메뉴 건너뛰기




Volumn 53, Issue , 2014, Pages 277-298

Antiangiogenic approaches to renal cell carcinoma assays for inhibitors and clinical trials

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOPOIETIN 2; THROMBOSPONDIN 1; VASCULOTROPIN;

EID: 84871820343     PISSN: 15431894     EISSN: 19406037     Source Type: Book Series    
DOI: None     Document Type: Article
Times cited : (1)

References (118)
  • 1
    • 0029837761 scopus 로고    scopus 로고
    • How tumors become angiogenic. Adv
    • Bouck, N., Stellmach, V., and Hsu, S. C. (1996) How tumors become angiogenic. Adv. Cancer Res. 69, 135-174
    • (1996) Cancer Res , vol.69 , pp. 135-174
    • Bouck, N.1    Stellmach, V.2    Hsu, S.C.3
  • 2
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat
    • Folkman, J. (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1(1), 27-31
    • (1995) Med , vol.1 , Issue.1 , pp. 27-31
    • Folkman, J.1
  • 3
    • 0001830867 scopus 로고
    • Mendelson, J., Howley, P. M., Israel, M. A., Liotta, L. A., eds.), W.B. Saunders, Philadelphia
    • Folkman, J. (1995) Tumor Angiogenesis, in Tumor Angiogenesis (Mendelson, J., Howley, P. M., Israel, M. A., Liotta, L. A., eds.), W.B. Saunders, Philadelphia, pp. 206-232
    • (1995) Tumor Angiogenesis, in Tumor Angiogenesis , pp. 206-232
    • Folkman, J.1
  • 4
    • 0029686918 scopus 로고    scopus 로고
    • Tumor angiogenesis and the role of vascular cell integrin? —vĈ3
    • Varner, J. A. and Cheresh, D. A. (1996) Tumor angiogenesis and the role of vascular cell integrin —vĈ3.3. Important Adv. Oncol. 69-87
    • (1996) Important Adv. Oncol , pp. 69-87
    • Varner, J.A.1    Cheresh, D.A.2
  • 5
    • 0033597718 scopus 로고    scopus 로고
    • Targeted deficiency or cytosolic truncation of the VEcadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis
    • Carmeliet, P., Lampugnani, M. G., Moons, L., Breviario, F., Compernolle, V., Bono, F., et al. (1999) Targeted deficiency or cytosolic truncation of the VEcadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis. Cell 98 (2), 147-157
    • (1999) Cell , vol.98 , Issue.2 , pp. 147-157
    • Carmeliet, P.1    Lampugnani, M.G.2    Moons, L.3    Breviario, F.4    Compernolle, V.5    Bono, F.6
  • 6
    • 0028865183 scopus 로고
    • The pathophysiology of angiogenesis
    • Polverini, P. J. (1995) The pathophysiology of angiogenesis. Crit. Rev. Oral Biol. Med. 6(3), 230-247
    • (1995) Crit. Rev. Oral Biol. Med , vol.6 , Issue.3 , pp. 230-247
    • Polverini, P.J.1
  • 7
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan, D. and Folkman, J. (1996) Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86(3), 353-364
    • (1996) Cell , vol.86 , Issue.3 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 9
    • 0030500444 scopus 로고    scopus 로고
    • Vascular endothelial growth factor
    • Ferrara, N. (1996) Vascular endothelial growth factor. Eur. J. Cancer 32A(14), 2413-2422
    • (1996) Eur. J. Cancer , vol.32A , Issue.14 , pp. 2413-2422
    • Ferrara, N.1
  • 10
    • 0030851764 scopus 로고    scopus 로고
    • Signaling vascular morphogenesis and maintenance
    • Hanahan, D. (1997) Signaling vascular morphogenesis and maintenance. Science 277(5322), 48-50
    • (1997) Science , vol.277 , Issue.5322 , pp. 48-50
    • Hanahan, D.1
  • 11
    • 15144358851 scopus 로고    scopus 로고
    • Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
    • Maisonpierre, P. C., Suri, C., Jones, P. F., Bartunkova, S., Wiegand, S. J., Radziejewski, C., et al. (1997) Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277(5322), 55-60
    • (1997) Science , vol.277 , Issue.5322 , pp. 55-60
    • Maisonpierre, P.C.1    Suri, C.2    Jones, P.F.3    Bartunkova, S.4    Wiegand, S.J.5    Radziejewski, C.6
  • 12
    • 0030480322 scopus 로고    scopus 로고
    • Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
    • Suri, C., Jones, P. F., Patan, S., Bartunkova, S., Maisonpierre, P. C., Davis, S., et al. (1996) Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87(7), 1171-1180
    • (1996) Cell , vol.87 , Issue.7 , pp. 1171-1180
    • Suri, C.1    Jones, P.F.2    Patan, S.3    Bartunkova, S.4    Maisonpierre, P.C.5    Davis, S.6
  • 13
    • 0023831047 scopus 로고
    • A heparin-binding angiogenic protein-basic fibroblast growth factor is stored within basement membrane
    • Folkman, J., Klagsbrun, M., Sasse, J., Wadzinski, M., Ingber, D., and Vlodavsky, I. (1988) A heparin-binding angiogenic protein-basic fibroblast growth factor is stored within basement membrane. Am. J. Pathol. 130(2), 393-400
    • (1988) Am. J. Pathol , vol.130 , Issue.2 , pp. 393-400
    • Folkman, J.1    Klagsbrun, M.2    Sasse, J.3    Wadzinski, M.4    Ingber, D.5    Vlodavsky, I.6
  • 15
    • 0030037264 scopus 로고    scopus 로고
    • Angiogenesis as an unfavorable prognostic factor in human colorectal carcinoma
    • Takebayashi, Y., Aklyama, S., Yamada, K., Akiba, S., and Aikou, T. (1996) Angiogenesis as an unfavorable prognostic factor in human colorectal carcinoma. Cancer 78(2), 226-231
    • (1996) Cancer , vol.78 , Issue.2 , pp. 226-231
    • Takebayashi, Y.1    Aklyama, S.2    Yamada, K.3    Akiba, S.4    Aikou, T.5
  • 16
    • 0030502296 scopus 로고    scopus 로고
    • Clinical significance of the determination of angiogenesis in human breast cancer: Update of the biological background and overview of the Vicenza studies
    • Gasparini, G. (1996) Clinical significance of the determination of angiogenesis in human breast cancer: update of the biological background and overview of the Vicenza studies. Eur. J. Cancer 32A(14), 2485-2493
    • (1996) Eur. J. Cancer , vol.32A , Issue.14 , pp. 2485-2493
    • Gasparini, G.1
  • 17
    • 0026083903 scopus 로고
    • Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma
    • Weidner, N., Semple, J. P., Welch, W. R., and Folkman, J. (1991) Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N. Engl. J. Med. 324(1), 1-8
    • (1991) N. Engl. J. Med , vol.324 , Issue.1 , pp. 1-8
    • Weidner, N.1    Semple, J.P.2    Welch, W.R.3    Folkman, J.4
  • 18
    • 0028203659 scopus 로고
    • Clinical prognostic significance of tumour angiogenesis
    • Craft, P. S. and Harris, A. L. (1994) Clinical prognostic significance of tumour angiogenesis. Ann. Oncol. 5(4), 305-311
    • (1994) Ann. Oncol , vol.5 , Issue.4 , pp. 305-311
    • Craft, P.S.1    Harris, A.L.2
  • 19
    • 0023160237 scopus 로고
    • Inhibition of angiogenesis by interferons: Effects on tumor-and lymphocyte-induced vascular responses
    • Sidky, Y. A. and Borden, E. C. (1987) Inhibition of angiogenesis by interferons: effects on tumor-and lymphocyte-induced vascular responses. Cancer Res. 47(19), 5155-5161
    • (1987) Cancer Res , vol.47 , Issue.19 , pp. 5155-5161
    • Sidky, Y.A.1    Borden, E.C.2
  • 20
    • 0029562535 scopus 로고
    • Inhibition of angiogenesis by thrombospondin-2. Biochem. Biophys. Res
    • Volpert, O. V., Tolsma, S. S., Pellerin, S., Feige, J. J., Chen, H., Mosher, D. F., et al. (1995) Inhibition of angiogenesis by thrombospondin-2. Biochem. Biophys. Res. Commun. 217(1), 326-332
    • (1995) Commun , vol.217 , Issue.1 , pp. 326-332
    • Volpert, O.V.1    Tolsma, S.S.2    Pellerin, S.3    Feige, J.J.4    Chen, H.5    Mosher, D.F.6
  • 21
    • 0025147371 scopus 로고
    • A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin
    • Good, D. J., Polverini, P. J., Rastinejad, F., Le Beau, M. M., Lemons, R. S., Frazier, W. A., et al. (1990) A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc. Natl. Acad. Sci. USA, 87(17), 6624-6628
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , Issue.17 , pp. 6624-6628
    • Good, D.J.1    Polverini, P.J.2    Rastinejad, F.3    Le Beau, M.M.4    Lemons, R.S.5    Frazier, W.A.6
  • 25
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • O’Reilly, M. S., Holmgren, L., Shing, Y., Chen, C., Rosenthal, R. A., Moses, M., et al. (1994) Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79(2), 315-328
    • (1994) Cell , vol.79 , Issue.2 , pp. 315-328
    • O’reilly, M.S.1    Holmgren, L.2    Shing, Y.3    Chen, C.4    Rosenthal, R.A.5    Moses, M.6
  • 26
    • 0031469819 scopus 로고    scopus 로고
    • Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance
    • Boehm, T., Folkman, J., Browder, T., and O’Reilly, M. S. (1997) Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 390(6658), 404-407
    • (1997) Nature , vol.390 , Issue.6658 , pp. 404-407
    • Boehm, T.1    Folkman, J.2    Browder, T.3    O’reilly, M.S.4
  • 27
    • 0031454617 scopus 로고    scopus 로고
    • Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
    • O’Reilly, M. S., Boehm, T., Shing, Y., Fukai, N., Vasios, G., Lane, W. S., et al. (1997) Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 88(2), 277-285
    • (1997) Cell , vol.88 , Issue.2 , pp. 277-285
    • O’reilly, M.S.1    Boehm, T.2    Shing, Y.3    Fukai, N.4    Vasios, G.5    Lane, W.S.6
  • 28
    • 0030893967 scopus 로고    scopus 로고
    • Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity
    • Volpert, O. V., Dameron, K. M., and Bouck, N. (1997) Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity. Oncogene 14(12), 1495-1502
    • (1997) Oncogene , vol.14 , Issue.12 , pp. 1495-1502
    • Volpert, O.V.1    Dameron, K.M.2    Bouck, N.3
  • 29
    • 0032521539 scopus 로고    scopus 로고
    • Molecular mediators of angiogenesis in bladder cancer
    • Campbell, S. C., Volpert, O. V., Ivanovich, M., and Bouck, N. P. (1998) Molecular mediators of angiogenesis in bladder cancer. Cancer Res. 58(6), 1298-1304
    • (1998) Cancer Res , vol.58 , Issue.6 , pp. 1298-1304
    • Campbell, S.C.1    Volpert, O.V.2    Ivanovich, M.3    Bouck, N.P.4
  • 30
    • 0029754648 scopus 로고    scopus 로고
    • Inhibition of angiogenesis in human glioblastomas by chromosome 10 induction of thrombospondin-1
    • Hsu, S. C., Volpert, O. V., Steck, P. A., Mikkelsen, T., Polverini, P. J., Rao, S., et al. (1996) Inhibition of angiogenesis in human glioblastomas by chromosome 10 induction of thrombospondin-1. Cancer Res. 56(24), 5684-5691
    • (1996) Cancer Res , vol.56 , Issue.24 , pp. 5684-5691
    • Hsu, S.C.1    Volpert, O.V.2    Steck, P.A.3    Mikkelsen, T.4    Polverini, P.J.5    Rao, S.6
  • 31
    • 0026082066 scopus 로고
    • Potent anti-angiogenic action of AGM-1470: Comparison to the fumagillin parent. Biochem. Biophys. Res
    • Kusaka, M., Sudo, K., Fujita, T., Marui, S., Itoh, F., Ingber, D., et al. (1991) Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent. Biochem. Biophys. Res. Commun. 174(3), 1070-1076
    • (1991) Commun , vol.174 , Issue.3 , pp. 1070-1076
    • Kusaka, M.1    Sudo, K.2    Fujita, T.3    Marui, S.4    Itoh, F.5    Ingber, D.6
  • 32
    • 15644374381 scopus 로고    scopus 로고
    • Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature
    • Sills, A. K., Jr., Williams, J. I., Tyler, B. M., Epstein, D. S., Sipos, E. P., Davis, J. D., et al. (1998) Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature. Cancer Res. 58(13), 2784-2792
    • (1998) Cancer Res , vol.58 , Issue.13 , pp. 2784-2792
    • Sills, A.K.1    Williams, J.I.2    Tyler, B.M.3    Epstein, D.S.4    Sipos, E.P.5    Davis, J.D.6
  • 33
    • 84921865828 scopus 로고    scopus 로고
    • R. (1998) Contortrostatin, a snake venom disintegrin, is an inhibitor of angiogenesis
    • (Folkman, J. and Klagsbrun, M., eds.), AACR Special Conference in Cancer Research, (abstract)
    • Zhou, O., Arnold, C., and Ritter, M. R. (1998) Contortrostatin, a snake venom disintegrin, is an inhibitor of angiogenesis, in Angiogenesis and Cancer (Folkman, J. and Klagsbrun, M., eds.), AACR Special Conference in Cancer Research, (abstract) pp. B74
    • Angiogenesis and Cancer , pp. 74
    • Zhou, O.1    Arnold, C.2    Ritter, M.3
  • 34
    • 0029982831 scopus 로고    scopus 로고
    • Retinoic acid induces cells cultured from oral squamous cell carcinomas to become anti-angiogenic
    • Lingen, M. W., Polverini, P. J., and Bouck, N. P. (1996) Retinoic acid induces cells cultured from oral squamous cell carcinomas to become anti-angiogenic. Am. J. Pathol. 149(1), 247-258
    • (1996) Am. J. Pathol , vol.149 , Issue.1 , pp. 247-258
    • Lingen, M.W.1    Polverini, P.J.2    Bouck, N.P.3
  • 35
    • 0025290247 scopus 로고
    • Inhibition of angiogenesis by vitamin D3 analogues [published erratum appears in
    • 1990 Jul 17;182(3),616]. Eur. J. Pharmacol
    • Oikawa, T., Hirotani, K., Ogasawara, H., Katayama, T., Nakamura, O., Iwaguchi, T., et al. (1990) Inhibition of angiogenesis by vitamin D3 analogues [published erratum appears in Eur. J. Pharmacol. 1990 Jul 17;182(3),616]. Eur. J. Pharmacol. 178(2), 247-250
    • (1990) Eur. J. Pharmacol , vol.178 , Issue.2 , pp. 247-250
    • Oikawa, T.1    Hirotani, K.2    Ogasawara, H.3    Katayama, T.4    Nakamura, O.5    Iwaguchi, T.6
  • 37
    • 0022627338 scopus 로고
    • Tumor angiogenesis inhibition by prostaglandin synthetase inhibitors
    • Peterson, H. I. (1986) Tumor angiogenesis inhibition by prostaglandin synthetase inhibitors. Anticancer Res. 6(2), 251-253
    • (1986) Anticancer Res , vol.6 , Issue.2 , pp. 251-253
    • Peterson, H.I.1
  • 38
    • 0029916051 scopus 로고    scopus 로고
    • Captopril inhibits angiogenesis and slows the growth of experimental tumors in rats
    • Volpert, O. V., Ward, W. F., Lingen, M. W., Chesler, L., Solt, D. B., Johnson, M. D., et al. (1996) Captopril inhibits angiogenesis and slows the growth of experimental tumors in rats. J. Clin. Invest. 98(3), 671-679
    • (1996) J. Clin. Invest , vol.98 , Issue.3 , pp. 671-679
    • Volpert, O.V.1    Ward, W.F.2    Lingen, M.W.3    Chesler, L.4    Solt, D.B.5    Johnson, M.D.6
  • 40
    • 0025924722 scopus 로고
    • Angiogenesis inhibition by minocycline
    • Tamargo, R. J., Bok, R. A., and Brem, H. (1991) Angiogenesis inhibition by minocycline. Cancer Res. 51(2), 672-675
    • (1991) Cancer Res , vol.51 , Issue.2 , pp. 672-675
    • Tamargo, R.J.1    Bok, R.A.2    Brem, H.3
  • 43
    • 0028896964 scopus 로고
    • Controlled delivery of taxol from microspheres composed of a blend of ethylene-vinyl acetate copolymer and poly (d,l-lactic acid)
    • Burt, H. M., Jackson, J. K., Bains, S. K., Liggins, R. T., Oktaba, A. M., Arsenault, A. L., et al. (1995) Controlled delivery of taxol from microspheres composed of a blend of ethylene-vinyl acetate copolymer and poly (d,l-lactic acid). Cancer Lett. 88(1), 73-79
    • (1995) Cancer Lett , vol.88 , Issue.1 , pp. 73-79
    • Burt, H.M.1    Jackson, J.K.2    Bains, S.K.3    Liggins, R.T.4    Oktaba, A.M.5    Arsenault, A.L.6
  • 44
    • 0031015504 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol
    • Klauber, N., Parangi, S., Flynn, E., Hamel, E., and D’Amato, R. J. (1997) Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol. Cancer Res. 57(1), 81-86
    • (1997) Cancer Res , vol.57 , Issue.1 , pp. 81-86
    • Klauber, N.1    Parangi, S.2    Flynn, E.3    Hamel, E.4    D’amato, R.J.5
  • 45
    • 0025850290 scopus 로고
    • Antitumour effects of indomethacin alone and in combination with radiotherapy: Role of inhibition of tumour angiogenesis
    • Milas, L., Hunter, N., Furuta, Y., Nishiguchi, I., and Runkel, S. (1991) Antitumour effects of indomethacin alone and in combination with radiotherapy: role of inhibition of tumour angiogenesis. Int. J. Radiat. Biol. 60(1-2), 65-70
    • (1991) Int. J. Radiat. Biol , vol.60 , Issue.1-2 , pp. 65-70
    • Milas, L.1    Hunter, N.2    Furuta, Y.3    Nishiguchi, I.4    Runkel, S.5
  • 46
    • 0015743475 scopus 로고
    • Proceedings: Arteriorgraphy in the diagnosis and staging of hypernephromas
    • Lang, E. K. (1973) Proceedings: arteriorgraphy in the diagnosis and staging of hypernephromas. Cancer 32(5), 1043-1052
    • (1973) Cancer , vol.32 , Issue.5 , pp. 1043-1052
    • Lang, E.K.1
  • 47
    • 0029328276 scopus 로고
    • Prognostic significance of microvessel count in low stage renal cell carcinoma
    • Yoshino, S., Kato, M., and Okada, K. (1995) Prognostic significance of microvessel count in low stage renal cell carcinoma. Int. J. Urol. 2(3), 156-160
    • (1995) Int. J. Urol , vol.2 , Issue.3 , pp. 156-160
    • Yoshino, S.1    Kato, M.2    Okada, K.3
  • 48
    • 0031799337 scopus 로고    scopus 로고
    • Clinical significance of tumor angiogenesis in patients with localized renal cell carcinoma
    • Nativ, O., Sabo, E., Reiss, A., Wald, M., Madjar, S., and Moskovitz, B. (1998) Clinical significance of tumor angiogenesis in patients with localized renal cell carcinoma. Urology 51(5), 693-696
    • (1998) Urology , vol.51 , Issue.5 , pp. 693-696
    • Nativ, O.1    Sabo, E.2    Reiss, A.3    Wald, M.4    Madjar, S.5    Moskovitz, B.6
  • 49
    • 0031398915 scopus 로고    scopus 로고
    • Prognostic significance of microscopic vascularity for clear cell renal cell carcinoma
    • Delahunt, B., Bethwaite, P. B., and Thornton, A. (1997) Prognostic significance of microscopic vascularity for clear cell renal cell carcinoma. Br. J. Urol. 80(3), 401-404
    • (1997) Br. J. Urol , vol.80 , Issue.3 , pp. 401-404
    • Delahunt, B.1    Bethwaite, P.B.2    Thornton, A.3
  • 50
    • 0030695994 scopus 로고    scopus 로고
    • Appraisal of intratumoral microvessel density, MIB-1 score, DNA content, and p53 protein expression as prognostic indicators in patients with locally confined renal cell carcinoma
    • Gelb, A. B., Sudilovsky, D., Wu, C. D., Weiss, L. M., and Medeiros, L. J. (1997) Appraisal of intratumoral microvessel density, MIB-1 score, DNA content, and p53 protein expression as prognostic indicators in patients with locally confined renal cell carcinoma. Cancer 80(9), 1768-1775
    • (1997) Cancer , vol.80 , Issue.9 , pp. 1768-1775
    • Gelb, A.B.1    Sudilovsky, D.2    Wu, C.D.3    Weiss, L.M.4    Medeiros, L.J.5
  • 51
    • 0030512898 scopus 로고    scopus 로고
    • Quantification of angiogenesis in solid human tumours: An international consensus on the methodology and criteria of evaluation
    • Vermeulen, P. B., Gasparini, G., Fox, S. B., Toi, M., Martin, L., McCulloch, P., et al. (1996) Quantification of angiogenesis in solid human tumours: an international consensus on the methodology and criteria of evaluation. Eur. J. Cancer 32A(14), 2474-2484
    • (1996) Eur. J. Cancer , vol.32A , Issue.14 , pp. 2474-2484
    • Vermeulen, P.B.1    Gasparini, G.2    Fox, S.B.3    Toi, M.4    Martin, L.5    McCulloch, P.6
  • 52
    • 0029127219 scopus 로고
    • Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res
    • Weidner, N. (1995) Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res. Treat. 36(2), 169-180
    • (1995) Treat , vol.36 , Issue.2 , pp. 169-180
    • Weidner, N.1
  • 53
    • 0029943907 scopus 로고    scopus 로고
    • Introduction of basic fibroblast growth factor gene into mouse renal cell carcinoma cell line enhances its metastatic potential
    • Miyake, H., Hara, I., Yoshimura, K., Eto, H., Arakawa, S., Wada, S., et al. (1996) Introduction of basic fibroblast growth factor gene into mouse renal cell carcinoma cell line enhances its metastatic potential. Cancer Res. 56 (10), 2440-2445
    • (1996) Cancer Res , vol.56 , Issue.10 , pp. 2440-2445
    • Miyake, H.1    Hara, I.2    Yoshimura, K.3    Eto, H.4    Arakawa, S.5    Wada, S.6
  • 54
  • 55
    • 0029681849 scopus 로고    scopus 로고
    • Injection of complementary DNA encoding interleukin-12 inhibits tumor establishment at a distant site in a murine renal carcinoma model
    • Tan, J., Newton, C. A., Djeu, J. Y., Gutsch, D. E., Chang, A. E., Yang, N. S., et al. (1996) Injection of complementary DNA encoding interleukin-12 inhibits tumor establishment at a distant site in a murine renal carcinoma model. Cancer Res. 56(15), 3399-3403
    • (1996) Cancer Res , vol.56 , Issue.15 , pp. 3399-3403
    • Tan, J.1    Newton, C.A.2    Djeu, J.Y.3    Gutsch, D.E.4    Chang, A.E.5    Yang, N.S.6
  • 56
    • 0029870719 scopus 로고    scopus 로고
    • Antitumor effects of angiogenesis inhibitor 0-(chloroacetyl-carbamoyl) fumagillol (TNP-470) against murine renal cell carcinoma
    • Fujioka, T., Hasegawa, M., Ogiu, K., Matsushita, Y., Sato, M., and Kubo, T. (1996) Antitumor effects of angiogenesis inhibitor 0-(chloroacetyl-carbamoyl) fumagillol (TNP-470) against murine renal cell carcinoma. J. Urol. 155(5), 1775-1778
    • (1996) J. Urol , vol.155 , Issue.5 , pp. 1775-1778
    • Fujioka, T.1    Hasegawa, M.2    Ogiu, K.3    Matsushita, Y.4    Sato, M.5    Kubo, T.6
  • 57
    • 0027988397 scopus 로고
    • Antitumour effect of a synthetic analogue of fumagillin on murine renal carcinoma
    • Morita, T., Shinohara, N., and Tokue, A. (1994) Antitumour effect of a synthetic analogue of fumagillin on murine renal carcinoma. Br. J. Urol. 74(4), 416-421
    • (1994) Br. J. Urol , vol.74 , Issue.4 , pp. 416-421
    • Morita, T.1    Shinohara, N.2    Tokue, A.3
  • 58
    • 0342704222 scopus 로고
    • Inhibition of tumor growth and metastasis of renal cell carcinoma by angiogenesis inhibitor TNP-470
    • Choi, H. R., Kim, S. C., Moon, W.-C. (1995) Inhibition of tumor growth and metastasis of renal cell carcinoma by angiogenesis inhibitor TNP-470. Proc. Am. Urol. Assoc. (Suppl.) 153, 402A
    • (1995) Proc. Am. Urol. Assoc. (Suppl.) , vol.153 , pp. 402
    • Choi, H.R.1    Kim, S.C.2    Moon, W.-C.3
  • 59
    • 0032323116 scopus 로고    scopus 로고
    • Inhibition of tumor growth and angiogenesis by vitamin D3 agents in murine renal cell carcinoma
    • Fujioka, T., Hasegawa, M., Ishikura, K., Matsushita, Y., Sato, M., and Tanji, S. (1998) Inhibition of tumor growth and angiogenesis by vitamin D3 agents in murine renal cell carcinoma. J. Urol. 160(1), 247-251
    • (1998) J. Urol , vol.160 , Issue.1 , pp. 247-251
    • Fujioka, T.1    Hasegawa, M.2    Ishikura, K.3    Matsushita, Y.4    Sato, M.5    Tanji, S.6
  • 61
    • 0031937612 scopus 로고    scopus 로고
    • Captopril inhibits tumour growth in a xenograft model of human renal cell carcinoma
    • Hii, S.I., Nicol, D. L., Gotley, D. C., Thompson, L. C., Green, M. K., and Jonsson, J. R. (1998) Captopril inhibits tumour growth in a xenograft model of human renal cell carcinoma. Br. J. Cancer 77(6), 880-883
    • (1998) Br. J. Cancer , vol.77 , Issue.6 , pp. 880-883
    • Hii, S.I.1    Nicol, D.L.2    Gotley, D.C.3    Thompson, L.C.4    Green, M.K.5    Jonsson, J.R.6
  • 62
    • 0031948807 scopus 로고    scopus 로고
    • Antiangiogenic chemotherapeutic agents: Characterization in comparison to their tumor growth inhibition in human renal cell carcinoma models. Clin
    • Schirner, M., Hoffmann, J., Menrad, A., and Schneider, M. R. (1998) Antiangiogenic chemotherapeutic agents: characterization in comparison to their tumor growth inhibition in human renal cell carcinoma models. Clin. Cancer Res. 4(5), 1331-1336
    • (1998) Cancer Res , vol.4 , Issue.5 , pp. 1331-1336
    • Schirner, M.1    Hoffmann, J.2    Menrad, A.3    Schneider, M.R.4
  • 63
    • 0027933191 scopus 로고
    • Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis
    • Takahashi, A., Sasaki, H., Kim, S. J., Tobisu, K., Kakizoe, T., Tsukamoto, T., et al. (1994) Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis. Cancer Res. 54(15), 4233-4237
    • (1994) Cancer Res , vol.54 , Issue.15 , pp. 4233-4237
    • Takahashi, A.1    Sasaki, H.2    Kim, S.J.3    Tobisu, K.4    Kakizoe, T.5    Tsukamoto, T.6
  • 64
    • 0027768808 scopus 로고
    • Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas
    • Brown, L. F., Berse, B., Jackman, R. W., Tognazzi, K., Manseau, E. J., Dvorak, H. F., et al. (1993) Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas. Am. J. Pathol. 143(5), 1255-1262
    • (1993) Am. J. Pathol , vol.143 , Issue.5 , pp. 1255-1262
    • Brown, L.F.1    Berse, B.2    Jackman, R.W.3    Tognazzi, K.4    Manseau, E.J.5    Dvorak, H.F.6
  • 65
    • 0029920054 scopus 로고    scopus 로고
    • Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein
    • Siemeister, G., Weindel, K., Mohrs, K., Barleon, B., Martiny-Baron, G., and Marme, D. (1996) Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein. Cancer Res. 56(10), 2299-2301
    • (1996) Cancer Res , vol.56 , Issue.10 , pp. 2299-2301
    • Siemeister, G.1    Weindel, K.2    Mohrs, K.3    Barleon, B.4    Martiny-baron, G.5    Marme, D.6
  • 66
    • 84921855452 scopus 로고    scopus 로고
    • Elevated vascular endothelial growth factor (vegf) and normal level of basic fibroblast growth factor (bFGF) in the sera of patients with renal cell carcinoma
    • Tsuchiya, N., Sato, K., Ogawa, O., Sasaki, R., Shimoda, N., Sato, S., Kato, T., (1998) Elevated vascular endothelial growth factor (vegf) and normal level of basic fibroblast growth factor (bFGF) in the sera of patients with renal cell carcinoma. J. Urol. (Suppl.) 159, No.5, 188
    • (1998) J. Urol. (Suppl.) , vol.159 , Issue.5 , pp. 188
    • Tsuchiya, N.1    Sato, K.2    Ogawa, O.3    Sasaki, R.4    Shimoda, N.5    Sato, S.6    Kato, T.7
  • 67
    • 0033061154 scopus 로고    scopus 로고
    • Expression pattern of vascular endothelial growth factor isoform is closely correlated with tumour stage and vascularisation in renal cell carcinoma
    • Tomisawa, M., Tokunaga, T., Oshika, Y., Tsuchida, T., Fukushima, Y., Sato, H., et al. (1999) Expression pattern of vascular endothelial growth factor isoform is closely correlated with tumour stage and vascularisation in renal cell carcinoma. Eur. J. Cancer 35(1), 133-137
    • (1999) Eur. J. Cancer , vol.35 , Issue.1 , pp. 133-137
    • Tomisawa, M.1    Tokunaga, T.2    Oshika, Y.3    Tsuchida, T.4    Fukushima, Y.5    Sato, H.6
  • 68
    • 0029785838 scopus 로고    scopus 로고
    • Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene
    • Gnarra, J. R., Zhou, S., Merrill, M. J., Wagner, J. R., Krumm, A., Papavassiliou, E., et al. (1996) Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene. Proc. Natl. Acad. Sci. USA 93(20), 10589-10594
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , Issue.20 , pp. 10589-10594
    • Gnarra, J.R.1    Zhou, S.2    Merrill, M.J.3    Wagner, J.R.4    Krumm, A.5    Papavassiliou, E.6
  • 69
    • 0029785321 scopus 로고    scopus 로고
    • Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein
    • Iliopoulos, O., Levy, A. P., Jiang, C., Kaelin, W. G., Jr., and Goldberg, M. A. (1996) Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein. Proc. Natl. Acad. Sci. USA 93(20), 10595-10599
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , Issue.20 , pp. 10595-10599
    • Iliopoulos, O.1    Levy, A.P.2    Jiang, C.3    Kaelin, W.G.4    Goldberg, M.A.5
  • 71
    • 84921838288 scopus 로고    scopus 로고
    • Molecular mediators of angiogenesis in renal cell carcinoma
    • Smith, N. D., Ivanovich, M., Bouck, N., and Campbell, S. C. (1999) Molecular mediators of angiogenesis in renal cell carcinoma. J. Urol. (Suppl.) 161(4), 137
    • (1999) J. Urol. (Suppl.) , vol.161 , Issue.4 , pp. 137
    • Smith, N.D.1    Ivanovich, M.2    Bouck, N.3    Campbell, S.C.4
  • 72
    • 0025987287 scopus 로고
    • Increased serum levels of basic fibroblast growth factor in patients with renal cell carcinoma. Biochem. Biophys. Res
    • Fujimoto, K., Ichimori, Y., Kakizoe, T., Okajima, E., Sakamoto, H., Sugimura, T., et al. (1991) Increased serum levels of basic fibroblast growth factor in patients with renal cell carcinoma. Biochem. Biophys. Res. Commun. 180(1), 386-392
    • (1991) Commun , vol.180 , Issue.1 , pp. 386-392
    • Fujimoto, K.1    Ichimori, Y.2    Kakizoe, T.3    Okajima, E.4    Sakamoto, H.5    Sugimura, T.6
  • 73
    • 0029566055 scopus 로고
    • Increased serum levels of basic fibroblast growth factor (bFGF) are associated with progressive lung metastases in advanced renal cell carcinoma patients
    • Duensing, S., Grosse, J., and Atzpodien, J. (1995) Increased serum levels of basic fibroblast growth factor (bFGF) are associated with progressive lung metastases in advanced renal cell carcinoma patients. Anticancer Res. 15(5B), 2331-2333
    • (1995) Anticancer Res , vol.15 , Issue.5B , pp. 2331-2333
    • Duensing, S.1    Grosse, J.2    Atzpodien, J.3
  • 74
    • 7144233809 scopus 로고    scopus 로고
    • Analysis of retinoid acid receptor beta (rar-beta) expression, angiogenesis and apoptosis in tumor specimens from patients with renal cell carcinoma treated with interferon alfa-2A and 13-CIS-retinoic acid: Correlation with response
    • Nanus, D. M., Leung, A., Hutchinson, B., Brown, K. T., Lotan, R., Reuter, V. E., Motzer, R. J. (1997) Analysis of retinoid acid receptor beta (rar-beta) expression, angiogenesis and apoptosis in tumor specimens from patients with renal cell carcinoma treated with interferon alfa-2A and 13-CIS-retinoic acid: correlation with response. J. Urol. 157, No. 4, 277
    • (1997) J. Urol , vol.157 , Issue.4 , pp. 277
    • Nanus, D.M.1    Leung, A.2    Hutchinson, B.3    Brown, K.T.4    Lotan, R.5    Reuter, V.E.6    Motzer, R.J.7
  • 75
    • 0027934194 scopus 로고
    • Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells
    • Singh, R. K., Bucana, C. D., Gutman, M., Fan, D., Wilson, M. R., and Fidler, I. J. (1994) Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells. Am. J. Pathol. 145(2), 365-374
    • (1994) Am. J. Pathol , vol.145 , Issue.2 , pp. 365-374
    • Singh, R.K.1    Bucana, C.D.2    Gutman, M.3    Fan, D.4    Wilson, M.R.5    Fidler, I.J.6
  • 76
    • 0030897074 scopus 로고    scopus 로고
    • Serum transforming growth factor-beta1 in patients with renal cell carcinoma
    • Wunderlich, H., Steiner, T., Junker, U., Knofel, B., Schlichter, A., and Schubert, J. (1997) Serum transforming growth factor-beta1 in patients with renal cell carcinoma. J. Urol. 157(5), 1602-1603
    • (1997) J. Urol , vol.157 , Issue.5 , pp. 1602-1603
    • Wunderlich, H.1    Steiner, T.2    Junker, U.3    Knofel, B.4    Schlichter, A.5    Schubert, J.6
  • 77
    • 0007045507 scopus 로고    scopus 로고
    • Induction of angiogenesis in renal cell carcinoma (RCC)? Investigation of regulatory cytokines and control mechanism in vivo and in vitro
    • Petri, E., Feil, G., Wechsel, H. W., Bichler K.-H., (1997) Induction of angiogenesis in renal cell carcinoma (RCC)? Investigation of regulatory cytokines and control mechanism in vivo and in vitro. J. Urol. (Suppl.) 157, No. 4, 377
    • (1997) J. Urol , vol.157 , Issue.4 , pp. 377
    • Petri, E.1    Feil, G.2    Wechsel, H.W.3    Bichler, K.-H.4
  • 78
    • 84921870670 scopus 로고    scopus 로고
    • Systemic elevation and implication for physiology of hepatocyte growth factor/scatter factor (HGF/ SF) in renal cell carcinoma (RCC)
    • Petri, E., Wechsel, H. W., Feil, G., and Bichler, K.-H. (1997) Systemic elevation and implication for physiology of hepatocyte growth factor/scatter factor (HGF/ SF) in renal cell carcinoma (RCC). J. Urol. (Suppl.) 157, No. 4, 377
    • (1997) J. Urol. (Suppl.) , vol.157 , Issue.4 , pp. 377
    • Petri, E.1    Wechsel, H.W.2    Feil, G.3    Bichler, K.-H.4
  • 79
    • 84921865639 scopus 로고
    • Quantification of hepatocyte growth factor (HGF) gene expression in renal cell carcinoma (RCC)
    • Kano, M., Horie, S., Nakamura, K., Okui, N., and Kawabe, K. (1995) Quantification of hepatocyte growth factor (HGF) gene expression in renal cell carcinoma (RCC). Proc. Am. Urol. Assoc. (Suppl.) 153, 496A
    • (1995) Proc. Am. Urol. Assoc , vol.153 , pp. 496
    • Kano, M.1    Horie, S.2    Nakamura, K.3    Okui, N.4    Kawabe, K.5
  • 80
    • 0030758780 scopus 로고    scopus 로고
    • Correlation between thymidine phosphorylase expression and prognosis in human renal cell carcinoma
    • Imazano, Y., Takebayashi, Y., Nishiyama, K., Akiba, S., Miyadera, K., Yamada, Y., et al. (1997) Correlation between thymidine phosphorylase expression and prognosis in human renal cell carcinoma. J. Clin. Oncol. 15(7), 2570-2578
    • (1997) J. Clin. Oncol , vol.15 , Issue.7 , pp. 2570-2578
    • Imazano, Y.1    Takebayashi, Y.2    Nishiyama, K.3    Akiba, S.4    Miyadera, K.5    Yamada, Y.6
  • 81
    • 0030669894 scopus 로고    scopus 로고
    • Quantitative angiogenesis assays: Progress and problems
    • Jain, R. K., Schlenger, K., Hockel, M., and Yuan, F. (1997) Quantitative angiogenesis assays: progress and problems. Nat. Med. 3(11), 1203-1208
    • (1997) Nat. Med , vol.3 , Issue.11 , pp. 1203-1208
    • Jain, R.K.1    Schlenger, K.2    Hockel, M.3    Yuan, F.4
  • 82
    • 0025935924 scopus 로고
    • Assay and purification of naturally occurring inhibitor of angiogenesis
    • Polverini, P. J., Bouck, N. P., and Rastinejad, F. (1991) Assay and purification of naturally occurring inhibitor of angiogenesis. Methods Enzymol. 198, 440-450
    • (1991) Methods Enzymol , vol.198 , pp. 440-450
    • Polverini, P.J.1    Bouck, N.P.2    Rastinejad, F.3
  • 83
    • 0030833817 scopus 로고    scopus 로고
    • CD36 mediates the in vitro inhibitory effects of thrombospondin-1 on endothelial cells
    • Dawson, D. W., Pearce, S. F., Zhong, R., Silverstein, R. L., Frazier, W. A., and Bouck, N. P. (1997) CD36 mediates the in vitro inhibitory effects of thrombospondin-1 on endothelial cells. J. Cell Biol. 138(3), 707-717
    • (1997) J. Cell Biol , vol.138 , Issue.3 , pp. 707-717
    • Dawson, D.W.1    Pearce, S.F.2    Zhong, R.3    Silverstein, R.L.4    Frazier, W.A.5    Bouck, N.P.6
  • 84
    • 0345109257 scopus 로고    scopus 로고
    • Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma
    • Kugler, A., Hemmerlein, B., Thelen, P., Kallerhoff, M., Radzun, H. J., and Ringert, R. H. (1998) Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma. J. Urol. 160(5), 1914-1918
    • (1998) J. Urol , vol.160 , Issue.5 , pp. 1914-1918
    • Kugler, A.1    Hemmerlein, B.2    Thelen, P.3    Kallerhoff, M.4    Radzun, H.J.5    Ringert, R.H.6
  • 85
    • 0021717225 scopus 로고
    • Mechanisms of neovascularization. Vascular sprouting can occur without proliferation of endothelial cells
    • Sholley, M. M., Ferguson, G. P., Seibel, H. R., Montour, J. L., and Wilson, J. D. (1984) Mechanisms of neovascularization. Vascular sprouting can occur without proliferation of endothelial cells. Lab. Invest. 51(6), 624-634
    • (1984) Lab. Invest , vol.51 , Issue.6 , pp. 624-634
    • Sholley, M.M.1    Ferguson, G.P.2    Seibel, H.R.3    Montour, J.L.4    Wilson, J.D.5
  • 86
    • 0032211360 scopus 로고    scopus 로고
    • Von Hippel-Lindau gene-mediated growth suppression and induction of differentiation in renal cell carcinoma cells grown as multicellular tumor spheroids
    • Lieubeau-Teillet, B., Rak, J., Jothy, S., Iliopoulos, O., Kaelin, W., and Kerbel, R. S. (1998) von Hippel-Lindau gene-mediated growth suppression and induction of differentiation in renal cell carcinoma cells grown as multicellular tumor spheroids. Cancer Res. 58 (21), 4957-4962
    • (1998) Cancer Res , vol.58 , Issue.21 , pp. 4957-4962
    • Lieubeau-teillet, B.1    Rak, J.2    Jothy, S.3    Iliopoulos, O.4    Kaelin, W.5    Kerbel, R.S.6
  • 87
    • 0032908982 scopus 로고    scopus 로고
    • Protective function of von Hippel-Lindau protein against impaired protein processing in renal carcinoma cells
    • Gorospe, M., Egan, J. M., Zbar, B., Lerman, M., Geil, L., Kuzmin, I., et al. (1999) Protective function of von Hippel-Lindau protein against impaired protein processing in renal carcinoma cells. Mol. Cell Biol. 19(2), 1289-1300
    • (1999) Mol. Cell Biol , vol.19 , Issue.2 , pp. 1289-1300
    • Gorospe, M.1    Egan, J.M.2    Zbar, B.3    Lerman, M.4    Geil, L.5    Kuzmin, I.6
  • 88
    • 0028951043 scopus 로고
    • Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
    • Holmgren, L., O’Reilly, M. S., and Folkman, J. (1995) Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nat. Med. 1(2), 149-153
    • (1995) Nat. Med , vol.1 , Issue.2 , pp. 149-153
    • Holmgren, L.1    O’reilly, M.S.2    Folkman, J.3
  • 89
    • 0029944122 scopus 로고    scopus 로고
    • Angiostatin induces and sustains dormancy of human primary tumors in mice
    • O’Reilly, M. S., Holmgren, L., Chen, C., and Folkman, J. (1996) Angiostatin induces and sustains dormancy of human primary tumors in mice. Nat. Med. 2(6), 689-692
    • (1996) Nat. Med , vol.2 , Issue.6 , pp. 689-692
    • O’reilly, M.S.1    Holmgren, L.2    Chen, C.3    Folkman, J.4
  • 90
    • 0026583597 scopus 로고    scopus 로고
    • M., et al. (1992) 13-cis-retinoic acid and interferon alpha-2a: Effective combination therapy for advanced squamous cell carcinoma of the skin. J. Natl
    • Lippman, S. M., Parkinson, D. R., Itri, L. M., Weber, R. S., Schantz, S. P., Ota, D. M., et al. (1992) 13-cis-retinoic acid and interferon alpha-2a: effective combination therapy for advanced squamous cell carcinoma of the skin. J. Natl. Cancer Inst. 84(4), 235-241
    • Cancer Inst , vol.84 , Issue.4 , pp. 235-241
    • Lippman, S.M.1    Parkinson, D.R.2    Itri, L.M.3    Weber, R.S.4    Schantz, S.P.5    Ota, D.6
  • 91
    • 0033538517 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor: A potent inhibitor of angiogenesis
    • Dawson, D. W., Volpert, O. V., Gillis, P., Crawford, S. E., Xu, H., Benedict, W., et al. (1999) Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science 285(5425), 245-248
    • (1999) Science , vol.285 , Issue.5425 , pp. 245-248
    • Dawson, D.W.1    Volpert, O.V.2    Gillis, P.3    Crawford, S.E.4    Xu, H.5    Benedict, W.6
  • 93
    • 0033074437 scopus 로고    scopus 로고
    • Renal cell carcinoma: Management of advanced disease
    • Figlin, R. A. (1999) Renal cell carcinoma: management of advanced disease. J. Urol. 161(2), 381-387
    • (1999) J. Urol , vol.161 , Issue.2 , pp. 381-387
    • Figlin, R.A.1
  • 94
    • 0029165480 scopus 로고
    • Interferon alfa-2a and 13-cis-retinoic acid in renal cell carcinoma: Antitumor activity in a phase II trial and interactions in vitro
    • Motzer, R. J., Schwartz, L., Law, T. M., Murphy, B. A., Hoffman, A. D., Albino, A. P., et al. (1995) Interferon alfa-2a and 13-cis-retinoic acid in renal cell carcinoma: antitumor activity in a phase II trial and interactions in vitro. J. Clin. Oncol. 13(8), 1950-1957
    • (1995) J. Clin. Oncol , vol.13 , Issue.8 , pp. 1950-1957
    • Motzer, R.J.1    Schwartz, L.2    Law, T.M.3    Murphy, B.A.4    Hoffman, A.D.5    Albino, A.P.6
  • 95
    • 0342444312 scopus 로고    scopus 로고
    • A Multi-Institutional Study of the Angiogenesis Inhibitior TNP-470 in Metastatic Renal Cell Carcinoma (RCC)
    • Stadler, W. M., Shapiro, C. L., Sosmann, J., Clark, J., Vogelzang, N. J., and Kuzel, T. (1998) A Multi-Institutional Study of the Angiogenesis Inhibitior TNP-470 in Metastatic Renal Cell Carcinoma (RCC). Proc. Am. Soc. Clin. Oncol. 17, 310A
    • (1998) Proc. Am. Soc. Clin. Oncol , vol.17 , pp. 310
    • Stadler, W.M.1    Shapiro, C.L.2    Sosmann, J.3    Clark, J.4    Vogelzang, N.J.5    Kuzel, T.6
  • 96
    • 0031106193 scopus 로고    scopus 로고
    • An EORTC phase II study of the efficacy and safety of linomide in the treatment of advanced renal cell carcinoma
    • Pawinski, A., van Oosterom, A. T., de Wit, R., Fossa, S., Croles, J., Svedberg, A., et al. (1997) An EORTC phase II study of the efficacy and safety of linomide in the treatment of advanced renal cell carcinoma. Eur. J. Cancer 33(3), 496-499
    • (1997) Eur. J. Cancer , vol.33 , Issue.3 , pp. 496-499
    • Pawinski, A.1    Van Oosterom, A.T.2    De Wit, R.3    Fossa, S.4    Croles, J.5    Svedberg, A.6
  • 97
    • 17644431683 scopus 로고    scopus 로고
    • EORTC phase II study of daily oral linomide in metastatic renal cell carcinoma patients with good prognostic factors
    • de Wit, R., Pawinsky, A., Stoter, G., van Oosterom, A. T., Fossa, S. D., Paridaens, R., et al. (1997) EORTC phase II study of daily oral linomide in metastatic renal cell carcinoma patients with good prognostic factors. Eur. J. Cancer 33(3), 493-495
    • (1997) Eur. J. Cancer , vol.33 , Issue.3 , pp. 493-495
    • De Wit, R.1    Pawinsky, A.2    Stoter, G.3    Van Oosterom, A.T.4    Fossa, S.D.5    Paridaens, R.6
  • 98
    • 12644251975 scopus 로고    scopus 로고
    • The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin
    • Gately, S., Twardowski, P., Stack, M. S., Cundiff, D. L., Grella, D., Castellino, F. J., et al. (1997) The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin. Proc. Natl. Acad. Sci. USA 94(20), 10,868-10,872
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , Issue.20 , pp. 868-872
    • Gately, S.1    Twardowski, P.2    Stack, M.S.3    Cundiff, D.L.4    Grella, D.5    Castellino, F.J.6
  • 99
    • 0026486664 scopus 로고
    • Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease
    • Teicher, B. A., Sotomayor, E. A., and Huang, Z. D. (1992) Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease. Cancer Res. 52(23), 6702-6704
    • (1992) Cancer Res , vol.52 , Issue.23 , pp. 6702-6704
    • Teicher, B.A.1    Sotomayor, E.A.2    Huang, Z.D.3
  • 100
    • 0028305809 scopus 로고
    • Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents
    • Teicher, B. A., Holden, S. A., Ara, G., Sotomayor, E. A., Huang, Z. D., Chen, Y. N., et al. (1994) Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents. Int. J. Cancer 57(6), 920-925
    • (1994) Int. J. Cancer , vol.57 , Issue.6 , pp. 920-925
    • Teicher, B.A.1    Holden, S.A.2    Ara, G.3    Sotomayor, E.A.4    Huang, Z.D.5    Chen, Y.N.6
  • 101
    • 0025166396 scopus 로고
    • Inhibition of angiogenesis by recombinant human platelet factor-4 and related peptides
    • Maione, T. E., Gray, G. S., Petro, J., Hunt, A. J., Donner, A. L., Bauer, S. I., et al. (1990) Inhibition of angiogenesis by recombinant human platelet factor-4 and related peptides. Science 247(4938), 77-79
    • (1990) Science , vol.247 , Issue.4938 , pp. 77-79
    • Maione, T.E.1    Gray, G.S.2    Petro, J.3    Hunt, A.J.4    Donner, A.L.5    Bauer, S.I.6
  • 102
    • 0024419176 scopus 로고
    • Inhibition of in vitro vascular endothelial cell proliferation and in vivo neovascularization by low-dose methotrexate
    • Hirata, S., Matsubara, T., Saura, R., Tateishi, H., and Hirohata, K. (1989) Inhibition of in vitro vascular endothelial cell proliferation and in vivo neovascularization by low-dose methotrexate. Arthritis Rheum. 32(9), 1065-1073
    • (1989) Arthritis Rheum , vol.32 , Issue.9 , pp. 1065-1073
    • Hirata, S.1    Matsubara, T.2    Saura, R.3    Tateishi, H.4    Hirohata, K.5
  • 104
    • 0027536872 scopus 로고
    • Inhibition of angiogenesis by antiestrogens
    • Gagliardi, A. and Collins, D. C. (1993) Inhibition of angiogenesis by antiestrogens. Cancer Res. 53(3), 533-535
    • (1993) Cancer Res , vol.53 , Issue.3 , pp. 533-535
    • Gagliardi, A.1    Collins, D.C.2
  • 105
    • 0027298410 scopus 로고
    • Suramin: A novel antineoplastic agent with multiple potential mechanisms of action
    • Stein, C. A. (1993) Suramin: a novel antineoplastic agent with multiple potential mechanisms of action. Cancer Res. 53, 2239-2248
    • (1993) Cancer Res , vol.53 , pp. 2239-2248
    • Stein, C.A.1
  • 106
    • 0030772175 scopus 로고    scopus 로고
    • Clinical trials of antiangiogenic agents
    • Twardowski, P. and Gradishar, W. J. (1997) Clinical trials of antiangiogenic agents. Curr. Opin. Oncol. 9(6), 584-589
    • (1997) Curr. Opin. Oncol , vol.9 , Issue.6 , pp. 584-589
    • Twardowski, P.1    Gradishar, W.J.2
  • 107
    • 0030932849 scopus 로고    scopus 로고
    • Tumor-associated angiogenesis: Mechanisms, clinical implications, and therapeutic strategies
    • Pluda, J. M. (1997) Tumor-associated angiogenesis: mechanisms, clinical implications, and therapeutic strategies. Semin. Oncol. 24(2), 203-218
    • (1997) Semin. Oncol , vol.24 , Issue.2 , pp. 203-218
    • Pluda, J.M.1
  • 108
    • 0028670833 scopus 로고
    • Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • Brooks, P. C., Montgomery, A. M., Rosenfeld, M., Reisfeld, R. A., Hu, T., Klier, G., et al. (1994) Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79(7), 1157-1164
    • (1994) Cell , vol.79 , Issue.7 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.2    Rosenfeld, M.3    Reisfeld, R.A.4    Hu, T.5    Klier, G.6
  • 109
    • 0023715794 scopus 로고
    • Inhibition of angiogenesis through modulation of collagen metabolism
    • Ingber, D. and Folkman, J. (1988) Inhibition of angiogenesis through modulation of collagen metabolism. Lab Invest. 59(1), 44-51
    • (1988) Lab Invest , vol.59 , Issue.1 , pp. 44-51
    • Ingber, D.1    Folkman, J.2
  • 110
    • 0027197245 scopus 로고
    • Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
    • Kim, K. J., Li, B., Winer, J., Armanini, M., Gillett, N., Phillips, H. S., et al. (1993) Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362(6423), 841-844
    • (1993) Nature , vol.362 , Issue.6423 , pp. 841-844
    • Kim, K.J.1    Li, B.2    Winer, J.3    Armanini, M.4    Gillett, N.5    Phillips, H.S.6
  • 111
    • 0030031898 scopus 로고    scopus 로고
    • Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis
    • Claffey, K. P., Brown, L. F., del Aguila, L. F., Tognazzi, K., Yeo, K. T., Manseau, E. J., et al. (1996) Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis. Cancer Res. 56(1), 172-181
    • (1996) Cancer Res , vol.56 , Issue.1 , pp. 172-181
    • Claffey, K.P.1    Brown, L.F.2    Del Aguila, L.F.3    Tognazzi, K.4    Yeo, K.T.5    Manseau, E.J.6
  • 112
    • 13144262858 scopus 로고    scopus 로고
    • Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate
    • Goldman, C. K., Kendall, R. L., Cabrera, G., Soroceanu, L., Heike, Y., Gillespie, G. Y., et al. (1998) Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate. Proc. Natl. Acad. Sci. USA 95(15), 8795-8800
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , Issue.15 , pp. 8795-8800
    • Goldman, C.K.1    Kendall, R.L.2    Cabrera, G.3    Soroceanu, L.4    Heike, Y.5    Gillespie, G.Y.6
  • 113
    • 0031965353 scopus 로고    scopus 로고
    • Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor
    • Lin, P., Sankar, S., Shan, S., Dewhirst, M. W., Polverini, P. J., Quinn, T. Q., et al. (1998) Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor. Cell Growth Differ. 9(1), 49-58
    • (1998) Cell Growth Differ , vol.9 , Issue.1 , pp. 49-58
    • Lin, P.1    Sankar, S.2    Shan, S.3    Dewhirst, M.W.4    Polverini, P.J.5    Quinn, T.Q.6
  • 114
    • 0013560389 scopus 로고    scopus 로고
    • Effect of the Flk-1 antagonist SU5416 on tumor growth, angiogenesis and microhemodynamics (abstract)
    • Vajkoczy, P., Menger, M. D., and Vollmar, B. (1998) Effect of the Flk-1 antagonist SU5416 on tumor growth, angiogenesis and microhemodynamics (abstract). Proc. Am. Assoc. Cancer Res. 39, 96
    • (1998) Proc. Am. Assoc. Cancer Res , vol.39 , pp. 96
    • Vajkoczy, P.1    Menger, M.D.2    Vollmar, B.3
  • 115
    • 0010547293 scopus 로고    scopus 로고
    • Angiostatic and antitumoral activity of AE-914 (Neovastat), a molecular fraction derived from shark cartilage (abstract)
    • Dupont, E., Alaoui-Jamal, M., and Wang, T. (1998) Angiostatic and antitumoral activity of AE-914 (Neovastat), a molecular fraction derived from shark cartilage (abstract). Proc. Am. Assoc. Cancer Res. 38, 227
    • (1998) Proc. Am. Assoc. Cancer Res , vol.38 , pp. 227
    • Dupont, E.1    Alaoui-jamal, M.2    Wang, T.3
  • 116
    • 0032054052 scopus 로고    scopus 로고
    • Two vascular apoptosis inducing proteins from a snake venom are members of the metalloproteinase/disintegrin family
    • Nasuda, S., Hayasha, H., and Arakis, S. (1998) Two vascular apoptosis inducing proteins from a snake venom are members of the metalloproteinase/disintegrin family. Eur. J. Biochem. 253, 36-41
    • (1998) Eur. J. Biochem , vol.253 , pp. 36-41
    • Nasuda, S.1    Hayasha, H.2    Arakis, S.3
  • 117
    • 0027482301 scopus 로고
    • Expression of basic fibroblast growth factor in primary human renal tumors: Correlation with poor survival
    • Nanus, D. M., Schmitz-Drager, B. J., Motzer, R. J., Lee, A. C., Vlamis, V., Cordon-Cardo, C., et al. (1993) Expression of basic fibroblast growth factor in primary human renal tumors: correlation with poor survival. J. Natl. Cancer Inst. 85(19), 1597-1599
    • (1993) J. Natl. Cancer Inst , vol.85 , Issue.19 , pp. 1597-1599
    • Nanus, D.M.1    Schmitz-drager, B.J.2    Motzer, R.J.3    Lee, A.C.4    Vlamis, V.5    Cordon-cardo, C.6
  • 118
    • 0029782859 scopus 로고    scopus 로고
    • Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor
    • Cheng, S. Y., Huang, H. J., Nagane, M., et al. (1998) Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Proc. Natl. Acad. Sci. USA 93, 8502-8507.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8502-8507
    • Cheng, S.Y.1    Huang, H.J.2    Nagane, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.