Cycloart-23-ene-3β, 25-diol stimulates GLP-1 (7-36) amide secretion in streptozotocin-nicotinamide induced diabetic Sprague Dawley rats: A mechanistic approach

European Journal of Pharmacology

Volumn 698, Issue 1-3, 2013, Pages 470-479

  Badole, Sachin L ^a   Mahamuni, Sagar P ^a   Bagul, Pranita P ^a   Khose, Rekha D ^a   Joshi, Anuja C ^a   Ghule, Arvindkumar E ^b   Bodhankar, Subhash L ^b   Raut, Chandrashekhar G ^c   Khedkar, Vijay M ^d   Coutinho, Evans C ^d   Wagh, Nilesh K ^e  

^a Affiliated to Savitribai Phule Pune University   (India)

^b BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

^c NATIONAL INSTITUTE OF VIROLOGY   (India)

^d BOMBAY COLLEGE OF PHARMACY   (India)

^e UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

25 diol; Antioxidant markers; Cycloart 23 ene 3 ; GLP 1 (7 36) amide; Insulin; mRNA proglucagon gene expression; Oral glucose tolerance test; Pancreatic cells; Plasma glucose

Indexed keywords

ANTIDIABETIC AGENT; CYCLOART 23 ENE 3BETA,25 DIOL; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 [7-36] AMIDE; GLUCOSE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; GLYCOSYLATED HEMOGLOBIN; INSULIN; MALONALDEHYDE; MESSENGER RNA; SITAGLIPTIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; BINDING AFFINITY; BODY WEIGHT; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; FLUID INTAKE; FOOD INTAKE; GENE EXPRESSION; GLUCAGON LIKE PEPTIDE 1 GENE; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; INSULIN BLOOD LEVEL; LIPID COMPOSITION; MALE; MOLECULAR DOCKING; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN SECRETION; RAT; STREPTOZOCIN DIABETES;

ANIMALS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS, EXPERIMENTAL; DRINKING; GENE EXPRESSION REGULATION; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE TOLERANCE TEST; INSULIN; MALE; MOLECULAR DOCKING SIMULATION; NIACINAMIDE; OXIDATIVE STRESS; PANCREAS; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PYRAZINES; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; TRIAZOLES; TRITERPENES;

EID: 84871923480     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.10.002     Document Type: Article

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