Differences in cytokine production in human macrophages and in virulence in mice are attributable to the acidic polymerase protein of highly pathogenic influenza A virus subtype H5N1

Journal of Infectious Diseases

Volumn 207, Issue 2, 2013, Pages 262-271

  Sakabe, Saori ^a,e   Takano, Ryo ^a   Nagamura Inoue, Tokiko ^b   Yamashita, Naohide ^c   Nidom, Chairul A ^f   Quynh Le, Mai Thi ^g   Iwatsuki Horimoto, Kiyoko ^a   Kawaoka, Yoshihiro ^a,d,e,h  

^a Division of Virology   (Japan)

^b University of Tokyo   (Japan)

^c Department of Advanced Medical Science ^*  (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^f NATIONAL INSTITUTE OF HYGIENE AND EPIDEMIOLOGY   (Viet Nam)

^g National Institute of Hygiene and Epidemiology   (Viet Nam)

^h UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

cytokine; H5N1 virus; human macrophages; Hypercytokinemia; Immune response; Microarray; virulence

Indexed keywords

CYTOKINE;

ARTICLE; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; CYTOKINE STORM; FEMALE; HUMAN; HUMAN CELL; INDONESIA; INFLUENZA A (H5N1); INFLUENZA VIRUS A H5N1; MACROPHAGE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; VIET NAM; VIRUS VIRULENCE;

ANIMALS; CYTOKINES; EPITHELIAL CELLS; FEMALE; HEK293 CELLS; HUMANS; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA, HUMAN; MACROPHAGES; MADIN DARBY CANINE KIDNEY CELLS; MICE; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE INFECTIONS; REASSORTANT VIRUSES; RNA REPLICASE; VIRAL PROTEINS; VIRULENCE;

EID: 84871737446     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jis523     Document Type: Article

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