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Volumn 43, Issue , 2013, Pages 14-22

Interleukin-6-induced S100B secretion is inhibited by haloperidol and risperidone

Author keywords

Antipsychotics; Cytokines; Glia; S100B; Schizophrenia

Indexed keywords

GLUTATHIONE; HALOPERIDOL; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PROTEIN S100B; RISPERIDONE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84871858574     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2012.12.001     Document Type: Article
Times cited : (58)

References (59)
  • 2
    • 0030031869 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein-immunoreactive astrocytosis in elderly patients with schizophrenia and dementia
    • Arnold S.E., Franz B.R., Trojanowski J.Q., Moberg P.J., Gur R.E. Glial fibrillary acidic protein-immunoreactive astrocytosis in elderly patients with schizophrenia and dementia. Acta Neuropathol 1996, 91:269-277.
    • (1996) Acta Neuropathol , vol.91 , pp. 269-277
    • Arnold, S.E.1    Franz, B.R.2    Trojanowski, J.Q.3    Moberg, P.J.4    Gur, R.E.5
  • 3
    • 32844463928 scopus 로고    scopus 로고
    • The role of cytokines in mediating effects of prenatal infection on the fetus: implications for schizophrenia
    • Ashdown H., Dumont Y., Ng M., Poole S., Boksa P., Luheshi G.N. The role of cytokines in mediating effects of prenatal infection on the fetus: implications for schizophrenia. Mol Psychiatry 2006, 11:47-55.
    • (2006) Mol Psychiatry , vol.11 , pp. 47-55
    • Ashdown, H.1    Dumont, Y.2    Ng, M.3    Poole, S.4    Boksa, P.5    Luheshi, G.N.6
  • 4
    • 0032771175 scopus 로고    scopus 로고
    • Cytokine and S100B levels in paediatric patients undergoing corrective cardiac surgery with or without total circulatory arrest
    • Ashraf S., Bhattacharya K., Tian Y., Watterson K. Cytokine and S100B levels in paediatric patients undergoing corrective cardiac surgery with or without total circulatory arrest. Eur J Cardiothorac Surg 1999, 16:32-37.
    • (1999) Eur J Cardiothorac Surg , vol.16 , pp. 32-37
    • Ashraf, S.1    Bhattacharya, K.2    Tian, Y.3    Watterson, K.4
  • 5
    • 58149385775 scopus 로고    scopus 로고
    • Interleukin-6 mediates the increase in NADPH-oxidase in the ketamine model of schizophrenia
    • Behrens M.M., Ali S.S., Dugan L.L. Interleukin-6 mediates the increase in NADPH-oxidase in the ketamine model of schizophrenia. J Neurosci 2008, 28:13957-13966.
    • (2008) J Neurosci , vol.28 , pp. 13957-13966
    • Behrens, M.M.1    Ali, S.S.2    Dugan, L.L.3
  • 7
    • 0032253227 scopus 로고    scopus 로고
    • Reduced glutathione and glutathione disulfide
    • Browne R.W., Armstrong D. Reduced glutathione and glutathione disulfide. Methods Mol Biol 1998, 108:347-352.
    • (1998) Methods Mol Biol , vol.108 , pp. 347-352
    • Browne, R.W.1    Armstrong, D.2
  • 8
    • 26444602562 scopus 로고    scopus 로고
    • Protein S100B release from rat brain slices during and after ischemia: comparison with lactate dehydrogenase leakage
    • Buyukuysal R.L. Protein S100B release from rat brain slices during and after ischemia: comparison with lactate dehydrogenase leakage. Neurochem Int 2005, 47:580-588.
    • (2005) Neurochem Int , vol.47 , pp. 580-588
    • Buyukuysal, R.L.1
  • 9
    • 0035878138 scopus 로고    scopus 로고
    • A quantitative immunohistochemical study of astrocytes in the entorhinal cortex in schizophrenia, bipolar disorder and major depression: absence of significant astrocytosis
    • Damadzic R., Bigelow L.B., Krimer L.S., Goldenson D.A., Saunders R.C., Kleinman J.E., et al. A quantitative immunohistochemical study of astrocytes in the entorhinal cortex in schizophrenia, bipolar disorder and major depression: absence of significant astrocytosis. Brain Res Bull 2001, 55:611-618.
    • (2001) Brain Res Bull , vol.55 , pp. 611-618
    • Damadzic, R.1    Bigelow, L.B.2    Krimer, L.S.3    Goldenson, D.A.4    Saunders, R.C.5    Kleinman, J.E.6
  • 10
    • 58149250311 scopus 로고    scopus 로고
    • S100B secretion is stimulated by IL-1beta in glial cultures and hippocampal slices of rats: likely involvement of MAPK pathway
    • de Souza D.F., Leite M.C., Quincozes-Santos A., Nardin P., Tortorelli L.S., Rigo M.M., et al. S100B secretion is stimulated by IL-1beta in glial cultures and hippocampal slices of rats: likely involvement of MAPK pathway. J Neuroimmunol 2009, 206:52-57.
    • (2009) J Neuroimmunol , vol.206 , pp. 52-57
    • de Souza, D.F.1    Leite, M.C.2    Quincozes-Santos, A.3    Nardin, P.4    Tortorelli, L.S.5    Rigo, M.M.6
  • 11
    • 0034995073 scopus 로고    scopus 로고
    • S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles
    • Donato R. S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. Int J Biochem Cell Biol 2001, 33:637-668.
    • (2001) Int J Biochem Cell Biol , vol.33 , pp. 637-668
    • Donato, R.1
  • 13
    • 33750463062 scopus 로고    scopus 로고
    • TNF alpha affects the expression of GFAP and S100B: implications for Alzheimer's disease
    • Edwards M.M., Robinson S.R. TNF alpha affects the expression of GFAP and S100B: implications for Alzheimer's disease. J Neural Transm 2006, 113:1709-1715.
    • (2006) J Neural Transm , vol.113 , pp. 1709-1715
    • Edwards, M.M.1    Robinson, S.R.2
  • 14
    • 65349191920 scopus 로고    scopus 로고
    • The neurodevelopmental hypothesis of schizophrenia, revisited
    • Fatemi S.H., Folsom T.D. The neurodevelopmental hypothesis of schizophrenia, revisited. Schizophr Bull 2009, 35:528-548.
    • (2009) Schizophr Bull , vol.35 , pp. 528-548
    • Fatemi, S.H.1    Folsom, T.D.2
  • 15
    • 0042427478 scopus 로고    scopus 로고
    • Oxidative stress stimulates multiple MAPK signalling pathways and phosphorylation of the small HSP27 in the perfused amphibian heart
    • Gaitanaki C., Konstantina S., Chrysa S., Beis I. Oxidative stress stimulates multiple MAPK signalling pathways and phosphorylation of the small HSP27 in the perfused amphibian heart. J Exp Biol 2003, 206:2759-2769.
    • (2003) J Exp Biol , vol.206 , pp. 2759-2769
    • Gaitanaki, C.1    Konstantina, S.2    Chrysa, S.3    Beis, I.4
  • 16
    • 80155165242 scopus 로고    scopus 로고
    • Origin and consequences of brain toll-like receptor 4 pathway stimulation in an experimental model of depression
    • Garate I., Garcia-Bueno B., Madrigal J.L., Bravo L., Berrocoso E., Caso J.R., et al. Origin and consequences of brain toll-like receptor 4 pathway stimulation in an experimental model of depression. J Neuroinflammation 2011, 8:151.
    • (2011) J Neuroinflammation , vol.8 , pp. 151
    • Garate, I.1    Garcia-Bueno, B.2    Madrigal, J.L.3    Bravo, L.4    Berrocoso, E.5    Caso, J.R.6
  • 18
    • 44949258862 scopus 로고    scopus 로고
    • Biological and methodological features of the measurement of S100B, a putative marker of brain injury
    • Goncalves C.A., Leite M.C., Nardin P. Biological and methodological features of the measurement of S100B, a putative marker of brain injury. Clin Biochem 2008, 41:755-763.
    • (2008) Clin Biochem , vol.41 , pp. 755-763
    • Goncalves, C.A.1    Leite, M.C.2    Nardin, P.3
  • 19
    • 77955975004 scopus 로고    scopus 로고
    • Adipocytes as an important source of serum S100B and possible roles of this protein in adipose tissue
    • Goncalves C.A., Leite M.C., Guerra M.C. Adipocytes as an important source of serum S100B and possible roles of this protein in adipose tissue. Cardiovasc Psychiatry Neurol 2010, 2010:790431.
    • (2010) Cardiovasc Psychiatry Neurol , vol.2010 , pp. 790431
    • Goncalves, C.A.1    Leite, M.C.2    Guerra, M.C.3
  • 20
    • 0031983986 scopus 로고    scopus 로고
    • Glial-neuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression
    • Griffin W.S., Sheng J.G., Royston M.C., Gentleman S.M., McKenzie J.E., Graham D.I., et al. Glial-neuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression. Brain Pathol 1998, 8:65-72.
    • (1998) Brain Pathol , vol.8 , pp. 65-72
    • Griffin, W.S.1    Sheng, J.G.2    Royston, M.C.3    Gentleman, S.M.4    McKenzie, J.E.5    Graham, D.I.6
  • 21
    • 80053484106 scopus 로고    scopus 로고
    • Lipopolysaccharide modulates astrocytic S100B secretion: a study in cerebrospinal fluid and astrocyte cultures from rats
    • Guerra M.C., Tortorelli L.S., Galland F., Da Re C., Negri E., Engelke D.S., et al. Lipopolysaccharide modulates astrocytic S100B secretion: a study in cerebrospinal fluid and astrocyte cultures from rats. J Neuroinflammation 2011, 8:128.
    • (2011) J Neuroinflammation , vol.8 , pp. 128
    • Guerra, M.C.1    Tortorelli, L.S.2    Galland, F.3    Da Re, C.4    Negri, E.5    Engelke, D.S.6
  • 22
    • 0029671449 scopus 로고    scopus 로고
    • S100 beta stimulates inducible nitric oxide synthase activity and mRNA levels in rat cortical astrocytes
    • Hu J., Castets F., Guevara J.L., Van Eldik L.J. S100 beta stimulates inducible nitric oxide synthase activity and mRNA levels in rat cortical astrocytes. J Biol Chem 1996, 271:2543-2547.
    • (1996) J Biol Chem , vol.271 , pp. 2543-2547
    • Hu, J.1    Castets, F.2    Guevara, J.L.3    Van Eldik, L.J.4
  • 23
    • 61449125226 scopus 로고    scopus 로고
    • Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer
    • Khansari N., Shakiba Y., Mahmoudi M. Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer. Recent Patents Inflamm Allergy Drug Discov 2009, 3:73-80.
    • (2009) Recent Patents Inflamm Allergy Drug Discov , vol.3 , pp. 73-80
    • Khansari, N.1    Shakiba, Y.2    Mahmoudi, M.3
  • 24
    • 50349086333 scopus 로고    scopus 로고
    • Neuropharmacology of second-generation antipsychotic drugs: a validity of the serotonin-dopamine hypothesis
    • Kuroki T., Nagao N., Nakahara T. Neuropharmacology of second-generation antipsychotic drugs: a validity of the serotonin-dopamine hypothesis. Prog Brain Res 2008, 172:199-212.
    • (2008) Prog Brain Res , vol.172 , pp. 199-212
    • Kuroki, T.1    Nagao, N.2    Nakahara, T.3
  • 26
    • 39749090021 scopus 로고    scopus 로고
    • A simple, sensitive and widely applicable ELISA for S100B: methodological features of the measurement of this glial protein
    • Leite M.C., Galland F., Brolese G., Guerra M.C., Bortolotto J.W., Freitas R., et al. A simple, sensitive and widely applicable ELISA for S100B: methodological features of the measurement of this glial protein. J Neurosci Methods 2008, 169:93-99.
    • (2008) J Neurosci Methods , vol.169 , pp. 93-99
    • Leite, M.C.1    Galland, F.2    Brolese, G.3    Guerra, M.C.4    Bortolotto, J.W.5    Freitas, R.6
  • 27
    • 19944432629 scopus 로고    scopus 로고
    • SNPs and haplotypes in the S100B gene reveal association with schizophrenia
    • Liu J., Shi Y., Tang J., Guo T., Li X., Yang Y., et al. SNPs and haplotypes in the S100B gene reveal association with schizophrenia. Biochem Biophys Res Commun 2005, 328:335-341.
    • (2005) Biochem Biophys Res Commun , vol.328 , pp. 335-341
    • Liu, J.1    Shi, Y.2    Tang, J.3    Guo, T.4    Li, X.5    Yang, Y.6
  • 31
    • 80052853015 scopus 로고    scopus 로고
    • Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects
    • Miller B.J., Buckley P., Seabolt W., Mellor A., Kirkpatrick B. Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects. Biol Psychiatry 2011, 70:663-671.
    • (2011) Biol Psychiatry , vol.70 , pp. 663-671
    • Miller, B.J.1    Buckley, P.2    Seabolt, W.3    Mellor, A.4    Kirkpatrick, B.5
  • 32
    • 65649134782 scopus 로고    scopus 로고
    • Cytokines and schizophrenia: microglia hypothesis of schizophrenia
    • Monji A., Kato T., Kanba S. Cytokines and schizophrenia: microglia hypothesis of schizophrenia. Psychiatry Clin Neurosci 2009, 63:257-265.
    • (2009) Psychiatry Clin Neurosci , vol.63 , pp. 257-265
    • Monji, A.1    Kato, T.2    Kanba, S.3
  • 34
    • 0017613512 scopus 로고
    • A simplification of the protein assay method of Lowry et al. which is more generally applicable
    • Peterson G.L. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal Biochem 1977, 83:346-356.
    • (1977) Anal Biochem , vol.83 , pp. 346-356
    • Peterson, G.L.1
  • 35
    • 33846847640 scopus 로고    scopus 로고
    • Long-term antipsychotic treatments and crossover studies in rats: differential effects of typical and atypical agents on the expression of antioxidant enzymes and membrane lipid peroxidation in rat brain
    • Pillai A., Parikh V., Terry A.V., Mahadik S.P. Long-term antipsychotic treatments and crossover studies in rats: differential effects of typical and atypical agents on the expression of antioxidant enzymes and membrane lipid peroxidation in rat brain. J Psychiatr Res 2007, 41:372-386.
    • (2007) J Psychiatr Res , vol.41 , pp. 372-386
    • Pillai, A.1    Parikh, V.2    Terry, A.V.3    Mahadik, S.P.4
  • 36
    • 0035000152 scopus 로고    scopus 로고
    • S-100 beta reflects the extent of injury and outcome, whereas neuronal specific enolase is a better indicator of neuroinflammation in patients with severe traumatic brain injury
    • Pleines U.E., Morganti-Kossmann M.C., Rancan M., Joller H., Trentz O., Kossmann T. S-100 beta reflects the extent of injury and outcome, whereas neuronal specific enolase is a better indicator of neuroinflammation in patients with severe traumatic brain injury. J Neurotrauma 2001, 18:491-498.
    • (2001) J Neurotrauma , vol.18 , pp. 491-498
    • Pleines, U.E.1    Morganti-Kossmann, M.C.2    Rancan, M.3    Joller, H.4    Trentz, O.5    Kossmann, T.6
  • 38
    • 40949107708 scopus 로고    scopus 로고
    • Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review
    • Potvin S., Stip E., Sepehry A.A., Gendron A., Bah R., Kouassi E. Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review. Biol Psychiatry 2008, 63:801-808.
    • (2008) Biol Psychiatry , vol.63 , pp. 801-808
    • Potvin, S.1    Stip, E.2    Sepehry, A.A.3    Gendron, A.4    Bah, R.5    Kouassi, E.6
  • 41
    • 6044238142 scopus 로고    scopus 로고
    • Glial cell dysfunction in schizophrenia indicated by increased S100B in the CSF
    • Rothermundt M., Falkai P., Ponath G., Abel S., Burkle H., Diedrich M., et al. Glial cell dysfunction in schizophrenia indicated by increased S100B in the CSF. Mol Psychiatry 2004, 9:897-899.
    • (2004) Mol Psychiatry , vol.9 , pp. 897-899
    • Rothermundt, M.1    Falkai, P.2    Ponath, G.3    Abel, S.4    Burkle, H.5    Diedrich, M.6
  • 42
    • 34548044662 scopus 로고    scopus 로고
    • S100B modulates IL-6 release and cytotoxicity from hypothermic brain cells and inhibits hypothermia-induced axonal outgrowth
    • Schmitt K.R., Kern C., Lange P.E., Berger F., Abdul-Khaliq H., Hendrix S. S100B modulates IL-6 release and cytotoxicity from hypothermic brain cells and inhibits hypothermia-induced axonal outgrowth. Neurosci Res 2007, 59:68-73.
    • (2007) Neurosci Res , vol.59 , pp. 68-73
    • Schmitt, K.R.1    Kern, C.2    Lange, P.E.3    Berger, F.4    Abdul-Khaliq, H.5    Hendrix, S.6
  • 43
    • 60549102293 scopus 로고    scopus 로고
    • Elevated serum levels of the glial marker protein S100B are not specific for schizophrenia or mood disorders
    • Schroeter M.L., Steiner J. Elevated serum levels of the glial marker protein S100B are not specific for schizophrenia or mood disorders. Mol Psychiatry 2009, 14:235-237.
    • (2009) Mol Psychiatry , vol.14 , pp. 235-237
    • Schroeter, M.L.1    Steiner, J.2
  • 45
    • 78751501237 scopus 로고    scopus 로고
    • Risperidone-induced inactivation and clozapine-induced reactivation of rat cortical astrocyte 5-hydroxytryptamine (7) receptors: evidence for in situ G protein-coupled receptor homodimer protomer cross-talk
    • Smith C., Toohey N., Knight J.A., Klein M.T., Teitler M. Risperidone-induced inactivation and clozapine-induced reactivation of rat cortical astrocyte 5-hydroxytryptamine (7) receptors: evidence for in situ G protein-coupled receptor homodimer protomer cross-talk. Mol Pharmacol 2011, 79:318-325.
    • (2011) Mol Pharmacol , vol.79 , pp. 318-325
    • Smith, C.1    Toohey, N.2    Knight, J.A.3    Klein, M.T.4    Teitler, M.5
  • 46
    • 33750429912 scopus 로고    scopus 로고
    • Increased cerebrospinal fluid and serum levels of S100B in first-onset schizophrenia are not related to a degenerative release of glial fibrillar acidic protein, myelin basic protein and neurone-specific enolase from glia or neurones
    • Steiner J., Bielau H., Bernstein H.G., Bogerts B., Wunderlich M.T. Increased cerebrospinal fluid and serum levels of S100B in first-onset schizophrenia are not related to a degenerative release of glial fibrillar acidic protein, myelin basic protein and neurone-specific enolase from glia or neurones. J Neurol Neurosurg Psychiatry 2006, 77:1284-1287.
    • (2006) J Neurol Neurosurg Psychiatry , vol.77 , pp. 1284-1287
    • Steiner, J.1    Bielau, H.2    Bernstein, H.G.3    Bogerts, B.4    Wunderlich, M.T.5
  • 47
    • 46549086821 scopus 로고    scopus 로고
    • S100B is expressed in, and released from, OLN-93 oligodendrocytes: influence of serum and glucose deprivation
    • Steiner J., Bernstein H.G., Bogerts B., Gos T., Richter-Landsberg C., Wunderlich M.T., et al. S100B is expressed in, and released from, OLN-93 oligodendrocytes: influence of serum and glucose deprivation. Neuroscience 2008, 154:496-503.
    • (2008) Neuroscience , vol.154 , pp. 496-503
    • Steiner, J.1    Bernstein, H.G.2    Bogerts, B.3    Gos, T.4    Richter-Landsberg, C.5    Wunderlich, M.T.6
  • 48
    • 67349266228 scopus 로고    scopus 로고
    • A new pathophysiological aspect of S100B in schizophrenia: potential regulation of S100B by its scavenger soluble RAGE
    • Steiner J., Walter M., Wunderlich M.T., Bernstein H.G., Panteli B., Brauner M., et al. A new pathophysiological aspect of S100B in schizophrenia: potential regulation of S100B by its scavenger soluble RAGE. Biol Psychiatry 2009, 65:1107-1110.
    • (2009) Biol Psychiatry , vol.65 , pp. 1107-1110
    • Steiner, J.1    Walter, M.2    Wunderlich, M.T.3    Bernstein, H.G.4    Panteli, B.5    Brauner, M.6
  • 51
    • 2442490082 scopus 로고    scopus 로고
    • CAMP-induced astrocytic differentiation of C6 glioma cells is mediated by autocrine interleukin-6
    • Takanaga H., Yoshitake T., Hara S., Yamasaki C., Kunimoto M. cAMP-induced astrocytic differentiation of C6 glioma cells is mediated by autocrine interleukin-6. J Biol Chem 2004, 279:15441-15447.
    • (2004) J Biol Chem , vol.279 , pp. 15441-15447
    • Takanaga, H.1    Yoshitake, T.2    Hara, S.3    Yamasaki, C.4    Kunimoto, M.5
  • 52
    • 75949099783 scopus 로고    scopus 로고
    • Inflammation in neuropsychiatric disease
    • Tansey M.G. Inflammation in neuropsychiatric disease. Neurobiol Dis 2010, 37:491-492.
    • (2010) Neurobiol Dis , vol.37 , pp. 491-492
    • Tansey, M.G.1
  • 54
    • 0032400997 scopus 로고    scopus 로고
    • Regulation of NF-kappa B, AP-1, NFAT, and STAT1 nuclear import in T lymphocytes by noninvasive delivery of peptide carrying the nuclear localization sequence of NF-kappa B p50
    • Torgerson T.R., Colosia A.D., Donahue J.P., Lin Y.Z., Hawiger J. Regulation of NF-kappa B, AP-1, NFAT, and STAT1 nuclear import in T lymphocytes by noninvasive delivery of peptide carrying the nuclear localization sequence of NF-kappa B p50. J Immunol 1998, 161:6084-6092.
    • (1998) J Immunol , vol.161 , pp. 6084-6092
    • Torgerson, T.R.1    Colosia, A.D.2    Donahue, J.P.3    Lin, Y.Z.4    Hawiger, J.5
  • 55
    • 33746327778 scopus 로고    scopus 로고
    • High glutamate decreases S100B secretion by a mechanism dependent on the glutamate transporter
    • Tramontina F., Leite M.C., Goncalves D., Tramontina A.C., Souza D.F., Frizzo J.K., et al. High glutamate decreases S100B secretion by a mechanism dependent on the glutamate transporter. Neurochem Res 2006, 31:815-820.
    • (2006) Neurochem Res , vol.31 , pp. 815-820
    • Tramontina, F.1    Leite, M.C.2    Goncalves, D.3    Tramontina, A.C.4    Souza, D.F.5    Frizzo, J.K.6
  • 57
    • 77952569813 scopus 로고    scopus 로고
    • Cytokine hypothesis of schizophrenia pathogenesis: evidence from human studies and animal models
    • Watanabe Y., Someya T., Nawa H. Cytokine hypothesis of schizophrenia pathogenesis: evidence from human studies and animal models. Psychiatry Clin Neurosci 2010, 64:217-230.
    • (2010) Psychiatry Clin Neurosci , vol.64 , pp. 217-230
    • Watanabe, Y.1    Someya, T.2    Nawa, H.3
  • 58
    • 77956302879 scopus 로고    scopus 로고
    • Inflammation in neurological disorders: a help or a hindrance
    • Wee Yong V. Inflammation in neurological disorders: a help or a hindrance. Neuroscientist 2010, 16:408-420.
    • (2010) Neuroscientist , vol.16 , pp. 408-420
    • Wee Yong, V.1
  • 59
    • 0036775329 scopus 로고    scopus 로고
    • Elevated interleukin-2, interleukin-6 and interleukin-8 serum levels in neuroleptic-free schizophrenia: association with psychopathology
    • Zhang X.Y., Zhou D.F., Zhang P.Y., Wu G.Y., Cao L.Y., Shen Y.C. Elevated interleukin-2, interleukin-6 and interleukin-8 serum levels in neuroleptic-free schizophrenia: association with psychopathology. Schizophr Res 2002, 57:247-258.
    • (2002) Schizophr Res , vol.57 , pp. 247-258
    • Zhang, X.Y.1    Zhou, D.F.2    Zhang, P.Y.3    Wu, G.Y.4    Cao, L.Y.5    Shen, Y.C.6


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