Characterization of the AggR regulon in enteroaggregative Escherichia coli

Infection and Immunity

Volumn 81, Issue 1, 2013, Pages 122-132

  Morin, Nicholas ^a   Santiago, Araceli E ^b   Ernst, Robert K ^c   Guillot, Stacey J ^b   Nataro, James P ^b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGR PROTEIN; ASPARTIC ACID; ESCHERICHIA COLI PROTEIN; ISOPRENOID; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL VIRULENCE; BIOSYNTHESIS; DNA MICROARRAY; ENTEROAGGREGATIVE ESCHERICHIA COLI; GENE EXPRESSION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PLASMID; PRIORITY JOURNAL; PROTEIN ANALYSIS; QUANTITATIVE ASSAY; REAL TIME POLYMERASE CHAIN REACTION; REGULON;

ASPARTIC ACID; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OPEN READING FRAMES; TRANS-ACTIVATORS; VIRULENCE FACTORS;

EID: 84871874238     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00676-12     Document Type: Article

References (37)

1. Huang DB, Nataro JP, DuPont HL, Kamat PP, Mhatre AD, Okhuysen PC, Chiang T. 2006. Enteroaggregative Escherichia coli is a cause of acute diarrheal illness: a meta-analysis. Clin. Infect. Dis. 43:556-563.
2. Nataro JP, Mai V, Johnson J, Blackwelder WC, Heimer R, Tirrell S, Edberg SC, Braden CR, Glenn MJ, Jr, Hirshon JM. 2006. Diarrheagenic Escherichia coli infection in Baltimore, Maryland, and New Haven, Connecticut. Clin. Infect. Dis. 43:402-407.
3. Nataro JP, Steiner T, Guerrant RL. 1998. Enteroaggregative Escherichia coli. Emerg. Infect. Dis. 4:251-261.
4. Okeke IN, Lamikanra A, Czeczulin J, Dubovsky F, Kaper JB, Nataro JP. 2000. Heterogeneous virulence of enteroaggregative Escherichia coli strains isolated from children in Southwest Nigeria. J. Infect. Dis. 181: 252-260.
5. Weintraub A. 2007. Enteroaggregative Escherichia coli: epidemiology, virulence and detection. J. Med. Microbiol. 56:4-8.
6. Nataro JP. 2011. Outbreak of hemolytic-uremic syndrome linked to Shiga toxin-producing enteroaggregative Escherichia coli O104:H4. Pediatr. Res. 70:221.
7. Rasko DA, Webster DR, Sahl JW, Bashir A, Boisen N, Scheutz F, Paxinos EE, Sebra R, Chin CS, Iliopoulos D, Klammer A, Peluso P, Lee L, Kislyuk AO, Bullard J, Kasarskis A, Wang S, Eid J, Rank D, Redman JC, Steyert SR, Frimodt-Moller J, Struve C, Petersen AM, Krogfelt KA, Nataro JP, Schadt EE, Waldor MK. 2011. Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany. N. Engl. J. Med. 365:709-717.
8. Jiang ZD, Greenberg D, Nataro JP, Steffen R, DuPont HL. 2002. Rate of occurrence and pathogenic effect of enteroaggregative Escherichia coli virulence factors in international travelers. J. Clin. Microbiol. 40:4185-4190.
9. Vila J, Vargas M, Henderson IR, Gascon J, Nataro JP. 2000. Enteroaggregative Escherichia coli virulence factors in traveler's diarrhea strains. J. Infect. Dis. 182:1780-1783.
10. Gallegos MT, Michan C, Ramos JL. 1993. The XylS/AraC family of regulators. Nucleic Acids Res. 21:807-810.
11. Nataro JP, Yikang D, Yingkang D, Walker K. 1994. AggR, a transcriptional activator of aggregative adherence fimbria I expression in enteroaggregative Escherichia coli. J. Bacteriol. 176:4691-4699.
12. Cennimo D, Abbas A, Huang DB, Chiang T. 2009. The prevalence and virulence characteristics of enteroaggregative Escherichia coli at an urgent-care clinic in the USA: a case-control study. J. Med. Microbiol. 58:403-407.
13. Huang DB, Mohamed JA, Nataro JP, DuPont HL, Jiang ZD, Okhuysen PC. 2007. Virulence characteristics and the molecular epidemiology of enteroaggregative Escherichia coli isolates from travellers to developing countries. J. Med. Microbiol. 56:1386-1392.
14. Sheikh J, Czeczulin JR, Harrington S, Hicks S, Henderson IR, Le Bouguenec C, Gounon P, Phillips A, Nataro JP. 2002. A novel dispersin protein in enteroaggregative Escherichia coli. J. Clin. Invest. 110:1329-1337.
15. Nishi J, Sheikh J, Mizuguchi K, Luisi B, Burland V, Boutin A, Rose DJ, Blattner FR, Nataro JP. 2003. The export of coat protein from enteroaggregative Escherichia coli by a specific ATP-binding cassette transporter system. J. Biol. Chem. 278:45680-45689.
16. Dudley EG, Thomson NR, Parkhill J, Morin NP, Nataro JP. 2006. Proteomic and microarray characterization of the AggR regulon identifies a pheU pathogenicity island in enteroaggregative Escherichia coli. Mol. Microbiol. 61:1267-1282.
17. Nataro JP, Deng Y, Cookson S, Cravioto A, Savarino SJ, Guers LD, Levine MM, Tacket CO. 1995. Heterogeneity of enteroaggregative Escherichia coli virulence demonstrated in volunteers. J. Infect. Dis. 171:465-468.
18. Sheikh J, Hicks S, Dall'Agnol M, Phillips AD, Nataro JP. 2001. Roles for Fis and YafK in biofilm formation by enteroaggregative Escherichia coli. Mol. Microbiol. 41:983-997.
19. Datsenko KA, Wanner BL. 2000. One-step inactivation of chromosomalgenes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. U. S. A. 97:6640-6645.
20. Tusher VG, Tibshirani R, Chu G. 2001. Significance analysis of microar-rays applied to the ionizing radiation response. Proc. Natl. Acad. U. S. A. 98:5116-5121.
21. Ruiz-Perez F, Sheikh J, Davis S, Boedeker EC, Nataro JP. 2004. Use of a continuous-flow anaerobic culture to characterize enteric virulence gene expression. Infect. Immun. 72:3793-3802.
22. El Hamidi A, Tirsoaga A, Novikov A, Hussein A, Caroff M. 2005. Microextraction of bacterial lipid A: easy and rapid method for mass spec-trometric characterization. J. Lipid Res. 46:1773-1778.
23. Zimmer DP, Soupene E, Lee HL, Wendisch VF, Khodursky AB, Peter BJ, Bender RA, Kustu S. 2000. Nitrogen regulatory protein C-controlled genes of Escherichia coli: scavenging as a defense against nitrogen limitation. Proc. Natl. Acad. Sci. U. S. A. 97:14674-14679.
24. Lee S, Poulter CD. 2006. Escherichia coli type I isopentenyl diphosphate isomerase: structural and catalytic roles for divalent metals. J. Am. Chem. Soc. 128:11545-11550.
25. Levine MM, Bergquist EJ, Nalin DR, Waterman DH, Hornick RB, Young CR, Sotman S. 1978. Escherichia coli strains that cause diarrhoea but do not produce heat-labile or heat-stable enterotoxins and are noninvasive. Lancet i:1119-1122.
26. Elias WP, JR, Czeczulin JR, Henderson IR, Trabulsi LR, Nataro JP. 1999. Organization of biogenesis genes for aggregative adherence fimbria II defines a virulence gene cluster in enteroaggregative Escherichia coli. J. Bacteriol. 181:1779-1785.
27. Morin N, Tirling C, Ivison SM, Kaur AP, Nataro JP, Steiner TS. 2010. Autoactivation of the AggR regulator of enteroaggregative Escherichia coli in vitro and in vivo. FEMS Immunol. Med. Microbiol. 58:344-355.
28. Czeczulin JR, Whittam TS, Henderson IR, Navarro-Garcia F, Nataro JP. 1999. Phylogenetic analysis of enteroaggregative and diffusely adherent Escherichia coli. Infect. Immun. 67:2692-2699.
29. Eisenreich W, Bacher A, Arigoni D, Rohdich F. 2004. Biosynthesis of isoprenoids via the non-mevalonate pathway. Cell Mol. Life Sci. 61:1401-1426.
30. Lichtenthaler HK. 2000. Non-mevalonate isoprenoid biosynthesis: enzymes, genes and inhibitors. Biochem. Soc. Trans. 28:785-789.
31. Ohnuma S, Hirooka K, Hemmi H, Ishida C, Ohto C, Nishino T. 1996. Conversion of product specificity of archaebacterial geranylgeranyldiphosphate synthase. Identification of essential amino acid residues for chain length determination of prenyltransferase reaction. J. Biol. Chem. 271:18831-18837.
32. Casey PJ, Seabra MC. 1996. Protein prenyltransferases. J. Biol. Chem. 271:5289-5292.
33. Liang PH, Ko TP, Wang AH. 2002. Structure, mechanism and function of prenyltransferases. Eur. J. Biochem. 269:3339-3354.
34. Lu YP, Liu HG, Liang PH. 2009. Different reaction mechanisms for cis-and trans-prenyltransferases. Biochem. Biophys. Res. Commun. 379:351-355.
35. Yokoyama K, Goodwin GW, Ghomashchi F, Glomset J, Gelb MH. 1992. Protein prenyltransferases. Biochem. Soc. Trans. 20:489-494.
36. Ellis TN, Kuehn MJ. 2010. Virulence and immunomodulatory roles of bacterial outer membrane vesicles. Microbiol. Mol. Biol. Rev. 74:81-94.
37. McBroom AJ, Kuehn MJ. 2007. Release of outer membrane vesicles by Gram-negative bacteria is a novel envelope stress response. Mol. Micro-biol. 63:545-558.