A gene expression profile of the developing human retinal pigment epithelium

Molecular Vision

Volumn 18, Issue , 2012, Pages 2961-2975

  Zhang, Zhongyu ^a   Zhang, Yan ^a,b   Xiao, Huizhen ^a   Liang, Xiaolei ^a   Sun, Dawei ^a   Peng, Shaomin ^a  

^a THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^b Inner Mongolia Forestry General Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; RNA;

AHR GENE; ARTICLE; BESTROPHIN GENE; CELL JUNCTION; CELL MATURATION; CFTR GENE; CHRNA3 GENE; CLDN19 GENE; CONTROLLED STUDY; DNA MICROARRAY; DNA PROBE; DOWN REGULATION; FETUS; FETUS DEVELOPMENT; FIRST TRIMESTER PREGNANCY; GAS1 GENE; GENE; GENE CLUSTER; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE IDENTIFICATION; GENE SIGNATURE; GENETIC CODE; GESTATIONAL AGE; GLUT1 GENE; GLUT10 GENE; GLUT3 GENE; GLUT4 GENE; GLUT8 GENE; GLUT9 GENE; GPR143 GENE; GRAMD3 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYBRIDIZATION; LGALS8 GENE; LSR GENE; MICROARRAY ANALYSIS; MICRODISSECTION; NUCLEOTIDE SEQUENCE; PHAGOCYTOSIS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; RPE GENE; RPE65 GENE; SFRP5 GENE; SLC2A1 GENE; SLC2A10 GENE; SLC2A3 GENE; SLC2A4 GENE; SLC2A8 GENE; SLC2A9 GENE; TIGHT JUNCTION; TRANSCYTOSIS; TREND STUDY; TYRP1 GENE; UPREGULATION; VISION;

ADULT; ANIMALS; CELL DIFFERENTIATION; FEMALE; FETAL DEVELOPMENT; FETUS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GESTATIONAL AGE; HUMANS; MIDDLE AGED; MULTIGENE FAMILY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREGNANCY; REAL-TIME POLYMERASE CHAIN REACTION; RETINAL PIGMENT EPITHELIUM;

EID: 84871708029     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Strauss O. The retinal pigment epithelium in visual function. Physiol Rev 2005; 85:845-81. [PMID: 15987797].
2. Sarks SH. Ageing and degeneration in the macular region: a clinico-pathological study. Br J Ophthalmol 1976; 60:324-41. [PMID: 952802].
3. Dorey CK, Wu G, Ebenstein D, Garsd A, Weiter JJ. Cell loss in the aging retina. Relationship to lipofuscin accumulation and macular degeneration. Invest Ophthalmol Vis Sci 1989; 30:1691-9. [PMID: 2759786].
4. Dunaief JL, Dentchev T, Ying GS, Milam AH. The role of apoptosis in age-related macular degeneration. Arch Ophthalmol 2002; 120:1435-42. [PMID: 12427055].
5. Klein R, Klein BE, Jensen SC, Meuer SM. The five-year incidence and progression of age-related maculopathy: the Beaver Dam Eye Study. Ophthalmology 1997; 104:7-21. [PMID: 9022098].
6. Binder S, Krebs I, Hilgers RD, Abri A, Stolba U, Assadoulina A, Kellner L, Stanzel BV, Jahn C, Feichtinger H. Outcome of transplantation of autologous retinal pigment epithelium in age-related macular degeneration: a prospective trial. Invest Ophthalmol Vis Sci 2004; 45:4151-60. [PMID: 15505069].
7. Little CW, Castillo B, Diloreto DA, Cox C, Wyatt J, del Cerro C, del Cerro M. Transplantation of human fetal retinal pigment epithelium rescues photoreceptor cells from degeneration in the Royal College of Surgeons rat retina. Invest Ophthalmol Vis Sci 1996; 37:204-11. [PMID: 8550325].
8. Lund RD, Adamson P, Sauve Y, Keeqan DJ, Girman SV, Wang S, Winton H, Kanuqa N, Kwan AS, Beauchene L, Zerbib A, Hetherington L, Couraud PO, Coffev P, Greenwood J. Subretinal transplantation of genetically modified human cell lines attenuates loss of visual function in dystrophic rats. Proc Natl Acad Sci USA 2001; 98:9942-7. [PMID: 11504951].
9. Sauvé Y, Girman SV, Wang S, Keegan DJ, Lund RD. Preservation of visual responsiveness in the superior colliculus of RCS rats after retinal pigment epithelium cell transplantation. Neuroscience 2002; 114:389-401. [PMID: 12204208].
10. Sheedlo HJ, Li L, Turner JE. Photoreceptor cell rescue in the RCS rat by RPE transplantation: a therapeutic approach in a model of inherited retinal dystrophy. Prog Clin Biol Res 1989; 314:645-58. [PMID: 2558386].
11. da Cruz L, Chen FK, Ahmado A, Greenwood J, Coffey P. RPE transplantation and its role in retinal disease. Prog Retin Eye Res 2007; 26:598-635. [PMID: 17920328].
12. Lu B, Malcuit C, Wang S, Girman S, Francis P, Lemieux L, Lanza R, Lund R. Long-term safety and function of RPE from human embryonic stem cells in preclinical models of macular degeneration. Stem Cells 2009; 27:2126-35. [PMID: 19521979].
13. Carr AJ, Vugler AA, Hikita ST, Lawrence JM, Gias C, Chen LL, Buchholz DE, Ahmado A, Semo M, Smart MJ, Hasan S, da Cruz L, Johnson LV, Cleqq DO, Coffey PJ. Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat. PLoS One 2009; 4:e8152- [PMID: 19997644].
14. Schwartz SD, Hubschman JP, Heilwell G, Franco-Cardenas V, Pan CK, Ostrick RM, Mickunas E, Gay R, Klimanskaya I, Lanza R. Embryonic stem cell trials for macular degeneration: a preliminary report. Lancet 2012; 379:713-20. [PMID: 22281388].
15. Tezel TH, Del Priore LV, Berger AS, Kaplan HJ. Adult retinal pigment epithelial transplantation in exudative age-related macular degeneration. Am J Ophthalmol 2007; 143:584-95. [PMID: 17303061].
16. Idelson M, Alper R, Obolensky A, Ben-Shushan E, Hemo I, Yachimovich-Cohen N, Khaner H, Smith Y, Wiser O, Gropp M, Cohen MA, Even-Ram S, Berman-Zaken Y, Matzrafi L, Rechavi G, Banin E, Reubinoff B. Directed differentiation of human embryonic stem cells into functional retinal pigment epithelium cells. Cell Stem Cell 2009; 5:396-408. [PMID: 19796620].
17. Liao JL, Yu J, Huang K, Hu J, Diemer T, Ma Z, Dvash T, Yang XJ, Travis GH, Williams DS, Bok D, Fan G. Molecular Signature of Primary Retinal Pigment Epithelium and stem- cell derived RPE cells. Hum Mol Genet 2010; 19:4229-38. [PMID: 20709808].
18. Stroeva OG, Mitashov VI. Retinal pigment epithelium: proliferation and differentiation during development and regeneration. Int Rev Cytol 1983; 83:221-93. [PMID: 6315626].
19. Leung YF, Ma P, Dowling JE. Gene expression profiling of zebrafish embryonic retinal pigment epithelium in vivo. Invest Ophthalmol Vis Sci 2007; 48:881-90. [PMID: 17251491].
20. Rizzolo LJ, Chen X, Weitzman M, Sun R, Zhang H. Analysis of the RPE transcriptome reveals dynamic changes during the development of the outer blood-retinal barrier. Mol Vis 2007; 13:1259-73. [PMID: 17679949].
21. Sun R, Peng S, Chen X, Zhang H, Rizzolo LJ. Diffusible retinal secretions regulate the expression of tight junctions and other diverse functions of the retinal pigment epithelium. Mol Vis 2008; 14:2237-62. [PMID: 19057659].
22. Strunnikova NV, Maminishkis A, Barb JJ, Wang F, Zhi C, Sergeev Y, Chen W, Edwards AO, Stambolian D, Abecasis G, Swaroop A, Munson PJ, Miller SS. Transcriptome analysis and molecular signature of human retinal pigment epithelium. Hum Mol Genet 2010; 19:2468-86. [PMID: 20360305].
23. Rando RR. The biochemistry of the visual cycle. Chem Rev 2001; 101:1881-96. [PMID: 11710234].
24. Saari JC, Crabb JW. Genetic and proteomic analyses of the mouse visual cycle. In: LM Chalupa, RW Williams, editors. Eye, Retina, and Visual System of the Mouse. Cambridge: MIT Press; 2008. p.721-25.
25. Kevany BM, Palczewski K. Phagocytosis of Retinal Rod and Cone Photoreceptors. Physiology (Bethesda) 2010; 25:8-15. [PMID: 20134024].
26. Herman KG, Steinberg RH. Phagosome movement and the diurnal pattern of phagocytosis in the tapetal retinal pigment epithelium of the opossum. Invest Ophthalmol Vis Sci 1982; 23:277-90. [PMID: 7107156].
27. Hartsock A, Nelson WJ. Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. Biochim Biophys Acta 2008; 1778:660-9. [PMID: 17854762].
28. Paris L, Bazzoni G. The protein interaction network of the epithelial junctional complex: a system-level analysis. Mol Biol Cell 2008; 19:5409-21. [PMID: 18923145].
29. Van Itallie CM, Anderson JM. Claudins and Epithelial Paracellular Transport. Annu Rev Physiol 2006; 68:403-29. [PMID: 16460278].
30. Williams CD, Rizzolo LJ. Remodeling of junctional complexes during the development of the outer blood-retinal barrier. Anat Rec 1997; 249:380-8. [PMID: 9372172].
31. Booij JC, ten Brink JB, Swagemakers SM, Verkerk AJ, Essing AH, van der Spek PJ, Bergen AA. A new strategy to identify and annotate human RPE-specific gene expression. PLoS One 2010; 5:e9341. [PMID: 20479888].
32. Peng S, Rao VS, Adelman RA, Rizzolo LJ. Claudin-19 and the barrier properties of the human retinal pigment epithelium. Invest Ophthalmol Vis Sci 2011; 52:1392-403. [PMID: 21071746].
33. Konrad M, Schaller A, Seelow D, Pandey AV, Waldegger S, Lesslauer A, Vitzthum H, Suzuki Y, Luk JM, Becker C, Schlingmann KP, Schmid M, Rodriguez-Soriano J, Ariceta G, Cano F, Enriguez R, Juppner H, Bakkaloglu SA, Hediger MA, Gallati S, Neuhauss SC, Nurnberg P, Weber S. Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement. Am J Hum Genet 2006; 79:949-57. [PMID: 17033971].
34. Economopoulou M, Hammer J, Wang F, Fariss R, Maminishkis A, Miller SS. Expression, localization, and function of junctional adhesion molecule-C (JAM-C) in human retinal pigment epithelium. Invest Ophthalmol Vis Sci 2009; 50:1454-63. [PMID: 19060272].
35. Bauer HC, Traweger A, Zweimueller-Mayer J, Lehner C, Tempfer H., Krizbai, Wilhelm I, Bauer H. New aspects of the molecular constituents of tissue barriers. J Neural Transm 2011; 118:7-21. [PMID: 20865434].
36. +) ATPase deduced from a cDNA. Nature 1986; 321:429-31. [PMID: 3012356].
37. +/ K+-ATPase. Biochem J 2002; 364:293-9. [PMID: 11988103].
38. Wimmers S, Karl MO, Strauss O. Ion channels in the RPE. Prog Retin Eye Res 2007; 26:263-301. [PMID: 17258931].
39. Hartzell C, Qu Z, Putzier I, Artinian L, Chien LT, Cui Y. Looking chloride channels straight in the eye: bestrophins, lipofuscinosis, and retinal degeneration. Physiology (Bethesda) 2005; 20:292-302. [PMID: 16174869].
40. Sheppard DN, Welsh MJ. Structure and function of the CFTR chloride channel. Physiol Rev 1999; 79:1 Suppl S23-45. [PMID: 9922375].
41. Lee CS, May NR, Fan CM. Transdifferentiation of the ventral retinal pigmented epithelium to neural retina in the growth arrest specific gene 1 mutant. Dev Biol 2001; 236:17-29. [PMID: 11456441].
42. Stroeva OG, Mitashov VI. Retinal pigment epithelium: proliferation and differentiation during development and regenera- tion. Int Rev Cytol 1983; 83:221-93. [PMID: 6315626].
43. Lopes VS, Wasmeier C, Seabra MC, Futter CE. Melanosome maturation defect in Rab38-deficient retinal pigment epithe- lium results in instability of immature melanosomes during transient melanogenesis. Mol Biol Cell 2007; 18:3914-27. [PMID: 17671165].
44. Sarna T, Burke JM, Korytowski W, Rózanowska M, Skumatz CM, Zareba A, Zareba M. Loss of melanin from human RPE with aging: possible role of melanin photooxidation. Exp Eye Res 2003; 76:89-98. [PMID: 12589778].
45. Memoli S, Napolitano A, d'Ischia M, Misuraca G, Palumbo A, Prota G. Diffusible melanin-related metabolites are potent inhibitors of lipid peroxidation. Biochim Biophys Acta 1997; 1346:61-8. [PMID: 9187303].
46. Zadlo A, Rozanowska MB, Burke JM, Sarna TJ. Photo- bleaching of retinal pigment epithelium melanosomes reduces their ability to inhibit iron-induced peroxidation of lipids. Pigment Cell Res 2007; 20:52-60. [PMID: 17250548].
47. Hong L, Simon JD. Current understanding of the binding sites, capacity, affinity, and biological significance of metals in melanin. J Phys Chem B 2007; 111:7938-47. [PMID: 17580858].
48. Yerger VB, Malone RE. Melanin and nicotine: A review of the literature. Nicotine Tob Res 2006; 8:487-98. [PMID: 16920646].
49. Bridges CD. Distribution of retinol isomerase in vertebrate eyes and its emergence during retinal development. Vision Res 1989; 29:1711-7. [PMID: 2631392].
50. Feng WANG, Huiming LI, Wenwen LIU, Ping XU. Xu Ping, Hu Gengxi, Cheng Yidong, JIA Libin, Huang Qian. Gene expression rofiles of the developing human retina. Chin Sci Bull 2004; 49:2277-84.
51. Peng S, Gan G, Rao VS, Adelman RA, Rizzolo LJ. Effects of proinflammatory cytokines on the claudin-19 rich tight junctions of human retinal pigment epithelium. Invest Ophthalmol Vis Sci 2012; 53:5016-28. [PMID: 22761260].
52. Quinn RH, Miller SS. Ion transport mechanisms in native human retinal pigment epithelium. Invest Ophthalmol Vis Sci 1992; 33:3513-27. [PMID: 1334477].
53. Luo Y, Fukuhara M, Weitzman M, Rizzolo LJ. Expression of JAM-A, AF-6, PAR-3 and PAR-6 during the assembly and remodeling of RPE tight junctions. Brain Res 2006; 1110:55-63. [PMID: 16859655].
54. Ban Y, Rizzolo LJ. Regulation of glucose transporters during development of the retinal pigment epithelium. Brain Res Dev Brain Res 2000; 121:89-95. [PMID: 10837896].
55. Maminishkis A, Chen S, Jalickee S, Banzon T, Shi G, Wang FE, Ehalt T, Hammer JA, Miller SS. Confluent mono - layers of cultured human fetal retinal pigment epithelium exhibit morphology and physiology of native tissue. Invest Ophthalmol Vis Sci 2006; 47:3612-24. [PMID: 16877436].