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Volumn 23, Issue 1, 2013, Pages 11-19

Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene

Author keywords

Bulgarians; genome wide association study; hedgehog acyltransferase; schizophrenia; single nucleotide polymorphism

Indexed keywords

ADULT; AGED; ARTICLE; BULGARIA; CONTROLLED STUDY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; INTRON; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; POPULATION RESEARCH; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84871725665     PISSN: 09558829     EISSN: 14735873     Source Type: Journal    
DOI: 10.1097/YPG.0b013e3283586343     Document Type: Article
Times cited : (18)

References (41)
  • 3
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ (2005). Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 4
    • 0035183944 scopus 로고    scopus 로고
    • Genetic insights into the neurodevelopmental hypothesis of schizophrenia
    • Bassett AS, Chow EW, O'neill S, Brzustowicz LM (2001). Genetic insights into the neurodevelopmental hypothesis of schizophrenia. Schizophr Bull 27:417-430.
    • (2001) Schizophr Bull , vol.27 , pp. 417-430
    • Bassett, A.S.1    Chow, E.W.2    O'Neill, S.3    Brzustowicz, L.M.4
  • 5
    • 10844288845 scopus 로고    scopus 로고
    • Influence of diagnostic classification on gender ratio in schizophrenia - A meta-analysis of youths hospitalized for psychosis
    • Beauchamp G, Gagnon A (2004). Influence of diagnostic classification on gender ratio in schizophrenia - a meta-analysis of youths hospitalized for psychosis. Soc Psychiatry Psychiatr Epidemiol 39:1017-1022.
    • (2004) Soc Psychiatry Psychiatr Epidemiol , vol.39 , pp. 1017-1022
    • Beauchamp, G.1    Gagnon, A.2
  • 6
    • 84857039605 scopus 로고    scopus 로고
    • Genome-wide association studies of schizophrenia: Does bigger lead to better results?
    • Bergen SE, Petryshen TL (2012). Genome-wide association studies of schizophrenia: does bigger lead to better results? Curr Opin Psychiatry 25:76-82.
    • (2012) Curr Opin Psychiatry , vol.25 , pp. 76-82
    • Bergen, S.E.1    Petryshen, T.L.2
  • 7
    • 60749112924 scopus 로고    scopus 로고
    • Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population
    • Betcheva ET, Mushiroda T, Takahashi A, Kubo M, Karachanak SK, Zaharieva IT, et al. (2009). Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population. J Hum Genet 54:98-107.
    • (2009) J Hum Genet , vol.54 , pp. 98-107
    • Betcheva, E.T.1    Mushiroda, T.2    Takahashi, A.3    Kubo, M.4    Karachanak, S.K.5    Zaharieva, I.T.6
  • 8
    • 62049085783 scopus 로고    scopus 로고
    • Making a grade: Sonic Hedgehog signalling and the control of neural cell fate
    • Briscoe J (2009). Making a grade: Sonic Hedgehog signalling and the control of neural cell fate. EMBO J 28:457-465.
    • (2009) EMBO J , vol.28 , pp. 457-465
    • Briscoe, J.1
  • 9
    • 39149131047 scopus 로고    scopus 로고
    • No association between schizophrenia and polymorphisms of the PlexinA2 gene in Chinese Han Trios
    • Budel S, Shim SO, Feng Z, Zhao H, Hisama F, Strittmatter SM (2008). No association between schizophrenia and polymorphisms of the PlexinA2 gene in Chinese Han Trios. Schizophr Res 99:365-366.
    • (2008) Schizophr Res , vol.99 , pp. 365-366
    • Budel, S.1    Shim, S.O.2    Feng, Z.3    Zhao, H.4    Hisama, F.5    Strittmatter, S.M.6
  • 10
    • 0038811923 scopus 로고    scopus 로고
    • Microarray technology: A review of new strategies to discover candidate vulnerability genes in psychiatric disorders
    • Bunney WE, Bunney BG, Vawter MP, Tomita H, Li J, Evans SJ, et al. (2003). Microarray technology: a review of new strategies to discover candidate vulnerability genes in psychiatric disorders. Am J Psychiatry 160:657-666.
    • (2003) Am J Psychiatry , vol.160 , pp. 657-666
    • Bunney, W.E.1    Bunney, B.G.2    Vawter, M.P.3    Tomita, H.4    Li, J.5    Evans, S.J.6
  • 11
    • 0037337441 scopus 로고    scopus 로고
    • Two NOTCH4 polymorphisms and their relation to schizophrenia susceptibility and different personality traits
    • Carmine A, Chheda MG, Jonsson EG, Sedvall GC, Farde L, Gustavsson JP, et al. (2003). Two NOTCH4 polymorphisms and their relation to schizophrenia susceptibility and different personality traits. Psychiatr Genet 13:23-28.
    • (2003) Psychiatr Genet , vol.13 , pp. 23-28
    • Carmine, A.1    Chheda, M.G.2    Jonsson, E.G.3    Sedvall, G.C.4    Farde, L.5    Gustavsson, J.P.6
  • 12
    • 0035860538 scopus 로고    scopus 로고
    • Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal
    • Chamoun Z, Mann RK, Nellen D, Von Kessler DP, Bellotto M, Beachy PA, et al. (2001). Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal. Science 293:2080-2084.
    • (2001) Science , vol.293 , pp. 2080-2084
    • Chamoun, Z.1    Mann, R.K.2    Nellen, D.3    Von Kessler, D.P.4    Bellotto, M.5    Beachy, P.A.6
  • 13
    • 13044281675 scopus 로고    scopus 로고
    • A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2
    • Detera-Wadleigh SD, Badner JA, Berrettini WH, Yoshikawa T, Goldin LR, Turner G, et al. (1999). A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2. Proc Natl Acad Sci USA 96:5604-5609.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5604-5609
    • Detera-Wadleigh, S.D.1    Badner, J.A.2    Berrettini, W.H.3    Yoshikawa, T.4    Goldin, L.R.5    Turner, G.6
  • 14
    • 77955974092 scopus 로고    scopus 로고
    • The psychosis susceptibility gene ZNF804A: Associations, functions, and phenotypes
    • Donohoe G, Morris DW, Corvin A (2010). The psychosis susceptibility gene ZNF804A: associations, functions, and phenotypes. Schizophr Bull 36:904-909.
    • (2010) Schizophr Bull , vol.36 , pp. 904-909
    • Donohoe, G.1    Morris, D.W.2    Corvin, A.3
  • 17
    • 0036861218 scopus 로고    scopus 로고
    • Prevalence and incidence studies of schizophrenic disorders: A systematic review of the literature
    • Goldner EM, Hsu L, Waraich P, Somers JM (2002). Prevalence and incidence studies of schizophrenic disorders: a systematic review of the literature. Can J Psychiatry 47:833-843.
    • (2002) Can J Psychiatry , vol.47 , pp. 833-843
    • Goldner, E.M.1    Hsu, L.2    Waraich, P.3    Somers, J.M.4
  • 18
    • 0033364825 scopus 로고    scopus 로고
    • A genome-wide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci
    • Hovatta I, Varilo T, Suvisaari J, Terwilliger JD, Ollikainen V, Arajarvi R, et al. (1999). A genome-wide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci. Am J Hum Genet 65:1114-1124.
    • (1999) Am J Hum Genet , vol.65 , pp. 1114-1124
    • Hovatta, I.1    Varilo, T.2    Suvisaari, J.3    Terwilliger, J.D.4    Ollikainen, V.5    Arajarvi, R.6
  • 19
    • 27744583597 scopus 로고    scopus 로고
    • Hedgehog signaling pathway and gastric cancer
    • Katoh Y, Katoh M (2005). Hedgehog signaling pathway and gastric cancer. Cancer Biol Ther 4:1050-1054.
    • (2005) Cancer Biol Ther , vol.4 , pp. 1050-1054
    • Katoh, Y.1    Katoh, M.2
  • 20
    • 0034027773 scopus 로고    scopus 로고
    • At issue: A default analysis for schizophrenia research
    • discussion 163-165
    • Kirkpatrick B, Ryan WG (2000). At issue: a default analysis for schizophrenia research. Schizophr Bull 26:157-161, discussion 163-165.
    • (2000) Schizophr Bull , vol.26 , pp. 157-161
    • Kirkpatrick, B.1    Ryan, W.G.2
  • 23
    • 34547998501 scopus 로고    scopus 로고
    • High-throughput genotyping
    • Lee JE (2007). High-throughput genotyping. Forum Nutr 60:97-101.
    • (2007) Forum Nutr , vol.60 , pp. 97-101
    • Lee, J.E.1
  • 24
    • 0036308284 scopus 로고    scopus 로고
    • Schizophrenia as a disorder of neurodevelopment
    • Lewis DA, Levitt P (2002). Schizophrenia as a disorder of neurodevelopment. Annu Rev Neurosci 25:409-432.
    • (2002) Annu Rev Neurosci , vol.25 , pp. 409-432
    • Lewis, D.A.1    Levitt, P.2
  • 26
    • 33646229252 scopus 로고    scopus 로고
    • Identification of the semaphorin receptor PLXNA2 as a candidate for susceptibility to schizophrenia
    • Mah S, Nelson MR, Delisi LE, Reneland RH, Markward N, James MR, et al. (2006). Identification of the semaphorin receptor PLXNA2 as a candidate for susceptibility to schizophrenia. Mol Psychiatry 11:471-478.
    • (2006) Mol Psychiatry , vol.11 , pp. 471-478
    • Mah, S.1    Nelson, M.R.2    Delisi, L.E.3    Reneland, R.H.4    Markward, N.5    James, M.R.6
  • 27
    • 0035183947 scopus 로고    scopus 로고
    • Neural development, cell-cell signaling, and the ''two-hit'' hypothesis of schizophrenia
    • Maynard TM, Sikich L, Lieberman JA, Lamantia AS (2001). Neural development, cell-cell signaling, and the ''two-hit'' hypothesis of schizophrenia. Schizophr Bull 27:457-476.
    • (2001) Schizophr Bull , vol.27 , pp. 457-476
    • Maynard, T.M.1    Sikich, L.2    Lieberman, J.A.3    Lamantia, A.S.4
  • 28
    • 4243057297 scopus 로고    scopus 로고
    • A systematic review of the incidence of schizophrenia: The distribution of rates and the influence of sex, urbanicity, migrant status and methodology
    • Mcgrath J, Saha S, Welham J, El Saadi O, Maccauley C, Chant D (2004). A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodology. BMC Med 2:13.
    • (2004) BMC Med , vol.2 , pp. 13
    • McGrath, J.1    Saha, S.2    Welham, J.3    El Saadi, O.4    MacCauley, C.5    Chant, D.6
  • 29
    • 0026697456 scopus 로고
    • Lower incidence and increased male: Female ratio in schizophrenia
    • Nicole L, Lesage A, Lalonde P (1992). Lower incidence and increased male : female ratio in schizophrenia. Br J Psychiatry 161:556-557.
    • (1992) Br J Psychiatry , vol.161 , pp. 556-557
    • Nicole, L.1    Lesage, A.2    Lalonde, P.3
  • 31
    • 0842329756 scopus 로고    scopus 로고
    • The molecular genetics of schizophrenia: New findings promise new insights
    • Owen MJ, Williams NM, O'Donovan MC (2004). The molecular genetics of schizophrenia: new findings promise new insights. Mol Psychiatry 9:14-27.
    • (2004) Mol Psychiatry , vol.9 , pp. 14-27
    • Owen, M.J.1    Williams, N.M.2    O'Donovan, M.C.3
  • 32
    • 0033754542 scopus 로고    scopus 로고
    • Genetic and epigenetic control of midbrain dopaminergic neuron development
    • Perrone-Capano C, Di Porzio U (2000). Genetic and epigenetic control of midbrain dopaminergic neuron development. Int J Dev Biol 44: 679-687.
    • (2000) Int J Dev Biol , vol.44 , pp. 679-687
    • Perrone-Capano, C.1    Di Porzio, U.2
  • 34
    • 33745441250 scopus 로고    scopus 로고
    • Schizophrenia: An integrative approach to modelling a complex disorder
    • Robertson GS, Hori SE, Powell KJ (2006). Schizophrenia: an integrative approach to modelling a complex disorder. J Psychiatry Neurosci 31:157-167.
    • (2006) J Psychiatry Neurosci , vol.31 , pp. 157-167
    • Robertson, G.S.1    Hori, S.E.2    Powell, K.J.3
  • 35
    • 33646522416 scopus 로고    scopus 로고
    • Gene regulation by hypoxia and the neurodevelopmental origin of schizophrenia
    • Schmidt-Kastner R, Van Os J, Steinbusch HWM, Schmitz C (2006). Gene regulation by hypoxia and the neurodevelopmental origin of schizophrenia. Schizophr Res 84:253-271
    • (2006) Schizophr Res , vol.84 , pp. 253-271
    • Schmidt-Kastner, R.1    Van Os, J.2    Hwm, S.3    Schmitz, C.4
  • 36
    • 10744227091 scopus 로고    scopus 로고
    • A review and new report of medial temporal lobe dysfunction as a vulnerability indicator for schizophrenia: A magnetic resonance imaging morphometric family study of the parahippocampal gyrus
    • Seidman LJ, Pantelis C, Keshavan MS, Faraone SV, Goldstein JM, Horton NJ, et al. (2003). A review and new report of medial temporal lobe dysfunction as a vulnerability indicator for schizophrenia: a magnetic resonance imaging morphometric family study of the parahippocampal gyrus. Schizophr Bull 29:803-830
    • (2003) Schizophr Bull , vol.29 , pp. 803-830
    • Seidman, L.J.1    Pantelis, C.2    Keshavan, M.S.3    Faraone, S.V.4    Goldstein, J.M.5    Horton, N.J.6
  • 37
    • 0036788337 scopus 로고    scopus 로고
    • Genetics and etiopathophysiology of schizophrenia
    • Sobell JL, Mikesell MJ, Mcmurray CT (2002). Genetics and etiopathophysiology of schizophrenia. Mayo Clin Proc 77:1068-1082.
    • (2002) Mayo Clin Proc , vol.77 , pp. 1068-1082
    • Sobell, J.L.1    Mikesell, M.J.2    McMurray, C.T.3
  • 38
    • 33846642542 scopus 로고    scopus 로고
    • The genetics of schizophrenia
    • Sullivan PF (2005). The genetics of schizophrenia. PLoS Med 2:e212
    • (2005) PLoS Med , vol.2
    • Sullivan, P.F.1
  • 39
    • 39149118971 scopus 로고    scopus 로고
    • Genetic examination of the PLXNA2 gene in Japanese and Chinese people with schizophrenia
    • Takeshita M, Yamada K, Hattori E, Iwayama Y, Toyota T, Iwata Y, et al. (2008). Genetic examination of the PLXNA2 gene in Japanese and Chinese people with schizophrenia. Schizophr Res 99:359-364.
    • (2008) Schizophr Res , vol.99 , pp. 359-364
    • Takeshita, M.1    Yamada, K.2    Hattori, E.3    Iwayama, Y.4    Toyota, T.5    Iwata, Y.6
  • 40
    • 34548336745 scopus 로고    scopus 로고
    • Dopamine genes and schizophrenia: Case closed or evidence pending?
    • Talkowski ME, Bamne M, Mansour H, Nimgaonkar VL (2007). Dopamine genes and schizophrenia: case closed or evidence pending? Schizophr Bull 33:1071-1081.
    • (2007) Schizophr Bull , vol.33 , pp. 1071-1081
    • Talkowski, M.E.1    Bamne, M.2    Mansour, H.3    Nimgaonkar, V.L.4
  • 41
    • 0036224396 scopus 로고    scopus 로고
    • Genome scans and microarrays: Converging on genes for schizophrenia?
    • Williams NM, O'Donovan MC, Owen MJ (2002). Genome scans and microarrays: converging on genes for schizophrenia? Genome Biol 3:1011.1-1011.5.
    • (2002) Genome Biol , vol.3 , pp. 10111-10115
    • Williams, N.M.1    O'Donovan, M.C.2    Owen, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.