The "slow coronary flow" phenomenon: Evidence of preserved coronary flow reserve despite increased resting microvascular resistances

International Journal of Cardiology

Volumn 127, Issue 3, 2008, Pages 358-361

  Fineschi, Massimo ^b   Bravi, Achille ^b   Gori, Tommaso ^a,b  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY HOSPITAL OF SIENA   (Italy)

Author keywords

Coronary angiography; Coronary flow reserve; Coronary slow flow phenomenon; Microcirculation

Indexed keywords

ADULT; AGED; ANGINA PECTORIS; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY FLOW RESERVE; ELECTROCARDIOGRAM; FEMALE; HEART RATE; HUMAN; IN VIVO STUDY; MALE; PRIORITY JOURNAL; VASCULAR RESISTANCE;

AGED; ANGINA, UNSTABLE; BLOOD FLOW VELOCITY; COLLATERAL CIRCULATION; CORONARY ARTERY DISEASE; CORONARY CIRCULATION; CORONARY VESSELS; FEMALE; HUMANS; MALE; MICROCIRCULATION; MIDDLE AGED; VASOCONSTRICTION;

EID: 45849091182     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2007.06.010     Document Type: Article

References (17)

1. Pekdemir H., Cin V.G., Cicek D., et al. Slow coronary flow may be a sign of diffuse atherosclerosis. Contribution of FFR and IVUS. Acta Cardiol 59 (2004) 127-133
2. Sezgin A.T., Topal E., Barutcu I., et al. Impaired left ventricle filling in slow coronary flow phenomenon: an echo-Doppler study. Angiology 56 (2005) 397-401
3. Sezgin N., Barutcu I., Sezgin A.T., et al. Plasma nitric oxide level and its role in slow coronary flow phenomenon. Int Heart J 46 (2005) 373-382
4. Erdogan D., Caliskan M., Gullu H., et al. Coronary flow reserve is impaired in patients with slow coronary flow. Atherosclerosis 191 1 (2007) 168-174
5. Gibson C.M., Cannon C.P., Daley W.L., et al. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation 93 (1996) 879-888
6. Ng M.K., Yeung A.C., and Fearon W.F. Invasive assessment of the coronary microcirculation: superior reproducibility and less hemodynamic dependence of index of microcirculatory resistance compared with coronary flow reserve. Circulation 113 (2006) 2054-2061
7. Fearon W.F., Balsam L.B., Farouque H.M., et al. Novel index for invasively assessing the coronary microcirculation. Circulation 107 (2003) 3129-3132
8. Pijls N.H., Van Gelder B., van d V., et al. Fractional flow reserve. A useful index to evaluate the influence of an epicardial coronary stenosis on myocardial blood flow. Circulation 92 (1995) 3183-3193
9. Beltrame J.F., Limaye S.B., and Horowitz J.D. The coronary slow flow phenomenon-a new coronary microvascular disorder. Cardiology 97 (2002) 197-202
10. Singh S., Kothari S.S., and Bahl V.K. Coronary slow flow phenomenon: an angiographic curiosity. Indian Heart J 56 (2004) 613-617
11. Tanriverdi H., Evrengul H., Enli Y., et al. Effect of homocysteine-induced oxidative stress on endothelial function in coronary slow-flow. Cardiology 107 (2007) 313-320
12. Sezgin A.T., Sigirci A., Barutcu I., et al. Vascular endothelial function in patients with slow coronary flow. Coron Artery Dis 14 (2003) 155-161
13. Cokkinos D.V., Manginas A., and Voudris V. Coronary flow: clinical considerations. Heart 89 (2003) 361-363
14. Beltrame J.F., Limaye S.B., Wuttke R.D., et al. Coronary hemodynamic and metabolic studies of the coronary slow flow phenomenon. Am Heart J 146 (2003) 84-90
15. Mangieri E., Macchiarelli G., Ciavolella M., et al. Slow coronary flow: clinical and histopathological features in patients with otherwise normal epicardial coronary arteries. Cathet Cardiovasc Diagn 37 (1996) 375-381
16. Celik T., Iyisoy A., Kursaklioglu H., et al. ST elevation during treadmill exercise test in a young patient with slow coronary flow: a case report and review of literature. Int J Cardiol 112 (2006) e1-e4
17. Bugiardini R., and Bairey Merz C.N. Angina with "normal" coronary arteries: a changing philosophy. JAMA 293 (2005) 477-484