Cutting edge: Ly9 (CD229), a SLAM family receptor, negatively regulates the development of thymic innate memory-like CD8+ T and invariant NKT cells

Journal of Immunology

Volumn 190, Issue 1, 2013, Pages 21-25

  Sintes, Jordi ^a,b   Cuenca, Marta ^a,b   Romero, Xavier ^a,b   Bastos, Ricardo ^a,b   Terhorst, Cox ^c   Angulo, Ana ^a,b   Engel, Pablo ^a,b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; CD150 ANTIGEN; CELL SURFACE RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ARTICLE; CD8+ T LYMPHOCYTE; FEMALE; GENE EXPRESSION PROFILING; INNATE IMMUNITY; LYMPHOCYTE ACTIVATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; THYMUS; UPREGULATION; WILD TYPE;

ANIMALS; ANTIGENS, CD; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; DOWN-REGULATION; FEMALE; GROWTH INHIBITORS; IMMUNITY, INNATE; IMMUNOLOGIC MEMORY; MICE; MICE, 129 STRAIN; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NATURAL KILLER T-CELLS; RECEPTORS, CELL SURFACE; THYMUS GLAND;

EID: 84871842995     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202435     Document Type: Article

References (17)

1. Lee, Y. J., S. C. Jameson, and K. A. Hogquist. 2011. Alternative memory in the CD8 T cell lineage. Trends Immunol. 32: 50-56.
2. + T cells. Nat. Immunol. 11: 709-716.
3. + T cells in BALB/c mice by regulating IL-4-generating invariant natural killer T cells. J. Exp. Med. 208: 1093-1103.
4. Alonzo, E. S., and D. B. Sant'Angelo. 2011. Development of PLZF-expressing innate T cells. Curr. Opin. Immunol. 23: 220-227.
5. Griewank, K., C. Borowski, S. Rietdijk, N. Wang, A. Julien, D. G. Wei, A. A. Mamchak, C. Terhorst, and A. Bendelac. 2007. Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development. Immunity 27: 751-762. (Pubitemid 350102258)
6. Horai, R., K. L. Mueller, R. A. Handon, J. L. Cannons, S. M. Anderson, M. R. Kirby, and P. L. Schwartzberg. 2007. Requirements for selection of conventional and innate T lymphocyte lineages. Immunity 27: 775-785. (Pubitemid 350102265)
7. Kageyama, R., J. L. Cannons, F. Zhao, I. Yusuf, C. Lao, M. Locci, P. L. Schwartzberg, and S. Crotty. 2012. The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development. Immunity 36: 986-1002.
8. + T cells with innate lymphocyte characteristics. Immunity 33: 203-215.
9. Romero, X., N. Zapater, M. Calvo, S. G. Kalko, M. A. de la Fuente, V. Tovar, C. Ockeloen, P. Pizcueta, and P. Engel. 2005. CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. J. Immunol. 174: 7033-7042. (Pubitemid 40705668)
10. Sintes, J., M. Vidal-Laliena, X. Romero, V. Tovar, and P. Engel. 2007. Characterization of mouse CD229 (Ly9), a leukocyte cell surface molecule of the CD150 (SLAM) family. Tissue Antigens 70: 355-362. (Pubitemid 47537393)
11. Graham, D. B., M. P. Bell, M. M. McCausland, C. J. Huntoon, J. van Deursen, W. A. Faubion, S. Crotty, and D. J. McKean. 2006. Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice. J. Immunol. 176: 291-300. (Pubitemid 43023274)
12. Tyznik, A. J., E. Tupin, N. A. Nagarajan, M. J. Her, C. A. Benedict, and M. Kronenberg. 2008. Cutting edge: the mechanism of invariant NKT cell responses to viral danger signals. J. Immunol. 181: 4452-4456.
13. Price, P., S. D. Olver, A. E. Gibbons, H. K. Teo, and G. R. Shellam. 1993. Characterization of thymic involution induced by murine cytomegalovirus infection. Immunol. Cell Biol. 71: 155-165. (Pubitemid 23171479)
14. Weinreich, M. A., K. Takada, C. Skon, S. L. Reiner, S. C. Jameson, and K. A. Hogquist. 2009. KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors. Immunity 31: 122-130.
15. Drennan, M. B., A. S. Franki, P. Dewint, K. Van Beneden, S. Seeuws, S. A. van de Pavert, E. C. Reilly, G. Verbruggen, T. E. Lane, R. E. Mebius, et al. 2009. Cutting edge: the chemokine receptor CXCR3 retains invariant NK T cells in the thymus. J. Immunol. 183: 2213-2216.
16. Miyazaki, M., R. R. Rivera, K. Miyazaki, Y. C. Lin, Y. Agata, and C. Murre. 2011. The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells. Nat. Immunol. 12: 992-1001.
17. Martín, M., J. M. Del Valle, I. Saborit, and P. Engel. 2005. Identification of Grb2 as a novel binding partner of the signaling lymphocytic activation moleculeassociated protein binding receptor CD229. J. Immunol. 174: 5977-5986. (Pubitemid 40663784)