White matter organization and neurocognitive performance variability in schizophrenia

Schizophrenia Research

Volumn 143, Issue 1, 2013, Pages 172-178

  Roalf, David R ^a   Ruparel, Kosha ^a   Verma, Ragini ^a   Elliott, Mark A ^a   Gur, Raquel E ^a   Gur, Ruben C ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cognition; Diffusion tensor imaging; Intraindividual variability; White matter

Indexed keywords

ACCURACY; ADULT; ARTICLE; CLINICAL ARTICLE; COGNITION; COMPUTERIZED NEUROCOGNITIVE BATTERY; CONTROLLED STUDY; CORPUS CALLOSUM; DIFFUSION TENSOR IMAGING; FEMALE; FRACTIONAL ANISOTROPY; HUMAN; IMAGE PROCESSING; MALE; PRIORITY JOURNAL; PSYCHOLOGIC TEST; SCHIZOPHRENIA; TASK PERFORMANCE; TRACT BASED SPATIAL STATISTICS; WHITE MATTER;

ADULT; ANISOTROPY; BRAIN; BRAIN MAPPING; COGNITION DISORDERS; DIFFUSION TENSOR IMAGING; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; NERVE FIBERS, MYELINATED; NEUROPSYCHOLOGICAL TESTS; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA; YOUNG ADULT;

EID: 84871933670     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2012.10.014     Document Type: Article

References (68)

1. Andreasen N.C. The Scale for the Assessment of Negative Symptoms (SANS) 1984, University of Iowa, Iowa City, Iowa.
2. Andreasen N.C. The Scale for the Assessment of Positive Symptoms (SAPS) 1984, University of Iowa, Iowa City, Iowa.
3. Bediou B., Asri F., Brunelin J., Krolak-Salmon P., D'Amato T., Saoud M., Tazi I. Emotion recognition and genetic vulnerability to schizophrenia. Br. J. Psychiatry 2007, 191:126-130.
4. Bush G., Vogt B.A., Holmes J., Dale A.M., Greve D., Jenike M.A., Rosen B.R. Dorsal anterior cingulate cortex: a role in reward-based decision making. Proc. Natl. Acad. Sci. U. S. A. 2002, 99(1):523-528.
5. Carroll C.A., O'Donnell B.F., Shekhar A., Hetrick W.P. Timing dysfunctions in schizophrenia span from millisecond to several-second durations. Brain Cogn. 2009, 70(2):181-190.
6. Carter C.S., MacDonald A.W., Ross L.L., Stenger V.A. Anterior cingulate cortex activity and impaired self-monitoring of performance in patients with schizophrenia: an event-related fMRI study. Am. J. Psychiatry 2001, 158(9):1423-1428.
7. Chang L., Friedman J., Ernst T., Zhong K., Tsopelas N.D., Davis K. Brain metabolite abnormalities in the white matter of elderly schizophrenic subjects: implication for glial dysfunction. Biol. Psychiatry 2007, 62(12):1396-1404.
8. Cho R.Y., Konecky R.O., Carter C.S. Impairments in frontal cortical gamma synchrony and cognitive control in schizophrenia. Proc. Natl. Acad. Sci. U. S. A. 2006, 103(52):19878-19883.
9. Clark K.A., Nuechterlein K.H., Asarnow R.F., Hamilton L.S., Phillips O.R., Hageman N.S., Woods R.P., Alger J.R., Toga A.W., Narr K.L. Mean diffusivity and fractional anisotropy as indicators of disease and genetic liability to schizophrenia. J. Psychiatr. Res. 2011, 45(7):980-988.
10. Cole V.T., Weinberger D.R., Dickinson D. Intra-individual variability across neuropsychological tasks in schizophrenia: a comparison of patients, their siblings, and healthy controls. Schizophr. Res. 2011, 129(1):91-93.
11. Croxson P.L., Johansen-Berg H., Behrens T.E., Robson M.D., Pinsk M.A., Gross C.G., Richter W., Richter M.C., Kastner S., Rushworth M.F. Quantitative investigation of connections of the prefrontal cortex in the human and macaque using probabilistic diffusion tractography. J. Neurosci. 2005, 25(39):8854-8866.
12. Davatzikos C., Shen D., Gur R.C., Wu X., Liu D., Fan Y., Hughett P., Turetsky B.I., Gur R.E. Whole-brain morphometric study of schizophrenia revealing a spatially complex set of focal abnormalities. Arch. Gen. Psychiatry 2005, 62(11):1218-1227.
13. Davis K.L., Stewart D.G., Friedman J.I., Buchsbaum M., Harvey P.D., Hof P.R., Buxbaum J., Haroutunian V. White matter changes in schizophrenia: evidence for myelin-related dysfunction. Arch. Gen. Psychiatry 2003, 60(5):443-456.
14. Di Rosa E., Crow T.J., Chance S.A. Axon bundle spacing in the anterior cingulate cortex of the human brain. J. Clin. Neurosci. 2008, 15(12):1389-1392.
15. Duffau H., Gatignol P., Mandonnet E., Peruzzi P., Tzourio-Mazoyer N., Capelle L. New insights into the anatomo-functional connectivity of the semantic system: a study using cortico-subcortical electrostimulations. Brain 2005, 128(Pt 4):797-810.
16. Eack S.M., Mermon D.E., Montrose D.M., Miewald J., Gur R.E., Gur R.C., Sweeney J.A., Keshavan M.S. Social cognition deficits among individuals at familial high risk for schizophrenia. Schizophr. Bull. 2010, 36(6):1081-1088.
17. First M.B., Spitzer R.L., Gibbon M., Williams J.B.W. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition (SCID-I/P). Biometrics Research 2002, New York State Psychiatric Institute, New York.
18. Forstmann B.U., Jahfari S., Scholte H.S., Wolfensteller U., van den Wildenberg W.P., Ridderinkhof K.R. Function and structure of the right inferior frontal cortex predict individual differences in response inhibition: a model-based approach. J. Neurosci. 2008, 28(39):9790-9796.
19. Goldman-Rakic P.S., Selemon L.D., Schwartz M.L. Dual pathways connecting the dorsolateral prefrontal cortex with the hippocampal formation and parahippocampal cortex in the rhesus monkey. Neuroscience 1984, 12(3):719-743.
20. Gur R.E., Turetsky B.I., Cowell P.E., Finkelman C., Maany V., Grossman R.I., Arnold S.E., Bilker W.B., Gur R.C. Temporolimbic volume reductions in schizophrenia. Arch. Gen. Psychiatry 2000, 57(8):769-775.
21. Gur R.C., Ragland J.D., Moberg P.J., Bilker W.B., Kohler C., Siegel S.J., Gur R.E. Computerized neurocognitive scanning: II. The profile of schizophrenia. Neuropsychopharmacology 2001, 25(5):777-788.
22. Gur R.C., Ragland J.D., Moberg P.J., Turner T.H., Bilker W.B., Kohler C., Siegel S.J., Gur R.E. Computerized neurocognitive scanning: I. Methodology and validation in healthy people. Neuropsychopharmacology 2001, 25(5):766-776.
23. Gur R.C., Richard J., Hughett P., Calkins M.E., Macy L., Bilker W.B., Brensinger C., Gur R.E. A cognitive neuroscience-based computerized battery for efficient measurement of individual differences: standardization and initial construct validation. J. Neurosci. Methods 2010, 187(2):254-262.
24. Holtzer R., Verghese J., Wang C., Hall C.B., Lipton R.B. Within-person across-neuropsychological test variability and incident dementia. JAMA 2008, 300(7):823-830.
25. Ikuta T., Szeszko P.R., Gruner P., Derosse P., Gallego J., Malhotra A.K. Abnormal anterior cingulate cortex activity predicts functional disability in schizophrenia. Schizophr. Res. 2012, 137(1-3):267-268.
26. Irani F., Seligman S., Kamath V., Kohler C., Gur R.C. A meta-analysis of emotion perception and functional outcomes in schizophrenia. Schizophr. Res. 2012, 137(1-3):203-211.
27. Jacobson S., Kelleher I., Harley M., Murtagh A., Clarke M., Blanchard M., Connolly C., O'Hanlon E., Garavan H., Cannon M. Structural and functional brain correlates of subclinical psychotic symptoms in 11-13year old schoolchildren. NeuroImage 2010, 49(2):1875-1885.
28. Jenkinson M., Bannister P., Brady M., Smith S. Improved optimization for the robust and accurate linear registration and motion correction of brain images. NeuroImage 2002, 17(2):825-841.
29. Kaiser S., Roth A., Rentrop M., Friederich H.C., Bender S., Weisbrod M. Intra-individual reaction time variability in schizophrenia, depression and borderline personality disorder. Brain Cogn. 2008, 66(1):73-82.
30. Klein C., Wendling K., Huettner P., Ruder H., Peper M. Intra-subject variability in attention-deficit hyperactivity disorder. Biol. Psychiatry 2006, 60(10):1088-1097.
31. Koch K., Wagner G., Dahnke R., Schachtzabel C., Schultz C., Roebel M., Gullmar D., Reichenbach J.R., Sauer H., Schlosser R.G. Disrupted white matter integrity of corticopontine-cerebellar circuitry in schizophrenia. Eur. Arch. Psychiatry Clin. Neurosci. 2010, 260(5):419-426.
32. Kubicki M., Westin C.F., Maier S.E., Frumin M., Nestor P.G., Salisbury D.F., Kikinis R., Jolesz F.A., McCarley R.W., Shenton M.E. Uncinate fasciculus findings in schizophrenia: a magnetic resonance diffusion tensor imaging study. Am. J. Psychiatry 2002, 159(5):813-820.
33. Kyriakopoulos M., Frangou S. Recent diffusion tensor imaging findings in early stages of schizophrenia. Curr. Opin. Psychiatry 2009, 22(2):168-176.
34. Kyriakopoulos M., Bargiotas T., Barker G.J., Frangou S. Diffusion tensor imaging in schizophrenia. Eur. Psychiatry 2008, 23(4):255-273.
35. Lee J., Gosselin F., Wynn J.K., Green M.F. How do schizophrenia patients use visual information to decode facial emotion?. Schizophr. Bull. 2011, 37(5):1001-1008.
36. Leth-Steensen C., Elbaz Z.K., Douglas V.I. Mean response times, variability, and skew in the responding of ADHD children: a response time distributional approach. Acta Psychol. (Amst) 2000, 104(2):167-190.
37. MacDonald S.W., Li S.C., Backman L. Neural underpinnings of within-person variability in cognitive functioning. Psychol. Aging 2009, 24(4):792-808.
38. Manoach D.S., Ketwaroo G.A., Polli F.E., Thakkar K.N., Barton J.J., Goff D.C., Fischl B., Vangel M., Tuch D.S. Reduced microstructural integrity of the white matter underlying anterior cingulate cortex is associated with increased saccadic latency in schizophrenia. NeuroImage 2007, 37(2):599-610.
39. Martino J., Vergani F., Robles S.G., Duffau H. New insights into the anatomic dissection of the temporal stem with special emphasis on the inferior fronto-occipital fasciculus: implications in surgical approach to left mesiotemporal and temporoinsular structures. Neurosurgery 2010, 66(3 Suppl. Operative):4-12.
40. Mitelman S.A., Newmark R.E., Torosjan Y., Chu K.W., Brickman A.M., Haznedar M.M., Hazlett E.A., Tang C.Y., Shihabuddin L., Buchsbaum M.S. White matter fractional anisotropy and outcome in schizophrenia. Schizophr. Res. 2006, 87(1-3):138-159.
41. Mori S., Wakana S., van Zijl P.C.M., Nagae-Poetscher L.M. MRI Atlas of Human White Matter 2005, Elsevier, Amsterdam, The Netherlands. 1st ed.
42. Morris R.W., Weickert C.S., Loughland C.M. Emotional face processing in schizophrenia. Curr. Opin. Psychiatry 2009, 22(2):140-146.
43. Mukherjee P., Chung S.W., Berman J.I., Hess C.P., Henry R.G. Diffusion tensor MR imaging and fiber tractography: technical considerations. AJNR Am. J. Neuroradiol. 2008, 29(5):843-852.
44. Nestor P.G., Kubicki M., Gurrera R.J., Niznikiewicz M., Frumin M., McCarley R.W., Shenton M.E. Neuropsychological correlates of diffusion tensor imaging in schizophrenia. Neuropsychology 2004, 18(4):629-637.
45. Nestor P.G., Kubicki M., Spencer K.M., Niznikiewicz M., McCarley R.W., Shenton M.E. Attentional networks and cingulum bundle in chronic schizophrenia. Schizophr. Res. 2007, 90(1-3):308-315.
46. Nestor P.G., Kubicki M., Niznikiewicz M., Gurrera R.J., McCarley R.W., Shenton M.E. Neuropsychological disturbance in schizophrenia: a diffusion tensor imaging study. Neuropsychology 2008, 22(2):246-254.
47. Overall J.E., Gorham D.R. The brief psychiatric rating scale. Psychol. Rep. 1962, 10:799-812.
48. Perez-Iglesias R., Tordesillas-Gutierrez D., McGuire P.K., Barker G.J., Roiz-Santianez R., Mata I., de Lucas E.M., Rodriguez-Sanchez J.M., Ayesa-Arriola R., Vazquez-Barquero J.L., Crespo-Facorro B. White matter integrity and cognitive impairment in first-episode psychosis. Am. J. Psychiatry 2010, 167(4):451-458.
49. Philippi C.L., Mehta S., Grabowski T., Adolphs R., Rudrauf D. Damage to association fiber tracts impairs recognition of the facial expression of emotion. J. Neurosci. 2009, 29(48):15089-15099.
50. Phillips O.R., Nuechterlein K.H., Clark K.A., Hamilton L.S., Asarnow R.F., Hageman N.S., Toga A.W., Narr K.L. Fiber tractography reveals disruption of temporal lobe white matter tracts in schizophrenia. Schizophr. Res. 2009, 107(1):30-38.
51. Reichenberg A., Weiser M., Rapp M.A., Rabinowitz J., Caspi A., Schmeidler J., Knobler H.Y., Lubin G., Nahon D., Harvey P.D., Davidson M. Premorbid intra-individual variability in intellectual performance and risk for schizophrenia: a population-based study. Schizophr. Res. 2006, 85(1-3):49-57.
52. Rentrop M., Rodewald K., Roth A., Simon J., Walther S., Fiedler P., Weisbrod M., Kaiser S. Intra-individual variability in high-functioning patients with schizophrenia. Psychiatry Res. 2010, 178(1):27-32.
53. Roalf D.R., Gur R.C., Almasy L., Richard J., Gallagher R.S., Prasad K., Wood J., Pogue-Geile M.F., Nimgaonkar V.L., Gur R.E. Neurocognitive performance stability in a muliplex multigenerational study of schizophrenia. Schizophr. Bull. 2012, Electronic publication ahead of print August 27, 2012: PMID 22927671.
54. Saykin A.J., Shtasel D.L., Gur R.E., Kester D.B., Mozley L.H., Stafiniak P., Gur R.C. Neuropsychological deficits in neuroleptic naive patients with first-episode schizophrenia. Arch. Gen. Psychiatry 1994, 51(2):124-131.
55. Segal D., Koschnick J.R., Slegers L.H., Hof P.R. Oligodendrocyte pathophysiology: a new view of schizophrenia. Int. J. Neuropsychopharmacol. 2007, 10(4):503-511.
56. Smith S.M. Fast robust automated brain extraction. Hum. Brain Mapp. 2002, 17(3):143-155.
57. Smith S.M., Jenkinson M., Johansen-Berg H., Rueckert D., Nichols T.E., Mackay C.E., Watkins K.E., Ciccarelli O., Cader M.Z., Matthews P.M., Behrens T.E. Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. NeuroImage 2006, 31(4):1487-1505.
58. Smith S.M., Johansen-Berg H., Jenkinson M., Rueckert D., Nichols T.E., Miller K.L., Robson M.D., Jones D.K., Klein J.C., Bartsch A.J., Behrens T.E. Acquisition and voxelwise analysis of multi-subject diffusion data with tract-based spatial statistics. Nat. Protoc. 2007, 2(3):499-503.
59. Snitz B.E., Macdonald A.W., Carter C.S. Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: a meta-analytic review of putative endophenotypes. Schizophr. Bull. 2006, 32(1):179-194.
60. Spoletini I., Cherubini A., Banfi G., Rubino I.A., Peran P., Caltagirone C., Spalletta G. Hippocampi, thalami, and accumbens microstructural damage in schizophrenia: a volumetry, diffusivity, and neuropsychological study. Schizophr. Bull. 2011, 37(1):118-130.
61. Stuss D.T., Murphy K.J., Binns M.A., Alexander M.P. Staying on the job: the frontal lobes control individual performance variability. Brain 2003, 126(Pt 11):2363-2380.
62. Szeszko P.R., Robinson D.G., Ashtari M., Vogel J., Betensky J., Sevy S., Ardekani B.A., Lencz T., Malhotra A.K., McCormack J., Miller R., Lim K.O., Gunduz-Bruce H., Kane J.M., Bilder R.M. Clinical and neuropsychological correlates of white matter abnormalities in recent onset schizophrenia. Neuropsychopharmacology 2008, 33(5):976-984.
63. Takei K., Yamasue H., Abe O., Yamada H., Inoue H., Suga M., Muroi M., Sasaki H., Aoki S., Kasai K. Structural disruption of the dorsal cingulum bundle is associated with impaired Stroop performance in patients with schizophrenia. Schizophr. Res. 2009, 114(1-3):119-127.
64. Thomas C., Moya L., Avidan G., Humphreys K., Jung K.J., Peterson M.A., Behrmann M. Reduction in white matter connectivity, revealed by diffusion tensor imaging, may account for age-related changes in face perception. J. Cogn. Neurosci. 2008, 20(2):268-284.
65. Vinogradov S., Poole J.H., Willis-Shore J., Ober B.A., Shenaut G.K. Slower and more variable reaction times in schizophrenia: what do they signify?. Schizophr. Res. 1998, 32(3):183-190.
66. Wakana S., Caprihan A., Panzenboeck M.M., Fallon J.H., Perry M., Gollub R.L., Hua K., Zhang J., Jiang H., Dubey P., Blitz A., van Zijl P., Mori S. Reproducibility of quantitative tractography methods applied to cerebral white matter. NeuroImage 2007, 36(3):630-644.
67. Walterfang M., McGuire P.K., Yung A.R., Phillips L.J., Velakoulis D., Wood S.J., Suckling J., Bullmore E.T., Brewer W., Soulsby B., Desmond P., McGorry P.D., Pantelis C. White matter volume changes in people who develop psychosis. Br. J. Psychiatry 2008, 193(3):210-215.
68. Wang K., Cheung E.F., Gong Q.Y., Chan R.C. Semantic processing disturbance in patients with schizophrenia: a meta-analysis of the N400 component. PLoS One 2011, 6(10):e25435.