Methanol teratogenicity in mutant mice with deficient catalase activity and transgenic mice expressing human catalase

Reproductive Toxicology

Volumn 36, Issue , 2013, Pages 33-39

  Siu, Michelle T ^a   Wiley, Michael J ^b   Wells, Peter G ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Catalase; Development; Genetically modified mice; Methanol; Reactive oxygen species

Indexed keywords

CATALASE; FORMIC ACID; METHANOL; REACTIVE OXYGEN METABOLITE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLEFT PALATE; CONTROLLED STUDY; DISEASE PREDISPOSITION; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; ENZYME DEFICIENCY; EYE MALFORMATION; FEMALE; LIVER LEVEL; MOUSE; MOUSE MUTANT; MOUSE STRAIN; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TERATOGENICITY; TISSUE DISTRIBUTION; TOXICOKINETICS; TRANSGENIC MOUSE; WILD TYPE;

ABNORMALITIES, DRUG-INDUCED; ABNORMALITIES, MULTIPLE; ACATALASIA; ANIMALS; CATALASE; EMBRYO, MAMMALIAN; FEMALE; HUMANS; LIVER; MALE; MATERNAL EXPOSURE; METHANOL; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICE, TRANSGENIC; PREGNANCY; SOLVENTS; TERATOGENS;

MUS; MUS MUSCULUS; RODENTIA;

EID: 84871895265     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2012.11.006     Document Type: Article

References (40)

1. Anderson P., Cremona A., Wallace P. What are safe levels of alcohol consumption?. British Medical Journal (Clinical Research Ed.) 1984, 289(6459):1657-1658.
2. Reed T.B., Lerner R.M., Methanol A versatile fuel for immediate use: methanol can be made from gas, coal, or wood It is stored and used in existing equipment. Science 1973, 182(4119):1299-1304.
3. Clary J.J. Methanol, is it a developmental risk to humans?. Regulatory Toxicology and Pharmacology 2003, 37(1):83-91.
4. Cederbaum A.I., Qureshi A. Role of catalase and hydroxyl radicals in the oxidation of methanol by rat liver microsomes. Biochemical Pharmacology 1982, 31(3):35-329.
5. Bradford B.U., Seed C.B., Handler J.A., Forman D.T., Thurman R.G. Evidence that catalase is a major pathway of ethanol oxidation in vivo: dose-response studies in deer mice using methanol as a selective substrate. Archives of Biochemistry and Biophysics 1993, 303(1):172-176.
6. Karinje K.U., Ogata M. Methanol metabolism in acatalasemic mice. Physiological Chemistry and Physics and Medical NMR 1990, 22(4):193-198.
7. Johlin F.C., Fortman C.S., Nghiem D.D., Tephly T.R. Studies on the role of folic acid and folate-dependent enzymes in human methanol poisoning. Molecular Pharmacology 1987, 31(5):61-557.
8. Lanigan S. Final report on the safety assessment of methyl alcohol. International Journal of Toxicology 2001, 20(Suppl. 1):57-85.
9. Wallage H.R., Watterson J.H. Formic acid and methanol concentrations in death investigations. Journal of Analytical Toxicology 2008, 32(3):7-241.
10. Harris C., Dixon M., Hansen J.M. Glutathione depletion modulates methanol formaldehyde and formate toxicity in cultured rat conceptuses. Cell Biology and Toxicology 2004, 20(3):45-133.
11. Roe O. Species differences in methanol poisoning. Critical Reviews in Toxicology 1982, 10(4):86-275.
12. Bolon B., Welsch F., Morgan K.T. Methanol-induced neural tube defects in mice: pathogenesis during neurulation. Teratology 1994, 49(6):497-517.
13. Rogers J.M., Brannen K.C., Barbee B.D., Zucker R.M., Degitz S.J. Methanol exposure during gastrulation causes holoprosencephaly, facial dysgenesis, and cervical vertebral malformations in C57BL/6J mice. Birth Defects Research: Part B, Developmental and Reproductive Toxicology 2004, 71(2):8-80.
14. Rogers J.M., Mole M.L. Critical periods of sensitivity to the developmental toxicity of inhaled methanol in the CD-1 mouse. Teratology 1997, 55(6):72-364.
15. Wells P.G., McCallum G.P., Chen C.S., Henderson J.T., Lee C.J., Perstin J., et al. Oxidative stress in developmental origins of disease: teratogenesis, neurodevelopmental deficits, and cancer. Toxicological Sciences 2009, 108(1):4-18.
16. Parthasarathy N.J., Kumar R.S., Manikandan S., Devi R.S. Methanol-induced oxidative stress in rat lymphoid organs. Journal of Occupational Health 2006, 48(1):7-20.
17. Winn L.M., Wells P.G. Phenytoin-initiated DNA oxidation in murine embryo culture, and embryo protection by the antioxidative enzymes superoxide dismutase and catalase: evidence for reactive oxygen species-mediated DNA oxidation in the molecular mechanism of phenytoin teratogenicity. Molecular Pharmacology 1995, 48(1):112-120.
18. Winn L.M., Wells P.G. Evidence for embryonic prostaglandin H synthase-catalyzed bioactivation and reactive oxygen species-mediated oxidation of cellular macromolecules in phenytoin and benzo[a]pyrene teratogenesis. Free Radical Biology and Medicine 1997, 22(4):21-607.
19. Winn L.M., Wells P.G. Maternal administration of superoxide dismutase and catalase in phenytoin teratogenicity. Free Radical Biology and Medicine 1999, 26(3-4):74-266.
20. Abramov J.P., Wells P.G. Embryoprotective role of endogenous catalase in acatalasemic and human catalase-expressing mouse embryos exposed in culture to developmental and phenytoin-enhanced oxidative stress. Toxicological Sciences 2011, 120(2):38-428.
21. Abramov J.P., Wells P.G. Embryonic catalase protects against endogenous and phenytoin-enhanced DNA oxidation and embryopathies in acatalasemic and human catalase-expressing mice. FASEB Journal 2011, 25(7):2188-2200.
22. Sweeting J.N., Siu M., Wiley M.J., Wells P.G. Species- and strain-dependent teratogenicity of methanol in rabbits and mice. Reproductive Toxicology 2011, 31(1):8-50.
23. Miller L., Wells P.G. Altered methanol embryopathies in embryo culture with mutant catalase-deficient mice and transgenic mice expressing human catalase. Toxicology and Applied Pharmacology 2011, 252(1):55-61.
24. Miller L., Wells P.G. Methanol embryopathies in mouse embryo culture following pretreatment with a free radical spin trapping agent and inhibitors of prostaglandin H synthase and NADPH oxidases. Toxicological Sciences (The Toxicologist Supplement) 2012, 126(1):417-418. (No.1940).
25. Fraser A.D., MacNeil W. Gas chromatographic analysis of methyl formate and application in methanol poisoning cases. Journal of Analytical Toxicology 1989, 13(2):6-73.
26. Porter W.H., Moyer T.P. Determination of alcohols by headspace analysis. Tietz Textbook of Clinical Chemistry 1994, 1173-1174. W.B. Saunders Company, Philadelphia. C.A. Burtis, E.R. AShwood (Eds.).
27. Jiang Z.Y., Hunt J.V., Wolff S.P. Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxide in low density lipoprotein. Analytical Biochemistry 1992, 202(2):9-384.
28. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 1976, 72:54-248.
29. Yuan J. Estimation of variance for AUC in animal studies. Journal of Pharmaceutical Sciences 1993, 82(7):3-761.
30. Sweeting J.N., Siu M., McCallum G.P., Miller L., Wells P.G. Species differences in methanol and formic acid pharmacokinetics in mice, rabbits and primates. Toxicology and Applied Pharmacology 2010, 247(1):28-35.
31. NTP, NTP-CERHR expert panel report on the reproductive and developmental toxicity of methanol. National Toxicology Program, U.S. Department of Health and Human Services; 2002.
32. Sulik K.K., Johnston M.C., Webb M.A. Fetal alcohol syndrome: embryogenesis in a mouse model. Science 1981, 214(4523):8-936.
33. Mani J.C., Pietruszko R., Theorell H. Methanol activity of alcohol dehydrogenases from human liver, horse liver, and yeast. Archives of Biochemistry and Biophysics 1970, 140(1):9-52.
34. NEDO, Toxicological research on methanol as a fuel for power stations: a summary report on test with monkeys, rats and mice. New Energy and Industrial Developmental Organization, Japan; 1986.
35. NEDO, Toxicological research on methanol as a fuel for power stations: a summary report on test with monkeys, rats and mice. New Energy and Industrial Developmental Organization, Japan; 1987.
36. Castro G.D., Costantini M.H., Delgado de Layno A.M., Castro J.A. Rat liver microsomal and nuclear activation of methanol to hydroxymethyl free radicals. Toxicology Letters 2002, 129(3):36-227.
37. Kadiiska M.B., Mason R.P. Acute methanol intoxication generates free radicals in rats: an ESR spin trapping investigation. Free Radical Biology and Medicine 2000, 28(7):14-1106.
38. Skrzydlewska E., Elas M., Farbiszewski R., Roszkowska A. Effect of methanol intoxication on free-radical induced protein oxidation. Journal of Applied Toxicology 2000, 20(3):43-239.
39. McCallum G.P., Siu M., Ondovcik S., Sweeting J.N., Wells P.G. Methanol exposure does not lead to accumulation of oxidative DNA damage in bone marrow or spleen of mice, rabbits or primates. Molecular Carcinogenesis 2011, 50:163-172.
40. McCallum G.P., Siu M., Sweeting J.N., Wells P.G. Methanol exposure does not produce oxidatively damaged DNA in lung, liver or kidney of adult mice, rabbits or primates. Toxicology and Applied Pharmacology 2011, 250:147-153.