Slower and more variable reaction times in schizophrenia: What do they signify?

Schizophrenia Research

Volumn 32, Issue 3, 1998, Pages 183-190

  Vinogradov, Sophia ^a,b   Poole, John H ^a,b   Willis Shore, Jason ^a,b   Ober, Beth A ^c,d   Shenaut, Gregory K ^c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Intra individual variability in reaction time; Neurocognition; Neuropsychological profile; Reaction time; Schizophrenia

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; FEMALE; HUMAN; MALE; MOTOR COORDINATION; PRIORITY JOURNAL; RESPONSE TIME; SCHIZOPHRENIA; TASK PERFORMANCE;

ADULT; FEMALE; HUMANS; INTELLIGENCE; MALE; REACTION TIME; SCHIZOPHRENIA;

EID: 0032541459     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-9964(98)00043-7     Document Type: Article

References (24)

1. Collins L.F., Long C.J. Visual reaction time and its relationship to neuropsychological test performance. Arch. Clin. Neuropsychology. 11:1996;613-623.
2. Heaton, R., 1981. Manual for the Wisconsin Card Sorting Test. Psychological Assessment Resources, Odessa, FL.
3. Hetherington C.R., Stuss D.D.T., Finlayson M.A. Reaction time and variability five and ten years after traumatic brain injury. Brain Injury. 10:1996;473-486.
4. Jahn T., Rey E.R. Relationship between crossover and modality shift effects in sequential reaction time performance of schizophrenic patients. Eur. Arch. Psychiatr. Clin. Neurosci. 243:1993;199-204.
5. Kaiser H.F. An index of factorial simplicity. Psychometrika. 39:1974;31-36.
6. Kaufman, A.S., 1990. Assessing Adolescent and Adult Intelligence. Allyn & Bacon, Needham Heights, MA.
7. Lieh-Mak F., Lee P.W. Cognitive deficit measures in schizophrenia: factor structure and clinical correlates. Am. J. Psychiatry. 154:1997;39-46.
8. Maier W., Franke P., Kopp B., Hardt J., Hain C., Rist F. Reaction time paradigms in subjects at risk for schizophrenia. Schizophr. Res. 13:1994;35-43.
9. Malloy P., Richardson E. Assesment of frontal lobe functions. J. Neuropsychiatry. 6:1994;399-410.
10. Merriam A.E., Kay S.R., Opler L.A., Kushner S.F.et al. Neurological signs and the positive-negative dimension in schizophrenia. Biol. Psychiatry. 28:1990;181-192.
11. Nuechterlein K.H. Reaction time and attention in schizophrenia: a critical evaluation of the data and theories. Schizophr. Bull. 3:1977;373-428.
12. Ober B., Vinogradov S., Shenaut G. Automatic vs. controlled semantic priming in schizophrenia. Neuropsychology. 11:1997;506-513.
13. Overall J., Gorham D. The Brief Psychiatric Rating Scale. Psychol. Res. 10:1962;799-812.
14. Rodnick E.H., Shakow D. Set in the schizophrenic as measured by a composite reaction time index. Am. J. Psychiatry. 97:1940;214-225.
15. Rosenthal D., Lawlor W.G., Zahn T.P., Shakow D. The relationship of some aspects of mental set to degree of schizophrenic disorganization. J. Personal. 28:1960;26-38.
16. Schatz J. Cognitive processing efficiency in schizophrenia: generalized versus domain specific deficits. Schizophr. Res. 30:1998;41-49.
17. Schreiber H., Stolz-Born G., Heinrich H., Kornhuber H.H.et al. Attention, cognition, and motor perseveration in adolescents at genetic risk for schizophrenia and control subjects. Psychiatr. Res. 44:1992;125-140.
18. Schwartz F., Carr A.C., Munich R.L., Glauber S., Lesser B., Murray J. Reaction time impairment in schizophrenia and affective illness: the role of attention. Biol. Psychiatry. 25:1989;540-548.
19. Segalowitz S.J., Dwyan J., Unsal A. Attentional factors in response time variability after traumatic brain injury: an ERP study. J. Int. Neuropsychol. Soc. 3:1997;95-107.
20. Shakow D. Segmental set: a theory of the formal psychological deficit in schizophrenia. Arch. Gen. Psychiatry. 6:1962;1-17.
21. Shakow D. Psychological deficit in schizophrenia. Behavioral Sci. 8:1963;275-305.
22. Shakow, D., 1977. Schizophrenia: Selected papers. International Universities Press, New York.
23. Shipley W.C. A self-administering scale for measuring intellectual impairment and deterioration. J. Psychol. 9:1940;371-377.
24. Zachary R., Crumpton E., Spiegel D. Estimating WAIS-R IQ from the Shipley Institute of Living Scale. J. Clin. Psychol. 41:1985;532-540.