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Volumn 18, Issue 1, 2013, Pages 42-47

Pharmacological treatment of neonatal pain: In search of a new equipoise

Author keywords

Loco regional anesthesia; Morphine; Neuro apoptosis; Newborn; Pain; Paracetamol

Indexed keywords

ANESTHETIC AGENT; MORPHINE; PARACETAMOL; REMIFENTANIL; TRAMADOL;

EID: 84871935308     PISSN: 1744165X     EISSN: 18780946     Source Type: Journal    
DOI: 10.1016/j.siny.2012.10.001     Document Type: Review
Times cited : (38)

References (55)
  • 1
    • 0023627371 scopus 로고
    • Pain and its effects in the human neonate and fetus
    • Anand K.J., Hickey P.R. Pain and its effects in the human neonate and fetus. N Engl J Med 1987, 317:1321-1329.
    • (1987) N Engl J Med , vol.317 , pp. 1321-1329
    • Anand, K.J.1    Hickey, P.R.2
  • 3
    • 84856515290 scopus 로고    scopus 로고
    • Pediatric analgesic clinical trial designs, measures, and extrapolation: report of an FDA scientific workshop
    • Berde C.B., Walco G.A., Krane E.J., et al. Pediatric analgesic clinical trial designs, measures, and extrapolation: report of an FDA scientific workshop. Pediatrics 2012, 129:354-364.
    • (2012) Pediatrics , vol.129 , pp. 354-364
    • Berde, C.B.1    Walco, G.A.2    Krane, E.J.3
  • 4
    • 58249137363 scopus 로고    scopus 로고
    • Drugs of choice for sedation and analgesia in the neonatal ICU
    • Hall R.W., Shbarou R.M. Drugs of choice for sedation and analgesia in the neonatal ICU. Clin Perinatol 2009, 36:215-226.
    • (2009) Clin Perinatol , vol.36 , pp. 215-226
    • Hall, R.W.1    Shbarou, R.M.2
  • 6
    • 79956313437 scopus 로고    scopus 로고
    • Analgosedation in neonates: do we still need additional tools after 30 years of clinical research?
    • Thewissen L., Allegaert K. Analgosedation in neonates: do we still need additional tools after 30 years of clinical research?. Arch Dis Child Educ Pract Ed 2011, 96:112-118.
    • (2011) Arch Dis Child Educ Pract Ed , vol.96 , pp. 112-118
    • Thewissen, L.1    Allegaert, K.2
  • 8
    • 84861376796 scopus 로고    scopus 로고
    • The pain-free ward: myth or reality
    • Morton N.S. The pain-free ward: myth or reality. Paediatr Anaesth 2012, 22:527-529.
    • (2012) Paediatr Anaesth , vol.22 , pp. 527-529
    • Morton, N.S.1
  • 9
    • 79958141555 scopus 로고    scopus 로고
    • Anesthesia and neurotoxicity to the developing brain: the clinical relevance
    • Davidson A.J. Anesthesia and neurotoxicity to the developing brain: the clinical relevance. Paediatr Anaesth 2011, 21:716-721.
    • (2011) Paediatr Anaesth , vol.21 , pp. 716-721
    • Davidson, A.J.1
  • 10
    • 77957836723 scopus 로고    scopus 로고
    • Anaesthetic-related neuroprotection: intravenous or inhalational agents?
    • Schifilliti D., Grasso G., Conti A., Fodale V. Anaesthetic-related neuroprotection: intravenous or inhalational agents?. CNS Drugs 2010, 24:893-907.
    • (2010) CNS Drugs , vol.24 , pp. 893-907
    • Schifilliti, D.1    Grasso, G.2    Conti, A.3    Fodale, V.4
  • 11
    • 65349138880 scopus 로고    scopus 로고
    • Update on neonatal anesthetic neurotoxicity: insight into molecular mechanisms and relevance to humans
    • Patel P., Sun L. Update on neonatal anesthetic neurotoxicity: insight into molecular mechanisms and relevance to humans. Anesthesiology 2009, 110:703-708.
    • (2009) Anesthesiology , vol.110 , pp. 703-708
    • Patel, P.1    Sun, L.2
  • 12
    • 77449084843 scopus 로고    scopus 로고
    • Use of analgesic and sedative drugs in the NICU: integrating clinical trials and laboratory data
    • Durrmeyer X., Vutskits L., Anand K.J., Rimensberger P.C. Use of analgesic and sedative drugs in the NICU: integrating clinical trials and laboratory data. Pediatr Res 2010, 67:117-127.
    • (2010) Pediatr Res , vol.67 , pp. 117-127
    • Durrmeyer, X.1    Vutskits, L.2    Anand, K.J.3    Rimensberger, P.C.4
  • 13
    • 77955307257 scopus 로고    scopus 로고
    • Cerebral processing of pain in school-aged children with neonatal nociceptive input: an exploratory fMRI study
    • Hohmeister J., Kroll A., Wollgarten-Hadamek I., et al. Cerebral processing of pain in school-aged children with neonatal nociceptive input: an exploratory fMRI study. Pain 2010, 150:257-267.
    • (2010) Pain , vol.150 , pp. 257-267
    • Hohmeister, J.1    Kroll, A.2    Wollgarten-Hadamek, I.3
  • 14
    • 58149171906 scopus 로고    scopus 로고
    • Long-term impact of neonatal intensive care and surgery on somatosensory perception in children born extremely preterm
    • Walker S.M., Franck L.S., Fitzgerald M., Myles J., Stocks J., Marlow N. Long-term impact of neonatal intensive care and surgery on somatosensory perception in children born extremely preterm. Pain 2009, 141:79-87.
    • (2009) Pain , vol.141 , pp. 79-87
    • Walker, S.M.1    Franck, L.S.2    Fitzgerald, M.3    Myles, J.4    Stocks, J.5    Marlow, N.6
  • 15
    • 68249144472 scopus 로고    scopus 로고
    • Morphine glucuronidation in preterm neonates, infants and children younger than 3 years
    • Knibbe C.A., Krekels E.H., van den Anker J.N., et al. Morphine glucuronidation in preterm neonates, infants and children younger than 3 years. Clin Pharmacokinet 2009, 48:371-385.
    • (2009) Clin Pharmacokinet , vol.48 , pp. 371-385
    • Knibbe, C.A.1    Krekels, E.H.2    van den Anker, J.N.3
  • 16
    • 78649928757 scopus 로고    scopus 로고
    • Predictive performance of a recently developed population pharmacokinetic model for morphine and its metabolites in new datasets of (preterm) neonates, infants and children
    • Krekels E.H., DeJongh J., van Lingen R.A., et al. Predictive performance of a recently developed population pharmacokinetic model for morphine and its metabolites in new datasets of (preterm) neonates, infants and children. Clin Pharmacokinet 2011, 50:51-63.
    • (2011) Clin Pharmacokinet , vol.50 , pp. 51-63
    • Krekels, E.H.1    DeJongh, J.2    van Lingen, R.A.3
  • 17
    • 79956073366 scopus 로고    scopus 로고
    • Long-term effects of routine morphine infusion in mechanically ventilated neonates on children's functioning: five-year follow-up of a randomized controlled trial
    • de Graaf J., van Lingen R.A., Simons S.H., et al. Long-term effects of routine morphine infusion in mechanically ventilated neonates on children's functioning: five-year follow-up of a randomized controlled trial. Pain 2011, 152:1391-1397.
    • (2011) Pain , vol.152 , pp. 1391-1397
    • de Graaf, J.1    van Lingen, R.A.2    Simons, S.H.3
  • 18
    • 82655178419 scopus 로고    scopus 로고
    • A pilot study of preemptive morphine analgesia in preterm neonates: effects on head circumference, social behavior, and response latencies in early childhood
    • Ferguson S.A., Ward W.L., Paule M.G., Hall R.W., Anand K.J. A pilot study of preemptive morphine analgesia in preterm neonates: effects on head circumference, social behavior, and response latencies in early childhood. Neurotoxicol Teratol 2012, 34:47-55.
    • (2012) Neurotoxicol Teratol , vol.34 , pp. 47-55
    • Ferguson, S.A.1    Ward, W.L.2    Paule, M.G.3    Hall, R.W.4    Anand, K.J.5
  • 19
  • 21
    • 77949800201 scopus 로고    scopus 로고
    • Remifentanil for endotracheal intubation in neonates: a randomised controlled trial
    • Choong K., AlFaleh K., Doucette J., et al. Remifentanil for endotracheal intubation in neonates: a randomised controlled trial. Arch Dis Child Fetal Neonatal Ed 2010, 95:F80-F84.
    • (2010) Arch Dis Child Fetal Neonatal Ed , vol.95
    • Choong, K.1    AlFaleh, K.2    Doucette, J.3
  • 22
    • 0141677962 scopus 로고    scopus 로고
    • Efficacy and safety of continuous intravenous infusion of remifentanil in preterm infants undergoing laser therapy in retinopathy of prematurity: clinical experience
    • Sammartino M., Bocci M.G., Ferro G., et al. Efficacy and safety of continuous intravenous infusion of remifentanil in preterm infants undergoing laser therapy in retinopathy of prematurity: clinical experience. Paediatr Anaesth 2003, 13:596-602.
    • (2003) Paediatr Anaesth , vol.13 , pp. 596-602
    • Sammartino, M.1    Bocci, M.G.2    Ferro, G.3
  • 23
    • 47349089163 scopus 로고    scopus 로고
    • Remifentanil for percutaneous intravenous central catheter placement in preterm infant: a randomized controlled trial
    • Lago P., Tiozzo C., Boccuzzo G., Allegro A., Zachello F. Remifentanil for percutaneous intravenous central catheter placement in preterm infant: a randomized controlled trial. Paediatr Anaesth 2008, 18:736-744.
    • (2008) Paediatr Anaesth , vol.18 , pp. 736-744
    • Lago, P.1    Tiozzo, C.2    Boccuzzo, G.3    Allegro, A.4    Zachello, F.5
  • 25
    • 41949118720 scopus 로고    scopus 로고
    • Covariates of tramadol disposition in the first months of life
    • Allegaert K., van den Anker J.N., de Hoon J.N., et al. Covariates of tramadol disposition in the first months of life. Br J Anaesth 2008, 100:525-532.
    • (2008) Br J Anaesth , vol.100 , pp. 525-532
    • Allegaert, K.1    van den Anker, J.N.2    de Hoon, J.N.3
  • 26
    • 79951611054 scopus 로고    scopus 로고
    • Developmental pharmacology of tramadol during infancy: ontogeny, pharmacogenetics and elimination clearance
    • Allegaert K., Rochette A., Veyckemans F. Developmental pharmacology of tramadol during infancy: ontogeny, pharmacogenetics and elimination clearance. Paediatr Anaesth 2011, 21:266-273.
    • (2011) Paediatr Anaesth , vol.21 , pp. 266-273
    • Allegaert, K.1    Rochette, A.2    Veyckemans, F.3
  • 29
    • 82655181933 scopus 로고    scopus 로고
    • Controversial issues in pediatric regional anesthesia
    • Mossetti V., Ivani G. Controversial issues in pediatric regional anesthesia. Paediatr Anaesth 2012, 22:109-114.
    • (2012) Paediatr Anaesth , vol.22 , pp. 109-114
    • Mossetti, V.1    Ivani, G.2
  • 30
    • 84867979291 scopus 로고    scopus 로고
    • Effect of wound infiltration with bupivacaine on postoperative analgesia in neonates and infants undergoing major abdominal surgery: a pilot randomized controlled trial
    • Leelanukrom R., Suraseranivongse S., Boonrukwanich V., Wechwinij S. Effect of wound infiltration with bupivacaine on postoperative analgesia in neonates and infants undergoing major abdominal surgery: a pilot randomized controlled trial. J Anesth 2012, 26:541-544.
    • (2012) J Anesth , vol.26 , pp. 541-544
    • Leelanukrom, R.1    Suraseranivongse, S.2    Boonrukwanich, V.3    Wechwinij, S.4
  • 31
  • 32
    • 80052394608 scopus 로고    scopus 로고
    • The transversusabdominis plane (TAP) block in neonates and infants - results of an audit
    • Jacobs A., Bergmans E., Arul G.S., Thies K.C. The transversusabdominis plane (TAP) block in neonates and infants - results of an audit. Paediatr Anaesth 2011, 21:1078-1080.
    • (2011) Paediatr Anaesth , vol.21 , pp. 1078-1080
    • Jacobs, A.1    Bergmans, E.2    Arul, G.S.3    Thies, K.C.4
  • 33
    • 65349090666 scopus 로고    scopus 로고
    • Postoperative analgesia in neonates after major abdominal surgery: 'TAP' our way to success!
    • Bielsky A., Efrat R., Suresh S. Postoperative analgesia in neonates after major abdominal surgery: 'TAP' our way to success!. Paediatr Anaesth 2009, 19:541-542.
    • (2009) Paediatr Anaesth , vol.19 , pp. 541-542
    • Bielsky, A.1    Efrat, R.2    Suresh, S.3
  • 34
    • 80055086924 scopus 로고    scopus 로고
    • Local anaesthetic eye drops for prevention of pain in preterm infants undergoing screening for retinopathy of prematurity
    • Dempsey E., McCreery K. Local anaesthetic eye drops for prevention of pain in preterm infants undergoing screening for retinopathy of prematurity. Cochrane Database Syst Rev 2011, CD007645.
    • (2011) Cochrane Database Syst Rev
    • Dempsey, E.1    McCreery, K.2
  • 35
    • 84856216551 scopus 로고    scopus 로고
    • Options for procedural pain in newborn infants
    • Meek J. Options for procedural pain in newborn infants. Arch Dis Child Educ Pract Ed 2012, 97:23-28.
    • (2012) Arch Dis Child Educ Pract Ed , vol.97 , pp. 23-28
    • Meek, J.1
  • 36
    • 77958012855 scopus 로고    scopus 로고
    • Oral sucrose as an analgesic drug for procedural pain in newborn infants: a randomised controlled trial
    • Slater R., Cornelissen L., Fabrizi L., et al. Oral sucrose as an analgesic drug for procedural pain in newborn infants: a randomised controlled trial. Lancet 2010, 376(9748):1225-1232.
    • (2010) Lancet , vol.376 , Issue.9748 , pp. 1225-1232
    • Slater, R.1    Cornelissen, L.2    Fabrizi, L.3
  • 37
    • 34347330732 scopus 로고    scopus 로고
    • Shouldn't we reconsider procedural techniques to prevent neonatal pain?
    • Allegaert K., Tibboel D. Shouldn't we reconsider procedural techniques to prevent neonatal pain?. Eur J Pain 2007, 11:910-912.
    • (2007) Eur J Pain , vol.11 , pp. 910-912
    • Allegaert, K.1    Tibboel, D.2
  • 38
    • 79957547727 scopus 로고    scopus 로고
    • Open transumbilical pyloromyotomy: is it more painful than the laparoscopic approach?
    • Lemoine C., Paris C., Morris M., Vali K., Beaunoyer M., Aspirot A. Open transumbilical pyloromyotomy: is it more painful than the laparoscopic approach?. J Pediatr Surg 2011, 46:870-873.
    • (2011) J Pediatr Surg , vol.46 , pp. 870-873
    • Lemoine, C.1    Paris, C.2    Morris, M.3    Vali, K.4    Beaunoyer, M.5    Aspirot, A.6
  • 39
    • 79959378350 scopus 로고    scopus 로고
    • Does minimal access major surgery in the newborn hurt less? An evaluation of cumulative opioid doses
    • Ceelie I., van Dijk M., Bax N.M., de Wildt S.N., Tibboel D. Does minimal access major surgery in the newborn hurt less? An evaluation of cumulative opioid doses. Eur J Pain 2011, 15:615-620.
    • (2011) Eur J Pain , vol.15 , pp. 615-620
    • Ceelie, I.1    van Dijk, M.2    Bax, N.M.3    de Wildt, S.N.4    Tibboel, D.5
  • 40
    • 79956308263 scopus 로고    scopus 로고
    • The pharmacokinetics of intravenous paracetamol in neonates: size matters most
    • Allegaert K., Palmer G.M., Anderson B.J. The pharmacokinetics of intravenous paracetamol in neonates: size matters most. Arch Dis Child 2011, 96:575-580.
    • (2011) Arch Dis Child , vol.96 , pp. 575-580
    • Allegaert, K.1    Palmer, G.M.2    Anderson, B.J.3
  • 41
    • 41749124574 scopus 로고    scopus 로고
    • Hepatic tolerance of repeated intravenous paracetamol administration in neonates
    • Allegaert K., Rayyan M., de Rijdt T., van Beek F., Naulaers G. Hepatic tolerance of repeated intravenous paracetamol administration in neonates. Paediatr Anaesth 2008, 18:388-392.
    • (2008) Paediatr Anaesth , vol.18 , pp. 388-392
    • Allegaert, K.1    Rayyan, M.2    de Rijdt, T.3    van Beek, F.4    Naulaers, G.5
  • 42
    • 77956134662 scopus 로고    scopus 로고
    • Haemodynamics of intravenous paracetamol in neonates
    • Allegaert K., Naulaers G. Haemodynamics of intravenous paracetamol in neonates. Eur J Clin Pharmacol 2010, 66:855-858.
    • (2010) Eur J Clin Pharmacol , vol.66 , pp. 855-858
    • Allegaert, K.1    Naulaers, G.2
  • 43
    • 79951678087 scopus 로고    scopus 로고
    • Does intravenous paracetamol administration affect body temperature in neonates?
    • Hopchet L., Kulo A., Rayyan M., et al. Does intravenous paracetamol administration affect body temperature in neonates?. Arch Dis Child 2011, 96:301-304.
    • (2011) Arch Dis Child , vol.96 , pp. 301-304
    • Hopchet, L.1    Kulo, A.2    Rayyan, M.3
  • 44
    • 79956316377 scopus 로고    scopus 로고
    • Pain relief in neonates: when to use intravenous paracetamol?
    • Van den Anker J.N., Tibboel D. Pain relief in neonates: when to use intravenous paracetamol?. Arch Dis Child 2011, 96:573-574.
    • (2011) Arch Dis Child , vol.96 , pp. 573-574
    • Van den Anker, J.N.1    Tibboel, D.2
  • 45
    • 52049087357 scopus 로고    scopus 로고
    • Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in children aged 6-7 years: analysis from Phase Three of the ISAAC programme
    • Beasley R., Clayton T., Crane J., et al. Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in children aged 6-7 years: analysis from Phase Three of the ISAAC programme. Lancet 2008, 372(9643):1039-1048.
    • (2008) Lancet , vol.372 , Issue.9643 , pp. 1039-1048
    • Beasley, R.1    Clayton, T.2    Crane, J.3
  • 46
    • 84856526164 scopus 로고    scopus 로고
    • Intravenous acetaminophen in the United States: iatrogenic dosing errors
    • Dart R.C., Rumack B.H. Intravenous acetaminophen in the United States: iatrogenic dosing errors. Pediatrics 2012, 129:349-353.
    • (2012) Pediatrics , vol.129 , pp. 349-353
    • Dart, R.C.1    Rumack, B.H.2
  • 47
    • 84860598273 scopus 로고    scopus 로고
    • Level of NICU quality of developmental care and neurobehavioral performance in very preterm infants
    • Montirosso R., Del Prete A., Bellu R., et al. Level of NICU quality of developmental care and neurobehavioral performance in very preterm infants. Pediatrics 2012, 129:e1129-e1137.
    • (2012) Pediatrics , vol.129
    • Montirosso, R.1    Del Prete, A.2    Bellu, R.3
  • 48
    • 84863066896 scopus 로고    scopus 로고
    • Neonatal drug withdrawal
    • Committee on drugs; Committee on fetus and newborn; American Academy of Pediatrics
    • Hudak M.L., Tan R.C. Neonatal drug withdrawal. Pediatrics 2012, 129:e540-e560. Committee on drugs; Committee on fetus and newborn; American Academy of Pediatrics.
    • (2012) Pediatrics , vol.129
    • Hudak, M.L.1    Tan, R.C.2
  • 49
    • 84055191637 scopus 로고    scopus 로고
    • Suspected opioid-induced hyperalgesia in an infant
    • Hallett B.R., Chalkiadis G.A. Suspected opioid-induced hyperalgesia in an infant. Br J Anaesth 2012, 108:116-118.
    • (2012) Br J Anaesth , vol.108 , pp. 116-118
    • Hallett, B.R.1    Chalkiadis, G.A.2
  • 50
    • 77956940764 scopus 로고    scopus 로고
    • Propofol overdose in a preterm baby: may propofol infusion syndrome arise in two hours?
    • Sammartino M., Garra R., Sbaraglia F., Papacci P. Propofol overdose in a preterm baby: may propofol infusion syndrome arise in two hours?. Paediatr Anaesth 2010, 20:973-974.
    • (2010) Paediatr Anaesth , vol.20 , pp. 973-974
    • Sammartino, M.1    Garra, R.2    Sbaraglia, F.3    Papacci, P.4
  • 52
    • 84857132737 scopus 로고    scopus 로고
    • Electrophysiological measurements and analysis of nociception in human infants
    • Fabrizi L., Worley A., Patten D., et al. Electrophysiological measurements and analysis of nociception in human infants. J Vis Exp 2011, 58:3118.
    • (2011) J Vis Exp , vol.58 , pp. 3118
    • Fabrizi, L.1    Worley, A.2    Patten, D.3
  • 53
    • 0033842775 scopus 로고    scopus 로고
    • Skin conductance and the stress response from heel stick in preterm infants
    • Storm H. Skin conductance and the stress response from heel stick in preterm infants. Arch Dis Child Fetal Neonatal Ed 2000, 83:F143-F147.
    • (2000) Arch Dis Child Fetal Neonatal Ed , vol.83
    • Storm, H.1
  • 54
    • 84857984749 scopus 로고    scopus 로고
    • Skin conductance peaks could result from changes in vital parameters unrelated to pain
    • Valkenburg A.J., Niehof S.P., van Dijk M., Verhaar E.J., Tibboel D. Skin conductance peaks could result from changes in vital parameters unrelated to pain. Pediatr Res 2012, 71(4 Pt 1):375-379.
    • (2012) Pediatr Res , vol.71 , Issue.4 PT 1 , pp. 375-379
    • Valkenburg, A.J.1    Niehof, S.P.2    van Dijk, M.3    Verhaar, E.J.4    Tibboel, D.5
  • 55
    • 79955596580 scopus 로고    scopus 로고
    • The role of population PK-PD modelling in paediatric clinical research
    • de Cock R.F., Piana C., Krekels E.H., et al. The role of population PK-PD modelling in paediatric clinical research. Eur J Clin Pharmacol 2011, 67(Suppl. 1):5-16.
    • (2011) Eur J Clin Pharmacol , vol.67 , Issue.SUPPL 1 , pp. 5-16
    • de Cock, R.F.1    Piana, C.2    Krekels, E.H.3


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