Rational design of a secreted enzymatically inactive mutant of extracellular superoxide dismutase

Redox Report

Volumn 17, Issue 6, 2012, Pages 239-245

  Case, Adam J ^a   Mezhir, James J ^a   O'Leary, Brianne R ^a   Hrabe, Jennifer E ^a   Domann, Frederick E ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Antioxidants; Free radicals; Heparan sulfate proteoglycans; Oxidative stress; Signaling proteins

Indexed keywords

AMINO ACID; EXTRACELLULAR SUPEROXIDE DISMUTASE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME RELEASE; HUMAN; HUMAN CELL; MUTANT; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CATALYSIS; CATALYTIC DOMAIN; ELECTRON SPIN RESONANCE SPECTROSCOPY; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; PROTEIN FOLDING; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; SUPEROXIDE DISMUTASE;

EID: 84871905382     PISSN: 13510002     EISSN: 17432928     Source Type: Journal    
DOI: 10.1179/1351000212Y.0000000028     Document Type: Article

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