Methanol extract of Myelophycus caespitosus inhibits the inflammatory response in lipopolysaccharide-stimulated BV2 microglial cells by downregulating NF-κb via inhibition of the akt signaling pathway

Tropical Journal of Pharmaceutical Research

Volumn 11, Issue 6, 2012, Pages 917-924

  Jayasooriya, Rajapaksha Gendara Prasad ^a   Kang, Chang Hee ^a   Jang, Yeon Jeong ^a   Kang, Sang Hyuck ^a   Dilshara, Matharage Gayani ^a   Choi, Yung Hyun ^b   Moon, Dong Oh ^c   Kim, Gi Young ^a  

^a Jeju National University   (South Korea)

^b Dong Eui University   (South Korea)

^c Department of Biology Education   (South Korea)

Author keywords

Myelophycus caespitosus; Nitric oxide; Nuclear factor B; Prostaglandin E2

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; METHANOL; MYELOPHYCUS CAESPITOSUS EXTRACT; NITRIC OXIDE; PLANT EXTRACT; PROSTAGLANDIN E2; PROTEIN KINASE B; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL NUCLEUS; CELL STIMULATION; CONTROLLED STUDY; CYCLOOXYGENASE 2 GENE; CYTOTOXICITY; DOWN REGULATION; DRUG ISOLATION; ENZYME DEGRADATION; ENZYME IMMUNOASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; INDUCIBLE NITRIC OXIDE SYNTHASE GENE; INTRACELLULAR TRANSPORT; MEDICINAL PLANT; MICROGLIA; MOUSE; MYELOPHYCUS CAESPITOSUS; NONHUMAN; PROSTAGLANDIN RELEASE; PROTEIN DEPHOSPHORYLATION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; REGULATOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

EID: 84871743815     PISSN: 15965996     EISSN: 15969827     Source Type: Journal    
DOI: 10.4314/tjpr.v11i6.7     Document Type: Article

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