Lsd1 and Lsd2 Control Programmed Replication Fork Pauses and Imprinting in Fission Yeast

Cell Reports

Volumn 2, Issue 6, 2012, Pages 1513-1520

  Holmes, Allyson ^a   Roseaulin, Laura ^b   Schurra, Catherine ^a   Waxin, Herve ^a   Lambert, Sarah ^c   Zaratiegui, Mikel ^d   Martienssen, Robert A ^e   Arcangioli, Benoit ^a  

^a INSTITUT PASTEUR   (France)

^b INSTITUT CURIE   (France)

^c INSTITUT CURIE   (France)

^d RUTGERS UNIVERSITY   (United States)

^e Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); ENZYME; LYSINE SPECIFIC DEMETHYLASE 1; LYSINE SPECIFIC DEMETHYLASE 2; PROTEIN; PROTEIN SWI1; PROTEIN SWI3; PROTEIN TIMELESS; REPETITIVE DNA; UNCLASSIFIED DRUG;

ARTICLE; CELL DIVISION; CONTROLLED STUDY; DNA REPLICATION; ENZYME ACTIVITY; GENE LOCUS; GENE PRODUCT; GENOME IMPRINTING; MATING TYPE; NONHUMAN; PRIORITY JOURNAL; REPLICATION FORK; SCHIZOSACCHAROMYCES POMBE; SEQUENCE HOMOLOGY;

CELL CYCLE PROTEINS; DNA REPLICATION; DNA, FUNGAL; DNA-BINDING PROTEINS; GENETIC LOCI; GENOMIC IMPRINTING; MULTIENZYME COMPLEXES; OXIDOREDUCTASES, N-DEMETHYLATING; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS;

EUKARYOTA; MAMMALIA; SCHIZOSACCHAROMYCES POMBE; SCHIZOSACCHAROMYCETACEAE;

EID: 84871707126     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2012.10.011     Document Type: Article

References (51)

1. Ahn J.S., Osman F., Whitby M.C. Replication fork blockage by RTS1 at an ectopic site promotes recombination in fission yeast. EMBO J. 2005, 24:2011-2023.
2. Arcangioli B. A site- and strand-specific DNA break confers asymmetric switching potential in fission yeast. EMBO J. 1998, 17:4503-4510.
3. Arcangioli B., Klar A.J. A novel switch-activating site (SAS1) and its cognate binding factor (SAP1) required for efficient mat1 switching in Schizosaccharomyces pombe. EMBO J. 1991, 10:3025-3032.
4. Arcangioli B., Copeland T.D., Klar A.J. Sap1, a protein that binds to sequences required for mating-type switching, is essential for viability in Schizosaccharomyces pombe. Mol. Cell. Biol. 1994, 14:2058-2065.
5. Bähler J., Wu J.Q., Longtine M.S., Shah N.G., McKenzie A., Steever A.B., Wach A., Philippsen P., Pringle J.R. Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe. Yeast 1998, 14:943-951.
6. Beach D.H. Cell type switching by DNA transposition in fission yeast. Nature 1983, 305:682-687.
7. Brewer B.J., Fangman W.L. A replication fork barrier at the 3' end of yeast ribosomal RNA genes. Cell 1988, 55:637-643.
8. Cam H.P., Sugiyama T., Chen E.S., Chen X., FitzGerald P.C., Grewal S.I. Comprehensive analysis of heterochromatin- and RNAi-mediated epigenetic control of the fission yeast genome. Nat. Genet. 2005, 37:809-819.
9. Ciccone D.N., Su H., Hevi S., Gay F., Lei H., Bajko J., Xu G., Li E., Chen T. KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. Nature 2009, 461:415-418.
10. Dalgaard J.Z., Klar A.J. Orientation of DNA replication establishes mating-type switching pattern in S. pombe. Nature 1999, 400:181-184.
11. Dalgaard J.Z., Klar A.J. swi1 and swi3 perform imprinting, pausing, and termination of DNA replication in S. pombe. Cell 2000, 102:745-751.
12. Dalgaard J.Z., Klar A.J. A DNA replication-arrest site RTS1 regulates imprinting by determining the direction of replication at mat1 in S. pombe. Genes Dev. 2001, 15:2060-2068.
13. Egel R., Beach D.H., Klar A.J. Genes required for initiation and resolution steps of mating-type switching in fission yeast. Proc. Natl. Acad. Sci. USA 1984, 81:3481-3485.
14. Eydmann T., Sommariva E., Inagawa T., Mian S., Klar A.J., Dalgaard J.Z. Rtf1-mediated eukaryotic site-specific replication termination. Genetics 2008, 180:27-39.
15. Gordon M., Holt D.G., Panigrahi A., Wilhelm B.T., Erdjument-Bromage H., Tempst P., Bähler J., Cairns B.R. Genome-wide dynamics of SAPHIRE, an essential complex for gene activation and chromatin boundaries. Mol. Cell. Biol. 2007, 27:4058-4069.
16. Hakimi M.A., Bochar D.A., Chenoweth J., Lane W.S., Mandel G., Shiekhattar R. A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes. Proc. Natl. Acad. Sci. USA 2002, 99:7420-7425.
17. Holmes A.M., Kaykov A., Arcangioli B. Molecular and cellular dissection of mating-type switching steps in Schizosaccharomyces pombe. Mol. Cell. Biol. 2005, 25:303-311.
18. Huang J., Sengupta R., Espejo A.B., Lee M.G., Dorsey J.A., Richter M., Opravil S., Shiekhattar R., Bedford M.T., Jenuwein T., Berger S.L. p53 is regulated by the lysine demethylase LSD1. Nature 2007, 449:105-108.
19. Kaykov A., Holmes A.M., Arcangioli B. Formation, maintenance and consequences of the imprint at the mating-type locus in fission yeast. EMBO J. 2004, 23:930-938.
20. Katz D.J., Edwards T.M., Reinke V., Kelly W.G. A C. elegans LSD1 demethylase contributes to germline immortality by reprogramming epigenetic memory. Cell 2009, 137:308-320.
21. Klar A.J. Differentiated parental DNA strands confer developmental asymmetry on daughter cells in fission yeast. Nature 1987, 326:466-470.
22. Klar A.J. Lessons learned from studies of fission yeast mating-type switching and silencing. Annu. Rev. Genet. 2007, 41:213-236.
23. Klar A.J., Miglio L.M. Initiation of meiotic recombination by double-strand DNA breaks in S. pombe. Cell 1986, 46:725-731.
24. Krings G., Bastia D. Sap1p binds to Ter1 at the ribosomal DNA of Schizosaccharomyces pombe and causes polar replication fork arrest. J. Biol. Chem. 2005, 280:39135-39142.
25. Lambert S., Watson A., Sheedy D.M., Martin B., Carr A.M. Gross chromosomal rearrangements and elevated recombination at an inducible site-specific replication fork barrier. Cell 2005, 121:689-702.
26. Lan F., Zaratiegui M., Villén J., Vaughn M.W., Verdel A., Huarte M., Shi Y., Gygi S.P., Moazed D., Martienssen R.A., Shi Y. S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription. Mol. Cell 2007, 26:89-101.
27. Li F., Huarte M., Zaratiegui M., Vaughn M.W., Shi Y., Martienssen R., Cande W.Z. Lid2 is required for coordinating H3K4 and H3K9 methylation of heterochromatin and euchromatin. Cell 2008, 135:272-283.
28. Mejía-Ramírez E., Sánchez-Gorostiaga A., Krimer D.B., Schvartzman J.B., Hernández P. The mating type switch-activating protein Sap1 Is required for replication fork arrest at the rRNA genes of fission yeast. Mol. Cell. Biol. 2005, 25:8755-8761.
29. Metzger E., Wissmann M., Yin N., Müller J.M., Schneider R., Peters A.H., Günther T., Buettner R., Schüle R. LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. Nature 2005, 437:436-439.
30. Moreno S., Klar A., Nurse P. Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol. 1991, 194:795-823.
31. Nakano S., Stillman B., Horvitz H.R. Replication-coupled chromatin assembly generates a neuronal bilateral asymmetry in C. elegans. Cell 2011, 147:1525-1536.
32. Nakayama J., Rice J.C., Strahl B.D., Allis C.D., Grewal S.I. Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science 2001, 292:110-113.
33. Nicolas E., Lee M.G., Hakimi M.A., Cam H.P., Grewal S.I., Shiekhattar R. Fission yeast homologs of human histone H3 lysine 4 demethylase regulate a common set of genes with diverse functions. J. Biol. Chem. 2006, 281:35983-35988.
34. Nielsen O., Egel R. Mapping the double-strand breaks at the mating-type locus in fission yeast by genomic sequencing. EMBO J. 1989, 8:269-276.
35. Noguchi E., Noguchi C., Du L.L., Russell P. Swi1 prevents replication fork collapse and controls checkpoint kinase Cds1. Mol. Cell. Biol. 2003, 23:7861-7874.
36. Noguchi E., Noguchi C., McDonald W.H., Yates J.R., Russell P. Swi1 and Swi3 are components of a replication fork protection complex in fission yeast. Mol. Cell. Biol. 2004, 24:8342-8355.
37. Noma K., Grewal S.I. Histone H3 lysine 4 methylation is mediated by Set1 and promotes maintenance of active chromatin states in fission yeast. Proc. Natl. Acad. Sci. USA 2002, 99(Suppl 4):16438-16445.
38. Opel M., Lando D., Bonilla C., Trewick S.C., Boukaba A., Walfridsson J., Cauwood J., Werler P.J., Carr A.M., Kouzarides T., et al. Genome-wide studies of histone demethylation catalysed by the fission yeast homologues of mammalian LSD1. PLoS ONE 2007, 2:e386.
39. Perillo B., Ombra M.N., Bertoni A., Cuozzo C., Sacchetti S., Sasso A., Chiariotti L., Malorni A., Abbondanza C., Avvedimento E.V. DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression. Science 2008, 319:202-206.
40. Pryce D.W., Ramayah S., Jaendling A., McFarlane R.J. Recombination at DNA replication fork barriers is not universal and is differentially regulated by Swi1. Proc. Natl. Acad. Sci. USA 2009, 106:4770-4775.
41. Roseaulin L., Yamada Y., Tsutsui Y., Russell P., Iwasaki H., Arcangioli B. Mus81 is essential for sister chromatid recombination at broken replication forks. EMBO J. 2008, 27:1378-1387.
42. Rudolph T., Yonezawa M., Lein S., Heidrich K., Kubicek S., Schäfer C., Phalke S., Walther M., Schmidt A., Jenuwein T., Reuter G. Heterochromatin formation in Drosophila is initiated through active removal of H3K4 methylation by the LSD1 homolog SU(VAR)3-3. Mol. Cell 2007, 26:103-115.
43. Sanchez J.A., Kim S.M., Huberman J.A. Ribosomal DNA replication in the fission yeast, Schizosaccharomyces pombe. Exp. Cell Res. 1998, 238:220-230.
44. Sanders S.L., Portoso M., Mata J., Bähler J., Allshire R.C., Kouzarides T. Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage. Cell 2004, 119:603-614.
45. Sayrac S., Vengrova S., Godfrey E.L., Dalgaard J.Z. Identification of a novel type of spacer element required for imprinting in fission yeast. PLoS Genet. 2011, 7:e1001328.
46. Shi Y., Lan F., Matson C., Mulligan P., Whetstine J.R., Cole P.A., Casero R.A., Shi Y. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 2004, 119:941-953.
47. Shi Y.J., Matson C., Lan F., Iwase S., Baba T., Shi Y. Regulation of LSD1 histone demethylase activity by its associated factors. Mol. Cell 2005, 19:857-864.
48. Singh J., Klar A.J. DNA polymerase-alpha is essential for mating-type switching in fission yeast. Nature 1993, 361:271-273.
49. Sommariva E., Pellny T.K., Karahan N., Kumar S., Huberman J.A., Dalgaard J.Z. Schizosaccharomyces pombe Swi1, Swi3, and Hsk1 are components of a novel S-phase response pathway to alkylation damage. Mol. Cell. Biol. 2005, 25:2770-2784.
50. Wang Y., Zhang H., Chen Y., Sun Y., Yang F., Yu W., Liang J., Sun L., Yang X., Shi L., et al. LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer. Cell 2009, 138:660-672.
51. Zaratiegui M., Vaughn M.W., Irvine D.V., Goto D., Watt S., Bähler J., Arcangioli B., Martienssen R.A. CENP-B preserves genome integrity at replication forks paused by retrotransposon LTR. Nature 2011, 469:112-115.