Catheter-Based Intramyocardial Delivery (NavX) of Adenovirus Achieves Safe and Accurate Gene Transfer in Pigs

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Chen, Bo ^a   Tao, Zhengxian ^a   Zhao, Yingming ^a   Chen, Hongwu ^a   Yong, Yonghong ^a   Liu, Xiang ^b   Wang, Hua ^c   Wu, Zuze ^c   Yang, Zhijian ^a   Yuan, Li ^d  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b MicroPort Medical (Shanghai) Co Ltd   (China)

^c BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^d NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CREATINE KINASE MB; NITROGEN; SCATTER FACTOR; UREA;

ACCURACY; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC IMAGING; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; GATED SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; GENE EXPRESSION; HEART CATHETER; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE PERFUSION; HISTOPATHOLOGY; MALE; NONHUMAN; SWINE; UREA NITROGEN BLOOD LEVEL; VIRAL GENE THERAPY; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALS; CATHETERIZATION; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; HEART VENTRICLES; HEK293 CELLS; HEPATOCYTE GROWTH FACTOR; HUMANS; MALE; MYOCARDIAL ISCHEMIA; MYOCARDIUM; RANDOM ALLOCATION; REPRODUCIBILITY OF RESULTS; SWINE; SWINE, MINIATURE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

ADENOVIRIDAE; SUIDAE;

EID: 84871882507     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053007     Document Type: Article

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