A mechanism for nerve cell excitation by norepinephrine via alpha-1 adrenoceptors: Inhibition of potassium M-current

Cellular and Molecular Neurobiology

Volumn 33, Issue 1, 2013, Pages 1-4

  Filippov, Alexander K ^a   Brown, David A ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

1 Adrenoceptors; M current; Norepinephrine; Phenylephrine; Potassium current; Sympathetic neurons

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; NORADRENALIN; PHENYLEPHRINE;

ACCURACY; ACTION POTENTIAL; AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL TISSUE; ANTIDROMIC STIMULATION; ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; MOLECULAR DYNAMICS; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL STIMULATION; NONHUMAN; POTASSIUM CURRENT; POTASSIUM M CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SPIKE; SYMPATHETIC GANGLION; VOLTAGE CLAMP;

ADRENERGIC ALPHA-1 RECEPTOR AGONISTS; ANIMALS; CELLS, CULTURED; GANGLIA, SYMPATHETIC; MEMBRANE POTENTIALS; NEURAL INHIBITION; NOREPINEPHRINE; PHENYLEPHRINE; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, VOLTAGE-GATED; RATS; RECEPTORS, ADRENERGIC, ALPHA-1;

RATTUS;

EID: 84871776941     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-012-9870-y     Document Type: Article

References (27)

1. Adams PR, Brown DA, Constanti A (1982a) M-currents and other potassium currents in bullfrog sympathetic neurones. J Physiol 330:537-572
2. Adams PR, Brown DA, Constanti A (1982b) Pharmacological inhibition of the M-current. J Physiol 332:223-262
3. Berridge CW, Waterhouse BD (2003) The locus coeruleus-noradrenergic system: modulation of behavioral state and state-dependent cognitive processes. Brain Res Brain Res Rev 42:33-84
4. Berridge CW, Schmeichel BE, España RA (2012) Noradrenergic modulation of wakefulness/arousal. Sleep Med Rev 16:187-197
5. Brown DA (1983) Slow cholinergic excitation - a mechanism for increasing neuronal excitability. Trends Neurosci 6:302-306
6. Constanti A, Brown DA (1981) M-currents in voltage-clamped mammalian sympathetic neurones. Neurosci Lett 24:289-294
7. Dawson LF, Phillips JK, Finch PM, Inglis JJ, Drummond PD (2010) Expression of α1-adrenoceptors on peripheral nociceptive neurons. Neuroscience 175:300-314
8. Day HE, Campeau S, Watson SJ Jr, Akil H (1997) Distribution of alpha 1a-, alpha 1b- and alpha 1d-adrenergic receptor mRNA in the rat brain and spinal cord. J Chem Neuroanat 13:115-139
9. Delmas P, Brown DA (2005) Pathways modulating neural KCNQ/M (Kv7) potassium channels. Nat Rev Neurosci 6:850-862
10. + currents. J Neurosci 18:5170-5179
11. Filippov AK, Brown DA, Barnard EA (2000) The P2Y(1) receptor closes the N-type Ca(2+) channel in neurones, with both adenosine triphosphates and diphosphates as potent agonists. Br J Pharmacol 129:1063-1066
12. Filippov AK, Simon J, Barnard EA, Brown DA (2010) The scaffold protein NHERF2 determines the coupling of P2Y1 nucleotide and mGluR5 glutamate receptor to different ion channels in neurons. J Neurosci 30:11068-11072
13. Gibbs ME, Summers RJ (2002) Role of adrenoceptor subtypes in memory consolidation. Prog Neurobiol 67:345-391
14. Grayson TH, Ellis JM, Chen S, Graham RM, Brown RD, Hill CE (1998) Immunohistochemical localisation of alpha1B-adrenergic receptors in the rat iris. Cell Tissue Res 293:435-444
15. Hawrylyshyn KA, Michelotti GA, Cogé F, Guénin SP, Schwinn DA (2004) Update on human alpha1-adrenoceptor subtype signaling and genomic organization. Trends Pharmacol Sci 25:449-455
16. Ikeda SR (1997) Heterologous expression of receptors and signaling proteins in adult mammalian sympathetic neurons by microinjection. Methods Mol Biol 83:191-202
17. Jones LS, Gauger LL, Davis JN (1985) Anatomy of brain alpha 1-adrenergic receptors: in vitro autoradiography with [125I]-heat. J Comp Neurol 231:190-208
18. Legendre P, Dupouy B, Vincent JD (1988) Excitatory effect of noradrenaline on pacemaker cells in spinal cord primary cultures. Neuroscience 24:647-658
19. McCormick DA (1992) Cellular mechanisms underlying cholinergic and noradrenergic modulation of neuronal firing mode in the cat and guinea pig dorsal lateral geniculate nucleus. J Neurosci 12:278-289
20. McCormick DA, Pape HC, Williamson A (1991) Actions of norepinephrine in the cerebral cortex and thalamus: implications for function of the central noradrenergic system. Prog Brain Res 88:293-305
21. Ogata N, Matsuo T (1986) The effects of catecholamines on electrical activity of neurons in the guinea pig supraoptic nucleus in vitro. Brain Res 385:122-135
22. Pediani JD, MacKenzie JF, Heeley RP, Daly CJ, McGrath JC (2000) Single-cell recombinant pharmacology: bovine alpha(1a)-adrenoceptors in rat-1 fibroblasts release intracellular Ca(2+), display subtype-characteristic agonism and antagonism, and exhibit an antagonist-reversible inverse concentration-response phase. J Pharmacol Exp Ther 293:887-895
23. Pertovaara A (2006) Noradrenergic pain modulation. Prog Neurobiol 80:53-83
24. Ramos BP, Arnsten AF (2007) Adrenergic pharmacology and cognition: focus on the prefrontal cortex. Pharmacol Ther 113:523-536
25. Shibata K, Taketani K (2001) Excitatory effect of noradrenaline on rat airway parasympathetic ganglion neurons. Fukuoka Igaku Zasshi 92:377-383 (In Japanese.)
26. Stone EA, Lin Y, Rosengarten H, Kramer HK, Quartermain D (2003) Emerging evidence for a central epinephrine-innervated alpha 1-adrenergic system that regulates behavioral activation and is impaired in depression. Neuropsychopharmacology 28:1387-1399
27. 2+ channels. J Biol Chem 286:830-841