UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1833, Issue 3, 2013, Pages 672-679

  Dando, Ilaria ^a   Fiorini, Claudia ^a   Pozza, Elisa Dalla ^a   Padroni, Chiara ^a   Costanzo, Chiara ^a   Palmieri, Marta ^a   Donadelli, Massimo ^a  

^a UNIVERSITY OF VERONA   (Italy)

Author keywords

Autophagy; Cancer; GAPDH; Genipin; ROS; UCP2

Indexed keywords

3 METHYLADENINE; CHLOROQUINE; GEMCITABINE; GENIPIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; REACTIVE OXYGEN METABOLITE; SCAVENGER; SMALL INTERFERING RNA; UNCOUPLING PROTEIN 2;

APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL;

ADENOCARCINOMA; APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CHOLAGOGUES AND CHOLERETICS; FLUORESCENT ANTIBODY TECHNIQUE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; ION CHANNELS; IRIDOIDS; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; PANCREATIC NEOPLASMS; PROTEIN TRANSPORT; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 84871914618     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2012.10.028     Document Type: Article

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