-
1
-
-
0036742053
-
Poor aqueous solubility - an industry wide problem in drug discovery
-
Lipinski, C. Poor aqueous solubility - an industry wide problem in drug discovery. Am. Pharm. Rev. 2002, 5, 82-85.
-
(2002)
Am. Pharm. Rev
, vol.5
, pp. 82-85
-
-
Lipinski, C.1
-
2
-
-
0028948839
-
A theoretical basis for a biopharmaceutic drug classification - the correlation of in-vitro drug product dissolution and in-vivo bioavailability
-
Amidon, G.L.; Lennernas, H.; Shah, V.P.; Crison, J.R. A theoretical basis for a biopharmaceutic drug classification - the correlation of in-vitro drug product dissolution and in-vivo bioavailability. Pharm. Res. 1995, 12, 413-420.
-
(1995)
Pharm. Res
, vol.12
, pp. 413-420
-
-
Amidon, G.L.1
Lennernas, H.2
Shah, V.P.3
Crison, J.R.4
-
3
-
-
0033805179
-
In vitro-in vivo correlations for lipophilic, poorly water-soluble drugs
-
Dressman, J.B.; Reppas, C. In vitro-in vivo correlations for lipophilic, poorly water-soluble drugs. Eur. J. Pharm. Sci. 2000, 11, S73-S80.
-
(2000)
Eur. J. Pharm. Sci
, vol.11
-
-
Dressman, J.B.1
Reppas, C.2
-
4
-
-
0037026338
-
Investigation of the effects of grinding and co-grinding on physicochemical properties of glisentide
-
Mura, P.; Curi, M.; Faucci, M.T.; Gines-Dorado, J.M.; Bettinetti, G.P. Investigation of the effects of grinding and co-grinding on physicochemical properties of glisentide. J. Pharm. Biomed. Anal. 2002, 30, 227-237.
-
(2002)
J. Pharm. Biomed. Anal
, vol.30
, pp. 227-237
-
-
Mura, P.1
Curi, M.2
Faucci, M.T.3
Gines-Dorado, J.M.4
Bettinetti, G.P.5
-
5
-
-
36749050487
-
-
Mayersohn, M. In Modern Pharmaceutics; Banker, G.S. and Rhodes, C.T. Eds.; Drugs and the Pharmaceutical Sciences; Marcel Dekker, Inc.: New York, NY, 2002; 121, pp 23-66.
-
Mayersohn, M. In Modern Pharmaceutics; Banker, G.S. and Rhodes, C.T. Eds.; Drugs and the Pharmaceutical Sciences; Marcel Dekker, Inc.: New York, NY, 2002; Vol. 121, pp 23-66.
-
-
-
-
7
-
-
1842559836
-
Nanoparticle engineering processes for enhancing the dissolution rates of poorly water soluble drugs - a review
-
Hu, J.H.; Johnston, K.P.; Williams III, R.O. Nanoparticle engineering processes for enhancing the dissolution rates of poorly water soluble drugs - a review. Drug Dev. Ind. Pharm. 2004, 30, 247-258.
-
(2004)
Drug Dev. Ind. Pharm
, vol.30
, pp. 247-258
-
-
Hu, J.H.1
Johnston, K.P.2
Williams III, R.O.3
-
8
-
-
1342281182
-
Micron-size drug particles: Common and novel micronization techniques
-
Rasenack, N.; Muller, B.W. Micron-size drug particles: Common and novel micronization techniques. Pharm. Dev. Technol. 2004, 9, 1-13.
-
(2004)
Pharm. Dev. Technol
, vol.9
, pp. 1-13
-
-
Rasenack, N.1
Muller, B.W.2
-
9
-
-
0033230727
-
Strategies for particle design using supercritical fluid technologies
-
York, P. Strategies for particle design using supercritical fluid technologies. Pharm. Sci. Tech. Today 1999, 2, 430-440.
-
(1999)
Pharm. Sci. Tech. Today
, vol.2
, pp. 430-440
-
-
York, P.1
-
10
-
-
0037151556
-
Preparation of cyclosporine A nanoparticles by evaporative precipitation into aqueous solution
-
Chen, X.; Young, T.J.; Sarkari, M.; Williams III, R.O.; Johnston, K.P. Preparation of cyclosporine A nanoparticles by evaporative precipitation into aqueous solution. Int. J. Pharm. 2002, 242, 3-14.
-
(2002)
Int. J. Pharm
, vol.242
, pp. 3-14
-
-
Chen, X.1
Young, T.J.2
Sarkari, M.3
Williams III, R.O.4
Johnston, K.P.5
-
11
-
-
0037189994
-
Enhanced drug dissolution using evaporative precipitation into aqueous solution
-
Sarkari, M.; Brown, J.; Chen, X.; Swinnea, S.; Williams III, R.O.; Johnston, K.P. Enhanced drug dissolution using evaporative precipitation into aqueous solution. Int. J. Pharm. 2002, 243, 17-31.
-
(2002)
Int. J. Pharm
, vol.243
, pp. 17-31
-
-
Sarkari, M.1
Brown, J.2
Chen, X.3
Swinnea, S.4
Williams III, R.O.5
Johnston, K.P.6
-
12
-
-
0036746811
-
Improvement of dissolution rates of poorly water soluble APIs using novel spray freezing into liquid technology
-
Hu, J.H.; Rogers, T.L.; Brown, J.; Young, T.J; Johnston, K.P.; Williams III, R.O. Improvement of dissolution rates of poorly water soluble APIs using novel spray freezing into liquid technology. Pharm. Res. 2002, 19, 1278-1284.
-
(2002)
Pharm. Res
, vol.19
, pp. 1278-1284
-
-
Hu, J.H.1
Rogers, T.L.2
Brown, J.3
Young, T.J.4
Johnston, K.P.5
Williams III, R.O.6
-
13
-
-
0036849433
-
A novel particle engineering technology to enhance dissolution of poorly water soluble drugs: Spray-freezing into liquid
-
Rogers, T.L.; Nelsen, A.C.; Hu, J.; Brown, J.N.; Sarkari, M.; Young, T.J.; Johnston, K.P.; Williams III, R.O. A novel particle engineering technology to enhance dissolution of poorly water soluble drugs: spray-freezing into liquid. Eur. J. Pharm. Biopharm. 2002, 54, 271-280.
-
(2002)
Eur. J. Pharm. Biopharm
, vol.54
, pp. 271-280
-
-
Rogers, T.L.1
Nelsen, A.C.2
Hu, J.3
Brown, J.N.4
Sarkari, M.5
Young, T.J.6
Johnston, K.P.7
Williams III, R.O.8
-
14
-
-
0141764851
-
Investigation of processing parameters of spray freezing into liquid to prepare polyethylene glycol polymeric particles for drug delivery
-
Barron, M.K.; Young, T.J.; Johnston, K.P.; Williams III, R.O. Investigation of processing parameters of spray freezing into liquid to prepare polyethylene glycol polymeric particles for drug delivery. AAPS PharmSciTech 2003, 4, 90-102.
-
(2003)
AAPS PharmSciTech
, vol.4
, pp. 90-102
-
-
Barron, M.K.1
Young, T.J.2
Johnston, K.P.3
Williams III, R.O.4
-
15
-
-
0037333353
-
Enhanced aqueous dissolution of a poorly water soluble drug by novel particle engineering technology: Spray-freezing into liquid with atmospheric freeze-drying
-
Rogers, T.L.; Nelsen, A.C.; Sarkari, M.; Young, T.J.; Johnston, K.P.; Williams III, R.O. Enhanced aqueous dissolution of a poorly water soluble drug by novel particle engineering technology: Spray-freezing into liquid with atmospheric freeze-drying. Pharm. Res. 2003, 20, 485-493.
-
(2003)
Pharm. Res
, vol.20
, pp. 485-493
-
-
Rogers, T.L.1
Nelsen, A.C.2
Sarkari, M.3
Young, T.J.4
Johnston, K.P.5
Williams III, R.O.6
-
16
-
-
1142309798
-
Rapid dissolving high potency danazol powders produced by spray freezing into liquid process
-
Hu, J.; Johnston, K.P.; Williams III, R.O. Rapid dissolving high potency danazol powders produced by spray freezing into liquid process. Int. J. Pharm. 2004, 271, 145-154.
-
(2004)
Int. J. Pharm
, vol.271
, pp. 145-154
-
-
Hu, J.1
Johnston, K.P.2
Williams III, R.O.3
-
17
-
-
0037151528
-
A novel particle engineering technology: Spray-freezing into liquid
-
Rogers, T.L.; Hu, J.; Yu, Z.; Johnston, K.P.; Williams III, R.O. A novel particle engineering technology: spray-freezing into liquid. Int. J. Pharm. 2002, 242, 93-100.
-
(2002)
Int. J. Pharm
, vol.242
, pp. 93-100
-
-
Rogers, T.L.1
Hu, J.2
Yu, Z.3
Johnston, K.P.4
Williams III, R.O.5
-
18
-
-
1842865504
-
Preparation and characterization of microparticles containing peptide produced by a novel process: Spray freezing into liquid
-
Yu, Z.; Rogers, T.L; Hu, J.; Johnston, K.P.; Williams III, R.O. Preparation and characterization of microparticles containing peptide produced by a novel process: spray freezing into liquid. Eur. J. Pharm. Biopharm. 2002, 54, 221-228.
-
(2002)
Eur. J. Pharm. Biopharm
, vol.54
, pp. 221-228
-
-
Yu, Z.1
Rogers, T.L.2
Hu, J.3
Johnston, K.P.4
Williams III, R.O.5
-
19
-
-
0025006471
-
The Collapse Temperature in Freeze-Drying - Dependence on Measurement Methodology and Rate of Water Removal from the Glassy Phase
-
Pikal, M.J.; Shah, S. The Collapse Temperature in Freeze-Drying - Dependence on Measurement Methodology and Rate of Water Removal from the Glassy Phase. Int. J. Pharm. 1990, 62, 165-186.
-
(1990)
Int. J. Pharm
, vol.62
, pp. 165-186
-
-
Pikal, M.J.1
Shah, S.2
-
20
-
-
0025359216
-
The Secondary Drying Stage of Freeze-Drying - Drying Kinetics as a Function of Temperature and Chamber Pressure
-
Pikal, M.J.; Shah, S.; Roy, M.L.; Putman, R. The Secondary Drying Stage of Freeze-Drying - Drying Kinetics as a Function of Temperature and Chamber Pressure. Int. J. Pharm. 1990, 60, 203-217.
-
(1990)
Int. J. Pharm
, vol.60
, pp. 203-217
-
-
Pikal, M.J.1
Shah, S.2
Roy, M.L.3
Putman, R.4
-
21
-
-
0034933284
-
The ice nucleation temperature determines the primary drying rate of lyophilization for samples frozen on a temperature-controlled shelf
-
Searles, J.A.; Carpenter, J.F.; Randolph, T.W. The ice nucleation temperature determines the primary drying rate of lyophilization for samples frozen on a temperature-controlled shelf. J. Pharm. Sci. 2001, 90, 860-871.
-
(2001)
J. Pharm. Sci
, vol.90
, pp. 860-871
-
-
Searles, J.A.1
Carpenter, J.F.2
Randolph, T.W.3
-
22
-
-
4344595485
-
Rapid release tablet formulation of micronized danazol powder produced by spray freezing into liquid (SFL)
-
Hu, J.H.; Johnston, K.P.; Williams III, R.O. Rapid release tablet formulation of micronized danazol powder produced by spray freezing into liquid (SFL). J. Drug Del. Sci. Technol. 2004, 14, 299-304.
-
(2004)
J. Drug Del. Sci. Technol
, vol.14
, pp. 299-304
-
-
Hu, J.H.1
Johnston, K.P.2
Williams III, R.O.3
-
23
-
-
12444272525
-
Adsorption of gases in multimolecular layers
-
Brunauer, S.; Emmett, P.H.; Teller, E. Adsorption of gases in multimolecular layers. J. Am. Chem. Soc. 1938, 60, 309-319.
-
(1938)
J. Am. Chem. Soc
, vol.60
, pp. 309-319
-
-
Brunauer, S.1
Emmett, P.H.2
Teller, E.3
-
24
-
-
0242334090
-
Spray freezing into liquid (SFL) particle engineering technology to enhance dissolution of poorly water soluble drugs: Organic solvent versus organic/aqueous co-solvent systems
-
Hu, J.; Johnston, K.P.; Williams III, R.O. Spray freezing into liquid (SFL) particle engineering technology to enhance dissolution of poorly water soluble drugs: organic solvent versus organic/aqueous co-solvent systems. Eur. J. Pharm. Sci. 2003, 20, 295-303.
-
(2003)
Eur. J. Pharm. Sci
, vol.20
, pp. 295-303
-
-
Hu, J.1
Johnston, K.P.2
Williams III, R.O.3
-
25
-
-
0037333996
-
Micronized powders of a poorly water soluble drug produced by a spray-freezing into liquid-emulsion process
-
Rogers, T.L.; Overhoff, K.A.; Shah, P.; Santiago, P.; Yacaman, M.J.; Johnston, K.P.; Williams III, R.O. Micronized powders of a poorly water soluble drug produced by a spray-freezing into liquid-emulsion process. Eur. J. Pharm. Biopharm. 2003, 55, 161-172.
-
(2003)
Eur. J. Pharm. Biopharm
, vol.55
, pp. 161-172
-
-
Rogers, T.L.1
Overhoff, K.A.2
Shah, P.3
Santiago, P.4
Yacaman, M.J.5
Johnston, K.P.6
Williams III, R.O.7
-
26
-
-
0344095792
-
-
VCH Publishers, Inc, New York, NY
-
Myers, D. Surface Science and Technology; VCH Publishers, Inc.: New York, NY, 1992; pp 292-298.
-
(1992)
Surface Science and Technology
, pp. 292-298
-
-
Myers, D.1
-
27
-
-
0035292910
-
Influence of physicochemical properties on dissolution of drugs in die gastrointestinal tract
-
Horter, D.; Dressman, J.B. Influence of physicochemical properties on dissolution of drugs in die gastrointestinal tract. Adv. Drug Del. Rev. 2001, 46, 75-87.
-
(2001)
Adv. Drug Del. Rev
, vol.46
, pp. 75-87
-
-
Horter, D.1
Dressman, J.B.2
-
28
-
-
0037151467
-
Characterization of nifedipine solid dispersions
-
Cilurzo, F.; Minghetti, P.; Casiraghi, A.; Montanari, L. Characterization of nifedipine solid dispersions. Int. J. Pharm. 2002, 242, 313-317.
-
(2002)
Int. J. Pharm
, vol.242
, pp. 313-317
-
-
Cilurzo, F.1
Minghetti, P.2
Casiraghi, A.3
Montanari, L.4
-
29
-
-
1442348823
-
Study of the phase behavior of polyethylene glycol 6000-itraconazole solid dispersions using DSC
-
Wang, X.; Michoel, A.; Van den Mooter, G. Study of the phase behavior of polyethylene glycol 6000-itraconazole solid dispersions using DSC Int. J. Pharm. 2004, 272, 181-187.
-
(2004)
Int. J. Pharm
, vol.272
, pp. 181-187
-
-
Wang, X.1
Michoel, A.2
Van den Mooter, G.3
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