Solid dispersions for preparation of phototoxic supersaturated solutions for antimicrobial photodynamic therapy (aPDT): Studies on curcumin and curcuminoides L

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 83, Issue 1, 2013, Pages 95-105

  Hegge, Anne Bee ^a   Vukicevic, M ^a   Bruzell, E ^b   Kristensen, S ^a   Tonnesen H H ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b Nordisk Institutt for Odontologiske Materialer   (Norway)

Author keywords

Curcumin; Cyclodextrin; Formulation; Lyophilization; Photodynamic therapy; Supersaturation

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; CURCUMIN; HYDROXYPROPYLMETHYLCELLULOSE; PHOTOSENSITIZING AGENT;

ANTIMICROBIAL PHOTODYNAMIC THERAPY; ANTIMICROBIAL THERAPY; ARTICLE; CONTROLLED STUDY; DISSOLUTION; DRUG SOLUBILITY; FREEZE DRYING; NONHUMAN; PHOTODYNAMIC THERAPY;

ANTI-BACTERIAL AGENTS; BETA-CYCLODEXTRINS; CURCUMIN; DRUG STABILITY; DRUG STORAGE; ESCHERICHIA COLI; EXCIPIENTS; FREEZE DRYING; METHYLCELLULOSE; POROSITY; SOLUBILITY; TIME FACTORS;

EID: 84871923748     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.09.011     Document Type: Article

References (48)

1. T. Haukvik, E. Bruzell, S. Kristensen, and H.H. Tønnesen Photokilling of bacteria by curcumin in different aqueous preparations. Studies on curcumin and curcuminoids XXXVII Pharmazie 64 2009 666 673
2. A.B. Hegge, T.T. Nielsen, K.L. Larsen, E. Bruzell, and H.H. Tønnesen Impact of curcumin supersaturation in antibacterial photodynamic therapy (aPDT)-effect of cyclodextrin type and amount. Studies on curcumin and curcuminoides XLV J. Pharm. Sci. 101 2011 1524 1537
3. T.A. Dahl, W.M. McGowan, M.A. Shand, and V.S. Srinivasan Photokilling of bacteria by the natural dye curcumin Arch. Microbiol. 151 1989 183 185
4. T. Haukvik, E. Bruzell, S. Kristensen, and H.H. Tønnesen Photokilling of bacteria by curcumin in selected polyethylene glycol 400 (PEG 400) preparations. Studies on curcumin and curcuminoids, XLI Pharmazie 65 2010 600 606
5. T. Dai, Y.Y. Huang, and M.R. Hamblin Photodynamic therapy for localized infections-state of the art Photodiag. Photodyn. Ther. 6 2009 170 188
6. M.R. Hamblin, and T. Hasan Photodynamic therapy: a new antimicrobial approach to infectious disease? Photochem. Photobiol. Sci. 3 2004 436 450
7. P.J. Van Duijn, M.J.D. Dautzenberg, and E.A.N. Oostdijk Recent trends in antibiotic resistance in European ICUs Curr. Opin. Crit. Care 17 2011 658 665
8. H. Pabon A synthesis of curcumin and related compounds Recl. Trav. Chim. Pays. Bas. 83 1964 379 386
9. T. Haukvik, Dissertation for the Degree of PhD 2012; curcumin as a photosensitizer in antibacterial photodynamic therapy: Influence of formulation and molecular structure modifications, in: Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway, 2011, pp. 1-81.
10. A.B. Hegge, E. Bruzell, S. Kristensen, H.H. Tønnesen, Photoinactivation of Staphylococcus epidermidis biofilms and suspensions by the hydrophobic photosensitizer curcumin-effect of selected nanocarrier. Studies on curcumin and curcuminoides XLVII, Eur. J. Pharm. Sci. (2012), .
11. B.B. Aggarwal, I.D. Bhatt, H. Ichikawa, K.S. Ahn, G. Sethi, S.K. Sandur, C. Sundaram, N. Seeram, and S. Shishodia Curcumin-biological and medicinal properties P.N. Ravindran, K. Nirmal Babu, K. Sivaraman, Turmeric: The Genius Curcuma 2007 CRC Press New York 297 348
12. H. Hatcher, R. Planalp, J. Cho, F.M. Tortia, and S.V. Torti Curcumin: from ancient medicine to current clinical trials Cell. Mol. Life Sci. 65 2008 1631 1652
13. E.M. Strasser, B. Wessner, N. Manhart, and E. Roth The relationship between the anti-inflammatory effects of curcumin and cellular glutathione content in myelomonocytic cells Biochem. Pharmacol. 70 2005 552 559
14. M.A. Tomren, M. Masson, T. Loftsson, and H.H. Tønnesen Studies on curcumin and curcuminoids XXXI. Symmetric and asymmetric curcuminoids: stability, activity and complexation with cyclodextrin Int. J. Pharm. 338 2007 27 34
15. H.H. Tønnesen, M. Masson, and T. Loftsson Studies of curcumin and curcuminoides. XXVII. Cyclodextrin complexation: solubility, chemical and photochemical stability Int. J. Pharm. 244 2002 127 135
16. B. Tang, L. Ma, H.Y. Wang, and G.Y. Zhang Study on the supramolecular interaction of curcumin and beta-cyclodextrin by spectrophotometry and its analytical application J. Agric. Food Chem. 50 2002 1355 1361
17. K.N. Baglole, P.G. Boland, and B.D. Wagner Fluorescence enhancement of curcumin upon inclusion into parent and modified cyclodextrins J. Photochem. Photobiol. A Chem. 173 2005 230 237
18. H.H. Tønnesen Solubility and stability of curcumin in solutions containing alginate and other viscosity modifying macromolecules: studies of curcumin and curcuminoids, XXX Pharmazie 61 2006 696 700
19. R. Singh, S. Kristensen, and H.H. Tønnesen Influence of cosolvents, ionic strength and the method of sample preparation on the solubilization of curcumin by Pluronics and HP-γ-cyclodextrin Pharmazie 67 2012 131 142
20. L. Zhao, J. Du, Y. Duan, Y. Zang, H. Zhang, C. Yang, F. Cao, and G. Zhai Curcumin loaded mixed micelles composed of Pluronic P123 and F68: preparation, optimization and in vitro characterization Colloids Surf. B Biointerf. 97 2012 101 108
21. A. Sahu, N. Kasoju, P. Goswami, and U. Bora Encapsulation of curcumin in Pluronic block copolymer micelles for drug delivery applications J. Biomater. Appl. 25 2011 619 639
22. M.O. Iwunze Binding and distribution characteristics of curcumin solubilized in CTAB micelle J. Mol. Liq. 111 2004 161 165
23. D. Gopinath, M.R. Ahmed, K. Gomathi, K. Chitra, P.K. Sehgal, and R. Jayakumar Dermal wound healing processes with curcumin incorporated collagen films Biomaterials 25 2004 1911 1917
24. P. Basnet, H. Hussain, I. Tho, and N. Skalko-Basnet Liposomal delivery system enhances anti-inflammatory properties of curcumin J. Pharm. Sci. 101 2012 598 609
25. S. Wan, Y. Sun, and F. Tan Improved bioavailability of poorly water-soluble drug curcumin in cellulose acetate solid dispersion AAPS PharmSciTech 13 2012 159 166
26. S.W. Seo, H.K. Han, M.K. Chun, and H.K. Choi Preparation and pharmacokinetic evaluation of curcumin solid dispersion using Solutol® HS15 as a carrier Int. J. Pharm. 424 2012 18 25
27. A. Paradkar, A.A. Ambike, B.K. Jadhav, and K.R. Mahadik Characterization of curcumin-PVP solid dispersion obtained by spray drying Int. J. Pharm. 271 2004 281 286
28. J. Cui, G.X. Zhai, Y. Zhao, and H.X. Lou Absorption of curcumin microemulsion in vivo Chin. Trad. Herbal Drugs 38 2007 368 372
29. S. Onoue, H. Takahashi, Y. Kawabata, Y. Seto, Y. Hatanaka, B. Timmermann, and S. Shizuo Formulation design and photochemical studies on nanocrystal solid dispersion of curcumin with improved oral bioavailability J. Pharm. Sci. 99 2010 1871 1881
30. M. Dai, X. Zheng, X. Xu, X. Kong, X. Li, G. Guo, F. Luo, X. Zhao, Y. Wei, Z. Qian, Chitosan-alginate sponge: preparation and application in curcumin delivery for dermal wound healing in rat, J. Biomed. Biotechnol., 2009 (ARTNR 595126).
31. Bhawana, R.K. Basniwal, H.S. Buttar, V.K. Jain, and N. Jain Curcumin nanoparticles: preparation, characterization, and antimicrobial study J. Agric. Food Chem. 59 2011 2056 2061
32. S. Bisht, G. Feldmann, S. Soni, R. Ravi, C. Karikar, A. Maitra, and A. Maitra Polymeric nanoparticle-encapsulated curcumin ('nanocurcumin'): a novel strategy for human cancer therapy J. Nanobiotechnol. 5 2007 1 18
33. R.K. Das, N. Kasoju, and U. Bora Encapsulation of curcumin in alginate-chitosan-pluronic composite nanoparticles for delivery to cancer cells Nanomed. Nanotechnol. Biol. Med. 6 2010 153 160
34. P. Sanphui, N.R. Goud, U.B.R. Khandavilli, S. Bhanoth, and A. Nangia New polymorphs of curcumin Chem. Commun. 47 2011 5013 5015
35. B.T. Kurien, A. Singh, H. Matsumoto, and R.H. Scofield Improving the solubility and pharmacological efficacy of curcumin by heat treatment Assay Drug Dev. Technol. 5 2007 567 576
36. E.M. Bruzell, E. Morisbak, and H.H. Tønnesen Studies on curcumin and curcuminoids. XXIX. Photoinduced cytotoxicity of curcumin in selected aqueous preparations Photochem. Photobiol. Sci. 4 2005 523 530
37. C.M. Cassidy, M.M. Tunney, P.A. McCarron, and R.F. Donnelly Drug delivery strategies for photodynamic antimicrobial chemotherapy: from benchtop to clinical practice J. Photochem. Photobiol. B Biol. 95 2009 71 80
38. S. Janssens, and G. Van Den Mooter Review: physical chemistry of solid dispersions J. Pharm. Pharmacol. 61 2009 1571 1586
39. J. Brouwers, M.E. Brewster, and P. Augustijns Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability? J. Pharm. Sci. 98 2009 2549 2572
40. A.B. Hegge, R.B. Schuller, S. Kristiansen, and H.H. Tønnesen In vitro release of curcumin from vehicles containing alginate and cyclodextrin. Studies of curcumin and curcuminoides XXXIII Pharmazie 63 2008 585 592
41. A.B. Hegge, M. Màsson, S. Kristensen, and H.H. Tønnesen Investigation of curcumin-cyclodextrin inclusion complexation in aqueous solutions containing various alcoholic co-solvents and alginates using an UV-VIS titration method Pharmazie 64 2009 382 389
42. A.B. Hegge, T. Andersen, J.E. Melvik, S. Kristensen, and H.H. Tønnesen Evaluation of novel alginate foams as drug delivery systems in antimicrobial photodynamic therapy (aPDT) of infected wounds-an in vitro study. Studies on curcumin and curcuminoides XL J. Pharm. Sci. 99 2010 3499 3513
43. A.B. Hegge, T. Andersen, J.E. Melvik, E. Bruzell, S. Kristensen, and H.H. Tønnesen Formulation and bacterial phototoxicity of curcumin loaded alginate foams for wound treatment applications. Studies on curcumin and curcuminoides XLII J. Pharm. Sci. 100 2010 174 185
44. K.H. Frömming, and J. Szejtli Cyclodextrins in Pharmacy 1994 Kluwer Academic Publishers Dordrecht
45. H.H. Tønnesen, A.B. Hegge, T. Haukvik, and S. Kristensen Antimicrobial Photodynamic Therapy: Minimization of Compound-related Failure by Optimization of the Drug Formulation 2009 Bioprosp Tromsø, Norway
46. J. Liu Physical characterization of pharmaceutical formulations in frozen and freeze-dried solid states: techniques and applications in freeze-drying development Pharm. Dev. Technol. 11 2006 3 28
47. L. Lindfors, S. Forssén, J. Westergren, and U. Olsson Nucleation and crystal growth in supersaturated solutions of a model drug J. Colloid Interf. Sci. 325 2008 404 413
48. M.E. Brewster, and T. Loftsson Cyclodextrins as pharmaceutical solubilizers Adv. Drug Deliv. Rev. 59 2007 645 666