Evidence of disseminated intravascular coagulation in a hemorrhagic fever with renal syndrome-scoring models and severe illness

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Sundberg, Erik ^a   Hultdin, Johan ^a   Nilsson, Sofie ^a   Ahlm, Clas ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CREATININE; D DIMER;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BLEEDING; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIAGNOSTIC TEST; DIAGNOSTIC TEST ACCURACY STUDY; DIALYSIS; DISEASE SEVERITY; DISSEMINATED INTRAVASCULAR CLOTTING; FEMALE; FIBRINOGEN BLOOD LEVEL; FIBRINOGEN CRP RATIO; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMAN; INTENSIVE CARE; INTERMETHOD COMPARISON; INTERNATIONAL NORMALIZED RATIO; INTERNATIONAL SOCIETY ON THROMBOSIS AND HAEMOSTASIS SCORE; MAJOR CLINICAL STUDY; MALE; OXYGEN CONSUMPTION; PROTHROMBIN TIME; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; SYSTOLIC BLOOD PRESSURE; THROMBOCYTE COUNT; THROMBOCYTE TRANSFUSION; THROMBOEMBOLISM; BIOLOGICAL MODEL; HOSPITALIZATION; MIDDLE AGED; PATHOLOGY; PREDICTIVE VALUE; RECEIVER OPERATING CHARACTERISTIC;

ADULT; AGED; AGED, 80 AND OVER; AREA UNDER CURVE; DISSEMINATED INTRAVASCULAR COAGULATION; FEMALE; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMANS; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; PREDICTIVE VALUE OF TESTS; ROC CURVE; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 79959534769     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021134     Document Type: Article

References (53)

1. Gould EA, Solomon T, (2008) Pathogenic flaviviruses. Lancet 371: 500-509.
2. Peters CJ, Zaki SR, (2002) Role of the endothelium in viral hemorrhagic fevers. Critical Care Medicine 30: S268-S273.
3. Gibbons RV, Vaughn DW, (2002) Dengue: an escalating problem. British Medical Journal 324: 1563-1566.
4. Semenza JC, Menne B, (2009) Climate change and infectious diseases in Europe. Lancet Infectious Diseases 9: 365-375.
5. Gowen BB, Holbrook MR, (2008) Animal models of highly pathogenic RNA viral infections: Hemorrhagic fever viruses. Antiviral Research 78: 79-90.
6. Feldmann H, Geisbert TW, (2011) Ebola haemorrhagic fever. Lancet 377: 849-862.
7. Cohen J, (2004) Containing the threat- Don't forget Ebola. Plos Medicine 1: 188-189.
8. Schmaljohn C, Hjelle B, (1997) Hantaviruses: a global disease problem. Emerg Infect Dis 3: 95-104.
9. Mackow ER, Gavrilovskaya IN, (2009) Hantavirus regulation of endothelial cell functions. Thrombosis and Haemostasis 102: 1030-1041.
10. Hjertqvist M, Klein SL, Ahlm C, Klingstrom J, (2010) Mortality Rate Patterns for Hemorrhagic Fever with Renal Syndrome Caused by Puumala Virus. Emerging Infectious Diseases 16: 1584-1586.
11. Jonsson CB, Figueiredo LTM, Vapalahti O, (2010) A Global Perspective on Hantavirus Ecology, Epidemiology, and Disease. Clinical Microbiology Reviews 23: 412-41.
12. Vapalahti O, Mustonen J, Lundkvist A, Henttonen H, Plyusnin A, et al. (2003) Hantavirus infections in Europe. Lancet Infect Dis 3: 653-661.
13. Settergren B, (2000) Clinical aspects of nephropathia epidemica (Puumala virus infection) in Europe: a review. Scand J Infect Dis 32: 125-132.
14. Rasche FM, Uhel B, Ulrich R, Kruger DH, Karges W, et al. (2004) Thrombocytopenia and acute renal failure in Puumala hantavirus infections. Emerging Infectious Diseases 10: 1420-1425.
15. Liu Z, Gao M, Han Q, Fang J, Zhao Q, et al. (2008) Intensity of platelet beta(3) integrin in patients with hemorrhagic fever with renal syndrome and its correlation with disease severity. Viral Immunol 21: 255-262.
16. Lutteke N, Raftery MJ, Lalwani P, Lee MH, Giese T, et al. (2010) Switch to high-level virus replication and HLA class I upregulation in differentiating megakaryocytic cells after infection with pathogenic hantavirus. Virology 405: 70-80.
17. Sironen T, Klingstrom J, Vaheri A, Andersson LC, Lundkvist A, et al. (2008) Pathology of Puumala hantavirus infection in macaques. PLoS One 3: e3035.
18. Bray M, (2005) Pathogenesis of viral hemorrhagic fever. Curr Opin Immunol 17: 399-403.
19. Klingstrom J, Hardestam J, Stoltz M, Zuber B, Lundkvist A, et al. (2006) Loss of cell membrane integrity in puumala hantavirus-infected patients correlates with levels of epithelial cell apoptosis and perforin. J Virol 80: 8279-8282.
20. Zaki SR, Greer PW, Coffield LM, Goldsmith CS, Nolte KB, et al. (1995) Hantavirus pulmonary syndrome. Pathogenesis of an emerging infectious disease. Am J Pathol 146: 552-579.
21. Esmon CT, (2008) Crosstalk between inflammation and thrombosis. Maturitas 61: 122-131.
22. Levi M, Opal SM, (2006) Coagulation abnormalities in critically ill patients. Crit Care 10: 222.
23. Khaiboullina SF, St Jeor SC, (2002) Hantavirus immunology. Viral Immunol 15: 609-625.
24. Chen JP, Cosgriff TM, (2000) Hemorrhagic fever virus-induced changes in hemostasis and vascular biology. Blood Coagul Fibrinolysis 11: 461-483.
25. Ong A, Sandar M, Chen MI, Sin LY, (2007) Fatal dengue hemorrhagic fever in adults during a dengue epidemic in Singapore. International Journal of Infectious Diseases 11: 263-267.
26. Mahanty S, Bray M, (2004) Pathogenesis of filoviral haemorrhagic fevers. Lancet Infectious Diseases 4: 487-498.
27. Settergren B, Juto P, Trollfors B, Wadell G, Norrby SR, (1989) Clinical characteristics of nephropathia epidemica in Sweden: prospective study of 74 cases. Rev Infect Dis 11: 921-927.
28. Settergren B, Norrby R, Naslund U, Wadell G, (1983) Case of epidemic nephropathy associated with disseminated intravascular coagulation. Lancet 2: 1419.
29. Valtonen M, Kauppila M, Kotilainen P, Lahdevirta J, Svartback CM, et al. (1995) Four fatal cases of nephropathia epidemica. Scand J Infect Dis 27: 515-517.
30. Lee M, Lee JS, Kim BK, (1983) Disseminated intravascular coagulation in Korean hemorrhagic fever. Bibl Haematol pp. 181-199.
31. Linderholm M, Settergren B, Ahlm C, Burman LA, Traff S, et al. (1991) A Swedish fatal case of nephropathia epidemica. Scand J Infect Dis 23: 501-502.
32. Cosgriff TM, Lee HW, See AF, Parrish DB, Moon JS, et al. (1991) Platelet dysfunction contributes to the haemostatic defect in haemorrhagic fever with renal syndrome. Trans R Soc Trop Med Hyg 85: 660-663.
33. Forslund T, Saltevo J, Anttinen J, Auvinen S, Brummer-Korvenkontios M, et al. (1992) Complications of nephropathia epidemica: three cases. Journal of Internal Medicine 232: 87-90.
34. Lähdevirta J, (1989) The minor problem of hemostatic impairment in nephropathia epidemica, the mild Scandinavian form of hemorrhagic fever with renal syndrome. Reviews of infectious diseases 11: (Supplement 4): s860-863.
35. Taylor FB Jr, Toh CH, Hoots WK, Wada H, Levi M, (2001) Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation. Thromb Haemost 86: 1327-1330.
36. Takemitsu T, Wada H, Hatada T, Ohmori Y, Ishikura K, et al. (2011) Prospective evaluation of three different diagnostic criteria for disseminated intravascular coagulation. Thrombosis and Haemostasis 105: 40-44.
37. Kim HK, Lee DS, Kang SH, Kim JQ, Park S, et al. (2007) Utility of the fibrinogen/C-reactive protein ratio for the diagnosis of disseminated intravascular coagulation. Acta Haematol 117: 34-39.
38. Laine O, Makela S, Mustonen J, Huhtala H, Szanto T, et al. (2010) Enhanced thrombin formation and fibrinolysis during acute Puumala hantavirus infection. Thromb Res 126: 154-158.
39. Pettersson L, Boman J, Juto P, Evander M, Ahlm C, (2008) Outbreak of Puumala virus infection, Sweden. Emerg Infect Dis 14: 808-810.
40. Toh CH, Downey C, (2005) Performance and prognostic importance of a new clinical and laboratory scoring system for identifying non-overt disseminated intravascular coagulation. Blood Coagul Fibrinolysis 16: 69-74.
41. Andreotti F, Burzotta F, Maseri A, (1999) Fibrinogen as a marker of inflammation: a clinical view. Blood Coagul Fibrinolysis 10 (Suppl 1): S3-4.
42. Toh CH, Hoots WK, (2007) The scoring system of the Scientific and Standardisation Committee on Disseminated Intravascular Coagulation of the International Society on Thrombosis and Haemostasis: a 5-year overview. J Thromb Haemost 5: 604-606.
43. Bakhtiari K, Meijers JC, de Jonge E, Levi M, (2004) Prospective validation of the International Society of Thrombosis and Haemostasis scoring system for disseminated intravascular coagulation. Crit Care Med 32: 2416-2421.
44. Dempfle CE, Wurst M, Smolinski M, Lorenz S, Osika A, et al. (2004) Use of soluble fibrin antigen instead of D-dimer as fibrin-related marker may enhance the prognostic power of the ISTH overt DIC score. Thromb Haemost 91: 812-818.
45. Evander M, Eriksson I, Pettersson L, Juto P, Ahlm C, et al. (2007) Puumala hantavirus viremia diagnosed by real-time reverse transcriptase PCR using samples from patients with hemorrhagic fever and renal syndrome. J Clin Microbiol 45: 2491-2497.
46. Kanerva M, Paakkala A, Mustonen J, Paakkala T, Lahtela J, et al. (1996) Pulmonary involvement in nephropathia epidemica: Radiological findings and their clinical correlations. Clinical Nephrology 46: 369-378.
47. Huttunen NP, Makela S, Pokka T, Mustonen J, Uhari M, (2011) Systematic literature review of symptoms, signs and severity of serologically confirmed nephropathia epidemica in paediatric and adult patients. Scand J Infect Dis In press.
48. Vanderschueren S, De Weerdt A, Malbrain M, Vankersschaever D, Frans E, et al. (2000) Thrombocytopenia and prognosis in intensive care. Crit Care Med 28: 1871-1876.
49. Voves C, Wuillemin WA, Zeerleder S, (2006) International Society on Thrombosis and Haemostasis score for overt disseminated intravascular coagulation predicts organ dysfunction and fatality in sepsis patients. Blood Coagulation & Fibrinolysis 17: 445-451.
50. Khemani R, Bart R, Alonzo T, Hatzakis G, Hallam D, et al. (2009) Disseminated intravascular coagulation score is associated with mortality for children with shock. Intensive Care Medicine 35: 327-333.
51. Oh D, Jang MJ, Lee SJ, Chong SY, Kang MS, et al. (2010) Evaluation of modified non-overt DIC criteria on the prediction of poor outcome in patients with sepsis. Thrombosis Research 126: 18-23.
52. Takeuchi T, Yamamoto T, Itoh M, Tsukada K, Yasue N, et al. (1991) Clinical studies on hemorrhagic fever with renal syndrome found in Nagoya City University Medical School. Kidney Int Suppl 35: S84-87.
53. Wada H, Hatada T, Okamoto K, Uchiyama T, Kawasugi K, et al. (2010) Modified non-overt DIC diagnostic criteria predict the early phase of overt-DIC. American Journal of Hematology 85: 691-694.