Altered methanol embryopathies in embryo culture with mutant catalase-deficient mice and transgenic mice expressing human catalase

Toxicology and Applied Pharmacology

Volumn 252, Issue 1, 2011, Pages 55-61

  Miller, Lutfiya ^a   Wells, Peter G ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Catalase; Embryopathies; Methanol; Mutant mice; Reactive oxygen species; Teratogenesis; Transgenic mice

Indexed keywords

CATALASE; METHANOL; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO CULTURE; EMBRYOPATHY; ENZYME ACTIVITY; FEMALE; GESTATIONAL AGE; HEAD; MALE; MOUSE; MOUSE MUTANT; NONHUMAN; RISK FACTOR; TERATOGENICITY; TRANSGENIC MOUSE; WILD TYPE; YOLK SAC;

ACATALASIA; ANIMALS; CATALASE; EMBRYO, MAMMALIAN; FEMALE; FETAL DISEASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; METHANOL; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; PREGNANCY;

MUS; MUS MUSCULUS; RODENTIA;

EID: 79952619247     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.01.019     Document Type: Article

References (31)

1. Abbott B.D., Ebron-McCoy M., Andrews J.E. Cell death in rat and mouse embryos exposed to methanol in whole embryo culture. Toxicology 1995, 97:159-171.
2. Abramov, J.P., Wells, P.G., in press. Embryoprotective role of endogenous catalase in acatalasemic and human catalase-expressing mouse embryos exposed in culture to developmental and phenytoin-enhanced oxidative stress. Toxicol. Sci.
3. Andrews J.E., Ebron-McCoy M., Logsdon T.R., Mole L.M., Kavlock R.J., Rogers J.M. Developmental toxicity of methanol in whole embryo culture: a comparative study with mouse and rat embryos. Toxicology 1993, 81:205-215.
4. Cederberg J., Eriksson U.J. Decreased catalase activity in malformation-prone embryos of diabetic rats. Teratology 1997, 56:350-357.
5. Chen X., Mele J., Giese H., Van Remmen H., Dolle M.E., Steinhelper M., Richardson A., Vijg J. A strategy for the ubiquitous overexpression of human catalase and CuZn superoxide dismutase genes in transgenic mice. Mech. Ageing Dev. 2003, 124:219-227.
6. Chen S.Y., Dehart D.B., Sulik K.K. Protection from ethanol-induced limb malformations by the superoxide dismutase/catalase mimetic, EUK-134. FASEB J. 2004, 18:1234-1236.
7. Degitz S.J., Rogers J.M., Zucker R.M., Hunter E.S. Developmental toxicity of methanol: pathogenesis in CD-1 and C57BL/6J mice exposed in whole embryo culture. Birth Defects Res. Clin. Mol. Teratol. 2004, 70:179-184.
8. Degitz S.J., Zucker R.M., Kawanishi C.Y., Massenburg G.S., Rogers J.M. Pathogenesis of methanol-induced craniofacial defects in C57BL/6J mice. Birth Defects Res. Clin. Mol. Teratol. 2004, 70:172-178.
9. Dorman D.C., Bolon B., Struve M.F., LaPerle K.M.D., Wong B.A., Elswick B., Welsch F. Role of formate in methanol-induced exencephaly in CD-1 mice. Teratology 1995, 52:30-40.
10. Halliwell B., Gutteridge J. Free Radicals in Biology and Medicine 2007, Oxford University Press, Oxford. 4th ed.
11. Hansen J., Contreras K.M., Harris C. Methanol, formaldehyde, and sodium formate exposure in rat and mouse conceptuses: a potential role of the visceral yolk sac in embryotoxicity. Birth Defects Res. Clin. Mol. Teratol. 2005, 73:72-82.
12. Harris C., Dixon M., Hansen J.M. Glutathione depletion modulates methanol, formaldehyde and formate toxicity in cultured rat conceptuses. Cell Biol. Toxicol. 2004, 20:133-145.
13. Kadiiska M.B., Mason R.P. Acute methanol intoxication generates free radicals in rats: an ESR spin trapping investigation. Free Radic. Biol. Med. 2000, 28:1106-1114.
14. Moore K., Persaud T.V.N. The Developing Human: Clinically Oriented Embryology 2007, W.B Saunders, Philadelphia, USA. 8th ed.
15. Nelson B.K., Brightwell W.S., MacKenzie D.R., Khan A., Burg J.R., Weigel W.W., Goad P.T. Teratological assessment of methanol and ethanol at high inhalation levels in rats. Fundam. Appl. Toxicol. 1985, 5:727-736.
16. Nicol C.J., Zielenski J., Tsui L.C., Wells P.G. An embryoprotective role for glucose-6-phosphate dehydrogenase in developmental oxidative stress and chemical teratogenesis. FASEB J. 2000, 14:111-127.
17. Parthasarathy N., Kumar R.S., Manikandan S., Devi R.S. Methanol-induced oxidative stress in rat lymphoid organs. J. Occup. Health 2006, 48:20-27.
18. Peng Y., Yang P.H., Guo Y., Ng S.S., Liu J., Fung P.C., Tay D., Ge J., He M.L., Kung H.F., Lin M.C. Catalase and peroxiredoxin 5 protect Xenopus embryos against alcohol-induced ocular anomalies. Invest. Ophthalmol. Vis. Sci. 2004, 45:23-29.
19. Rogers J.M., Mole M.L. Critical periods of sensitivity to the developmental toxicity of inhaled methanol in the CD-1 mouse. Teratology 1997, 55:364-372.
20. Rogers J.M., Mole M.L., Chernoff N., Barbee B.D., Turner C.I., Logsdon T.R., Kavlock R.J. The developmental toxicity of inhaled methanol in the CD-1 mouse, with quantitative dose-response modeling for estimation of benchmark doses. Teratology 1993, 47:175-188.
21. Sauer H., Wartenberg M., Hescheler J. Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell. Physiol. Biochem. 2001, 11:173-186.
22. Siu M., Wells P.G. Catalase in the mechanism of methanol developmental toxicity. Toxicol. Sci. (Suppl Toxicologist) 2010, 114:183. (Abstract No. 858).
23. Skrzydlewska E., Elas M., Farbiszewski R., Roszkowska A. Effect of methanol intoxication on free-radical induced protein oxidation. J. Appl. Toxicol. 2000, 20:239-243.
24. Sparrow M.G., Roggendorf H., Vogel W.H. Effect of ethanol on heart rate and blood pressure in nonstressed and stressed rats. Life Sci. 1987, 40:2551-2559.
25. Sulik K.K. Genesis of alcohol-induced craniofacial dysmorphism. Exp. Biol. Med. (Maywood) 2005, 230:366-375.
26. Tephly T.R., Parks R.E., Mannering G.J. Methanol metabolism in the rat. J. Pharmacol. Exp. Ther. 1964, 143:292-300.
27. Ufer C., Wang C.C., Borchert A., Heydeck D., Kuhn H. Redox control in mammalian embryo development. Antioxid. Redox Signal. 2010, 13:833-875.
28. Wells P.G., McCallum G.P., Chen C.S., Henderson J.T., Lee C.J.J., Perstin J., Preston T.J., Wiley M.J., Wong A.W. Oxidative stress in developmental origins of disease: teratogenesis, neurodevelopmental deficits and cancer. Toxicol. Sci. 2009, 108:4-18.
29. Winn L.M., Wells P.G. Phenytoin-initiated DNA oxidation in murine embryo culture, and embryo protection by the antioxidative enzymes superoxide dismutase and catalase: evidence for reactive oxygen species-mediated DNA oxidation in the molecular mechanism of phenytoin teratogenicity. Mol. Pharmacol. 1995, 48:112-120.
30. Winn L.M., Wells P.G. Evidence for embryonic prostaglandin H synthase-catalyzed bioactivation and reactive oxygen species-mediated oxidation of cellular macromolecules in phenytoin and benzo[a]pyrene teratogenesis. Free Radic. Biol. Med. 1997, 22:607-621.
31. Winn L.M., Wells P.G. Maternal administration of superoxide dismutase and catalase in phenytoin teratogenicity. Free Radic. Biol. Med. 1999, 26:266-274.