-
1
-
-
57849109837
-
Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model
-
Alcantara Llaguno S, et al. 2009. Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell 15:45-56.
-
(2009)
Cancer Cell
, vol.15
, pp. 45-56
-
-
Llaguno, S.A.1
-
2
-
-
0029097759
-
Radiation-induced cell cycle arrest compromised by p21 deficiency
-
Brugarolas J, et al. 1995. Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377:552-557.
-
(1995)
Nature
, vol.377
, pp. 552-557
-
-
Brugarolas, J.1
-
3
-
-
0034629129
-
Hematopoietic stem cell quiescence maintained by p21cip1/waf1
-
Cheng T, et al. 2000. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science 287:1804 -1808.
-
(2000)
Science
, vol.287
-
-
Cheng, T.1
-
4
-
-
0017755665
-
The role of the subependymal plate in avian sarcoma virus brain tumor induction: comparison of incipient tumors in neonatal and adult rats
-
Copeland DD, Bigner DD. 1977. The role of the subependymal plate in avian sarcoma virus brain tumor induction: comparison of incipient tumors in neonatal and adult rats. Acta Neuropathol. 38:1- 6.
-
(1977)
Acta Neuropathol.
, vol.38
-
-
Copeland, D.D.1
Bigner, D.D.2
-
5
-
-
0016530581
-
The induction of intractranial neoplasms by the inoculation of avian sarcoma virus in perinatal and adult rats
-
Copeland DD, Vogel FS, Bigner DD. 1975. The induction of intractranial neoplasms by the inoculation of avian sarcoma virus in perinatal and adult rats. J. Neuropathol. Exp. Neurol. 34:340 -358.
-
(1975)
J. Neuropathol. Exp. Neurol.
, vol.34
-
-
Copeland, D.D.1
Vogel, F.S.2
Bigner, D.D.3
-
6
-
-
32544441224
-
Loss of p53 induces changes in the behavior of subventricular zone cells: implication for the genesis of glial tumors
-
Gil-Perotin S, et al. 2006. Loss of p53 induces changes in the behavior of subventricular zone cells: implication for the genesis of glial tumors. J. Neurosci. 26:1107-1116.
-
(2006)
J. Neurosci.
, vol.26
, pp. 1107-1116
-
-
Gil-perotin, S.1
-
7
-
-
0035824396
-
Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo
-
Groszer M, et al. 2001. Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo. Science 294: 2186-2189.
-
(2001)
Science
, vol.294
, pp. 2186-2189
-
-
Groszer, M.1
-
8
-
-
80052559874
-
The probable cell of origin of NF1- and PDGF-driven glioblastomas
-
doi:10.1371/journal.pone.0024454
-
Hambardzumyan D, Cheng YK, Haeno H, Holland EC, Michor F. 2011. The probable cell of origin of NF1- and PDGF-driven glioblastomas. PLoS One 6:e24454. doi:10.1371/journal.pone.0024454.
-
(2011)
PLoS One
, vol.6
-
-
Hambardzumyan, D.1
Cheng, Y.K.2
Haeno, H.3
Holland, E.C.4
Michor, F.5
-
9
-
-
79957927593
-
Genetic modeling of gliomas in mice: new tools to tackle old problems
-
Hambardzumyan D, Parada LF, Holland EC, Charest A. 2011. Genetic modeling of gliomas in mice: new tools to tackle old problems. Glia 59: 1155-1168.
-
(2011)
Glia
, vol.59
, pp. 1155-1168
-
-
Hambardzumyan, D.1
Parada, L.F.2
Holland, E.C.3
Charest, A.4
-
10
-
-
0028118111
-
Tumor spectrum analysis in p53-mutant mice
-
Jacks T, et al. 1994. Tumor spectrum analysis in p53-mutant mice. Curr. Biol. 4:1-7.
-
(1994)
Curr. Biol.
, vol.4
, pp. 1-7
-
-
Jacks, T.1
-
11
-
-
75649109727
-
Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes
-
Jacques TS, et al. 2010. Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes. EMBO J. 29:222-235.
-
(2010)
EMBO J.
, vol.29
, pp. 222-235
-
-
Jacques, T.S.1
-
12
-
-
67651036549
-
The glial nature of embryonic and adult neural stem cells
-
Kriegstein A, Alvarez-Buylla A. 2009. The glial nature of embryonic and adult neural stem cells. Annu. Rev. Neurosci. 32:149 -184.
-
(2009)
Annu. Rev. Neurosci.
, vol.32
-
-
Kriegstein, A.1
Alvarez-buylla, A.2
-
13
-
-
79955031521
-
Seeing is believing: are cancer stem cells the Loch Ness monster of tumor biology?
-
Lathia JD, Venere M, Rao MS, Rich JN. 2011. Seeing is believing: are cancer stem cells the Loch Ness monster of tumor biology? Stem Cell Rev. 7:227-237.
-
(2011)
Stem Cell Rev
, vol.7
, pp. 227-237
-
-
Lathia, J.D.1
Venere, M.2
Rao, M.S.3
Rich, J.N.4
-
14
-
-
0035857068
-
Neural precursor cell apoptosis and glial tumorigenesis following transplacental ethylnitrosourea exposure
-
Leonard JR, D'Sa C, Klocke BJ, Roth KA. 2001. Neural precursor cell apoptosis and glial tumorigenesis following transplacental ethylnitrosourea exposure. Oncogene 20:8281- 8286.
-
(2001)
Oncogene
, vol.20
-
-
Leonard, J.R.1
D'sa, C.2
Klocke, B.J.3
Roth, K.A.4
-
15
-
-
38049046645
-
Nuclear receptor TLX regulates cell cycle progression in neural stem cells of the developing brain
-
Li W, et al. 2008. Nuclear receptor TLX regulates cell cycle progression in neural stem cells of the developing brain. Mol. Endocrinol. 22:56-64.
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 56-64
-
-
Li, W.1
-
16
-
-
79960809488
-
Mosaic analysis with double markers reveals tumor cell of origin in glioma
-
Liu C, et al. 2011. Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell 146:209 -221.
-
(2011)
Cell
, vol.146
-
-
Liu, C.1
-
17
-
-
51949086947
-
The nuclear receptor tailless is required for neurogenesis in the adult subventricular zone
-
Liu HK, et al. 2008. The nuclear receptor tailless is required for neurogenesis in the adult subventricular zone. Genes Dev. 22:2473-2478.
-
(2008)
Genes Dev.
, vol.22
, pp. 2473-2478
-
-
Liu, H.K.1
-
18
-
-
77950473430
-
The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation
-
Liu HK, et al. 2010. The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation. Genes Dev. 24:683- 695.
-
(2010)
Genes Dev.
, vol.24
-
-
Liu, H.K.1
-
19
-
-
58049216794
-
p53 regulates hematopoietic stem cell quiescence
-
Liu Y, et al. 2009. p53 regulates hematopoietic stem cell quiescence. Cell Stem Cell 4:37- 48.
-
(2009)
Cell Stem Cell
, vol.4
-
-
Liu, Y.1
-
20
-
-
0034656212
-
Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
-
10783170
-
Marino S, Vooijs M, van Der Gulden H, Jonkers J, Berns A. 2000. Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev. 14:994 -1004. 10783170.
-
(2000)
Genes Dev.
, vol.14
-
-
Marino, S.1
Vooijs, M.2
van der Gulden, H.3
Jonkers, J.4
Berns, A.5
-
21
-
-
58149330085
-
Development of a novel mouse glioma model using lentiviral vectors
-
Marumoto T, et al. 2009. Development of a novel mouse glioma model using lentiviral vectors. Nat. Med. 15:110 -116.
-
(2009)
Nat. Med.
, vol.15
-
-
Marumoto, T.1
-
22
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
McLendon R, et al. 2008. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455:1061- 1068.
-
(2008)
Nature
, vol.455
-
-
Mclendon, R.1
-
23
-
-
32244436592
-
p53 suppresses the self-renewal of adult neural stem cells
-
Meletis K, et al. 2006. p53 suppresses the self-renewal of adult neural stem cells. Development 133:363-369.
-
(2006)
Development
, vol.133
, pp. 363-369
-
-
Meletis, K.1
-
24
-
-
79956209852
-
Adult neurogenesis in the mammalian brain: significant answers and significant questions
-
Ming GL, Song H. 2011. Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron 70:687-702.
-
(2011)
Neuron
, vol.70
, pp. 687-702
-
-
Ming, G.L.1
Song, H.2
-
25
-
-
0028935673
-
The mouse homolog of the orphan nuclear receptor tailless is expressed in the developing forebrain
-
Monaghan AP, Grau E, Bock D, Schutz G. 1995. The mouse homolog of the orphan nuclear receptor tailless is expressed in the developing forebrain. Development 121:839-853.
-
(1995)
Development
, vol.121
, pp. 839-853
-
-
Monaghan, A.P.1
Grau, E.2
Bock, D.3
Schutz, G.4
-
26
-
-
80053277715
-
Activation of postnatal neural stem cells requires nuclear receptor TLX
-
Niu W, Zou Y, Shen C, Zhang CL. 2011. Activation of postnatal neural stem cells requires nuclear receptor TLX. J. Neurosci. 31:13816 -13828.
-
(2011)
J. Neurosci.
, vol.31
-
-
Niu, W.1
Zou, Y.2
Shen, C.3
Zhang, C.L.4
-
27
-
-
0031045758
-
Loss of p53 is an early event in induction of brain tumors in mice by transplacental carcinogen exposure
-
Oda H, et al. 1997. Loss of p53 is an early event in induction of brain tumors in mice by transplacental carcinogen exposure. Cancer Res. 57: 646-650.
-
(1997)
Cancer Res.
, vol.57
, pp. 646-650
-
-
Oda, H.1
-
28
-
-
78650509569
-
The neural stem cell fate determinant TLX promotes tumorigenesis and genesis of cells resembling glioma stem cells
-
Park HJ, et al. 2010. The neural stem cell fate determinant TLX promotes tumorigenesis and genesis of cells resembling glioma stem cells. Mol. Cells 30:403- 408.
-
(2010)
Mol. Cells
, vol.30
-
-
Park, H.J.1
-
29
-
-
60749090193
-
Loss of p21 CDKN1A impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence
-
Perucca P, et al. 2009. Loss of p21 CDKN1A impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence. Cell Cycle 8:105-114.
-
(2009)
Cell Cycle
, vol.8
, pp. 105-114
-
-
Perucca, P.1
-
30
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
Phillips HS, et al. 2006. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9:157-173.
-
(2006)
Cancer Cell
, vol.9
, pp. 157-173
-
-
Phillips, H.S.1
-
31
-
-
84862932899
-
Dysregulation of Kruppel-like factor 4 during brain development leads to hydrocephalus in mice
-
Qin S, Liu M, Niu W, Zhang CL. 2011. Dysregulation of Kruppel-like factor 4 during brain development leads to hydrocephalus in mice. Proc. Natl. Acad. Sci. U. S. A. 108:21117-21121.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 21117-21121
-
-
Qin, S.1
Liu, M.2
Niu, W.3
Zhang, C.L.4
-
32
-
-
0347719238
-
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
-
Shi Y, et al. 2004. Expression and function of orphan nuclear receptor TLX in adult neural stem cells. Nature 427:78-83.
-
(2004)
Nature
, vol.427
, pp. 78-83
-
-
Shi, Y.1
-
33
-
-
79957462240
-
Alpha-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1
-
doi:10.1126/scisignal.2001823
-
Silvis MR, et al. 2011. Alpha-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1. Sci. Signal. 4:ra33. doi:10.1126/scisignal.2001823.
-
(2011)
Sci. Signal.
, vol.4
-
-
Silvis, M.R.1
-
34
-
-
33845237850
-
Neurocytoma is a tumor of adult neuronal progenitor cells
-
Sim FJ, et al. 2006. Neurocytoma is a tumor of adult neuronal progenitor cells. J. Neurosci. 26:12544 -12555.
-
(2006)
J. Neurosci.
, vol.26
-
-
Sim, F.J.1
-
36
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh SK, et al. 2003. Identification of a cancer stem cell in human brain tumors. Cancer Res. 63:5821-5828.
-
(2003)
Cancer Res.
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
-
37
-
-
45249119952
-
Glioma stem cells: a midterm exam
-
Stiles CD, Rowitch DH. 2008. Glioma stem cells: a midterm exam. Neuron 58:832- 846.
-
(2008)
Neuron
, vol.58
-
-
Stiles, C.D.1
Rowitch, D.H.2
-
38
-
-
80052574196
-
Asymmetry-defective oligodendrocyte progenitors are glioma precursors
-
Sugiarto S, et al. 2011. Asymmetry-defective oligodendrocyte progenitors are glioma precursors. Cancer Cell 20:328 -340.
-
(2011)
Cancer Cell
, vol.20
-
-
Sugiarto, S.1
-
40
-
-
79960774446
-
Glioma development: where did it all go wrong?
-
Sukhdeo K, Hambardzumyan D, Rich JN. 2011. Glioma development: where did it all go wrong?. Cell 146:187-188.
-
(2011)
Cell
, vol.146
, pp. 187-188
-
-
Sukhdeo, K.1
Hambardzumyan, D.2
Rich, J.N.3
-
41
-
-
34848818037
-
Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation
-
Sun G, Yu RT, Evans RM, Shi Y. 2007. Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation. Proc. Natl. Acad. Sci. U. S. A. 104:15282-15287.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 15282-15287
-
-
Sun, G.1
Yu, R.T.2
Evans, R.M.3
Shi, Y.4
-
42
-
-
26644435531
-
Radial glia cells are candidate stem cells of ependymoma
-
Taylor MD, et al. 2005. Radial glia cells are candidate stem cells of ependymoma. Cancer Cell 8:323-335.
-
(2005)
Cancer Cell
, vol.8
, pp. 323-335
-
-
Taylor, M.D.1
-
43
-
-
65649142176
-
Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model
-
Wang Y, et al. 2009. Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model. Cancer Cell 15:514 -526.
-
(2009)
Cancer Cell
, vol.15
-
-
Wang, Y.1
-
44
-
-
0034646231
-
The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision
-
Yu RT, et al. 2000. The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision. Proc. Natl. Acad. Sci. U. S. A. 97:2621-2625.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 2621-2625
-
-
Yu, R.T.1
-
45
-
-
0027992358
-
Relationship between Drosophila gap gene tailless and a vertebrate nuclear receptor Tlx
-
Yu RT, McKeown M, Evans RM, Umesono K. 1994. Relationship between Drosophila gap gene tailless and a vertebrate nuclear receptor Tlx. Nature 370:375-379.
-
(1994)
Nature
, vol.370
, pp. 375-379
-
-
Yu, R.T.1
Mckeown, M.2
Evans, R.M.3
Umesono, K.4
-
46
-
-
39149099035
-
A role for adult TLX-positive neural stem cells in learning and behaviour
-
Zhang CL, Zou Y, He W, Gage FH, Evans RM. 2008. A role for adult TLX-positive neural stem cells in learning and behaviour. Nature 451: 1004-1007.
-
(2008)
Nature
, vol.451
, pp. 1004-1007
-
-
Zhang, C.L.1
Zou, Y.2
He, W.3
Gage, F.H.4
Evans, R.M.5
-
47
-
-
33646545699
-
Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1
-
Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM. 2006. Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev. 20:1308 -1320.
-
(2006)
Genes Dev.
, vol.20
-
-
Zhang, C.L.1
Zou, Y.2
Yu, R.T.3
Gage, F.H.4
Evans, R.M.5
-
48
-
-
54549095950
-
p53 and Pten control neural and glioma stem/ progenitor cell renewal and differentiation
-
Zheng H, et al. 2008. p53 and Pten control neural and glioma stem/ progenitor cell renewal and differentiation. Nature 455:1129 -1133.
-
(2008)
Nature
, vol.455
-
-
Zheng, H.1
-
49
-
-
23644443053
-
Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma
-
Zhu Y, et al. 2005. Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. Cancer Cell 8:119 -130.
-
(2005)
Cancer Cell
, vol.8
-
-
Zhu, Y.1
-
50
-
-
0035170704
-
hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo
-
Zhuo L, et al. 2001. hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo. Genesis 31:85-94.
-
(2001)
Genesis
, vol.31
, pp. 85-94
-
-
Zhuo, L.1
|