr, Marble SJ, et al. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation 1996; 93:879-888.
8. Hardeman MR, Goedhart PT, Dobbe JGG, Lettinga KP. Laser-assisted optical rotational cell analyzer (LORCA): a new instrument for measurement of various structural hemorheological parameters. Clin Hemorheol 1994; 14:605-618.
9. Hardeman MR, Dobbe JG, Ince C. The Laser-assisted Optical Rotational Cell Analyzer (LORCA) as red blood cell aggregometer. Clin Hemorheol Microcirc 2001; 25:1-11.
10. Beltrame JF, Turner SP, Leslie SL, Solomon P, Freedman SB, Horowitz JD. The angiographic and clinical benefits of mibefradil in the coronary slow flow phenomenon. J Am Coll Cardiol 2004; 44:57-62.
11. Fineschi M, Bravi A, Gori T. The 'slow coronary flow' phenomenon: evidence of preserved coronary flow reserve despite increased resting microvascular resistances. Int J Cardiol 2008; 127:358-361.
12. Muxel S, Fasola F, Radmacher MC, Jabs A, Mu? nzel T, Gori T. Endothelial functions: translating theory into clinical application. Clin Hemorheol Microcirc 2010; 45:109-115.
13. Leone MC, Gori T, Fineschi M. The coronary slow flow phenomenon: a new cardiac 'Y' syndrome? Clin Hemorheol Microcirc 2008; 39:185-190.
14. Lowe G, Rumley A, Norrie J, Ford I, Shepherd J, Cobbe S. Blood rheology, cardiovascular risk factors, and cardiovascular disease: the West of Scotland Coronary Prevention Study. Thromb Haemost 2000; 84: 553-558.
15. Mohandas N, Chasis JA, Shohet SB. The influence of membrane skeleton on red cell deformability, membrane material properties, and shape. Semin Hematol 1983; 20:225-242.
16. Chien S. Biophysical behavior of red cells in suspensions. In: Surgenor DM, editor. The red blood cell. New York, NY: Academic Press; 1975; p. 1031.
17. Baskurt OK, Meiselman HJ. Blood rheology and hemodynamics. Semin Thromb Hemost 2003; 29:435-450.
18. Ergun-Cagli K, Ileri-Gurel E, Ozeke O, Seringec N, Yalcinkaya A, Kocabeyoglu S, et al. Blood viscosity changes in slow coronary flow patients. Clin Hemorheol Microcirc 2011; 47:27-35.
19. Bilgi M, Gullu H, Kozanoglu I, Ozdogu H, Sezgin N, Sezgin AT, et al. Evaluation of blood rheology in patients with coronary slow flow or non-obstructive coronary artery disease. Clin Hemorheol Microcirc 2012. [Epub ahead of print]
20. Kurtoglu N, Akcay A, Dindar I. Usefulness of oral dipyridamole therapy for angiographic slow coronary artery flow. Am J Cardiol 2001; 87:777-779.
21. Albayrak S, Ordu S, Yuksel H, Ozhan H, Yazgan O, Yazici M. Efficacy of nebivolol on flow-mediated dilation in patients with slow coronary flow. Int Heart J 2009; 50:545-553.
22. Topal E, Ozdemir R, Barutcu I, Aksoy Y, Sincer I, Akturk E, et al. The effects of trimetazidine on heart rate variability in patients with slow coronary artery flow. J Electrocardiol 2006; 39:211-218.
23. Caliskan M, Erdogan D, Gullu H, Topcu S, Ciftci O, Yildirir A, et al. Effects of atorvastatin on coronary flow reserve in patients with slow coronary flow. Clin Cardiol 2007; 30:475-479.