Specificity and Versatility of Substrate Binding Sites in Four Catalytic Domains of Human N-Terminal Acetyltransferases

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Grauffel, Cédric ^a,b   Abboud, Angèle ^b   Liszczak, Glen ^c   Marmorstein, Ronen ^c   Arnesen, Thomas ^a   Reuter, Nathalie ^a,b  

^a UNIVERSITY OF BERGEN   (Norway)

^b Uni Research AS   (Norway)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; PEPTIDE ALPHA N ACETYLTRANSFERASE; PEPTIDE ALPHA N ACETYLTRANSFERASE 10; PEPTIDE ALPHA N ACETYLTRANSFERASE 20; PEPTIDE ALPHA N ACETYLTRANSFERASE 30; PEPTIDE ALPHA N ACETYLTRANSFERASE 50; TYROSINE; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; BINDING SITE; CATALYSIS; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR DYNAMICS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS;

ACETYL COENZYME A; AMINO ACID SEQUENCE; BINDING SITES; CATALYTIC DOMAIN; HUMANS; HYDROGEN BONDING; KINETICS; LIGANDS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; N-TERMINAL ACETYLTRANSFERASE E; N-TERMINAL ACETYLTRANSFERASES; NITROGEN; PEPTIDES; POINT MUTATION; PROTEIN BINDING; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EUKARYOTA;

EID: 84871698501     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052642     Document Type: Article

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