Stability of heroin, 6-monoacetylmorphine, and morphine in biological samples and validation of an LC-MS assay for delayed analyses of pharmacokinetic samples in rats

Journal of Pharmaceutical and Biomedical Analysis

Volumn 74, Issue , 2013, Pages 291-297

  Jones, Jessica M ^a   Raleigh, Michael D ^b   Pentel, Paul R ^b,c   Harmon, Theresa M ^c   Keyler, Daniel E ^a,c   Remmel, Rory P ^a   Birnbaum, Angela K ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c MINNEAPOLIS MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

Assay validation; Heroin; Morphine; Rat; Stability

Indexed keywords

DIAMORPHINE; MORPHINE; MORPHINE 6 ACETATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; DEGRADATION; HEMOLYSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; RAT; SOLID PHASE EXTRACTION; STORAGE TEMPERATURE; TISSUE LEVEL;

ANIMALS; CATTLE; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; HEROIN; HUMANS; MALE; MASS SPECTROMETRY; MORPHINE; MORPHINE DERIVATIVES; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 84871760242     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.10.033     Document Type: Article

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